Unraveling novel variants in the NF1 gene and investigating potential therapeutic strategies by Jianmei Huang, Ke Yang, Yaoping Wang, Xinrui Ma, Wenke Yang, Xiaodong Huo, Jie Bai, Hongjie Zhu, Jinming Wang, Yibing Lv, Shixiu Liao

“…A retrospective analysis of 49 clinical trials over the past 20 years revealed that NF1 therapies predominantly target neurofibromin’s GTPase function. Gene therapies aiming to restore neurofibromin by transducing the truncated NF1-GRD gene have been developed but faced pre-clinical challenges, including cloning capacity, transduction efficiency, and immunogenicity caused by gene delivery. …”
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Age-Related Changes in Corneal Deformation Dynamics Utilizing Scheimpflug Imaging. by Marta E Rogowska, D Robert Iskander

“…Raw Scheimpflug images were used to extract changes in anterior and posterior corneal profiles, which were further modelled by an orthogonal series of Chebyshev polynomial functions. Time series of the polynomial coefficients of even order exhibited a dynamic behavior in which three distinct stages were recognized. …”
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The accuracy of a simple, low-cost GPS data logger/receiver to study outdoor human walking in view of health and clinical studies. by Bénédicte Noury-Desvaux, Pierre Abraham, Guillaume Mahé, Thomas Sauvaget, Georges Leftheriotis, Alexis Le Faucheur

“…<h4>Introduction</h4>Accurate and objective measurements of physical activity and lower-extremity function are important in health and disease monitoring, particularly given the current epidemic of chronic diseases and their related functional impairment.…”
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Natural language processing reveals network structure of pain communication in social media using discrete mathematical analysis by Nobuo Okui, Shigeo Horie

“…The network exhibited a sparse overall density (0.0055) but a high clustering coefficient (0.7700), indicating the presence of distinct thematic communities. …”
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A comprehensive review on the integration of artificial intelligence in friction stir welding for monitoring, modelling, and process optimization by Mostafa Akbari, Ezatollah Hassanzadeh, Yaghuob Dadgar Asl, Amirhossein Moghanian

“…The second section examines process control, emphasizing how AI systems enable real-time monitoring and adaptive control of the welding process. This functionality allows for immediate parameter adjustments, thus significantly improving weld consistency and quality by minimizing defects. …”
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The Effect of Ohmic, High-Pressure Carbon Dioxide (HPCD), and Maceration Extraction methods on Bioactive Compounds of Iranian Brown Algae (Nizimuddinia zanardini) by Atefe Taherkhani, Akram Sharifi, Mohammed Koubaa

“…Marine algae are a rich source of bioactive compounds with promising applications as nutrients, functional food ingredients, and therapeutic agents. …”
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Deep Transfer Learning-Based Performance Prediction Considering 3-D Flux in Outer Rotor Interior Permanent Magnet Synchronous Motors by Moo-Hyun Sung, Soo-Hwan Park, Kyoung-Soo Cha, Jae-Han Sim, Myung-Seop Lim

“…Accurate performance prediction in the design phase of permanent magnet synchronous motors (PMSMs) is essential for optimizing efficiency and functionality. While 2-D finite element analysis (FEA) is commonly used due to its low computational cost, it overlooks important 3-D flux components such as axial leakage flux (ALF) and fringing flux (FF) that affect motor performance. …”
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SCIENTIFIC APPROACH TO A COMPLEX ASSESSMENT OF DETERMINANTS OF THE INSURANCE MARKET DEVELOPMENT OF UKRAINE by L. V. Popova, N. O. Kovalchuk, D. D. Polagnyn

“…The developed model contains a clear list and sequence of stages of the insurance market analysis and a specific methodology for assessing the impact of key factors, characteristic for changing conditions of management, on the efficiency of its functioning. Practical application allows to take into consideration the influence of individual determinants of the insurance market development on its condition, to increase the efficiency of managerial decisions in this area. …”
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Classification of traffic accidents’ factors using TrafficRiskClassifier by Wei Sun, Lili Nurliyana Abdullah, Fatimah binti Khalid, Puteri Suhaiza binti Sulaiman

“…Furthermore, the TrafficRiskClassifier model delineates a functional nexus between accident risk and variables such as weather, road conditions, and personal factors, employing a polynomial regression approach. …”
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Explaining the COVID19 mortality growth rate: an empirical analysis of Israeli cities by Yuval Arbel, Yifat Arbel, Amichai Kerner, Miryam Kerner, Miryam Kerner

“…These include population size, median age, a socio-economic ranking at a city level, a date variable and a dummy variable that equals 1 for post-vaccination and 0 for pre-vaccination era.MethodRegression analysis, where each variable is converted to the standard normal distribution function. …”
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Elevator Control Simulation Using Fuzzy Logic Management by Mehr Ali Qasimi, Asmatullah Nashir

“…Within a set of fuzzy rules, three important linguistic variables are added to improve the performance of the elevator group. …”
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COBRAme: A computational framework for genome-scale models of metabolism and gene expression. by Colton J Lloyd, Ali Ebrahim, Laurence Yang, Zachary A King, Edward Catoiu, Edward J O'Brien, Joanne K Liu, Bernhard O Palsson

“…This reformulated model gives functionally identical solutions to previous E. coli ME-models while using 1/6 the number of free variables and solving in less than 10 minutes, a marked improvement over the 6 hour solve time of previous ME-model formulations. …”
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Can digital transformation improve the transparency and accountability of Indonesian public governance? by M. Irwan Tahir, Ani Martini, Anak Agung Ngurah Gunawan, Yogi Makbul, Nirma Yossa, Wisber Wiryanto, Moch Fahrudin, Rahmat Ilya

“…Public administration can increase transparency, efficiency, public participation and data-based decision-making. …”
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A Robust Adaptive Strategy for Diesel Particulate Filter Health Monitoring Using Soot Sensor Data by Bilal Youssef

“…This study investigates an advanced diagnostic strategy to assess particulate filter health based on resistive soot sensors and available engine variables. The sensor data are projected to generate a 2D signature that reflects the changes in filtration efficiency. …”
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Public Procurement Reforms and Service Delivery in Rubanda District Uganda. by Niwagaba, Ivan

“…This underlay on the following objectives that is to assess the effect of compliance with procurement rules and procedures on service delivery, evaluate the relationship between procurement forms and service delivery and assess the effect of staffing and functionality of procurement committees on service delivery in Rubanda District. …”
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Finite Difference/Fractional Pertrov–Galerkin Spectral Method for Linear Time-Space Fractional Reaction–Diffusion Equation by Mahmoud A. Zaky

“…The Pertrov–Galerkin spectral method is adapted using non-smooth generalized basis functions to discretize the spatial variable, and the L1 scheme on a non-uniform graded mesh is used to approximate the Caputo fractional derivative. …”
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Analysis of Hydrological and Meteorological Conditions in the Southern Baltic Sea for the Purpose of Using LNG as Bunkering Fuel by Ewelina Orysiak, Jakub Figas, Maciej Prygiel, Maksymilian Ziółek, Bartosz Ryłko

“…The southern Baltic Sea is characterized by highly variable weather conditions, particularly in autumn and winter, when storms, strong westerly winds, and temporary sea ice formation disrupt maritime operations. …”
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Design of Hall power supply based on full bridge half bridge switching digital LLC resonant converter by Xu Tinghao, Wang Shaoning, Liu Aohui

“…The LLC resonant converter is studied for half bridge full bridge dynamic topology switching and soft start, achieving high efficiency and wide range output. By establishing a fundamental model of LLC resonant converter, analyzing the characteristic curves of frequency and gain, selecting the values of K and Q, variable frequency control output voltage is achieved, and a low peak full bridge half bridge switching mode based on simultaneous frequency conversion and variable duty cycle is designed. …”
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Decentralized queue control with delay shifting in edge-IoT using reinforcement learning by Viacheslav Kovtun

“…Analytical expressions for key QoS indicators (delay, variability, loss, energy consumption) as functions of the shift parameter are derived, and a multi-factor reward function is constructed. …”
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The Cerebellum Posterior Lobe Associates with the Exophthalmos of Primary Hyperthyroidism: A Resting-State fMRI Study by Wen-Feng Liu, Yong-Qiang Shu, Pei-Wen Zhu, Biao Li, Wen-Qing Shi, Qi Lin, Yu-Xin Liu, Meng-Yao Zhang, You-Lan Min, Qing Yuan, Yi Shao

“…The interrelationships between the DC values and clinical variables in the patients with EOPH were evaluated using Pearson’s correlation coefficient. …”
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