Estimation of the air conditioning energy consumption of a classroom using machine learning in a tropical climate by Liliana Ortega-Diaz, Julian Jaramillo-Ibarra, German Osma-Pinto

“…Machine learning is the most widely used approach for prediction due to its speed, accuracy, and non-linear modeling. …”
Get full text

Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus. by Li Ou, Steven J Chen, I-Ting Teng, Lijuan Yang, Baoshan Zhang, Tongqing Zhou, Andrea Biju, Cheng Cheng, Wing-Pui Kong, Nicholas C Morano, Erik-Stephane D Stancofski, John-Paul Todd, Yaroslav Tsybovsky, Shuishu Wang, Cheng-Yan Zheng, John R Mascola, Lawrence Shapiro, Ruth A Woodward, Ursula J Buchholz, Peter D Kwong

“…The cryo-EM structure of a triple disulfide-stabilized pre-F trimer with the variable region of antibody MPE8 at 3.25-Å resolution confirmed the formation of designed disulfides and provided structural details on the MPE8 interface. …”
Get full text

Epidemiology of Burden of Prostate Cancer in Iran during 2009-2019: Estimates from the Global Burden of Disease Study 2019 by Elham Goodarzi, Saeed Rajaei Ramesh, Sajjad Rahimi Pordanjani, Mahshid Abbasi, Fazlollah Fathollahi Shoorabeh

“…Background: Prostate cancer (PC) is the second most common cancer in men and the fifth leading cause of death worldwide. …”
Get full text

Comprehensive profiling of Rhodiola rosea roots and corresponding products: phytochemical insights and modulation of neuroinflammation in BV2 microglial cell model by Małgorzata Kołtun-Jasion, Karolina Czerwiec, Andrzej Parzonko, Aleksandra Bakiera, Marcin Ożarowski, Anna Karolina Kiss

“…Misidentification of R. rosea was most frequently observed among tablet and capsule formulations, whereas products in the form of cut raw material exhibited the highest quality. …”
Get full text

Agricultural Innovation Characteristics and Their Utilisation: A Case of National Agricultural Research Organization by Barekye, Alex

“…The study was guided by a conceptual framework which considered agricultural innovation characteristics and market attributes as independent variables and utilization as a dependent variable. …”
Get full text

PROGNOSIS OF RETENTION AND ABNORMAL POSITION OF CANINES by S.I. Doroshenko, O.A. Kaniura, K.V. Storozhenko, S.V. Irkha, D.O. Marchenko, Kh.M. Demianchuk

“…Conducted research has detected that the most objective indicator in the eruption of abnormal eruption of canines is the significant difference in their inclinations with lateral incisors, which serve as the guiding axis of eruption. …”
Get full text

Increased neutrophil counts are associated with poor overall survival in patients with colorectal cancer: a five-year retrospective analysis by Libia Alejandra Garcia-Flores, Libia Alejandra Garcia-Flores, María Teresa Dawid De Vera, Jesus Pilo, Jesus Pilo, Alejandro Rego, Alejandro Rego, Gema Gomez-Casado, Gema Gomez-Casado, Isabel Arranz-Salas, Isabel Hierro Martín, Julia Alcaide, Esperanza Torres, Almudena Ortega-Gomez, Almudena Ortega-Gomez, Almudena Ortega-Gomez, Hatim Boughanem, Hatim Boughanem, Hatim Boughanem, Hatim Boughanem, Hatim Boughanem, Manuel Macias-Gonzalez, Manuel Macias-Gonzalez, Manuel Macias-Gonzalez

“…We observed increased mortality risk in patients in the highest tertile of white blood cells [HR=1.85 (1.09-3.13), p<0.05], neutrophils [HR=1.78 (95% CI: 1.07-2.96), p<0.05], and monocytes [HR=2.11 (95% CI: 1.22-3.63)], compared to the lowest tertile, after adjusting for all clinicopathological variables. Random forest analysis identified neutrophils as the most crucial variable in predicting survival rates, having an AUC of 0.712, considering all clinicopathological variables. …”
Get full text

Expanding the phenotypic and genetic landscape of congenital neutropenia through whole‐exome and genome sequencing by Séverine Marti, Philippe Pellet, Blandine Beaupain, Léa Durix, Julien Buratti, Yves Réguerre, Nathalie Aladjidi, Saba Azarnoush, Severine Clauin, Wahid Abou Chahla, Gilles Blaison, Jeremy Bertand, Damien Bodet, Benoit Brethon, Jessica Chane‐Teng, Manon Delafoy, Chrystelle Dupraz, Virginie Gandemer, Philippe Denizeau, Alice Goldenberg, Pierre Hirsch, Anaïs l'Haridon, Aude Marie‐Cardine, Gabriella Vera, Brigitte Nelken, Laure Nizery, Marie Nolla, Marlène Pasquet, Jérémie Rosain, Louis Terriou, Isabelle Plo, Jean Donadieu, Christine Bellanné‐Chantelot

“…While some CN cases present only with neutropenia, others present with additional extra‐hematological manifestations. The most common cause of CN is variants in ELANE; however, approximately 30 other genes have been implicated. …”
Get full text

Clinical characterization of Collagen XII‐related disease caused by biallelic COL12A1 variants by Riley M. McCarty, Dimah Saade, Pinki Munot, Chamindra G. Laverty, Hailey Pinz, Yaqun Zou, Meghan McAnally, Pomi Yun, Cuixia Tian, Ying Hu, Lucy Feng, Rahul Phadke, Sophia Ceulemans, Pilar Magoulas, Andrew J. Skalsky, Jennifer R. Friedman, Stephen R. Braddock, Sarah B. Neuhaus, Denise M. Malicki, Matthew N. Bainbridge, Shareef Nahas, David P. Dimmock, Stephen F. Kingsmore, Timothy E. Lotze, A. Reghan Foley, Francesco Muntoni, Volker Straub, Sandra Donkervoort, Carsten G. Bönnemann

“…Results All patients presented with a consistent constellation of congenital onset clinical features: hypotonia, dysmorphic features, most notably gingival hypertrophy, prominent distal joint hyperlaxity, with co‐occurring contractures of large joints, and variable muscle involvement, evident both clinically and on muscle imaging. …”
Get full text

Assessing Spatio-Temporal Changes in the Ecological Livability Index (Case Study: Tabriz Metropolis ) by Sajjad Moshiri, Ahmad Nikdel Monavvar, MohammadReza Jebraily, Iraj Teimouri, Khalil Valizadeh Kamran, bakhtiar feizizadeh

“…It is important to note that the final values of the ecological livability index could not be fully understood without considering the direct effects of the variables and their respective weights. For instance, the variable of LST_i = 0.324, which had the highest weight, showed a declining trend and was most concentrated in the central and southern parts of Tabriz. …”
Get full text

The resurgence of religion in international relations: How theories can accommodate it? by Shameer Modongal

“…It concludes that even though existing mainstream theories have not yet considered religion as an influential variable, theoretically, it is viable to accommodate it to the frameworks of these theories…”
Get full text

Analysis of Clinicopathological Characteristics and Treatment Modalities in Multisystem Inflammatory Syndrome in Children: An Eastern Indian Cohort by Purbasha Gupta, Subhojit D Sarkar, Mohini Bhelo, Anurag Mondal, Priyankar Pal

“…Cardiac affection was detected in 57.74%, mostly as myocarditis, and 27% had coronary artery dilatations (CAAs). …”
Get full text

Approach to asthma in adults by Natalie Schellack, A. Truter, P. N. Ntuli

“…Patients suffering from asthma should be aware of its signs and symptoms, as well as factors that can precipitate an asthmatic attack. Asthma is mostly classified as either acute or chronic. The diagnosis of asthma is based on identification of both a characteristic pattern of respiratory symptoms and variable expiratory airflow limitation. …”
Get full text

A Grounded Theory of Political Intelligentizing in Business Administration by Annabel-Mauve Adjognon

“…Business administration is mostly driven by political games between top-level corporate managers. …”
Get full text

Vestibular migraine: diagnosis challenges and need for targeted treatment by Felipe Barbosa, Thaís Rodrigues Villa

“…Vestibular migraine often begins several years after typical migraine and has a variable clinical presentation. In vestibular migraine patients, the neurological and neurotological examination is mostly normal and the diagnosis will be based in the patient clinical history. …”
Get full text

The Effect of Landscape Pattern on Urban Temperature Changes in Hamadan by Marziye Shojaei, Kamran Shayesteh, Behnaz Attaeian

“…Urbanization and urbanized areas have a significant impact on local and global climate. One of the most important its effects is surface urban thermal variations (SUTV), including surface urban heat islands (SUHI) and surface urban heat sinks (SUHS). …”
Get full text

Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study by Grace Irimu, Morris Ogero, George Mbevi, David Gathara, Samuel Akech, Mike English, Jalemba Aluvaala, Ambrose Agweyu, Mercy Chepkirui, Sylvia Omoke, Lucas Malla, Emma Namulala, Juma Vitalis, Rachel Inginia, Grace Ochieng, Lydia Thuranira, Esther Njiru, Charles Nzioki, Caren Emadau, Christine Manyasi, Fred Were, Magdalene Kuria, Mary Waiyego, Beth Maina, Edith Gicheha, Joseph Nganga, Esther Mwangi, Esther Muthiani, Mary Nguri, Samuel Soita, Margaret Waweru, Alfred Wanjau, Caroline Mwangi, John Wainaina, Livingstone Mumelo, Nyumbile Bonface, Wagura Mwangi, Penina Mwangi, Felistus Makokha, Josephine Ojigo, Bernadette Lusweti, Amilia Ngoda, Dolphine Mochache, Jane Mbungu, Joan Baswetty, Josephine Aritho, Beatrice Njambi, Zainab Kioni, Lucy Kinyua, Alice Oguda, Loise N. Mwangi, Nancy Mburu, Celestine Muteshi, Salome Okisa Muyale, Faith Mueni, Rosemary Mututa, Joyce Oketch, Orina Nyakina, Faith Njeru, Margaret Wanjiku Mwaura, Seline Kulubi, Susan Wanjala, Pauline Njeru, John Ollongo, Otieno George Obop, Jeska Kuya, Benjamin Tanui, Judith Onsongo, Peter Muigai, Arnest Namayi

“…Background Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient care. …”
Get full text

Assessing reading fluency in elementary grades: A machine learning approach by Gabriel Candido da Silva, Rodrigo Lins Rodrigues, Américo N. Amorim, Lieny Jeon, Emilia X.S. Albuquerque, Vanessa C. Silva, Vinícius F. da Silva, André L.A. Pinheiro, João P.J.R. Nunes, Suzana X.M.G. de Souza, Maxsuel S. Silva, Igor Mauro, Alexandre Magno Andrade Maciel

“…Ensemble methods such as Gradient Boosting and Random Forest also yielded robust results, particularly in regression analyses where they effectively captured the variability in expert fluency ratings. Notably, reading speed emerged as the most critical indicator of fluency across all experiments, consistently outweighing contributions from accuracy and prosody. …”
Get full text

Accuracy of Predictive Equations for Metabolizable Energy Compared to Energy Content of Foods for Dogs and Cats Estimated by In Vivo Methods in Brazil by Pedro Henrique Marchi, Andressa Rodrigues Amaral, Leonardo de Andrade Príncipe, Larissa Wünsche Risolia, Mariana Fragoso Rentas, Ana Beatriz Fasolai, Rafael Vessecchi Amorim Zafalon, Gabriela Luiza Fagundes Finardi, Juliana Toloi Jeremias, Raquel Silveira Pedreira, Júlio Cesar de Carvalho Balieiro, Thiago Henrique Annibale Vendramini

“…The gold standard method for determining this variable is through feeding trials with the target species. …”
Get full text

Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis by Mohamed A. Kamal, Matthew P. Kosloski, Ching-Ha Lai, Michael A. Partridge, Manoj Rajadhyaksha, Vanaja Kanamaluru, Ashish Bansal, Arsalan Shabbir, Brad Shumel, Marius Ardeleanu, Susan M. Richards, Hong Yan, Christine R. Xu, Ainara Rodríguez-Marco, Jing Xiao, Faisal A. Khokhar, Guy Gherardi, Elisa Babilonia, Jennifer Maloney, Eric Mortensen, Bolanle Akinlade, Ned Braunstein, Neil Stahl, Albert Torri, John D. Davis, A. Thomas DiCioccio

“…High-titer ADAs, while infrequent, were the variable most associated with lower dupilumab concentrations in serum and loss of efficacy, independent of NAb status. …”
Get full text