Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 scre... by Nicole Lowres, Jake Olivier, Tze-Fan Chao, Shih-Ann Chen, Yi Chen, Axel Diederichsen, David A Fitzmaurice, Juan Jose Gomez-Doblas, Joseph Harbison, Jeff S Healey, F D Richard Hobbs, Femke Kaasenbrood, William Keen, Vivian W Lee, Jes S Lindholt, Gregory Y H Lip, Georges H Mairesse, Jonathan Mant, Julie W Martin, Enrique Martín-Rioboó, David D McManus, Javier Muñiz, Thomas Münzel, Juliet Nakamya, Lis Neubeck, Jessica J Orchard, Luis Ángel Pérula de Torres, Marco Proietti, F Russell Quinn, Andrea K Roalfe, Roopinder K Sandhu, Renate B Schnabel, Breda Smyth, Apurv Soni, Robert Tieleman, Jiguang Wang, Philipp S Wild, Bryan P Yan, Ben Freedman

“…Nineteen studies (14 countries from a mix of low- to middle- and high-income countries) collaborated, with 141,220 participants screened and 1,539 new AF cases. …”
Get full text

Clinical efficacy and safety of sodium-glucose cotransporter protein-2 (SGLT-2) inhibitor, glucagon-like peptide-1 (GLP-1) receptor agonist, and Finerenone in type 2 diabetes melli... by Jingyi Guo, Maoying Wei, Wenhua Zhang, Yijia Jiang, Aijing Li, Churan Wang, Dan Yin, Anning Sun, Yanbing Gong

“…Traditional meta-analysis of variables was conducted using Stata 17.0 software with a random-effects model. …”
Get full text

A Radiogenomic Deep Ensemble Learning Model for Identifying Radionecrosis Following Brain Metastases (BM) Stereotactic Radiosurgery in Patients With Non-small Cell Lung Cancer BM by Jingtong Zhao, MS, Eugene Vaios, MD, MBA, Evan Calabrese, MD, PhD, Zhenyu Yang, PhD, Scott Robertson, PhD, John Ginn, PhD, Ke Lu, PhD, Fang-Fang Yin, PhD, Zachary Reitman, MD, PhD, John Kirkpatrick, MD, PhD, Scott Floyd, MD, PhD, Peter Fecci, MD, PhD, Chunhao Wang, PhD

“…We employed our positional encoding method to optimally fuse the low-dimensional clinical/genomic features with the high-dimensional image features. …”
Get full text

Challenges of integrating HIV prevention and treatment in China's border mountain regions: a grounded theory study by Sixian Du, Haoran Niu, Feng Jiang, Liwen Gong, Shan Zheng, Qi Cui, Xu Yang, Jiayan He, Rongcai Dai, Qilian Luo, Yiqing Yang

“…In integration of HIV prevention and treatment, major issues involved low referral rates, loose inter-agency cooperation, and systemic barriers to integration. …”
Get full text

Identifying bellwether sewershed sites for sustainable disease surveillance in Bengaluru, India: a longitudinal studyResearch in context by Rebecca Fern Daniel, Subash K. Kannan, Namrta Daroch, Sutharsan Ganesan, Farhina Mozaffer, Vishwanath Srikantaiah, Lingadahalli Subrahmanya Shashidhara, Rakesh Mishra, Farah Ishtiaq

“…In a post-pandemic world, particularly in low-resource settings, focusing on the best-performing sewershed sites will ensure high-quality data that captures valid signals amid the noise from wastewater, conserves resources, and optimises public health actions beyond SARS-CoV-2. …”
Get full text

Effects of two forms of school-based high-intensity interval training on body fat, blood pressure, and cardiorespiratory fitness in adolescents: randomized control trial with eight... by Jarosław Domaradzki, Marek Popowczak, Katarzyna Kochan-Jacheć, Paweł Szkudlarek, Eugenia Murawska-Ciałowicz, Dawid Koźlenia

“…Although these effects were small (low eta values), post hoc tests (all comparisons in post-intervention, p > 0.05) showed that both the HIIT and HIPT groups exhibited beneficial changes compared to controls; however, no statistically significant differences were observed between the experimental and control groups. …”
Get full text

Colonization of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci and its associated factors in cancer patients at the University of Gondar Comprehen... by Eden Getaneh Mekonnen, Abebe Birhanu, Mulugeta Yimer, Segenet Bizuneh, Mucheye Gizachew, Baye Gelaw

“…Significant associations were identified between methicillin-resistant Staphylococcus aureus colonization and low absolute neutrophil count (AOR =  13.050, 95% CI: 1.362-125.00, P =  0.026), and between vancomycin-resistant Enterococci colonization and having undergone an invasive procedure (AOR =  8.648, 95% CI: 1.870-39.992, P =  0.006).…”
Get full text

Correlation of plasma insulin-like factor 6 level with risk of acute aortic syndrome and adverse prognosis by DONG Wang, DONG Wang, WANG Ying, ZHANG Mingle

“…Kaplan-Meier curve analysis demonstrated that AAS patients with low INSL6 level had significantly lower cumulative survival rates (P=0.020) and event-free survival rates (P=0.004) than those with high INSL6 level (P<0.05). …”
Get full text

The quality of life of children with heart disease in Tanzania: a single center study by Joëlle R. Koster, Naizihijwa G. Majani, Zawadi E. Kalezi, Johanna W. Hoefnagels, Nuru Letara, Deogratias Nkya, Stella Mongela, Godwin Sharau, Sulende Kubhoja, Vivienne Mlawi, Pilly Chillo, Martijn G. Slieker, Diederick E. Grobbee, Mohamed Janabi

“…Clinical and sociodemographic variables (scored 0 to 1, resp. poorest to highest) were collected. …”
Get full text

Ozone source attribution in polluted European areas during summer 2017 as simulated with MECO(n) by M. Kilian, V. Grewe, V. Grewe, P. Jöckel, A. Kerkweg, M. Mertens, A. Zahn, H. Ziereis

“…Inter-comparisons of results for 2018 and with a coarser model resolution (50 instead of 12 km) show that these results are robust with respect to inter-annual variability and model resolution. Comparing our results with results from other source attribution methods we find that the contributions to ozone from individual sectors, which have large NO<span class="inline-formula">_<i>x</i></span> but rather low VOC emissions, are estimated to be lower, if their emissions of NO<span class="inline-formula">_<i>x</i></span> and VOCs are regarded concurrently.…”
Get full text

Soil-transmitted helminth infection, loss of education and cognitive impairment in school-aged children: A systematic review and meta-analysis. by Noel Pabalan, Eloisa Singian, Lani Tabangay, Hamdi Jarjanazi, Michael J Boivin, Amara E Ezeamama

“…STH-related deficits in school attendance and scholastic achievement was noted in low (SMD:-0.57, P = 0.05) and high ROB strata respectively.…”
Get full text

Characteristics of Surface Soil Moisture Drydown in the Heihe River Basin by Shiyu DONG, Zhongli ZHU, Ziwei XU, Shaomin LIU, Linna CHAI

“…The process of soil drying is referred to as soil moisture drydown.It usually occurs after precipitation， especially for surface soil， and we address this process in three dominant regimes： gravity drainage， energy-limited regime and water-limited regime.The Heihe River Basin originates from the Qilian Mountains， and the landscape zonality here is clear from its upstream， midstream and downstream.By exploring the characteristics of surface soil moisture drydown in this area， researchers were able to understand the patterns and factors associated with soil evaporation under different conditions.The soil drydown events were investigated using data on soil moisture， soil temperature， and air temperature collected between 2016 and 2020 from 10 meteorological observation stations located in the Heihe River Basin.The relationships between soil moisture （SM）， potential evaporation （PE）， the normalized difference vegetation index （NDVI）， soil texture and surface soil drying rates were explored.Using the exponential model for fitting drydown events， the seasonal variation of the drying rate at each site was compared.Results showed that： （1） There were 362 effective drydown episodes between 2016 and 2020， totaling 3584 days.After entering the drydown stage， as the soil gradually became dry， the drying rate also slowed down and became stable after 12 days.The upstream site settled around 0.04 cm3·cm-3·day-1， whereas the middle and downstream sites tended to 0.（2） In upstream， midstream， and downstream， the values of surface soil moisture evaporation efficiency （90%） are lower than 0.25， 0.15， and 0.12， respectively， which can only partially meet atmospheric demand.The evaporation efficiency may be close to 1 if the evapotranspiration of soil profiles below 5 cm is taken into account.（3） Because the surface soil in upstream locations of the Heihe River is relatively wet， the soil drydown process is limited by the atmosphere.The middle and lower reaches of the Heihe River are drier and limited by water.As for the surface soil evaporation rate， the upstream was mainly affected by atmospheric water demand； it increases along with PE.When SM exceeded 0.4 cm3·cm-3， PE and SM had no significant impact on soil drying rate.In the middle and downstream of the Heihe River， the soil evaporation rate increases with SM.In comparison to upstream， the impact of PE on soil evaporation rate is less significant.（4） The type of vegetation and the dry and wet states of the soil both affect how quickly the surface SM dries； the drying rate is very slightly influenced by soil texture.（5） The drydown events fitted by the exponential model have distinct season features.The highest drying rate （τ）， the highest drying range （A）， and the lowest lower limit of soil moisture （θw） were observed in summer.As for desert region， θw is more affected by precipitation and is higher in the summer.For the entire basin， the drying rate of surface soil moisture from high to low was summer， spring， autumn， and the seasonal variability of drying rate increased with the change in surface coverage （meadow， farmland， shrub）.…”
Get full text

Understanding the mechanisms of hydrolytic enzyme mediated organic matter decomposition under different land covers within a subtropical preserve by Suraj Melkani, Noel Manirakiza, Abul Rabbany, Natalia Medina-Irizarry, Samuel Smidt, Anna Braswell, Anna Braswell, Willm Martens-Habbena, Jehangir H. Bhadha

“…Among ecosystems, βG and β-NAG showed seasonal variability, with β-NAG consistently higher in A-Upland Forests, B-Range Areas, and C-Shrub. …”
Get full text

Pre-operative T-stage discrimination in gallbladder cancer using machine learning and DeepSeek-R1 by Joongwon Chae, Zhenyu Wang, Duanpo Wu, Lian Zhang, Alexander Tuzikov, Magrupov Talat Madiyevich, Min Xu, Dongmei Yu, Peiwu Qin

“…Without SMOTE, individual models such as XGBoost achieved an AUROC of 0.508 on the independent test set, while recall for the T1 class remained low (e.g., 14.3% for some models), indicating performance near random chance. …”
Get full text

Artificial intelligence in hospital infection prevention: an integrative review by Rabie Adel El Arab, Zainab Almoosa, May Alkhunaizi, May Alkhunaizi, Fuad H. Abuadas, Joel Somerville, Joel Somerville

“…Innovations in non-real-time AI frameworks offer viable solutions for scaling AI applications in low- and middle-income countries (LMICs), addressing the higher prevalence of HAIs in these regions.ConclusionsArtificial Intelligence stands as a transformative tool in the fight against hospital-acquired infections, offering advanced solutions for prevention, surveillance, and management. …”
Get full text

Assessment of Sleep Quality and Its Determinants Among Patients with Type 2 Diabetes Mellitus in Mogadishu, Somalia: A Cross-Sectional Study by Mohamed NA, Haji Mohamud RY, Hilowle FH, Ali TA, Mohamed YA, Gabow AA, Mohamed HN, Sidow NO, Hassan MS, Waberi MM

“…Multivariable analysis identified several significant predictors, including female gender, unemployment, low income, substance use, physical inactivity, and depressive symptoms. …”
Get full text

The Assessment of Importance - Performance of Dimensions and the Indices of Integrated Tourism Management in Mazandaran Province Beaches by Esmaeil Ghaderi, Gholamreza kazemian, Fatemeh Bagheri

“…These are: “governmental-political integration”, “legal context in organizing phase” (in the third quarter named: low priority) and “ICT”, “legal context in monitoring phase”, “legal context in planning phase”, ”access to the facilities and resources” (in the fourth quarter named: possible overkill). …”
Get full text

Analyzing the impact of area of interest (AOI) size and endmember selection on evapotranspiration (ET) estimation through a contextual model (SEBAL) by Hamza Barguache, Jamal Ezzahar, Jamal Elfarkh, Said Khabba, Salah Er-Raki, Valerie Le Dantec, Mohamed Hakim Kharrou, Ghizlane Aouade, Abdelghani Chehbouni

“…Conversely, applying a shapefile that covers the entire Landsat imagery led to a more uniform distribution of latent heat flux, especially in winter/spring (when the climatic demand is low), which reduced the model’s ability to capture spatial variability. …”
Get full text

Mediating role of psychological resilience between depression and humoral immunological biomarkers in medical staff by Yunyun MA, Yanshuan WEI, Lili QIAN, Xiufeng ZUO, Dechao WANG, Shanfa YU

“…ResultsThe M (P25, P75) score of psychological resilience was 65.50 (53.25, 75.00) in the participating medical staff. The ratios of low, medium, and high levels of psychological resilience were 2.78% (3/108), 51.85% (56/108), and 45.37% (49/108), respectively. …”
Get full text

The efficacy and safety of ketorolac for postoperative pain management in lumbar spine surgery: a meta-analysis of randomized controlled trials by Jianbin Guan, Ningning Feng, Kaitan Yang, Haimiti Abudouaini, Peng Liu

“…In the 12–24-h period, Ketorolac continued to show significant pain reduction (MD =  − 0.48; 95% CI: − 0.68 to − 0.28; P < 0.0001), but this reduction was also below the MCID. Heterogeneity was low in the 12–24-h period (I2 = 13%), indicating consistent results across studies. …”
Get full text