The impact of cell density variations on nanoparticle uptake across bioprinted A549 gradients by Luigi Di Stolfo, Wang Sik Lee, Dimitri Vanhecke, Sandor Balog, Patricia Taladriz-Blanco, Alke Petri-Fink, Alke Petri-Fink, Barbara Rothen-Rutishauser

“…SiO2 NP uptake per cell was around 50% higher in low-density regions compared to high-density areas across all time points, i.e., 6, 24, and 48 h post-exposure. This inverse relationship correlated with greater average cell surface area in lower-density regions, while differences in the proliferation rates of the A549 cells at varying densities did not significantly impact uptake, did not significantly impact uptake.ConclusionSiO2 NP uptake is significantly enhanced at lower cell densities, mainly due to the increased available surface area, revealing potential cell-NP interaction differences in tissues that present cell density variability. …”
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Comparative assessment of biocompatibility of various fluoride agents in cell culture by Bengi Aydınel, Çağla Kayabaşı, Dilşah Çoğulu, Cumhur Gündüz

“…All experiments were performed in triplicate and independently repeated to ensure reproducibility, with data analyzed using non-linear regression for IC₅₀ determination, one-way ANOVA with Tukey’s post hoc test for group comparisons, and chi-square or Fisher’s Exact tests for categorical variables (SPSS 25.0); statistical significance was set at p < 0.05. …”
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Novel non-curable resection prediction model for early colorectal cancer following endoscopic submucosal dissection based on inflammatory immune index by Xiunan Li, Lei Zhang, Biao Xu, Shu Ding, Jing Wang, Jing Wang, Yu Jia

“…Furthermore, patients were stratified according to the presence or absence of non-curative resection outcomes post-ESD, to identify independent risk factors associated with non-curative resection. …”
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A novel glycogene-related signature for prognostic prediction and immune microenvironment assessment in kidney renal clear cell carcinoma by Xuyan Zhao, Hanxiao Cui, Mingjing Zhou, Xueting Ren, Zihao Li, Peinan Liu, Danni Zhao, Shuai Lin, Huafeng Kang

“…Glycosylation is a key post-translational modification that is essential in cancer progression. …”
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Effectiveness of the Integrated Dengue Education and Learning (iDEAL) module in improving the knowledge, attitude, practice, environmental cleanliness index, and dengue index among... by Rahmat Dapari, Kalaivani Muniandy, Ahmad Zaid Fattah Azman, Suhaili Abu Bakar, Mohd Nasir Mohd Desa, Lim Chee Hwa, Sukhvinder Singh Sandhu, Nooreen Farzana Mustapha, Norazman Mohd Rosli, Mohd 'Ammar Ihsan Ahmad Zamzuri, Mohd Rohaizat Hassan, Nazri Che Dom, Syed Sharizman Syed Abdul Rahim, Balvinder Singh Gill, Nurulhusna Ab Hamid

“…The outcome will be measured using validated, self-administered questionnaires at baseline (T0), immediately (T1), one month (T2), and three months (T3) post-intervention to measure the intervention module effectiveness. …”
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One Health intervention for elimination of animal to human disease transmission of Anthrax in an endemic district of Odisha: A baseline and endline study by Dr. Debaprasad Parai, Mr. Matrujyoti Pattnaik, Dr. Hari Ram Choudhary, Dr Arun Kumar Padhi, Dr. Niranjana Sahoo, Dr. Sanghamitra Pati, Dr Debdutta Bhattacharya

“…In Odisha, Koraput district stands out with more than 300 reported human cases and over 10 confirmed deaths due to Anthrax infection in the past six years.The present study is a baseline and endline survey to assess the knowledge, attitude and practices with regards to the anthrax disease among the communities of indigenous population residing in the region pre and post of the tailored made One Health intervention for elimination of human Anthrax in this endemic district. …”
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Environmental, socioeconomic, and sociocultural drivers of monkeypox transmission in the Democratic Republic of the Congo: a One Health perspective by Guangyu Lu, Zeyin Chong, Enyu Xu, Ce Na, Kaixuan Liu, Liying Chai, Pengpeng Xia, Kai Yang, Guoqiang Zhu, Jinkou Zhao, Olaf Müller

“…Moreover, a grey prediction model GM (1, n) was constructed to predict the epidemic trend of mpox post-2015 and validated using suspected mpox case data in the DRC from 2016 to 2021, sourced from the United States Centers for Disease Control and Prevention. …”
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Resistance training as a modulator of inflammation and cognition by Jacqueline Goodrich, Jamie L. Tartar, Jonathan Banks, Francesca Leon, Jose Antonio

“…Participants n = 15 female (18.2 ± .36) untrained undergraduate students completed a baseline assessment, engaged in twice-weekly full-body resistance training, and underwent a post-training assessment. Baseline measures included cognitive performance tasks (Flanker Squared, Simon Squared, and Stroop Squared), saliva collection for IL-6, CRP, and cortisol analysis, body composition testing via InBody, a sleep quality index, and lifestyle assessment. …”
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Effects of simultaneous intervention of aerobic training and berberine supplementation on AMPK and GLUT4 gene expression in the quadriceps muscle of diabetic male rats by Mahboobe Zaefarani Arani, Javad Ramezani, Saeid Naghibi

“…One-way analysis of variance and Tukey's post hoc test were employed for between-group comparisons of the data.   …”
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Quantification of liver fat fraction using T1-weighted mDixon MRI in young patients with ataxia telangiectasia undergoing whole-body MRI: an exploratory study by Soma Kumasaka, Rafal Panek, Renata Neves, Mohnish Suri, Sumit Jagani, Yuka Kumasaka, Yoshito Tsushima, Robert A. Dineen

“…Statistical tests Group comparisons of variables between participants with and without previous diagnosis of liver steatosis were made using independent sample Mann–Whitney U. …”
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Effects of rapid maxillary expansion and functional orthodontic treatment in children with sleep disordered breathing: a systematic review by Magdalena Piełunowicz, Jacek Kotuła, Krzysztof Kotuła, Mieszko Więckiewicz, Joanna Lis, Beata Kawala, Anna Ewa Kuc, Michał Sarul

“…Search filters included the time of the publication—articles of 11 last years and publications that was published in English. The following variables were established for the selected articles: sample size, demographic characteristics, orthodontic treatment methods, type of study, AHI (Apnea–Hypopnea Index) parameter. …”
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Variation in Arterial CO2 is a Stronger Determinant of Brain Tissue Oxygenation Than its Synchronous Value in Critically Ill Patients With Acute Brain Injury by Joanie Martineau, MD, MSc, Francis Bernard, MD, Alexandrine Gagnon, MD, Virginie Williams, PhD, Sabrina Araujo de Franca, BSN, David Williamson, BPharm, PhD, Yiorgos Alexandros Cavayas, MD, Msc

“…DESIGN:. We performed a post hoc analysis of a prospective cohort study collecting arterial blood gas (ABG) values alongside synchronous neuromonitoring variables. …”
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Long-term hepatitis B vaccine immunity in Ethiopian children that received a pentavalent vaccine series: a retrospective cohort study by Dr Tinsae Alemayehu, Dr Million Dechassa Daba, Dr Danilo Buonsenso

“…The magnitude of association between different variables and vaccine-induced hepatitis B immunity was assessed using logistic regression. …”
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Sexual and reproductive health (SRH) knowledge of women: a cross-sectional study among the women experienced abortion in urban slums, Dhaka, Bangladesh by Md Arif Billah, Kamrun Nahar Koly, Farzana Begum, Shakera Naima, Quazi Suraiya Sultana, Tithi Rani Sarker, Elvina Mustary, Md. Mahbubul Haque, Daniel Reidpath, Syed Manzoor Ahmed Hanifi

“…Women with higher education, longer marriages, and who availed post abortion care had high level of SRH knowledge than respective counterparts. …”
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The Diagnostic Value of Bile Acids and Amino Acids in Differentiating Acute Coronary Syndromes by Yu Q, Zhao F, Wang S, Jia X, Shen S, Zhao X, Li Y, Song J, Sun M, Liu X, Liu Z

“…The results of AUC, IDI, and NRI showed that adding these four biomarkers to a model with clinical variables significantly improved predictive value, which was confirmed in the validation cohort.Conclusion: These findings highlight the association of DCA, His, Lys, and Phe with AMI, suggesting their potential role in AMI pathogenesis.Keywords: bile acid, amino acid, unstable angina, acute myocardial infarction, metabolomics…”
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To unionize, or not to unionize? A comparison of integrated plastic surgery residency program benefits by Kerilyn N. Godbe, Ryan Higginbotham, Erin Rauber, Sofia Victoria Corral-Vale, Niaman Nazir, Richard Korentager, Charles C. Jehle

“…Statistical analysis for continuous and discrete variables was performed via Wilcoxon Two-Sample and Fischer exact tests, respectively. …”
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The rat's sciatic nerve functional index dynamics after its transection and recovery by means of epineural neurorrhaphy by Ziia K. Melikov, Volodymyr V. Medvediev

“…The method of determining the function of the paretic limb after sciatic nerve injury in rats using SFI has a number of technical limitations, which are the reason for significant variability in experimental results among different research groups. …”
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Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging by Karienn A. de Souza, Morgan Jackson, Justin Chen, Jocelin Reyes, Judy Muayad, Emma Tran, William Jackson, M. Karen Newell-Rogers, David J. Earnest

“…Results Entrainment of the activity rhythm was stable in all mice on a fixed LD 12:12 cycle but was fully compromised during exposure to shifted LD cycles. Even during “post-treatment” exposure to standard LD 12:12 conditions, re-entrainment in shifted LD mice was marked by altered patterns of entrainment and increased day-to-day variability in activity onset times that persisted into middle-age. …”
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Gender and age effects on the incidence and severity of chemotherapy-induced neuropathic pain: a propensity score matching analysis by Andreas A. Argyriou, Roser Velasco, Foteini Kalofonou, Pantelis Litsardopoulos, Montse Alemany, Dimitrios Rikos, Haralabos P. Kalofonos, Jordi Bruna

“…A Propensity Score Matching Analysis (PSMA) was conducted to create balanced cohorts; accounting for variables that could impact the incidence and severity of CINP in CIPN patients. …”
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Three-dimensional assessment of maxillary arch changes in infants with bilateral cleft lip and palate using vacuum-formed nasoalveolar molding with active screw versus conventional... by Khadega Ali Al-Khateeb, Mai Hamdy Aboulfotouh, Fatma Abdelsayed, Wesam Mohamed, Mohamed Abd-El-Ghafour

“…Sixteen items in the digital maxillary models were analyzed at T1 (pre-NAM therapy) and T2 (post-NAM therapy) using 3D software. Parametric data were analyzed using a repeated measures ANOVA test to compare between groups and assess changes within each group by time, while non-parametric data were analyzed using the Mann–Whitney U test to compare between groups and the Wilcoxon signed-rank test to assess changes within each group by time. …”
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