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Binding patterns of glycine receptor autoantibodies are related to clinical syndromes
Published 2025-07-01“…Even if variations between labeled areas and cell layers were rather patient-specific than group-specific, functionality of the labeled areas aligned with the patients’ impaired functions. …”
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Bioprinting for drug screening: A path toward reducing animal testing or redefining preclinical research?
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Design and Detection Performance of Metal Contaminant Sensor with Triple Coil Structure
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Refinement of the phase diagram of the MnSe–In2Se3 system and the crystal structures of MnIn2Se4 and Mn2In2Se5 compounds
Published 2025-03-01“…Complex chalcogenides based on transition elements, in particular ternary compounds of the АВ2Х4 type (M = Mn, Fe, Co, Ni; B = Ga, In, Sb, Bi; X = S, Se, Te) are among the important functional materials. …”
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Characterization and clustering of intra-day physical activity patterns using accelerometry among sexual and gender minority adults
Published 2025-07-01“…., clusters) of daily PA trajectories among sexual and gender minority (SGM; lesbian, gay, bisexual, transgender, queer) adults using functional latent block models (FLBMs), a co-clustering technique that simultaneously accounts for variation at the individual- and day-level. …”
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In vivo programmed myeloid cells expressing novel chimeric antigen receptors show potent anti-tumor activity in preclinical solid tumor models
Published 2024-12-01“…The mRNA encoding the TROP2 CAR was encapsulated in LNPs. Co-immunoprecipitation, flow cytometry and enzyme-linked immunosorbent assay (ELISA) were used to measure CAR expression and functional activity in vitro. …”
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The gene regulatory mechanisms shaping the heterogeneity of venom production in the Cape coral snake
Published 2025-05-01“…Within these venom systems, the molecular, cellular, and morphological components interact and co-evolve to generate distinct, venom phenotypes that are increasingly recognized as models for studying adaptive evolution. …”
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Single and multi-omic characterization of a porcine model of ethanol-induced hepatic fibrosis
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Marine environmental monitoring programmes in South Africa: a review
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A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected].
Published 2014-05-01“…We show that the null phenotype is rescued more effectively by an Lmx1b transgene than is Icst. Co-immunoprecipitation experiments show that both wild-type and Icst LMX1B are found in complexes with LIM domain binding protein 1 (LDB1), resulting in lower levels of functional LMX1B in Icst heterozygotes than null heterozygotes. …”
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High performance of a low input, mixed western Australian farming system: public policy implications from the case of Tolga farm
Published 2023-11-01“…The business has steadily grown over the past 30 years. Emissions (T/CO2e/ha) are estimated to be low compared to industry benchmarks and evidence exists that the farm’s total organic carbon pool is either reflective of or is as much as 40% higher than the surrounding area.…”
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Local structural distortions drive magnetic molecular field in compositionally complex spinel oxide
Published 2025-07-01“…We address this for a compositionally complex spinel oxide (Mn0.2Co0.2Ni0.2Cu0.2Zn0.2)Cr2O4 (A 5Cr2O4). By comparatively examining extended X-ray absorption fine structure on A 5Cr2O4 and its parent counterparts, ACr2O4, along with density functional theory calculations for multiple configurations, we find that the element-specific distortions go beyond the first neighbor. …”
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An investigation into possible interactions in the vestibular system and the cochlea during electrical stimulation
Published 2025-05-01“…Bilateral vestibulopathy (BV) severely impairs these functions, often co-occurring with severe to profound hearing loss. …”
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FAT1-weighted MRI-guided focused ultrasound thalamotomy for essential tremor
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Identification and characterization of the GH3 gene family in maize
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Enterotype-stratified gut microbial signatures in MASLD and cirrhosis based on integrated microbiome data
Published 2025-05-01“…Enterotype classification was performed using principal component analysis, with advanced bioinformatics tools, including Linear Discriminant Analysis Effect Size (LEfSe), eXtreme Gradient Boosting (XGBoost), and Deep Cross-Fusion Networks for Genome-Scale Identification of Pathogens (DCiPatho), to identify differentially abundant microbes and potential pathogens. Microbial co-occurrence networks and functional predictions via PICRUSt2 revealed distinct patterns across enterotypes.Results and discussionThe Prevotella-dominated(ET-P) group exhibited a 33% higher cirrhosis rate than the Bacteroides-dominated(ET-B) group. …”
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