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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries
Published 2025-07-01“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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1342
Harnessing biostimulants for sustainable agriculture: innovations, challenges, and future prospects
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1343
Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy.
Published 2012-01-01“…Variable polyA(n) length was confirmed in DNA from different RPGRIP1(-/-) dogs, yet polyA(n) variability did not correspond with the clinical phenotypes and no individual was found that carried a polyA(n) tract capable of encoding an in-frame variant. …”
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1344
Concomitant generation of hydrogen during carbon dioxide storage in ultramafic massifs- state of the art with implications to decarbonization strategies
Published 2025-09-01“…Mineral trapping of CO₂ recently emerged as one of the most efficient and lowest-risk approaches for long-term CO₂ sequestration. …”
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1345
Acute Effects of Two Different Species of Amyloid-β on Oscillatory Activity and Synaptic Plasticity in the Commissural CA3-CA1 Circuit of the Hippocampus
Published 2020-01-01“…Soluble Aβ microinjection increased cCA3-to-CA1 synaptic variability without significant changes in synaptic efficiency. …”
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1346
The Impact of Corporate Governance on Earnings Management in Palestine: The Moderating Effects of Political Instability
Published 2021-04-01“…The results of this work may assist the regulatory bodies, policymakers, and practitioners in revising the corporate governance code to promote the efficiency of the BOD and AC monitoring functions for the purpose to improve the faithfulness and reliability of financial reports and also to deter the management from engaging in critical levels of EM.…”
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1347
Histological and molecular characterization of the digestive system of early weaned juveniles of Arapaima sp. reared in a recirculating aquaculture system.
Published 2025-01-01“…However, reliance on natural breeding and parental care in earthen ponds results in variable fingerling survival, hindering production. …”
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1348
Geospatial Multi-User Channel Condition Interpolation for Instantaneous Sporadic Transmission and CSI Feedback Overhead Reduction in 5G and Beyond
Published 2024-01-01“…Next-generation networks look for innovative solutions to enable new service functionalities while increasing the system efficiency. …”
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1349
Surrogate modeling of passive microwave circuits using recurrent neural networks and domain confinement
Published 2025-04-01“…Utilization of frequency as a sequential variable handled by RNN is a distinguishing feature of our approach, which leads to the enhancement of dependability and cost efficiency. …”
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1350
MODELING THE IMPACT OF THE TRANSPORT PROVISION OPTION ON PROJECT RISKS
Published 2020-12-01“…The aim of the study is to improve the efficiency of project management processes by identifying and formalizing the risks associated with the transportation of the project. …”
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1351
Predicting Wastewater Characteristics Using Artificial Neural Network and Machine Learning Methods for Enhanced Operation of Oxidation Ditch
Published 2025-01-01“…This study investigates the operational efficiency of the lab-scale oxidation ditch (OD) functioning in simultaneous nitrification and denitrification modes, focusing on forecasting biochemical oxygen demand (BOD<sub>5</sub>) concentrations over a five-day horizon. …”
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1352
Sustainable extraction of bioproducts from cactus pear waste: Economic viability and market opportunities in a green economy
Published 2025-01-01“…Further research should explore alternative biomass sources and innovations in extraction efficiency to ensure continuous production and cost reductions.…”
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1353
Assessing motor control and movement quality in patients with non-specific low back pain: a scoping review and development of an ICF-based conceptual framework
Published 2025-06-01“…A conceptual framework was constructed, consisting of five International Classification of Functioning, Disability and Health-based broad motor control functions and 10 movement quality domains, namely flexibility, stability, accuracy, symmetry, speed, smoothness, adaptability, variability, efficiency and coordination.Conclusion The provided conceptual framework for motor control functions and movement quality domains can serve as a structural foundation for future research on the content validity of assessment approaches in the context of LBP.…”
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1354
Spatiotemporal changes of ecosystem health and the impact of its driving factors on the Loess Plateau in China
Published 2025-01-01“…Based on this idea, a new framework for assessing EH is proposed. The efficient machine learning model (light gradient boosting machine model) and the variable explanation model (SHapley Additive exPlanation model) are combined to quantify the functional relationships between various driving factors and EH, thereby exploring the impacts of climatic factors, socioeconomic development (SED), and ecological restoration projects (ERP) on EH. …”
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1355
Cumulative Distribution-Based Method for Pavement Performance Modeling
Published 2024-06-01“…Predicting future pavement conditions accurately and efficiently helps determine the optimal maintenance time, select appropriate measures, and allocate rehabilitation funds effectively. …”
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1356
Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy
Published 2025-05-01“…The cells were pre-stimulated through CD3/CD28 beads before lentiviral transduction. Transduction efficiency, fold expansion and phenotype were monitored for the CAR T cells expanded for 10–12 days. …”
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1357
Bottom-up Biomaterial strategies for creating tailored stem cells in regenerative medicine
Published 2025-05-01“…By replicating lineage-specific mechanical, chemical, and spatial cues, these tailored biomaterials enhance differentiation fidelity, reprogramming efficiency, and functional integration. This paradigm shift from passive scaffolds to dynamic, cell-instructive platforms bridges critical gaps between laboratory success and clinical translation, offering a transformative roadmap for regenerative medicine and tissue engineering.…”
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1358
Elucidating the role of mind–body connection profiles in emotional reactivity and regulation amongst typically developed adults
Published 2025-08-01“…Abstract Background Adaptive emotional functioning necessitates a strong mind–body connection. …”
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1359
Identifying confounders and estimating the causal effect of antenatal care on age-specific childhood vaccination
Published 2025-05-01“…BackgroundImmunization is an efficient and cost-effective public health program. …”
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1360
Optimized Temporal Interference Stimulation Based on Convex Optimization: A Computational Study
Published 2025-01-01“…CVXTI leverages the distribution characteristics of the TI envelope electric field to optimize electrode configurations, enhancing the optimization efficiency.…”
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