Suggested Topics within your search.
Suggested Topics within your search.
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Insight into the Microbiota of Orthopteran in Relation to Gut Compartmentalisation
Published 2025-05-01“…This review first provides an overview of the functional diversity of Orthoptera-associated microbiota and the services they provide to their hosts. …”
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Effects of Microplastics, Fertilization and Pesticides on Alien and Native Plants
Published 2024-10-01“…Here, five aliens and co-occurring natives were selected as study materials, and a full factorial experiment was conducted to answer this question. …”
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A case of glial fibrillary acidotic protein (GFAP) meningoencephalitis with rheumatoid arthritis
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The allelic rice immune receptor Pikh confers extended resistance to strains of the blast fungus through a single polymorphism in the effector binding interface.
Published 2021-03-01“…Arms race co-evolution drives rapid adaptive changes in pathogens and in the immune systems of their hosts. …”
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TwinCons: Conservation score for uncovering deep sequence similarity and divergence.
Published 2021-10-01“…The output distinguishes conserved, variable and signature positions. A signature is conserved within groups but differs between groups. …”
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Integrating single-cell and bulk RNA profiles to uncover glutamine metabolism’s role in prognosis and immune dynamics in multiple myeloma
Published 2025-05-01“…Abstract Objective Multiple myeloma (MM) exhibits significant heterogeneity, leading to variable treatment responses and poor clinical outcomes. …”
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Landscape and variation of novel retroduplications in 26 human populations.
Published 2017-06-01“…We also found retroduplications to be associated with a variety of genomic features: (1) Insertion sites were correlated with regular nucleosome positioning. (2) They, predictably, tend to avoid conserved functional regions, such as exons, but, somewhat surprisingly, also avoid introns. (3) Retroduplications tend to be co-inserted with young L1 elements, indicating recent retrotranspositional activity, and (4) they have a weak tendency to originate from highly expressed parent genes. …”
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Nanodesigner: resolving the complex-CDR interdependency with iterative refinement
Published 2025-08-01“…Abstract Camelid heavy-chain only antibodies consist of two heavy chains and single variable domains (VHHs), which retain antigen-binding functionality even when isolated. …”
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A versatile genetic toolkit for engineering Wickerhamomyces ciferrii for tetraacetyl phytosphingosine production
Published 2025-04-01“…To demonstrate the functional application of this toolkit, we overexpressed a phosphorylation-insensitive mutant of acetyl-CoA carboxylase (ACC1S26A-S1161A), resulting in a 2.4-fold increase in TAPS production. …”
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Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy
Published 2025-01-01“…Abstract α-Klotho (KLA) is a type-1 membranous protein that can associate with fibroblast growth factor receptor (FGFR) to form co-receptor for FGF23. The ectodomain of unassociated KLA is shed as soluble KLA (sKLA) to exert FGFR/FGF23-independent pleiotropic functions. …”
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Thioredoxin regulates T cell proliferation and aggravates the severity of influenza a virus infection
Published 2025-07-01“…From these data, we identified 10 key differential genes through a combination of differential analysis, WGCNA, and Friends analysis and further identified that only TXN and S100A6 co-existed in the highly variable genes of proliferative T cells. …”
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Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Published 2007-07-01“…In a bladder cell culture system, beta1 and alpha3 integrin receptors co-localize with invading type 1-piliated bacteria and F-actin. …”
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Body Temperature Differences Between Green And Brown Grasshoppers Do Not Result From Thermal Physiology or Thermal Preferences
Published 2025-03-01“…ABSTRACT Colour polymorphisms correspond to the co‐occurrence of several distinct colour morphs that vary in hue and/or brightness, independently of sex, age or any other state‐dependent modifiers. …”
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Protein epigenetic scores and overall mortality in the longitudinal Swedish Adoption/Twin Study of Aging (SATSA)
Published 2025-03-01“…Abstract Introduction DNA methylation (DNAm) has a functional role in gene regulation, and it has been used to estimate various human characteristics. …”
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