-
4921
Gut mycobiome maturation and its determinants during early childhood: a comparison of ITS2 amplicon and shotgun metagenomic sequencing approaches
Published 2025-05-01“…Candida albicans exhibited altered abundance dynamics in association with perinatal antibiotic exposure and birth mode for both sequencing approaches. Post hoc analyses suggested that the birth mode association could be driven by exposure to perinatal antibiotics in children delivered by cesarean section rather than by birth mode itself.DiscussionIn summary, amplicon and metagenomic sequencing approaches provide generally similar results with respect to mycobiome maturational dynamics and the contribution of clinical variables to variation. …”
Get full text
Article -
4922
Factors associated with PEP awareness among adolescent girls and young women in Eswatini
Published 2025-06-01“…Despite the World Health Organization's 2014 recommendation for post‐exposure prophylaxis (PEP) to be available for all HIV exposures, it has been underutilized among youth. …”
Get full text
Article -
4923
Comparative Cost Analysis for Direct Medical Costs of Protocol Administration of Non-Small Cell Lung Cancer Treatment Regimens in Curative Intent: A Micro-Costing Study in Jordan
Published 2025-07-01“…Maximum cycle costs were: targeted therapy (Osimertinib) $7,206.44, immunotherapy (Durvalumab) $9,057.71, immune-chemotherapy (Durvalumab-Carboplatin-Pemetrexed) $11,358.43, and chemotherapy (Carboplatin-Pemetrexed) $2,300.72.Conclusion: Our results highlight the substantial economic impact and cost variability among treatment regimens. This variability presents opportunities for cost reduction through careful selection of therapeutically equivalent regimens based on pricing and toxicity profiles. …”
Get full text
Article -
4924
Investigating Protective and Risk Factors and Predictive Insights for Aboriginal Perinatal Mental Health: Explainable Artificial Intelligence Approach
Published 2025-04-01“…To make the black-box model interpretable, post hoc explanation techniques including Shapley additive explanations and local interpretable model-agnostic explanations were applied. …”
Get full text
Article -
4925
Análisis comparativo de los perfiles motivacionales y el Estado de Flow entre una metodología tradicional y la metodología Flipped Classroom en estudiantes de Educación Física (Co...
Published 2021-01-01“…To observe intra-group differences (pre vs. post-test), a T-Student test was detected for related samples. …”
Get full text
Article -
4926
Demographic and clinical impact on preoperative BREAST-Q ePROM completion and baseline outcomes in women undergoing breast cancer surgery: a quantitative descriptive study at a Dan...
Published 2025-01-01“…The BREAST-Q is a PROM in questionnaire format, developed and validated to assess satisfaction and quality of life for breast surgery patients.The hypothesis tested is that considering disparities in geography, age and education among responders is essential for capturing a diverse patient population in future Patent-Reported Outcome Measures initiatives, examining how these characteristics are associated with Patent-Reported Outcome Measures utilisation and outcomes.Design Quantitative descriptive study.Setting Electronic Patient-Reported Outcome Measures were collected between 6 September 2021 and 5 September 2022 from patients recruited from an outpatient clinic at a Plastic- and Breast Surgery Department at a University Hospital in Denmark.Participants Participants include a total of 629 Danish-speaking women diagnosed with breast cancer and scheduled for breast cancer surgery, with a final participation rate of 468.Intervention Preoperative ePROMs and demographic data were collected between September 2020 and 2021 through patients’ secure national digital post-box.Main outcome measures Demographic variables of both responders and non-responders were assessed using t-tests, Mann-Whitney U tests and χ2 tests. …”
Get full text
Article -
4927
A Guideline for the Evolution of Quantitative Accounting Research in Iran: Shifting from Local to International Scientific Patterns
Published 2025-03-01“…Attention is also given to measurement errors in the interest variables of the study. Control variables are categorized into “good” (correlated) and “bad” (colliders, homogeneous construct, high measurement error). …”
Get full text
Article -
4928
The impact of a lifestyle promotion program on anthropometric and clinical manifestations in adolescents with polycystic ovarian syndrome: a randomized controlled trial
Published 2024-12-01“…Data was analyzed using the non-parametric Mann-Whitney test for variables with two-time point assessments and generalized estimation equations (GEE) for variables with three time point assessments. …”
Get full text
Article -
4929
Efecto de la pandemia de COVID-19 en la natalidad y salud neonatal del Hospital Español de México
Published 2025-06-01“…Se aplicaron pruebas estadísticas como Kolmogorov-Smirnov y Kruskal-Wallis para analizar variables cuantitativas, junto con la prueba post hoc de Bonferroni para identificar diferencias entre grupos. …”
Get full text
Article -
4930
Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses.
Published 2020-12-01“…The main outcome measure for the clinical study was insulin cessation at 1-year post-surgery: relative risks (RR) summarising predictive factors were determined, unadjusted, and after adjusting for variables including age, initial body mass index (BMI), duration of T2DM, and weight loss. …”
Get full text
Article -
4931
Investigating the relationship between clinical competence and the incidence of needle-stick injuries (NSIs) and their contributing factors in nurses: a descriptive cross-sectional...
Published 2025-03-01“…The demographic questionnaire captured variables such as age, gender, marital status, educational background, departmental assignment, work experience, and weekly working hours. …”
Get full text
Article -
4932
Disagreement Persists on Optimal Rehabilitation Goals and Timelines for Weight-Bearing Restriction, Knee Brace Use, and Return to Sports After Posterolateral Corner Reconstruction
Published 2025-06-01“…Overall, 31% of rehabilitative goals and timelines had good-to-excellent agreement rates. Post-2019 consensus, adherence to a stepwise rehabilitative approach significantly improved, especially for initiating strength exercises after muscular endurance exercises (P = .009) and initiating power exercises after strength exercises (P = . 031). …”
Get full text
Article -
4933
One health surveillance: linking human and animal rabies surveillance data in Kenya
Published 2025-06-01“…We estimated incidences and tested the relationships between rabies variables in human and dogs as a proxy for robust data availability.ResultsOn average, there were 162 cases and 84 deaths in dogs, while in humans, there were 53 cases and 6 deaths. …”
Get full text
Article -
4934
Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol
Published 2020-09-01“…The aim of the study is to define microbiota signatures longitudinally throughout pregnancy and the first year post birth, and to identify key clinical and environmental variables that shape the female microbiota profile during and following pregnancy.Methods and analysis The Microbiome Understanding in Maternity Study (MUMS) is an Australian prospective longitudinal cohort study involving 100 mother–infant pairs. …”
Get full text
Article -
4935
Development and validation of a model to predict mortality risk among extremely preterm infants during the early postnatal period: a multicentre prospective cohort study
Published 2023-12-01“…Risk factors including maternal and neonatal variables were collected within 1 hour post-childbirth. …”
Get full text
Article -
4936
Optimising neonatal services for very preterm births between 27+0 and 31+6 weeks gestation in England: the OPTI-PREM mixed-methods study
Published 2025-04-01“…We used an instrumental variable approach to control for unmeasured differences between units. …”
Get full text
Article -
4937
Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients
Published 2024-11-01“…Trial registration: Clinical Trial Number (ClinicalTrials.gov): NCT03222258; Study Registration Dates (First submitted: 2017-06-05; First submitted following the QC criteria: 2017-07-16; First posted: 2017-07-19).…”
Get full text
Article -
4938
Depth distributions of soil temperature: Seasonal sensitivity and simulation across dryness/wetness conditions
Published 2025-07-01“…The results indicate the following: (1) A distinct shift in soil thermal dynamics was observed, with a cooling trend prior to 1992 transitioning into a pronounced warming phase thereafter. The post-1992 warming rate was 3–4 times faster than the overall rate for 1966–2022, revealing critical temporal shifts in soil temperature responses. (2) Shallower soil layers (0–40 cm) exhibited heightened seasonal sensitivity to dryness/wetness, responding more rapidly and intensely than deeper layers (>80 cm), especially at short timescales (≤3 months). …”
Get full text
Article -
4939
Ecological drivers of malaria vector habitat and transmission over 1 year of long-lasting insecticidal net intervention in Côte d’Ivoire
Published 2025-08-01“…., and for P. falciparum-infected vectors, at baseline and 1-year post-LLIN intervention. We compared the projected habitat and habitat determinants for each species, and assessed the respective contributions of each intervention arm and environmental factors on the probability of species occurrence. …”
Get full text
Article -
4940
A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy
Published 2025-02-01“…Moreover, students’ academic discipline and other demographic variables were not associated with application status at either the lower division (LD) or upper division (UD) levels. …”
Get full text
Article