Etodolac Single Dose Metabolic Profile Elucidation: Pharmacokinetics and Adverse Events in Healthy Volunteers by Karen Sánchez-Luquez, Anne Michelli Reis Silveira, Salvador Sánchez-Vinces, Alex Ap. Rosini Silva, Joyce Barreto, Rhubia Bethania Socorro Lemos de Brito, Caroline de Moura Garcia, Ana Lais Vieira, Marcia Ap. Antonio, Patrícia de Oliveira Carvalho

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RDRM-YOLO: A High-Accuracy and Lightweight Rice Disease Detection Model for Complex Field Environments Based on Improved YOLOv5 by Pan Li, Jitao Zhou, Huihui Sun, Jian Zeng

“…Existing deep learning-based methods for rice leaf disease detection struggle with inadequate sensitivity to subtle disease features, high computational complexity, and degraded accuracy under complex field conditions, such as background interference and fine-grained disease variations. …”
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The Contribution of Education, Health, and Unemployment on HDI in East Java, Indonesia by Amrun Rosyid, Elok Damayanti, Sarmilah Sarmilah, ST Rohani, Syalwa Shabila

“…Future research should incorporate qualitative methods and longitudinal data to capture broader determinants of human development. …”
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Deciphering the evolutionary imprints of Camellia oleifera Abel.: delineating its distinct phylogeographic structure and demographic history through microsatellite and plastid frag... by Tao Chen, Tingting Xiang, Qian Zheng, Xuekun Kuang, Qingbo Kong, Jiasi Zhou, Heng Wang, Lijun Zhou, Shiling Feng, Ming Yuan, Hongyu Yang, Chunbang Ding

“…The integrated Approximate Bayesian Computation (ABC) and ecological niche modeling (ENM) were utilized to analyze the demographic and evolutionary history. …”
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Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic... by Wenyang Nie, Wangzheqi Zhang, Zhikai Xiahou, Yuxuan Meng, Yuhang Liu, Jingwen Zhang, Zhen Wang, Yong Wang

“…Notwithstanding therapeutic advancements, resistance to treatment remains a significant obstacle. scRNA-seq offers comprehensive insights into the immune signaling network and immunological dynamics inside the CRC’s TME.MethodsWe integrated scRNA-seq data from GEO with extensive RNA-seq data from TCGA to elucidate immunological signaling and dynamic cellular variation in the TME of CRC. …”
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Best estimate of the planetary boundary layer height from multiple remote sensing measurements by D. Zhang, J. Comstock, C. Sivaraman, K. Mo, R. Krishnamurthy, J. Tian, T. Su, Z. Li, N. Roldán-Henao

“…In this study, we use machine learning (ML) methods to produce a best-estimate PBLHT (PBLHT-BE-ML) by integrating four PBLHT estimates derived from remote sensing measurements at the Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) observatory. …”
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The ocular surface microbiome of rhesus macaques by Joelle K. Hass, Arthur G. Fernandes, Michael J. Montague, Armando Burgos-Rodriguez, Melween I. Martinez, Lauren J. N. Brent, Noah Snyder-Mackler, John Danias, Gadi Wollstein, James P. Higham, Amanda D. Melin

“…Abstract Background The ocular surface microbiota (OSM) is important for eye health, and variations in OSM composition have been associated with multiple diseases in humans. …”
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Duckweed: a starch-hyperaccumulating plant under cultivation with a combination of nutrient limitation and elevated CO2 by Ling Guo, Ling Guo, Yang Fang, Songhu Wang, Yao Xiao, Yanqiang Ding, Yanling Jin, Xueping Tian, Anping Du, Zhihua Liao, Kaize He, Shuang Chen, Yonggui Zhao, Li Tan, Zhuolin Yi, Yuqing Che, Lanchai Chen, Jinmeng Li, Leyi Zhao, Peng Zhang, Zhengbiao Gu, Fangyuan Zhang, Yan Hong, Qing Zhang, Hai Zhao

“…In this study, we integrated whole-genome sequencing, epigenomics, transcriptomics, enzyme activity, and composition variation to elucidate the mechanisms of efficient starch accumulation in duckweed in terms of starch accumulation and carbon partitioning, regulation of the expression of genes in the starch metabolic pathway, and sucrose biosynthesis and transportation.Results and discussionAlthough Landoltia punctata exhibits dramatic gene family contraction, its starch content and productivity reached 72.2% (dry basis) and 10.4 g m-2 d-1, respectively, in 10 days, equivalent to a yield of 38.0 t ha-1 y-1, under nutrient limitation treatment with elevated CO2 levels. …”
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Thermal comfort and energy related occupancy behavior in Dutch residential dwellings by Anastasios Ioannou

“…Concerning the PMV model the analysis showed that while the neutral temperatures are well predicted by the PMV method, the cold and warm sensations are not. It appears that tenants reported (on a statistically significant way) comfortable sensations while the PMV method does not predict such comfort. …”
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MLK-TR: a Multi-branch Large Kernel TRansformer for UAV-based images by Xun Li, Yuzhen Zhao, Yang Zhao, Zhun Guo, Jianjing Gao, Baoxi Yuan

“…However, due to the small size of targets captured by UAV, along with challenges such as scale variation and blurred edges, existing methods struggle to maintain high detection accuracy while ensuring efficient inference speed. …”
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Overview of RING gene family in maize (Zea mays L.): ZmRING-93 enhances drought tolerance in transgenic Arabidopsis by Xiaotian Zhang, Huili Chen, Wei Tian, Zihui Gao, Hewei Du, Shuangcheng Ding, Hongwei Wang

“…Results We employed three distinct methods and identified a total of 590 proteins. Phylogenetic analysis revealed that these proteins could be grouped into 11 separate clusters. …”
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Metabolic state uncovers prognosis insights of esophageal squamous cell carcinoma patients by Tingze Feng, Pengfei Li, Siyi Li, Yuhan Wang, Jing Lv, Tian Xia, Hoy-Jong Lee, Hai-Long Piao, Di Chen, Yegang Ma

“…Methods First, we characterized the metabolic states of cells in ESCC using single-cell transcriptome profiles of key metabolite-interacting proteins. …”
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The Impact of Celiprolol in Vascular Ehlers–Danlos Syndrome: A Systematic Review of Current Evidence by Pandit Bagus Tri Saputra, Wynne Widiarti, Paulus Parholong Siahaan, Rendra Mahardhika Putra, Johanes Nugroho Eko Putranto, Raden Mohammad Budiarto, Nadya Luthfah, Chaq El Chaq Zamzam Multazam, Mario D’Oria, Firas Farisi Alkaff

“…Methods: A comprehensive literature search was conducted across scientific databases for studies comparing celiprolol with placebo or other treatments, focusing on relevant outcomes. …”
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Exploration of beta diversity across altitude gradients in an Alpine region in Trentino using FOSS4G and a historical floristic archive by F. Geri, F. Zottele, N. La Porta, C. Tattoni, P. Zatelli, M. Ciolli, M. Ciolli

“…Future research will compare historical and contemporary floristic data, apply alternative statistical methods, and incorporate remote sensing for enhanced biodiversity assessments.…”
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Determinants of Health and Performance in Wildland Firefighters: A Narrative Review by Fabio García-Heras, Jorge Gutiérrez-Arroyo, Juan Rodríguez-Medina, Belén Carballo-Leyenda, Pilar Sánchez-Collado, Gerardo Villa-Vicente, Jose A. Rodríguez-Marroyo

“…This narrative review seeks to analyze the main factors influencing the health and performance of WFFs, with a particular focus on physical, environmental, and psychological challenges. Methods: A narrative review was performed, synthesizing data from diverse sources. …”
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Spatio-temporal dynamics and drivers of cropland ecosystem services value during the past two decades in Yangtze river economic belt, China by Hanjun Xia, Pengbo Zhang, Qi Zhang, Baofa Peng, Chenxin Zhou, Qian Zhu, Songchao Chen, Bifeng Hu

“…Clarifying the spatio-temporal variation of the cropland ecosystem service value (Crop-ESV) and understanding its main drivers are critical for maintaining and regulating cropland ecosystem functions.MethodsThus, this study systematically assessed the Crop-ESV in the Yangtze River Economic Belt (YREB) in China and mapped it at 1 km spatial resolution from 2001 to 2020. …”
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Postprandial glucose variability and clusters of sex hormones, liver enzymes, and cardiometabolic factors in a South African cohort of African ancestry by Lisa K Micklesfield, Tinashe Chikowore, Julia H Goedecke, Michèle Ramsay, Bontle Masango, Karl-Heinz Storbeck

“…Introduction This study aimed to, first, determine the clusters of sex hormones, liver enzymes, and cardiometabolic factors associated with postprandial glucose (PPG) and, second to evaluate the variation these clusters account for jointly and independently with polygenic risk scores (PRSs) in South Africans of African ancestry men and women.Research design and methods PPG was calculated as the integrated area under the curve for glucose during the oral glucose tolerance test (OGTT) using the trapezoidal rule in 794 participants from the Middle-aged Soweto Cohort. …”
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Developing supervised machine learning algorithms to classify lettuce foliar tissue samples into interpretation zones for 11 plant essential nutrients by Patrick Veazie, Hsuan Chen, Kristin Hicks, Jake Holley, Nathan Eylands, Neil Mattson, Jennifer Boldt, Devin Brewer, Roberto Lopez, Brian Whipker

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Characteristics of tongue images and tongue coating bacteria in patients with colorectal cancer by Wu Zheng, Wu Yinhang, Chu Jian, Jin Congjian, Qu Zhanbo, Jean-Marie Nianga, Louis Wang, Wang Zefeng, Huang Jiaqun, Yu Xiaojian, Yang Shujing, Duan Jinlong, Liu Jiang, Han Shuwen

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Disentangling the gut microbiota of Aldabra giant tortoises of different ages and environments by Douaa Zakaria, Camillo Sandri, Monica Modesto, Caterina Spiezio, Donatella Scarafile, Allen Cedras, Luigimaria Borruso, Paolo Manghi, Paolo Trevisi, Nicola Segata, Paola Mattarelli, Masanori Arita

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