Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial by Ingrid Muller, Miriam Santer, Beth Stuart, Paul Little, Matthew J Ridd, Karen Thomas, Nick Francis, Kim S Thomas, Gareth Griffiths, Natalia V Permyakova, Jacqui Nuttall, Irene Soulsby, Alison M Layton, Tracey H Sach, Sarah Pyne, Susanne Renz, Zina Eminton, Megan Lawrence

“…Adjusted analysis included randomisation stratification variables (centre, baseline severity (investigator’s global assessment, IGA <3 vs ≥3)) and baseline variables (Acne-QoL symptom subscale score, resource use costs, EQ-5D score and use of topical treatments).Results Spironolactone did not appear cost-effective in the complete case analysis (n=126 spironolactone, n=109 control), compared with no active systemic treatment (adjusted incremental cost per QALY £67 191; unadjusted £34 770). …”
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Health literacy disparities in South Korea: insights from a latent profile analysis by Sunghyun Kim, Suwon Hwang, Junhyup Lee, Mankyu Choi

“…Existing interventions generally employ a variable-centred approach, often neglecting the cumulative impact of various factors and the ways different groups interact with health information. …”
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Interconnectivity among different nonsuicidal self-injurious methods – a network analysis by Melinda Reinhardt, Kenneth G. Rice, Hunggu Cho, Zsolt Horváth

“…In contrast to person-centred approaches, variable-centred network analysis helps to identify the most meaningful associations between different forms of NSSI behavior, thus allowing the identification of structural patterns in different NSSI methods. …”
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