Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues. by Giuseppe Orsomando, Lucia Cialabrini, Adolfo Amici, Francesca Mazzola, Silverio Ruggieri, Laura Conforti, Lucie Janeckova, Michael P Coleman, Giulio Magni

“…Final assay validation was achieved in a tissue extract by comparing the activity and expression levels of individual isozymes, considering their distinctive catalytic efficiencies. Furthermore, considering the key role played by NMNAT activity in preserving axon integrity and physiological function, this assay procedure was applied to both liver and brain extracts from wild-type and Wallerian degeneration slow (Wld(S)) mouse. …”
Get full text

Handwritten Words Image Character Extraction Adaptive Algorithm Based on the Multi-branch Structure by GUO Xiaojing, ZHAO Xiaoyuan, ZOU Songlin

“…Higher identification precision and efficiency serve as reference indices for evaluating the model. …”
Get full text

Digital Twin Control Method of Machine Tool Feed Rate Based on Fuzzy Neural Network by YIN Jia, BAI Lele, TIAN Hui, WU Shijie, Hou Guijin, TANG Yuyang, LIU Hongguang, ZHANG Jun

“…The role of the digital twin in the cutting process is to connect machine tools with the developed digital monitoring system so that the machine tools can realize condition monitoring and adaptive optimization in the process of complex parts machining, and improve the machining accuracy and efficiency of parts. In the current milling process of aviation parts, considering many factors such as deformation, roughness, and tool wear, process engineers always set conservative parameters based on experience, resulting in low machining efficiency, and an inability to adaptively adjust the cutting parameters according to the cutting trajectory and machine load. …”
Get full text

Study of the possibility of controlling the production of low-molecular-weight heparin preparations by domestic test systems (review) by A. L. Berkovsky, E. V. Sergeeva, A. V. Suvorov

“…The data on the wide clinical use of low-molecular-weight heparin (LMWH) preparations are presented, necessitating the need for efficient and high-quality production of appropriate pharmaceuticals. …”
Get full text

A Comparative Study of Deep Reinforcement Learning Algorithms for Urban Autonomous Driving: Addressing the Geographic and Regulatory Challenges in CARLA by Yechan Park, Woomin Jun, Sungjin Lee

“…To evaluate the adaptability of each algorithm to geographical variability and complex traffic laws, scenario-specific reward and penalty functions were carefully designed and incorporated. …”
Get full text

Replacing GRACE/GRACE‐FO C30 With Satellite Laser Ranging: Impacts on Antarctic Ice Sheet Mass Change by Bryant D. Loomis, Kenneth E. Rachlin, David N. Wiese, Felix W. Landerer, Scott B. Luthcke

“…The C30 coefficient, which has a large impact on the recovered Antarctic Ice Sheet mass changes, is shown here to be poorly observed by GRACE/GRACE‐FO when either mission is operating without two fully functional accelerometers. …”
Get full text

Expression variation and covariation impair analog and enable binary signaling control by Kyle M Kovary, Brooks Taylor, Michael L Zhao, Mary N Teruel

“…Such high variation is beneficial for population‐level regulation of cell functions but abolishes accurate single‐cell signal transmission. …”
Get full text

The Effect of Rural Guide Plan on Objective Quality of Life among Rural Communities in Fariman County by Aliakbar Anabestani, Hamdollah Sojasi Qeidari, Fahime Jafari

“…According to the results of Pearson's correlation tests, the findings of present study showed a significant and strong correlation between implementation of rural guide plan and the mental facet of life quality by a 0.75 correlation coefficient, so that rural guide plan explained 57% of the variation of dependent variable, and among guide plan dimensions the changing environmental rural affected the objective improvement of life quality of villagers by 29 percent. …”
Get full text

Economic and environmental power dispatch for energy management systems applied to microgrids with wind energy resources and battery energy storage systems by Jhon Montano, John E. Candelo-Becerra, Cristian Escudero-Quintero, Juan Pablo Guzmán

“…The results show that the approach ensures technical efficiency while minimizing economic and environmental requirements. …”
Get full text

Fault Estimation for Semi-Markov Jump Neural Networks Based on the Extended State Method by Lihong Rong, Yuexin Pan, Zhimin Tong

“…To alleviate network congestion and optimize communication resources, the Round-Robin protocol is adopted to schedule data transmission efficiently. By constructing a Lyapunov–Krasovskii functional and applying the discrete Wirtinger inequality, sufficient conditions are derived to ensure the mean square exponential stability and dissipative performance of the system. …”
Get full text

Agricultural Waste–Derived Biochar for Antibiotics Removal in Aqueous Environment: A Comprehensive Outlook by Varalakshmi Varatharajan, Karthik V., Selvakumar Periyasamy

“…The key elements influencing antibiotic adsorption on biochar, including surface chemistry, pyrolysis conditions, and environmental variables, were discussed in detail. This review focuses specifically on the functional modification of the biochar, the mechanism involved in antibiotic adsorption, and the scalability of this process. …”
Get full text

Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species by Lucille C. Jonas, Lucille C. Jonas, Curtis R. Youngs, Stephan Schmitz-Esser, Stephan Schmitz-Esser

“…Recent publications have uncovered a high degree of variability of the livestock vaginal microbiota, making it difficult to focus functional research on individual microorganisms. …”
Get full text

Dynamic Surrogate Optimization of Vertically Stacked Nanosheet FET Based on Gaussian Process Regression by Christofer N. Yalung, Doldet Tantraviwat

“…Source extension (<inline-formula> <tex-math notation="LaTeX">$S_{ext}$ </tex-math></inline-formula>), drain extension (<inline-formula> <tex-math notation="LaTeX">$D_{ex\mathrm {t}}$ </tex-math></inline-formula>), gate length (<inline-formula> <tex-math notation="LaTeX">$L_{g}$ </tex-math></inline-formula>), nanosheet height (NSh), nanosheet width (NSw), and number of fin (nfin) make up the input variables. In addition to applying normalization to make the weight assignment to the goal functions easier, a penalty component was incorporated to manage the <inline-formula> <tex-math notation="LaTeX">$V_{T}$ </tex-math></inline-formula>. …”
Get full text

DC algorithm for estimation of sparse Gaussian graphical models. by Tomokaze Shiratori, Yuichi Takano

“…Specifically, we convert the cardinality constraint into an equivalent constraint based on the largest-K norm, and reformulate the resultant constrained optimization problem into an unconstrained penalty form with a DC (difference of convex functions) representation. To solve this problem efficiently, we design a DC algorithm in which the graphical lasso algorithm is repeatedly executed to solve convex optimization subproblems. …”
Get full text

Eco-engineered remediation: Microbial and rhizosphere-based strategies for heavy metal detoxification by Arun Karnwal, Gaurav Kumar, Alaa El Din Mahmoud, Joydeep Dutta, Rattandeep Singh, Abdel Rahman Mohammad Said Al-Tawaha, Tabarak Malik

“…Moreover, a detailed understanding of plant–microbe interactions and the role of secondary metabolite signalling in the rhizosphere is essential to improve remediation efficiency. Future strategies should prioritize the application of functional genomics, developing bioinoculants tailored to specific environmental conditions, and implementing robust ecological risk assessments for GEMs. …”
Get full text

Effect of short-term dietary intervention on fecal serotonin, gut microbiome-derived tryptophanase, and energy absorption in a randomized crossover trial: an exploratory analysis by Eiichi Yoshimura, Yuka Hamada, Yoichi Hatamoto, Takashi Nakagata, Hinako Nanri, Yui Nakayama, Chiharu Iwasaka, Takanori Hayashi, Ippei Suzuki, Takafumi Ando, Kazuko Ishikawa-Takata, Shigeho Tanaka, Rei Ono, Michihiro Araki, Hitoshi Kawashima, Yi-An Chen, Jonguk Park, Koji Hosomi, Kenji Mizuguchi, Jun Kunisawa, Motohiko Miyachi

Get full text

Mechanical Properties and Statistical Damage Constitutive Model of Rock under a Coupled Chemical-Mechanical Condition by Yun Lin, Feng Gao, Keping Zhou, Rugao Gao, Hongquan Guo

“…To investigate the mechanical damage evolution process of rock under a coupled chemical-mechanical (CM) condition, an improved statistical damage constitutive model was established using the Drucker-Prager (D-P) strength criterion and two-parameter Weibull distribution. The damage variable correction coefficient and chemical damage variable which was determined by porosity were also considered in the model. …”
Get full text

Optimization of Configuration Design for Underwater Dam Defect Detection Vehicles by Hong-Xia Cheng, Mei-Jie Cao, Peng-Fei Xu, Yan Kai, Zi-Peng Wang, Gang Wan, Qiao Hu

“…Additionally, various configurations were generated using a free deformation method. An optimization function was established with resistance and stability as the objectives, and the optimal result was derived based on the function’s calculation outcomes. …”
Get full text

Alleviative Effect of Exogenous Application of Fulvic Acid on Nitrate Stress in Spinach (<i>Spinacia oleracea</i> L.) by Kangning Han, Jing Zhang, Cheng Wang, Youlin Chang, Zeyu Zhang, Jianming Xie

“…FA application promoted the accumulation of biomass in spinach under nitrate stress and increased chlorophyll content, the net photosynthetic rate, the maximum photochemical quantum yield of PSII (Photosystem II) (Fv/Fm), the quantum efficiency of PSII photochemistry [Y(II)], the electron transport rate, and the overall functional activity index of the electron transport chain between the PSII and PSI systems (PItotal); moreover, FA decreased PSII excitation pressure (1 − qP), quantum yields of regulated energy dissipation of PSII [Y(NPQ)], and the relative variable initial slope of fluorescence. …”
Get full text

RL-Cervix.Net: A Hybrid Lightweight Model Integrating Reinforcement Learning for Cervical Cell Classification by Shakhnoza Muksimova, Sabina Umirzakova, Jushkin Baltayev, Young-Im Cho

“…A novel application of RL for dynamic feature refinement and adjustment based on reward functions was employed to optimize the detection capabilities of the model. …”
Get full text