Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. by Maila Giannandrea, Fabrizia C Guarnieri, Niels H Gehring, Elena Monzani, Fabio Benfenati, Andreas E Kulozik, Flavia Valtorta

“…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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Internal Benchmarking of Thermal Power Plants оf Electric Power Systems by E. M. Farhadzadeh, A. Z. Muradaliyev, Y. Z. Farzaliyev, U. K. Ashurova

“…A necessary condition for the feasibility of using these or those integral indicators is their functional and statistical independence. The results of the studies performed using the simulation method made it possible to establish that the smallest correlation occurs between the integral indicator calculated as the arithmetic mean of random variables and the integral indicator calculated as the coefficient of variation of the same random variables. …”
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STRUCTURAL RELIABILITY OPTIMIZATION DESIGN OF REINFORCED SHELL MODEL BASED ON ADAPTIVE SURROGATE MODEL by LIU YuZhuo, CAO LiXiong, WU JianGuo, LI HaiBo

“…Reinforced shell structure is widely used in aerospace load-bearing structures because its high specific stiffness and specific strength.By considering the uncertainty and risk factors in the structural parameters，the Reliability-Based Design Optimization （RBDO） can avoid the overly conservative design of the structure and ensure its reliability and safety.An efficient RBDO method based on adaptive agent model was proposed.This method solves the problem of lightweight design of reinforced shell structure under buckling reliability constraints.The adaptive addition of sample points was implemented through the expected feasibility function criterion，and the discrete variables was continued by constructing piecewise functions.This increases optimization efficiency while ensuring the reliability of design results.Finally，the effectiveness of the proposed method is verified by comparing the RBDO results with the deterministic optimization results.…”
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Methodology for assessing the spherical plain bearings durability by V. K. Harina, O. A. Ratenko, G. B. Vardanyan

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Natural assets, changes, and variations of the socioeconomic-environmental systems along the Asian drylands belt by Jiquan Chen, Ranjeet John, Venkatesh Kolluru, Elizabeth A Mack, Peilei Fan, Jing Yuan, Zutao Ouyang, Jingyan Chen, Pavel Groisman, Changliang Shao, Amarjargal Amartuvshin, Garik Gutman

“…We found increased variability as well as spikes in extreme values in each of these three measures of SES function among the 23 PEs over the study period. …”
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West Nile Virus Vaccine Design by T Cell Epitope Selection: In Silico Analysis of Conservation, Functional Cross-Reactivity with the Human Genome, and Population Coverage by Frances M. Waller, Pedro A. Reche, Darren R. Flower

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Eficiência técnica na suinocultura: efeitos dos gastos com meio ambiente e da renúncia fiscal Technical efficiency in swine breeding: effect of the expenses with the environment an... by Benedito D. Pereira, João C. de S. Maia, Rosalina Camilot

“…After estimating the technical efficiency indices with data of ten properties situated in Mato Grosso from production functions, whose dependent variable is represented by the production of swine and the independent ones are the consumption of water, electricity and the amount of workers directly tied with the productive process. …”
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Study on Operation Control Strategy for Campus Public Building Heating Systems in Severe Cold Areas by Chuntian Lu, Shourui Xue, Yuetong Zhang, Songqing Wang

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Impacts of high viscosity variation and internal heating on mantle convection in different aspect ratio cells by Tania S. Khaleque, Md. Shafiul A. Khan, Romana Yesmin

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Improving the Dynamics of an Electrical Drive Using a Modified Controller Structure Accompanied by Delayed Inputs by Konrad Urbanski, Dariusz Janiszewski

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THE COMPUTER-AIDED CONTROLLING OF TECHNICAL AND TECHNOLOGICAL PLANTS IN THE WAVELET MEDIUM by Fedosenkov D.B., Tokarev S.V., Simikova A.A., Iskhakov R.R., Fedosenkov B.A.

“…Methods of formalizing material flows created in certain knots of structure-and-functional diagram of the mixture producing aggregate are considered, that are founded on transforming one-dimensional initial flow signals into multi-dimensional ones. …”
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Vehicle detection method based on multi-layer selective feature for UAV aerial images by Yinbao Ma, Yuyu Meng, Jiuyuan Huo

“…However, this task remains challenging due to variable high-altitude viewpoints, complex environmental interference, and limitations in algorithmic efficiency. …”
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Multiobjective optimization of Murta (Ugni molinae Turcz) juice lactic acid fermentation with monocultures and cocultures of Lactobacillus acidophilus and Lactiplantibacillus plant... by C.J. Gomes-Lobo, R. Luna, A. Rodríguez-Machado, J.R. Pérez-Correa, W. Franco

“…These findings highlight the practical utility of MOO-MCDM for designing efficient multiobjective fermentation processes in functional food development.…”
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Artificial intelligence-driven fuzzy logic approach for optimal well selection in gas lift design: A brown field case study by Nnaemeka Princewill Ohia, Chadi Paul, Emmanuel Asolo, Taiwo Adetomiwa Adewa, Chidimma Favour Chukwu, Paschal Ateb Ubi, Daniel Hogan Itam, Daniel Ugochukwu Nnaji

“…However, selecting suitable wells for gas lift is complex due to the inherent uncertainty and variability in petroleum production data. Traditional decision-making approaches often struggle with this uncertainty, leading to suboptimal choices that can reduce efficiency and increase operational costs. …”
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Community re-entry program on global functioning and medication adherence among bipolar affective disorder patients- A randomized controlled trial pilot study by Jaishri, Sreevani Rentala, Preethy Kathiresan, Mukesh Swami

“…This quantitative study to explores the effectiveness of community re-entry program on global functioning and medication adherence for patients with bipolar affective disorder. …”
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Optimization of urban spatial planning considering isochrones of transport accessibility: The case of Aktobe city, Kazakhstan by Aigul Sergeyeva, Imanaly Akbar, Yergali Karakulov

“…Urban areas are characterized by diversity and variability, depending on their size, function, combination of elements, and the spatial distribution of industrial and transport infrastructure. …”
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Identification of quality problems staff vocational training by Vera V. Zhivaeva, Vadim A. Nikovaev, Svetlana N. Parfenova, Elena P. Tuponosova

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Carpal tunnel release surgery restores force control but not force coordination in CTS patients by Thomas Jacob, Mohamed Ibrahim, G. Vishnu Babu, K. Shyamnath Krishna Pandian, R. Krishnamoorthy, G. Karthikeyan, P. Jeyakumar, V. S. Valarmathy, Jahir Hussain, C. S. Ezhilavan, K. Sridhar, Sivakumar Balasubramanian, S. K. M. Varadhan

“…Abstract Efficient manipulation of objects is crucial for daily interactions with the world. …”
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Development and evaluation of the organization`s logistics strategy based on the application of bifurcation theory by M. Yu. Uchirova, L. A. Ilin, S. V. Khudyakov

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Structural Damage Identification Using PID-Based Search Algorithm: A Control-Theory Inspired Application by Kuang Shi, Tingting Sun

“…We developed finite element programs for a 10-element simply supported beam, a 21-element truss, and a 7-story steel frame, assigning damage factors to each element as design variables. The Relative Frequency Change Rate (RFCR) and Modal Assurance Criterion (MAC) were calculated as objective functions for PSA iteration; comparative studies were then conducted against Particle Swarm Optimization (PSO), Genetic Algorithm (GA), and Simulated Annealing (SA) in terms of damage identification accuracy, computational efficiency, and noise robustness. …”
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