T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma by Enrico Maggi, Nadine Landolina, Enrico Munari, Francesca Romana Mariotti, Nicola Tumino, Paola Vacca, Bruno Azzarone, Lorenzo Moretta

“…Neuroblastoma (NB) is an immunologically “cold” tumor with poor or no inflamed substrates as most of solid pediatric tumors (SPT). Consistent data indicate that NB tumor microenvironment (TME) is dominated by myeloid cells, with little (but variable) T cell infiltration. …”
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Organic petrographical, geochemical, and mineralogical features of the Permian Coalbrook Sub-basin, South Africa: Reconstruction of paleo-depositional conditions by F. Zonke Chitlango, Ofentse M. Moroeng, Nicola J. Wagner

“…The samples are classified as low-rank A sub-bituminous to medium-rank D bituminous, with variable maceral composition, with very low to moderate vitrinite (5.8–48.0 vol%, mineral matter free basis, mmf) although most samples are dominated by inertinite (from 42.0 to 90.6 vol%, mmf). …”
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Levothyroxine Timing during Ramadan: A Randomized Clinical Trial by Moeber Mahzari, Fahad Al Remthi, Ibrahim Ajwah, Mohammed Al Hazmi, Wesam Moafa, Awad Al Shahrani, Sameerah Al Shehri, Motasim Badri

“…Hypothyroidism requires lifelong thyroid hormone replacement with levothyroxine. For most hypothyroid patients fasting during Ramadan, compliance with the administration procedure is a challenge. …”
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Cavernoma gigante: relato de dois casos Giant cavernous angioma: report of two cases by Guilherme Cabral de Andrade, Mirto Nelso Prandini, Fernando Menezes Braga

“…They can occur at any age, including the neonatal period. Most of the small lesions are located inside the brain parenchyma. …”
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Altered lower leg muscle activation patterns in patients with cerebral palsy during cycling on an ergometer by Alves-Pinto A, Blumenstein T, Turova V, Lampe R

“…Ana Alves-Pinto,1,* Tobias Blumenstein,1,* Varvara Turova,1 Renée Lampe1,2 1Research Unit of the Buhl-Strohmaier Foundation for Cerebral Palsy and Paediatric Neuroorthopaedics, Orthopaedic Department, Klinikum rechts der Isar, 2Markus Würth Professorship, Technical University of Munich, Munich, Germany *These authors contributed equally to this work Objective: Cycling on a recumbent ergometer constitutes one of the most popular rehabilitation exercises in cerebral palsy (CP). …”
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A Clinical and Pathological Comparison of Different Immunomorphological Subvariants of Nodular Lymphocyte-Predominant Hodgkin’s Lymphoma at Initial Diagnosis by IA Shupletsova, AM Kovrigina, TN Moiseeva, EI Dorokhina, SM Kulikov

“…Nodular lymphocyte-predominant Hodgkin’s lymphoma (NLPHL) is a rare Hodgkin’s lymphoma subtype with a variable growth pattern and immune tissue architecture of tumor. …”
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Genotype‐By‐Environment Interaction and Yield Stability of Kabuli Chickpea (Cicer arietinum L.) in Northern Ethiopia by Alemnesh Eskezia, Kelemu Nakachew, Meseret Tadesse, Mulusew Kassa

“…After peas and beans, it is the most important legume in the world. Reduced chickpea production and productivity have been significantly influenced by the lack of improved and adaptable genotypes, poor management practices, biotic factors such as disease and pests, and abiotic factors including fluctuating rainfall and temperature. …”
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Reduction of monoclonal antibody viscosity using interpretable machine learning by Emily K. Makowski, Hsin-Ting Chen, Tiexin Wang, Lina Wu, Jie Huang, Marissa Mock, Patrick Underhill, Emma Pelegri-O’Day, Erick Maglalang, Dwight Winters, Peter M. Tessier

“…Of the three features, most predicted antibodies at risk for high viscosity, including antibodies with diverse antibody germlines in our study (79 mAbs) as well as clinical-stage IgG1s (94 mAbs), are those with low Fv isoelectric points (Fv pIs < 6.3). …”
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Performance Analysis of Fractionalized Order PID Controller-based on Metaheuristic Optimisation Algorithms for Vehicle Cruise Control Systems by Abdelhakim Idir, Abderrahim Zemmit, Khatir Khettab, Mokhtar Nesri, Sifelislam Guedida, Laurent Canale

“…The motion of vehicles is inherently complex and variable, leading to significant non-linearity within the cruise control system (CCS). …”
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SOCİO-ECONOMİC AND OPERATİONAL DYNAMİCS OF REAPER-THRESHER OWNERSHİP İN ADANA, TÜRKIYE by Şinasi AKDEMIR, Ufuk GÜLTEKIN, Kasım Eren TUNA, Issaka Saidou ISMAILLA, Aziz MAVRUK, Hüseyin ÖZBEK

“…The explanation rate of these variables for the dependent variable (R square) is 99.3%. …”
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A Nanostring gene expression approach identifies aggressive clinical behavior related genes in dedifferentiated liposarcoma by Francesca Zalfa, Paolo Manca, Simone Carotti, Silvia Vallese, Daniela Righi, Chiara Taffon, Lorenzo Nibid, Marta Sbaraglia, Carla Rabitti, Francesco Pantano, Giuseppe Tonini, Angelo Paolo Dei Tos, Bruno Vincenzi, Giuseppe Perrone

“…Abstract Dedifferentiated liposarcoma (DDLPS) is one of the most common subtypes of soft tissue sarcoma with a highly variable clinical behavior. …”
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Effect of inappropriate solid waste on microplastic contamination in Balasore district and its aquatic environment by Arun Kumar Mohanta, Chittaranjan Sahoo, Rajkumar Jena, Sthitaprajna Sahoo, Sunil Kumar Bishoyi, Biswajit Patra, Soumya Ranjan Dash, Biswajita Pradhan

“…Abstract Background Microplastic infection is now one of the world’s key environmental concerns. The most significant causes of microplastic contamination in aquatic ecosystems are coastal villages, coastal landfill sites, shipping activities and coastal dumping areas. …”
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Analytical validation of a flow cytometric method for the detection and quantification of canine mast cells in peripheral blood, bone marrow, and lymph node by Giulia Iamone, Fulvio Riondato, Rachel Hanford, Amandine Lejeune, Amir Kol

“…Mast cell tumors (MCTs) are the most common skin neoplasms in dogs and exhibit highly variable biological behavior. …”
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Predicting Red Blood Cell Transfusion in Elective Cardiac Surgery: A Machine Learning Approach by Beatriz Lau, Daniel Ramos, Vera Afreixo, Luís M. Silva, Ana Helena Tavares, Miguel Martins Felgueiras, Diana Castro Paupério, João Firmino-Machado

“…An analysis of Shapley additive explanations values revealed that the most important variable was preoperative haemoglobin levels, which can be optimised through the Patient Blood Management approach. …”
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Immunohistochemical expression of parathyroid hormone-related protein and ezrin in invasive breast carcinoma of no special type: a retrospective analysis by Menna Allah Gamil Ali Shalaby, Marwa Mohammed Dawoud, Marwa Salah Gadallah, Asmaa Gaber Abdou

“…Abstract Background Globally, breast cancer ranks among the most common malignancies and has a high mortality rate. …”
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Morphological and Morphometric Analysis of Pterion: A Cross-sectional Study from Eastern India by Phalguni Srimani, Mithu Paul, Shukchand Hansda

“…Conclusion: The morphology and morphometric evaluation of the pterion are highly variable, which can have significant implications in the fields of anthropology, forensic medicine and neurosurgery.…”
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Levels and Predictors of Knowledge, Attitudes, and Practices Regarding Contraception Among Female TV Studies Undergraduates in Nigeria: Cross-Sectional Study by Hadizah Abigail Agbo, Philip Adewale Adeoye, Danjuma Ropzak Yilzung, Jawa Samson Mangut, Paul Friday Ogbada

“…The primary outcome variable was the practices regarding contraception, while attitude and knowledge were secondary outcome variables, with sociodemographics as covariates. …”
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Comprehensive Probabilistic Analysis and Practical Implications of Rainfall Distribution in Pakistan by Fahad Haseeb, Shahid Ali, Naveed Ahmed, Nassir Alarifi, Youssef M. Youssef

“…Nine probability distributions were assessed, with five models—log Pearson type-III (LP3), Weibull (W2), log normal (LN2), Generalized Extreme Value (GEV), and gamma (GAM)—deemed most suitable for the region’s climatic variability. …”
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Challenges and future prospects of online practical education in physical education faculties during the COVID-19 pandemic by O.M. Abdel Fattah, A.A. Zureigat, S.H. Qasim, M.A. Alzughailat, A.S. Khasawneh

“…In addition, there are statistically significant differ­ences in the level of challenges according to the gender variable. From the students’ points of view, the content and the educational environment are among the most significant challenges they face during online practical education.Scientific novelty. …”
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Prevalence of depression in elderly and relations to chronic diseases by Gajović Gordana, Kocić Sanja, Radovanović Snežana, Simić-Vukomanović Ivana, Janićijević Katarina, Radević Svetlana

“…Background/Aim. Depression is the most prevalent mental disorder which affects approximately 7% of the world’s older population. …”
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