Variables asociadas a alteraciones cognitivas en una cohorte de personas sobrevivientes por COVID-19 en hospital de tercer nivel de México by M. Rodríguez-Rodríguez, Y. Rodríguez-Agudelo, F.J. Soto-Moreno, A. García-Santos, D. López-González, M. González-Navarro, F. Paz-Rodríguez, M. Chávez-Oliveros, S. Lozano-Tovar, K. González-Alonso, A. Castorena-Maldonado, R. Carrillo-Mezo, O. Marrufo-Meléndez, A. Gutiérrez-Romero, M. del Río Quiñones, A. Arauz-Góngora, S. Avila-Rios

“…Objetivo: Describir alteraciones cognitivas PC-19 e identificar variables asociadas y comparar el impacto de la ventilación mecánica en los resultados cognitivos y de neuroimagen. …”
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Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection. by Ragini Agrawal, Virender Kumar Pal, Suhas K S, Gopika Jayan Menon, Inder Raj Singh, Nitish Malhotra, Naren C S, Kailash Ganesh, Raju S Rajmani, Aswin Sai Narain Seshasayee, Nagasuma Chandra, Manjunath B Joshi, Amit Singh

“…GYY4137 treatment reduced the expression of inflammatory cytokines and re-established the expression of Nrf2-dependent antioxidant genes in the lungs of SARS-CoV-2-infected mice. Notably, non-invasive measurement of respiratory functions using unrestrained whole-body plethysmography (uWBP) of SARS-CoV-2-infected mice showed improved pulmonary function variables, including pulmonary obstruction (Penh), end-expiratory pause (EEP), and relaxation time (RT) upon GYY4137 treatment. …”
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Reinforcement Learning-Based Formulations With Hamiltonian-Inspired Loss Functions for Combinatorial Optimization Over Graphs by Redwan Ahmed Rizvee, Raheeb Hassan, Md. Mosaddek Khan

“…Recently, PI-GNN, a generic framework, has been proposed to address CO problems over graphs based on QUBO with Hamiltonian loss function to train the underlying GNN architecture. …”
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A Nonlinear System State Estimation Method Based on Adaptive Fusion of Multiple Kernel Functions by Daxing Xu, Aiyu Hu, Xuelong Han, Lu Zhang

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Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19 by Benjamin L Spector, Boryana Koseva, Rebecca McLennan, Dithi Banerjee, Kamani Lankachandra, Todd Bradley, Rangaraj Selvarangan, Elin Grundberg

“…We also identified hypermethylation of ELF5 binding sites suggesting downregulation of ELF5 targets in the nasal cavity as a factor in COVID-19 phenotypic variability. Conclusions This study demonstrated DNA methylation as a marker of the immune response to SARS-CoV-2 infection, with enhancer-like elements playing significant roles. …”
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Tool Used to Assess Co-Benefits of Nature-Based Solutions in Urban Ecosystems for Human Wellbeing: Second Validation via Measurement Application by Karmele Herranz-Pascual, Paula Anchustegui, Carolina Cantergiani, Ioseba Iraurgi

“…The most relevant contextual variables to explain the psychosocial co-benefits are openness, the surfaces covered by tree branches, the water surface area, and naturalisation.…”
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Characteristics of hypertension and its impact on cognitive functions in older adults: a cross-sectional study by Nivedita Parandiyal, Porimita Chutia, Shashank Saurabh Sinha, Pratyaksha Pandit, Naif Ali Majrashi, Naseem Qureshi, Shailendra Mohan Tripathi, Shailendra Mohan Tripathi

“…The chi-square test and independent t-tests were used and p value < 0.05 was considered to be significant.ResultThe mean age of the study population was 68.2 years, the cognitive functions was comparable in terms of age, sex, locality, co-morbidity, and treatment characteristic. …”
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Increased functional connectivity of amygdalar-frontal pathways in patients with alcohol use disorder and childhood trauma by Elisabeth Jehli, Fabienne Burri, Niklaus Denier, Franz Moggi, Andrea Federspiel, Roland Wiest, Maria Stein, Tobias Bracht, Matthias Grieder, Leila M. Soravia

“…Childhood trauma (CT) often co-occurs with alcohol use disorder (AUD) and is associated with poor treatment outcome. …”
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Near-source wastewater surveillance of SARS-CoV-2, norovirus, influenza virus and RSV across five different sites in the UK. by Jay C Bullen, Mina Mohaghegh, Fatima Tahir, Charlotte Hammer, Jacob Sims, Frederico Myers, Lucas Eisinger, Ali Reza Kasmati, Claire F Trant

“…The key findings are (1) near-source wastewater detections were linked to local events (staff sickness, enhanced cleaning, changing populations); (2) wastewater detections decreased in the order norovirus GII > norovirus GI > SARS-CoV-2 ≈ influenza A ≈ RSV A > influenza B ≈ RSV B; (3) correlation between near-source wastewater data and national surveillance data increases as a function of catchment size and viral prevalence (examples include the SARS-CoV-2 BA.4/BA.5 variant peak at a museum and wastewater tracking the winter norovirus season); (4) strong weekday periodicity in near-source wastewater SARS-CoV-2 detections, with the correlation against COVID-19 case numbers increasing when modelling variable lag times between faecal shedding onset and clinical diagnosis (R2 = 0.45 increases to 0.84-0.86); (5) a log-linear relationship between the frequency of wastewater SARS-CoV-2 detection and log(catchment size⋅viral prevalence) (R2 = 0.6914-0.9066). …”
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Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. by Heidi Storgaard, Lise L Gluud, Cathy Bennett, Magnus F Grøndahl, Mikkel B Christensen, Filip K Knop, Tina Vilsbøll

“…<h4>Objective</h4>Sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are a novel drug class for the treatment of diabetes. …”
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Unveiling the Impact of COVID-19 on Ovarian Function and Premature Ovarian Insufficiency: A Systematic Review by Charalampos Voros, Despoina Mavrogianni, Aspasia Minaoglou, Anthi-Maria Papahliou, Vasileios Topalis, Antonia Varthaliti, Dimitris Mathiopoulos, Panagiota Kondili, Menelaos Darlas, Agni Pantou, Sophia Sina, Antonia Athanasiou, Diamantis Athanasiou, Dimitrios Loutradis, Georgios Daskalakis

“…SARS-CoV-2 disrupts ovarian function largely through oxidative stress, inflammation, and immunological dysregulation, which are enhanced by its entrance into ovarian tissues via ACE2 receptors. …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…We used it to assess the effect of long-term consumption of total and non-fermented dairy on cognitive function. Methods We included 43,836 individuals over 55 years old with genotyping, dietary data, and cognitive function measurements from three population-based studies: CoLaus|PsyCoLaus (Switzerland), the Rotterdam Study (the Netherlands) and the Canadian Longitudinal Study on Aging (CLSA - Canada). …”
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Kiperin Postbiotic Supplement-Enhanced Bacterial Supernatants Promote Fibroblast Function: Implications for Regenerative Medicine by Lutfiye Karcioglu Batur, Cuneyd Yavas, Yağmur Ekenoğlu Merdan, Ashabil Aygan

“…Gene expression analyses revealed no statistically significant changes, though variable trends were observed across treatment groups. …”
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The exactness of the ℓ1 penalty function for a class of mathematical programs with generalized complementarity constraints by Yukuan Hu, Xin Liu

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Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity by Sukrit Silas, Héloïse Carion, Kira S. Makarova, David Sanchez Godinez, Surabhi Haniyur, Lucy Volino, Wearn-Xin Yee, Andrea Fossati, Danielle Swaney, Michael Bocek, Eugene V. Koonin, Joseph Bondy-Denomy

“…Here, using a functional screening platform to systematically explore the functions of phage accessory genes, we describe how cell-surface barriers can obscure the phenotypes of intracellular defenses in E. coli isolates. …”
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Inhibiting CFTR through inh-172 in primary neutrophils reveals CFTR-specific functional defects by Ana Lúcia Da Silva Cunha, Marfa Blanter, Janne Renders, Mieke Gouwy, Natalie Lorent, Mieke Boon, Sofie Struyf, Marianne S. Carlon

“…The inh-172 model disregards donor variability and allows pinpointing neutrophil functions directly impaired by dysfunctional CFTR.…”
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Integrated approach for estimating climate change impacts on CO2 sink capacity of inland waterbodies using hydrodynamic modelling and GIS analysis by Hanady H. Khalil, Mohamed A. Abdrabo, Mahmoud A. Hassaan, Mohamed M. Elshemy

“…Abstract As one of their key regulatory ecosystem functions, inland lakes serve as CO2 sinks. The CO2 sink capacity of inland lakes depends on their water temperature and salinity as well as their water volume which are all highly sensitive to climate conditions. …”
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Correlation between Rainfall and Runoff in Fuchun River Basin Based on Copula Functions and Kernel Density Estimation by YANG Sheng-mei, ZHU De-kang, CHENG Xiang, LI Bo, ZHU Yan-ze, MA Wen-sheng

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Identification of time-varying parameters of a monthly Budyko function in US MOPEX catchments and its implications by Weibo Liu, Pan Liu, Lei Cheng, Xiaojing Zhang, Liting Zhou

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Reconstruction of ionospheric VTEC using empirical orthogonal function and its performance during extreme geomagnetic storm by Rajat Acharya, Victor Dey

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