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    Real-World Assessment of the Association Between PCSK9i Adherence and LDL Reduction and Variability in a Chinese Clinical Practice by Ye X, Zhang S, Zhong X, Li M, Liu M, Zhuang X, Liao X

    Published 2025-06-01
    “…Xiaomin Ye,1,2,* Shaozhao Zhang,1,2,* Xiangbin Zhong,1,2 Miaohong Li,1,2 Menghui Liu,1,2 Xiaodong Zhuang,1,2 Xinxue Liao1,2 1Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2NHC Key Laboratory of Assisted Circulation, Sun Yat-Sen University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xinxue Liao, Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, 510080, People’s Republic of China, Tel +86-13903063724, Fax +86-020-28823388, Email liaoxinx@mail.sysu.edu.cn Xiaodong Zhuang, Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, 510080, People’s Republic of China, Tel +86-13760755035, Email zhuangxd3@mail.sysu.edu.cnBackground: Real-world evidence about adherence to proprotein convertase subtilisin/kexin type-9 inhibition (PCSK9i) is needed in Chinese population.Objective: We aimed to evaluate the adherence patterns using anti-PCSK9 monoclonal antibody in Chinese clinical practice and explored the association between adherence to PCSK9i and low-density lipoprotein cholesterol (LDL-C) reduction ratio and variability.Methods: A total of 5373 patients initiating PCSK9i in the First Affiliated Hospital of Sun Yat-sen University were included as sub-analysis of the RED-CARPET registry. …”
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  10. 370

    Stormwater Management and Late-Winter Chloride Runoff into an Urban Lake in Minnesota, USA by Neal D. Mundahl, John Howard

    Published 2025-03-01
    “…Stormwater runoff containing road deicing salts has led to the increasing salinization of surface waters in northern climates, and urban municipalities are increasingly being mandated to manage stormwater runoff to improve water quality. …”
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    Impact of pavement friction decay on speed limits and autonomous vehicles: A theoretical and experimental study by Filippo Giammaria Praticò

    Published 2025-03-01
    “…Unfortunately, not only do these reference values not correspond to a given standard to measure them, but nothing is said about the decrease of the posted speed limit (variable speed limits) when roads become slippery and lanes for autonomous vehicle (AV) are concerned.Furthermore, the same assessment of the friction coefficient has plenty of uncertainties due to measurement device, temperature, location, time passed from the construction, alignment-related variables (e.g., curve, tangent, transition curve, convexity/crests or concavity/sags, longitudinal slope, superelevation, and ruling gradient), and supplementary singularities such as joints and bridge approaches. …”
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    A Model for the Crash Occurrence in Unexpected Incidents by Pouliou Anna, Kehagia Fotini, Meselidis Christos

    Published 2025-02-01
    “…It investigates the effect of different road and environment parameters (road category and complexity of the environment, visibility conditions), parameters of the driver (age, gender, mental workload), physiological parameters of the driver (heart rate, skin conductance, skin temperature) and the reaction time of the driver to the unexpected incidents, as well as the way of reaction (brake, maneuver, both, none). …”
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    Jaguar at the Edge: movement patterns in human-altered landscapes by Vanesa Bejarano Alegre, Claudia Zukeran Kanda, Júlia Emi de Faria Oshima, Bernardo Brandão Niebuhr, Ronaldo Gonçalves Morato, Jeffrey J Thompson, Luca Börger, Milton Cezar Ribeiro

    Published 2024-10-01
    “…Human-caused habitat loss and fragmentation have significantly impacted the natural environments of large carnivores, altering their movement patterns and increasing risks such as hunting and road collisions. This study aims to understand the movement of jaguars (Panthera onca) through forests, agriculture of varying patch sizes, their distances to these structures, and roads and drainages. …”
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    Passenger car emissions in urban areas based on local vehicle fleet and environmental conditions by A. Valdés-Montenegro, F.G. Gonzalez-Olivardia, C. Pinzón-Acosta

    Published 2025-07-01
    “…Additionally, the study considered geographic and environmental variables, including travel patterns on urban roads, fuel specifications, and elevation.FINDINGS: 53 vehicle categories were identified across the province and classified within the international vehicle emission model. …”
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    Conical Mecanum Wheel of Adjusting Roller Offset Angle based on Spherical Four-bar Mechanism by Qingshan Wang, Lubin Hang, Weizhong Guo, Xiaobo Huang, Chenkun Qi, Yan Wang

    Published 2019-07-01
    “…As a kind of omnidirectional walking wheel, Mecanum wheel is widely used in many fields, to solve the limitation of Mecanum motion system on smooth road surface,a new variable cone angle Mecanum wheel which can be extended to the V type road surface is proposed. …”
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