Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data by Deniz Türkmen, Xiaoran Liang, Jane A. H. Masoli, Dipender Gill, Luke C. Pilling, Jack Bowden

“…We estimated associations between PDC within 1 year of statin initiation, genetic factors, post-treatment LDL-c reduction, and clinical adverse outcomes. …”
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Artificial intelligence in community pharmacy practice: Pharmacists' perceptions, willingness to utilize, and barriers to implementation by Ashenafi Kibret Sendekie, Liknaw Workie Limenh, Biruk Beletew Abate, Gashaw Sisay Chanie, Abebe Tarekegn Kassaw, Fasil Bayafers Tamene, Kalab Yigermal Gete, Ephrem Mebratu Dagnew

“…Independent samples t-test, one-way ANOVA, and post-hoc analyses were used to compare pharmacists' perception and willingness scores. …”
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The role of vitamin D deficiency and modifiable risk factors in patients with Crohn’s disease by Xiaoyue Feng, Qin Yin, Ying Kang, Kang Jiang, Mengqing Xu, Fangyu Wang

“…After controlling for several variables, multivariate analysis revealed that a lower odds ratio was linked to increasing age at diagnosis (OR: 0.12, 95% CI 0.03-0.85, p=0.02), sex (OR: 0.58, 95% CI 0.44-0.95, p=0.01), iron (OR: 0.44, 95% CI 0.11-0.62, p=0.01), and 25-OH vitamin D total (OR: 0.48, 95% CI 0.25-0.95, p=0.03). …”
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Impact of Body Image Perception on Behavioral Outcomes in Chinese Adolescent and Young Adult Survivors of Sarcoma by Yihui Wei, Chung Tin Ma, Michael Can Heng Li, Keary Rui Zhou, Herbert Ho Fung Loong, Kwok Chuen Wong, Chi Kong Li, Yin Ting Cheung

“…Mediation analyses were performed to examine the mediating effects of body image perception between clinical, treatment, or socioenvironmental risk factors and behavioral outcomes. Results At 15 years post‐cancer diagnosis, one‐third of the cohort (39.7%) reported dissatisfaction with their body image. …”
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Epigenetic age and long-term cancer risk following a stroke by Antoni Suárez-Pérez, Adrià Macias-Gómez, Isabel Fernández-Pérez, Marta Vallverdú-Prats, Elisa Cuadrado-Godia, Eva Giralt-Steinhauer, Maia Campanale, Daniel Guisado-Alonso, Ana Rodríguez-Campello, Joan Jiménez-Balado, Jordi Jiménez-Conde, Angel Ois

“…Our study aims to examine B-age as a novel contributing factor to cancer development post-CVE. Methods From our prospective stroke registry (BasicMar), we selected 940 cases with epigenetic data. …”
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Early diagnosis and survival outcomes in silicosis: a retrospective cohort study of 11,809 patients in Guangdong Province, China (1956–2020) by Chunyue Fan, Yuhao Wang, Yuhao Wang, Jingjing Chen, Qiaoli Wei, Shijie Hu, Lihua Xia, Jiawen Huang, Weihui Liang, Lin Wu, Xudong Li

“…Exclusion criteria included ambiguous diagnosis dates, pre-adolescent exposure, and missing variables. Cox proportional hazards models adjusted for covariates (sex, age, region, industry, exposure duration) were used to assess mortality risks across stages I–III. …”
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Six-month outcomes and effect of pulmonary rehabilitation among patients hospitalized with COVID-19: a retrospective cohort study by Yaoshan Dun, Chao Liu, Jeffrey W. Ripley-Gonzalez, Ping Liu, Nanjiang Zhou, Xun Gong, Baiyang You, Yang Du, Jiyang Liu, Bo Li, Suixin Liu

“…Background Patients appear to maintain sequelae post-coronavirus disease 2019 (COVID-19) affecting daily life and physical health. …”
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SMALL INTESTINAL BACTERIAL OVERGROWTH IN PEOPLE WITH CYSTIC FIBROSIS: SYSTEMATIC REVIEW by Maria Lidiane Lavor LANDIM, José Dirceu RIBEIRO, Daniela de Souza Paiva BORGLI, Danielle Rossana Queiroz Martins BONILHA, Elizete Aparecida LOMAZI, Maria de Fátima Correa Pimenta SERVIDONI

“…ABSTRACT Background: In patients with cystic fibrosis (pwCF) acid suppression therapy, gastrointestinal dysmotility, and post-operative bowel status, may predispose to the development of small intestinal bacterial overgrowth (SIBO). …”
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Identifying lifelong factors that impact brain health and functional outcomes in adults with childhood-onset type 1 diabetes: the cognition and longitudinal assessments of risk fac... by Velandai K Srikanth, Eva L Feldman, Chris Moran, Lili Zhao, Amy Brown, Richard Beare, Elisabeth A Northam, Emily J Koubek, Stacey A Sakowski, Taya Collyer, Chris L. Adamson, Fergus J. Cameron

“…We now introduce the Cognition and Longitudinal Assessments of Risk Factors over 30 Years (CLARiFY) Diabetes Complications Study to assess brain, cognition and functional outcomes in mid-adulthood, approximately 30 years post-T1D onset. Both T1D participants from the original cohort and healthy controls will participate in semistructured interviews, neuroimaging and cognitive testing. …”
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Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort by Claudia Barth, Liisa AM Galea, Emily G Jacobs, Bonnie H Lee, Lars T Westlye, Ann-Marie G de Lange

“…Longer duration of use and older age at last use post-menopause was associated with older gray and white matter brain age, larger white matter hyperintensity volume, and smaller hippocampal volumes. …”
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Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study by Loo WTW, Chew SY, Tan JHY, Soh RY, Koh MS, Lapperre TS, Tiew PY

“…Predictors of 2-year clinical stability included higher body mass index (BMI) (p< 0.001), higher post-bronchodilator FEV1/FVC ratio (p=0.0132), fewer baseline exacerbations (p=0.007), absence of bronchiectasis (p=0.045), preserved hemoglobin levels (p=0.019), and successful smoking cessation (p=0.039). …”
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Civilian death and injury from airstrikes: evidence from the war in Tigray, Ethiopia by Mulugeta Gebregziabher, Akeza Awealom Asgedom, Hiluf Ebuy Abraha, Hale Teka, Abenezer Etsedingl, Tsegay Berihu, Gebru Hailu Redae, Nahom M. Gebreselassie, Araya Abrha Medhanyie, Hagos Godefay, Demoz Gebre-Egziabher, Hannah Wild

“…Descriptive analysis was conducted for variables of interest (e.g., age, sex, location, injury outcomes). …”
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STORCH Brazil: multicenter cohort study protocol to investigate neurodevelopmental paths and functioning in infants exposed to STORCH in Brazil by Daniele Almeida Soares-Marangoni, Amanda de Oliveira Arguelho, Ayrles Silva Gonçalves Barbosa Mendonça, Carine Carolina Wiesiolek, Carolina Daniel de Lima-Alvarez, Eloá Maria dos Chiquetti, Everton Falcão de Oliveira, Márcio José de Medeiros, Silvana Alves Pereira, Renata Hydee Hasue

“…A proposed total sample size of 296 infants will be included at 3 months (12–15 weeks post term). They will be equitably divided into: (a) an exposed group (n = 148), consisting of those diagnosed with any congenital STORCH infection or whose mothers experienced prenatal STORCH infection; (b) an unexposed group (n = 148). …”
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Individual responses to purple grape juice consumption on endurance, explosive power, and fatigue in young male elite soccer players by Alireza Niknam, Kamran Tahmasebi, Mohammad Hemmatinafar, Walaa Jumah Alkasasbeh, Walaa Jumah Alkasasbeh, Mark E. T. Willems, Maryam Koushkie Jahromi, Morteza Bagheri Kalayeh, Mohammad Hadi Zare

“…No effects were found for SLJ or perceived fatigue (P > 0.05), SWC analysis revealed that 77% of participants showed improvements in VIFT and VO2max, and 54% showed improvements in SLJ 5 min post-IFT.ConclusionPurple grape juice supplementation enhanced endurance performance parameters in most participants, with significant individual variability in response. …”
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The Role of Emotions in the Persistence of Tensions and Conflicts in the Middle East (2011–2024) by Sayed Jalal Dehghani Firouzabadi, Fatemeh Damirchi

“…The findings suggest that emotions have exacerbated conflicts in the post-Arab Spring Middle East. Under these conditions, collective emotions and identities have not only played a central role in shaping domestic and foreign policies but have also emerged as significant obstacles to regional cooperation. …”
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Intervención psicomotriz en el trauma infantil: efectos en la reactividad del cortisol (Psychomotor intervention for childhood trauma: the effects on cortisol reactivity) by Talía Morillo Lesme, Pedro Abreu González, Josefa Sánchez Rodríguez, Miguel Llorca Llinares

“…In addition, a great variability is reported between the cortisol levels of each of the subjects, with the total values being higher in the male gender. …”
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Effect of Integrative Balance and Plyometric Training on Balance, Ankle Mobility, and Jump Performance in Youth Football Players: A Randomized Controlled Trial by Andrew Rinaldi Sinulingga, Kristaps Slaidiņš, Anastasija Salajeva, Agris Liepa, Inese Pontaga

“…No significant pre-to-post changes were observed in the CG, except for absolute and relative peak torque of DF by 10–19% (p = 0.01–0.02, d = 0.55–0.91), peak force DF in the dominant leg by 11% (p = 0.04, d = 0.71), and jump height by 5% (p = 0.008,d = 0.82). …”
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Clinical factors predicting the rate of cognitive decline in a US memory clinic: An electronic health record study by Roy Adams, Jeannie‐Marie Leoutsakos, Milap A. Nowrangi, Esther S. Oh, Paul B. Rosenberg, Konstantina Skolariki, Sevil Yasar, Peter P. Zandi, Constantine G. Lyketsos

“…Quicker post‐baseline decline was associated with older age, dementia diagnoses, and cholinesterase inhibitor prescription, while slower decline was associated with a higher number of total prescriptions, distance from home to clinic, and Social Deprivation Index. …”
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Acute severe hypertension in the emergency and acute medicine departments: developing a same-day emergency care (SDEC) hypertension pathway by James Steckelmacher, Barbara Onen, Abubaker Eltayeb, Dawud Masieh, Carmen Maniero, Gillian Fox, Dakshitha Hettiaratchi, Ajay Gupta

“…A comparative sample of ED patients pre-pathway, who would have met criteria for referral to the SDEC hypertension pathway, showed there was an approximately two times greater reduction in BP compared with standard care (discharge from ED directly back to GP) on remote follow-up of BP in the community (Figs 1 and 2); within a 6-month period from initial ED attendance, there were almost three times fewer ED re-attendances in the post- compared with the pre-SDEC cohort, with fewer converting to an acute admission (Fig 2). …”
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Correlation between Pre-procedural Ultrasound-estimated and Actual Procedural Epidural Depth in Lumbar Epidural Anaesthesia Taking BMI into Consideration: An Observational Study by Minu Thomas, Derlin Thomas, John Varghese Thoppil, Paul Ovungal Raphael, Deo Mathew

“…In recent years, there has been growing interest in using ultrasound for lumbosacral regional anaesthesia, even as a preoperative assessment tool. However, the variability in the distance between the skin and the epidural space can make it difficult to accurately locate the space, thereby increasing the risk of complications such as nerve injuries, paresthesia, haematoma formation, and post-dural puncture headache. …”
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