Effects of a Digital Functional Exercise Program on the Disease Activities and Physical Capabilities of Patients With Ankylosing Spondylitis: Protocol for a Randomized Controlled T... by Xingkang Liu, Xiaojian Ji, Lidong Hu, Tianyu Jiang, Ang Min, Lulu Zeng, Yiwen Wang, Meihui Zhao, Jian Zhu, Feng Huang, Changshui Weng, Zheng Zhao

“… BackgroundAnkylosing spondylitis (AS), a chronic inflammatory disease, causes spinal stiffness, functional impairment, and reduced quality of life. …”
Get full text

Heterotypic spheroids as a strategy for 3D culture of cryopreserved primary human hepatocytes in stirred-tank systems by Francisca Arez, Lena Preiss, Isabella Ramella Gal, Sofia P. Rebelo, Lassina Badolo, Catarina Brito, Thomas Spangenberg, Paula M. Alves

“…Primary human hepatocytes (PHHs) are the preferred cell source to address liver function. Despite originating from the native tissue, one of the bottlenecks when using primary material is the donor-to-donor variability. …”
Get full text

Cognitive and affective theory-of-mind impairment in people with early-stage bipolar disorder by Jacob Man Tik Chan, Heidi Ka Ying Lo, Anson Kai Chun Chau, Aerin Sum Yin Mok, Co Co Ho Yi Tong, Candice Tze Kwan Kam, Catherine Zhiqian Fang, Wing Chung Chang

Get full text

Neurobiomechanical Characterization of Feedforward Phase of Gait Initiation in Chronic Stroke: A Linear and Non-Linear Approach by Marta Freitas, Pedro Fonseca, Leonel Alves, Liliana Pinho, Sandra Silva, Vânia Figueira, José Félix, Francisco Pinho, João Paulo Vilas-Boas, Augusta Silva

“…Ground reaction forces were measured via force plates (Bertec, Columbus, OH, USA) to compute CoP variables. Linear (displacement, amplitude, and velocity) and non-linear (Lyapunov exponent—LyE and multiscale entropy—MSE) measures were applied to assess postural control complexity and variability. …”
Get full text

Impaired physical function in relation to later-life exposure to ambient fine particulate matter and ozone among Chinese middle-aged and older adults by Yuxi Tan, Qianqian Xiang, Yalin Zhang, Jiajun Shen, Minjin Peng, Xiaojie Sun, Ting Cai, Yunquan Zhang

“…Stratified analyses for co-pollutants indicated weakened effects of PM2.5 and O3 at higher co-pollutant levels (PM2.5: −0.448 [−0.522, −0.373]; O3: −0.796 [−1.070, −0.522]) than at lower levels (PM2.5: −0.608 [−0.708, −0.507]; O3: −1.293 [−1.612, −0.974]). …”
Get full text

Growth, physical, and cognitive function in children who are born HIV-free: School-age follow-up of a cluster-randomised trial in rural Zimbabwe. by Joe D Piper, Clever Mazhanga, Marian Mwapaura, Gloria Mapako, Idah Mapurisa, Tsitsi Mashedze, Eunice Munyama, Maria Kuona, Thombizodwa Mashiri, Kundai Sibanda, Dzidzai Matemavi, Monica Tichagwa, Soneni Nyoni, Asinje Saidi, Manasa Mangwende, Dzivaidzo Chidhanguro, Eddington Mpofu, Joice Tome, Gabriel Mbewe, Batsirai Mutasa, Bernard Chasekwa, Handrea Njovo, Chandiwana Nyachowe, Mary Muchekeza, Kuda Mutasa, Virginia Sauramba, Ceri Evans, Melissa J Gladstone, Jonathan C Wells, Elizabeth Allen, Melanie Smuk, Jean H Humphrey, Lisa F Langhaug, Naume V Tavengwa, Robert Ntozini, Andrew J Prendergast

“…We found strong evidence that cognitive function was lower in CBHF compared to CHU across multiple domains. …”
Get full text

Geometric structure of parameter space in immiscible two-phase flow in porous media by Håkon Pedersen, Alex Hansen

“…In assuming Euler homogeneity of the total volumetric flow rate and comparing the resulting first-order partial differential equation to the total volumetric flow rate in the porous medium, one can introduce a novel velocity that relates the two pairs of velocities. This velocity, the co-moving velocity, describes the mutual co-carrying of fluids due to immiscibility effects and interactions between the fluid clusters and the porous medium itself. …”
Get full text

Platform Technology for Extended Reality Biofeedback Training Under Operant Conditioning for Functional Limb Weakness: Protocol for the Coproduction of an at-Home Solution (React2H... by Anirban Dutta, Abhijit Das

“…Approaches such as experience-based co-design and quality function deployment can support coproduction by systematically addressing usability and accessibility challenges. …”
Get full text

Adaptive coordinated control for an under-actuated airplane–tractor system with parameter uncertainties by Pengjie Xu, Weining Huang, Tianrui Zhao, Wei Zhang, Tongwei Lu, Guiyan Qiang, Lin Zhang, Yanzheng Zhao

“…Next, an adaptive control structure is introduced to handle system parameters uncertainties via the unconstrained variable. Co-simulations and a real experiment are conducted in the end. …”
Get full text

Study on the Stirring Device of Vinyl Polymers by Zhiqiang ZHU, Fanglin JIANG, Yangyong MAO, Jianfeng WU, Qingwei JIANG, Sujie JIANG

Get full text

Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

Get full text

Drivers of toxic element accumulation in terrestrial ecosystems across elevational gradients by Baba Imoro Musah, Jie Yang, Guorui Xu

“…It also lays the groundwork for further study on how toxic elements impact ecosystem functions, which is crucial for protecting biodiversity under climate change.…”
Get full text

Validation of an interferon-gamma enzyme-linked immunosorbent spot assay to evaluate cell-mediated immunity against severe acute respiratory syndrome coronavirus 2 by Yunhwa Kim, Eun-Jeong Jang, Ji-Young Hwang, Kyung-Min Lee, Sivilay Xayaheuang, Seok-Tae Choi, Hosun Park

“…Taken together, we demonstrated that the IFN-γ ELISpot assay is feasible for evaluating SARS-CoV-2-specific cell-mediated immune function through validation based on standard operating procedures.…”
Get full text

Evaluating the Effectiveness of Natural Carbon Sinks Through a Temperature-Dependent Model by Joachim Dengler

“…Articles have recently been circulating in the media around the world, claiming that natural <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>CO</mi><mn>2</mn></msub></mrow></semantics></math></inline-formula> sinks have “suddenly and unexpectedly” ceased to function. …”
Get full text

Revealing the mechanisms and therapeutic potential of immune checkpoint proteins across diverse protein families by Ran Liu, Xinyan Jiang, Ruijuan Dong, Yuting Zhang, Cong Gai, Peng Wei

“…In this review, we discuss the current understanding of the mechanisms underlying the co-suppressive functions of CTLA-4, PD-1, and other prominent immune checkpoint pathways. …”
Get full text

The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change by Yuhang Li, Yujie Yan, Haojie Wu, Yiyi Men, Yi Yang, Hengguang Fu, Derek Dunn, Xiaowei Wang, Genggeng Gao, Peng Zhang, Guixin Dong, Liyuan Hao, Jia Jia, Baoguo Li, Songtao Guo

Get full text

Nonlinear forecasting of stream flows using a chaotic approach and artificial neural networks by Hakan Tongal

Get full text

Concomitant generation of hydrogen during carbon dioxide storage in ultramafic massifs- state of the art with implications to decarbonization strategies by Mahmoud Leila, Randy Hazlett, Paul Mathews George, Isabelle Moretti, Zhaksylyk Kabashev, Milovan Fustic

“…Key strategies to mitigate the detrimental effects of climate change include a rapid transition to green, zero-carbon energy sources coupled with geological storage of CO₂. Mineral trapping of CO₂ recently emerged as one of the most efficient and lowest-risk approaches for long-term CO₂ sequestration. …”
Get full text

Longitudinal optimal analytical midcourse guidance for cruise-glide integrated hypersonic vehicles by Xin Li, Guangbin Cai, Hui Xu, Jianwen Zhu, Chaoxu Mu

Get full text

The Role of Anti-Interferon-α Autoantibodies in Severe COVID-19: Implications for Vaccination Prioritization by Xin Rong Lim, Shiyu Liu, Hwee Siew Howe, Khai Pang Leong, Elampirai Elangovan, Chiung-Hui Huang, Kok Ooi Kong, Bernard Yu Hor Thong, Shawn Vasoo, Bernard Pui Lam Leung

Get full text