Multiple mush generations provide insight into the longevity of open-conduit basaltic volcanoes by Beatrice Schiavon, Chiara M. Petrone, Francesca Forni, Alessio Pontesilli, Haiyang Hu, Piergiorgio Scarlato, Daniele Andronico, Elisabetta Del Bello, Manuela Nazzari, Silvio Mollo

“…The complex zoning patterns of plagioclase phenocrysts from 2003 to 2021 eruptions have been interrogated by combining in-situ Sr isotope compositions, thermometric modelling, and Mg diffusion chronometry. …”
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Evaluation of Internal Adaptation of Different CAD/CAM Endocrown Materials: A Comparative Microcomputed Tomography Study by Wala Saad, Abdul Rahman Saleh, Manal Almaslamani

“…Methods: Standardized endocrown restorations were fabricated for mandibular first molar models. A total of seventy-five restorations were evenly allocated into five groups (n = 15 each): Group I (Cerec Blocks), Group II (Lava Ultimate), Group III (PICN Vita Enamic), Group IV (Celtra Duo), and Group V (Cerec Tessera). …”
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Investigating the relationship between thought interference, somatic passivity and outcomes in patients with psychosis: a natural language processing approach using a clinical reco... by Robert Stewart, Anna Kolliakou, Jyoti Sanyal, Rashmi Patel, Thibault Thierry Magrangeas

“…Objectives We aimed to apply natural language processing algorithms in routine healthcare records to identify reported somatic passivity (external control of sensations, actions and impulses) and thought interference symptoms (thought broadcasting, insertion, withdrawal), first-rank symptoms traditionally central to diagnosing schizophrenia, and determine associations with prognosis by analysing routine outcomes.Design Four algorithms were developed on deidentified mental healthcare data and applied to ascertain recorded symptoms over the 3 months following first presentation to a mental healthcare provider in a cohort of patients with a primary schizophreniform disorder (ICD-10 F20-F29) diagnosis.Setting and participants From the electronic health records of a large secondary mental healthcare provider in south London, 9323 patients were ascertained from 2007 to the data extraction date (25 February 2020).Outcomes The primary binary dependent variable for logistic regression analyses was any negative outcome (Mental Health Act section, >2 antipsychotics prescribed, >22 days spent in crisis care) over the subsequent 2 years.Results Final adjusted models indicated significant associations of this composite outcome with baseline somatic passivity (prevalence 4.9%; adjusted OR 1.61, 95% CI 1.37 to 1.88), thought insertion (10.7%; 1.24, 95% CI 1.15 to 1.55) and thought withdrawal (4.9%; 1.36, 95% CI 1.10 to 1.69), but not independently with thought broadcast (10.3%; 1.05, 95% CI 0.91 to 1.22).Conclusions Symptoms traditionally central to the diagnosis of schizophrenia, but under-represented in current diagnostic frameworks, were thus identified as important predictors of short-term to medium-term prognosis in schizophreniform disorders.…”
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A Causal Inference Approach to Mediation Analysis in Vitreomacular Traction: How Much Does Traction Resolution Mediate Functional Outcomes? by Benedicte Lescrauwaet, Stijn Vansteelandt, Timothy L. Jackson, SriniVas R. Sadda, Luc Duchateau

“…A causal mediation analysis is applied to randomized trial data including 218 participants with vitreomacular traction. Logistic regression models are used to estimate the total treatment effect (TTE) on binary outcomes. …”
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Determinants of improvement trends in health workers' compliance with outpatient malaria case-management guidelines at health facilities with available "test and treat" commodities... by Beatrice Amboko, Kasia Stepniewska, Lucas Malla, Beatrice Machini, Philip Bejon, Robert W Snow, Dejan Zurovac

“…Association between 31 determinants and improvement trends in five outpatient compliance outcomes were examined using interactions between each determinant and time in multilevel logistic regression models and reported as an adjusted odds ratio of annual trends (T-aOR).…”
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Assessing the determinants associated with fidelity to the 2016 world health organization antenatal care policy across states in Nigeria by Christiana Ikemeh, Adedayo O. Adeyemi, Leah M. Frerichs, Christopher M. Shea, Justin G. Trogdon

“…Fidelity was measured as the proportion of women who cumulatively adhered to five selected ANC components—timing of first ANC visit, blood pressure measurement, tetanus vaccinations, urinalysis, and blood sample test. A binary outcome variable was generated as a fidelity index by creating a composite score from all the measures of the five components, which was categorized as ‘concordant’ and ‘partial/non-concordant’. …”
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Impact of healthy pregnancy and lifestyle in mothers on developmental delay in their offspring: a strength-based analysis of a longitudinal study among indigenous children in Austr... by Md Irteja Islam, Thomas Stubbs, Tuguy Esgin, Alexandra Martiniuk

“…A composite score (ranging from 0 to 3, score = 3 refers to most healthy pregnancy) was created for a healthy pregnancy and lifestyle variable using three criteria − (1) a lack of medical conditions, (2) no substance use including smoking/alcohol/illicit drugs, and (3) intake of iron/folic acid during pregnancy. …”
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Gut microbiome predictors of advanced therapy response in Crohn’s disease: protocol for the OPTIMIST prospective, longitudinal, observational pilot study in Canada by Greg Rosenfeld, Susanna Meade, Yvette Leung, Astrid-Jane Williams, Gurpreet Kaur, Brian Bressler, Cristian Aldo Massaro, Fanny Laure Lemarié, Genelle Lunken

“…Despite advancements in treatment, such as biologics, response rates remain variable, highlighting the need for personalised approaches. …”
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Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia by Sol Kim, Yumi Seo, Moon-Yeon Oh, Min Soo Kim, Sook Kyung Yum

“…<b>Objectives</b>: Pulmonary hypertension and hemodynamically significant PDA (hsPDA) involve seemingly opposite physiological features—decreased pulmonary blood flow and pulmonary overcirculation, respectively—but the literature demonstrates variable respiratory consequences in association with each of these morbidities. …”
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Association between energy intake and prognosis in Chronic Kidney Disease (CKD) stages 3–5: an ambispective cohort study by Di Yang, Huifen Chen, Yan Han, Yuhan Shen, Guixin Liang, Tao Zhou, Fang Tang, Lizhe Fu, Yifan Wu, Meizhu Ding

“…The main variable was energy intake. Kaplan–Meier analysis, restricted cubic splines, and Cox regression models were performed to assess the association.Results 85 (36.3%) individuals reached the endpoint with a median follow-up of 33 months. …”
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The association between age and long-term quality of life after curative treatment for prostate cancer: a cross-sectional study by Reidun Sletten, Ola Berger Christiansen, Line Merethe Oldervoll, Lennart Åstrøm, Håvard Kjesbu Skjellegrind, Jūratė Šaltytė Benth, Øyvind Kirkevold, Sverre Bergh, Bjørn Henning Grønberg, Siri Rostoft, Asta Bye, Paul Jarle Mork, Marit Slaaen

“…Global QoL and PF were assessed by the European Organisation of Research and Treatment in Cancer Quality of life Questionnaire-C30 (QLQ-C30), side effects by the Expanded Prostate Cancer Index Composite (EPIC-26). Adjusted linear regression models were estimated to assess associations between age (continuous variable) at treatment and outcomes. …”
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Remnant–to–LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project... by Eva Soler-Espejo, Yang Chen, José Miguel Rivera-Caravaca, María Pilar Ramos-Bratos, Raquel López-Gálvez, Francisco Marín, Vanessa Roldán, Gregory Y.H. Lip

“…Associations between RC levels and clinical outcomes across LDL-C strata were assessed using multivariable Cox proportional hazards models and as a continuous variable using restricted cubic spline (RCS) analyses. …”
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Predicting neurodevelopmental outcomes from neonatal cortical microstructure: A conceptual replication study by Andrea Gondová, Sara Neumane, Yann Leprince, Jean-François Mangin, Tomoki Arichi, Jessica Dubois

“…This allowed us to evaluate whether some limitations of the original study (mainly small sample size and limited variability in the input and output features used in the predictive models) would influence the prediction results. …”
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CPFD Simulation of Operation Characteristics of a 10t/d Sludge and Biomass Co-incineration Fluidized Bed Reactor by REN Shaohui, YU Qiao, LIN Li, XIANG Jiatao, MA Lun, ZHANG Shihong

“…ObjectiveThis research aims to comprehensively investigate the operational dynamics of a 10t/d sludge and biomass co-incineration fluidized bed reactor through Computational Particle Fluid Dynamics (CPFD) modeling, addressing critical gaps in industrial-scale waste valorization. …”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…This study used the TMB algorithm from the FDA-approved test supporting solid tumor CDx and composite mortality variable validated against the national death index: real-world overall survival (rwOS). …”
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Direct measurement of N₂O₅ heterogeneous uptake coefficients on atmospheric aerosols in southwestern China and evaluation of current parameterizations by J. Li, T. Zhai, T. Zhai, X. Chen, H. Wang, S. Xie, S. Chen, C. Li, C. Li, Y. Gong, H. Dong, K. Lu

“…We found that several parameterizations can capture the median of measured values, whereas none of the 10 parameterizations were able to reproduce the variabilities and showed poor correlations (<span class="inline-formula"><i>R</i>²=0.00</span>–0.09). …”
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