Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms by Marianne Bachmann Salvy, Luca Santuari, Emanuel Schmid-Siegert, Nikolaos Lykoskoufis, Ioannis Xenarios, Bulak Arpat

“…With its versatile and standalone functionality, we anticipate that the implementation of Seq2scFv tools in antibody discovery pipelines will efficiently expedite the full characterization of display libraries and potentially facilitate the identification of high-affinity antibody candidates.…”
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An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli by Irina Kalita, Ira Alexandra Iosub, Lorna McLaren, Louise Goossens, Sander Granneman, Meriem El Karoui

“…This fine-tuning Hfq-mediated mechanism might have the underlying physiological function of maintaining RecB protein levels within an optimal range.…”
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THE MODEL OF DECISION SUPPORT IN CENTRALIZED HEATING MANAGEMENT ON THE CONSUMER SIDE by Yuliia Parfenenko

“…On the basis of the expert survey, the term sets of linguistic variables of the model of fuzzy logic decision making in managing heat supply modes were determined, membership functions of each linguistic variable of the model and rules of logical deduction were developed. …”
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Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. by Keiko Miyadera, Ian Brierley, Jesús Aguirre-Hernández, Cathryn S Mellersh, David R Sargan

“…Variable polyA(n) length was confirmed in DNA from different RPGRIP1(-/-) dogs, yet polyA(n) variability did not correspond with the clinical phenotypes and no individual was found that carried a polyA(n) tract capable of encoding an in-frame variant. …”
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Impact of Product, Process, Organisational, and Marketing Innovation on Micro, Small and Medium Scale Enterprises' Sustainability by Erna Listyaningsih, Yuliansyah Yuliansyah, Rissa A. Martinouva, Febrianty Febrianty, Muazza Muazza, Shofia Amin, Etty Puji Lestari, Amirul Mukminin

“…Objective: This study aimed to investigate how innovation, sustainability, and performance function as moderators in Micro, Small, and Medium-Scale Enterprises (MSMES). …”
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An Analysis of Influential Factors in the Use of Public Bicycles in Tehran by Ehsan Faghihi, Mojtaba Rafieian

“…So far, many researches have been conducted on the components affecting the functional stability of the shared bicycles system, for example Si et al. in 2020 found that factors of efficiency, economic benefits, environmental awareness, and infrastructure incentives influence the willingness to use the shared bicycle system. …”
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Interpretable machine learning for predicting isolated basal septal hypertrophy. by Lei Gao, Boyan Tian, Qiqi Jia, Xingyu He, Guannan Zhao, Yueheng Wang

“…This is a common echocardiographic finding with a prevalence of approximately 7-20%, which may indicate early structural and functional remodeling of the left ventricle in certain pathologies. …”
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Predicting biogas production in real scale anaerobic digester under dynamic conditions with machine learning approach by M. Erdem Isenkul, Sevgi Güneş-Durak, Yasemin Poyraz Kocak, İnci Pir, Mertol Tüfekci, Güler Türkoğlu Demirkol, Selçuk Sevgen, Aslı Seyhan Çığgın, Neşe Tüfekci

“…In recent years, the use of machine learning techniques (ML) has become widespread for analysing the effects of operational factors on anaerobic digestion efficiency. Among these, Support Vector Regression (SVR) with a Radial Basis Function (RBF) kernel has been used to predict biogas yield based on diverse operating parameters. …”
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Economic and environmental power dispatch for energy management systems applied to microgrids with wind energy resources and battery energy storage systems by Jhon Montano, John E. Candelo-Becerra, Cristian Escudero-Quintero, Juan Pablo Guzmán

“…The results show that the approach ensures technical efficiency while minimizing economic and environmental requirements. …”
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Comparative Study on the Treatment Effect of Stretching and High-frequency Diathermy in Subjects With Gastrocnemius Tightness by Beom-Seop Kim, Yixin Wang, Ye-Jin Kim, Min-Young Kim, Hye-Seon Jeon

“…Background: Ankle flexibility is important for maintaining proper biomechanical function. Static stretching is used to improve flexibility with minimal risk; however, its effects are often temporary. …”

Cultivares de trigo submetidas a déficit hídrico no início do florescimento, em casa de vegetação Wheat cultivars submitted to water deficit at the beginning of flowering in greenh... by Diego dos Santos, Vandeir F. Guimarães, Jeferson Klein, Samuel L. Fioreze, Eurides K. Macedo Júnior

“…Reduction was found in the gravimetric soil moisture, in the relative levels of water and in all biometric variables, in function of the water deficit. The grain production showed difference only among the water regimes, in which the cultivar CD 111 is more efficient in the maintenance of the productive potential in conditions of water deficit, through the quick recovery in the relative content of water in leaves.…”
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Respiratory Muscle Strength as a Predictor of VO2max and Aerobic Endurance in Competitive Athletes by Gökhan Deliceoğlu, Banu Kabak, Veli O. Çakır, Halil İbrahim Ceylan, Muntean Raul-Ioan, Dan Iulian Alexe, Valentina Stefanica

“…These findings suggest that respiratory muscle strength plays a more substantial role in determining VO₂max in individuals with higher ventilatory efficiency, highlighting the importance of both respiratory strength and breathing efficiency in aerobic performance. …”
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Application of multi-objective neural network algorithm in industrial polymerization reactors for reducing energy cost and maximising productivity by Fakhrony Sholahudin Rohman, Sharifah Rafidah Wan Alwi, Dinie Muhammad, Ashraf Azmi, Zainuddin Abd Manan, Jeng Shiun Lim, Hong An Er, Siti Nor Azreen Ahmad Termizi

“…Optimization on an industrial scale is a complex task that involves fine-tuning the performance of large-scale systems and applications to make them more efficient and effective. This process can be challenging due to the increasing volume of work, growing system complexity, and the need to maintain optimal performance. …”
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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Model of the Connecting Optimal Number of Heat Consumers by Sergey M. Terekhov, Vladimir A. Nemtinov, Kirill S. Kornilov

“…The economic status of all participants in the heat supply process depends on the efficiency of the functioning of the heat supply systems. …”
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The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass by Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément

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Landing scheduling for carrier aircraft fleet considering bolting probability and aerial refueling by Genlai Zhang, Lei Wang, Zhilong Deng, Xuanbo Liu, Xichao Su, Haixu Li, Chen Lu, Kai Liu, Xinwei Wang

“…Then, taking the landing sequencing as decision variables, a combinatorial optimization model with a compound objective function is formulated. …”
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Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Methods‍　‍The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
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A Hybrid RBF-PSO Framework for Real-Time Temperature Field Prediction and Hydration Heat Parameter Inversion in Mass Concrete Structures by Shi Zheng, Lifen Lin, Wufeng Mao, Yanhong Wang, Jinsong Liu, Yili Yuan

“…These findings guided a phased optimization strategy, as follows: prioritizing high-precision calibration of dominant parameters while relaxing constraints on low-sensitivity variables, thereby balancing accuracy and computational efficiency. …”
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Optimization Design of the Transmission System of Small-size Shrub Brush Cutter based on MATLAB by Yang Chunmei, Guo Minghui, Ma Yan, Liu Qianjun, Yang Tie

“…By determining the objective function of the transmission system,selecting the independent design variables,determining the constraints,the mathematical model of transmission system is established.The analysis and optimization of the design variables,objective function and the boundary conditions are carried out,the complex method optimization program of MATLAB is written,and by using its powerful ability of optimization design to optimize the transmission system of the brush cutter. …”
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