Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against <i>Klebsiella pneumoniae</i> Infection by Svetlana V. Dentovskaya, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Alena S. Kartseva, Tatiana A. Ivashchenko, Vladimir N. Gerasimov, Mikhail E. Platonov, Victoria V. Firstova, Andrey P. Anisimov

“…Previously, this kit made it possible to generate bacterial cells of <i>Yersinia pestis</i> with varying degrees of hydrolysis and variable protective activity. <b>Results:</b> In the current study, we showed that co-expression of the holin and endolysin genes from the L-413C phage elicited more rapid and efficient <i>K. pneumoniae</i> lysis than lysis mediated by only single gene <i>E</i> or the low functioning holin–endolysin system of λ phage. …”
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Three Decades of Land Cover Dynamics in a Boreal Coastal Basin: A Multisensor Spectral Index and Machine Learning Approach Using Landsat Data and GB-SAR Data by Jinsong Zhang, Bochi Zou, Yifei Yuan, Asad Khan, Muhammad Bilawal Junaid, Qaiser Abbas, Rana Muhammad Zulqarnain, Nazih Y. Rebouh, Olga D. Kucher, Hassan Alzahrani

“…Boreal coastal habitats, with their complex hydrological, ecological, and geological functions, play a pivotal role in regulating regional climate, supporting biodiversity, and sustaining local communities. …”
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Flow Characteristics of Distinctly Viscous Multilayered Intestinal Fluid Motion by S. K. Pandey, M. K. Chaube, Dharmendra Tripathi

“…The effects of power law index and viscosities on pressure across one wavelength, mechanical efficiency, and trapping are discussed numerically. …”
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Grid-connected PV inverter system control optimization using Grey Wolf optimized PID controller by Monika Gupta, P. M. Tiwari, R. K. Viral, Ashish Shrivastava, Basem Abu Zneid, Iryna Hunko

“…Conventional controllers such as P and PI are widely used in PV applications due to their simplicity, but they exhibit notable limitations in dynamic environments, including increased Total Harmonic Distortion (THD), slower transient response, and poor voltage regulation—particularly under variable irradiance conditions. The proposed GWO-PID method overcomes these limitations by leveraging the GWO algorithm’s global search capability to dynamically optimize the PID gains (Kp, Ki, Kd) based on a composite fitness function that minimizes Mean Squared Error (MSE) and THD. …”
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Modeling Wetland Biomass and Aboveground Carbon: Influence of Plot Size and Data Treatment Using Remote Sensing and Random Forest by Tássia Fraga Belloli, Diniz Carvalho de Arruda, Laurindo Antonio Guasselli, Christhian Santana Cunha, Carina Cristiane Korb

“…Remote sensing (RS) data effectively estimate and map AGB and Corg in wetlands using various techniques, but there is still room to improve the efficiency of machine learning (ML)-based approaches. …”
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Modeling of project activities for UAV modernization to conduct swarm drone attack missions by Oleg Fedorovych, Leonid Malieiev, Oleksii Hubka, Andrei Popov

“…The models are intended to optimize new functions related to control, coordination, and navigation, enabling UAVs to perform as part of drone swarms in military missions. …”
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Early Predictive Value of the Glucose‐to‐Lymphocyte Ratio for the Occurrence of Stroke‐Associated Pneumonia by Fuqiang Zhou, Liju Ma, Min Li, Haijiang Li, Heying Yang, Ye Xu, Kuankuan Dang, Fengchen Gao, Haimei Sun

“…The GLR was converted into a categorical variable for trend testing, and compared the predictive efficiency of GLR through the receiver operating characteristic (ROC) curve and Bonferroni correction analysis. …”
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Sensitivity to Instruction Strategies in Motor Learning Is Predicted by Anterior–Posterior TMS Motor Thresholds by Michael L. Perrier, Kylee R. Graham, Jessica E. Vander Vaart, W. Richard Staines, Sean K. Meehan

“…Recent transcranial magnetic stimulation (TMS) studies suggest that variability in interneuron recruitment by anterior–posterior (AP) currents is linked to differences in functional connectivity between premotor and motor regions. …”
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Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms by Hamed Naderi, Mohammad Ali Rastegar Sorkhe, Bakhtiar Ostadi, Mehrdad Kargari

“…With advancements in technology, more sophisticated techniques—such as reinforcement learning methods (e.g., DQN, Q-Learning, DDPG, and Meta-Learning)—could enhance the accuracy and efficiency of operational risk prediction models.…”
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Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…In particular, the multivariate model, composed of a combination of serine, glycine, arginine, and quinolinic acid, could most efficiently stratify patient OS (concordance index=0.775, HR=3.23, 95% CI 2.04 to 5.26). …”
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Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study by Nurgeldi Manap, Nagmet Mursalov, Mukhtar Abilmazhinov

“…Exclusion criteria: other operative approaches to pelvic bones and patients under 18 years of age. 21 patients underwent surgery with the use of modified Stoppa approach (group A) and 10 surgeries were performed using the ilioinguinal approach (group B). Efficiency was evaluated by comparison of duration of surgical procedures, amount of blood lossbetween groups, size of skin incision, quality of reduction and functional outcomes. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Actigraphy was used to evaluate sleep and circadian rhythm, while HRV was monitored for 24 hours to assess autonomic nerve function. Nonparametric indicators were calculated to quantify the active-rest patterns, including interdaily stability, intradaily variability, the most active 10 consecutive hours (M10), the least active 5 consecutive hours (L5), the relative amplitude, and the actigraphic dichotomy index. …”
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International Natural Uranium Price Prediction Based on TF-CNN-BiLSTM Model by YANG Jingzhe, XUE Xiaogang

“…The Transformer component efficiently models long-range dependencies, the CNN component extracts local features, and the BiLSTM component integrates bidirectional contextual information. …”

The Design and Analysis of a Lightweight Robotic Arm Based on a Load-Adaptive Hoisting Mechanism by Ruchao Wang, Zhiguo Lu, Yiru Wang, Zhongqing Li

“…The proposed design integrates a spring-loaded rope and a variable radius reel into the gripper, enabling efficient load adaptability with minimal structural complexity. …”
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Effects of Indoor Air Quality on Human Physiological Impact: A Review by Tong Nie, Guofu Zhang, Yinan Sun, Wenhao Wang, Tianai Wang, Haoyan Duan

“…Through an analysis of cardiovascular biomarkers (heart rate variability, blood pressure), respiratory parameters, and neurological indicators (electroencephalogram patterns), we identify the mechanisms linking air quality degradation to impaired physiological functioning. …”
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Perinatal bisphenol A exposure impairs gut microbial colonization: Implications for offspring obesity and neurodevelopment by Ana López-Moreno, Alfonso Torres-Sánchez, Antonio Suárez, Alicia Ruiz-Rodríguez, Margarita Aguilera

“…Toxicological approaches in animal models have revealed complex effects, using variable doses of BPA, on reproduction, development, obesity, immune function, metabolic and systemic toxicity. …”
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Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Additionally, luciferase assay was employed to evaluate the cytotoxic efficiency of Trop2-targeted therapy at various effector-to-target ratios. …”
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Enhancing access to specialist appointments in tertiary healthcare in Shanghai, China: a structured reservation pathway using digital health technologies by Li Li, Tao Zheng, Enhong Dong, Minjie Chen, Xiaojing Zhao, Binyuan Zhang, Xuji Zhao, Weijun Shao, Yiling Fan

“…Objective The aim of this study is to develop, implement the precise reservation path (PRP) and investigate its prediction function for scheduling shunting patients for specialist appointment registration in Shanghai, China.Design The PRP system was built on the hospital’s existing information system, integrated with WeChat (WeCom) for user convenience. …”
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Causal relationships of vegetation productivity with root zone water availability and atmospheric dryness at the catchment scale by G. W. Abeshu, H.-Y. Li, M. Shi, L. R. Leung

“…Seasonal climatic, hydrological, and vegetation characteristics were represented using the Horton index, ecological aridity index, evaporative fraction index, and carbon uptake efficiency. Statistical methods, including circularity statistics, correlation analysis, and causality tests, were employed to determine the complex interactions between catchment wetness, atmospheric dryness, and vegetation carbon uptake. …”
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A Particle Swarm Optimization-Guided Ivy Algorithm for Global Optimization Problems by Kaifan Zhang, Fujiang Yuan, Yang Jiang, Zebing Mao, Zihao Zuo, Yanhong Peng

“…In recent years, metaheuristic algorithms have garnered significant attention for their efficiency in solving complex optimization problems. …”
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