Genetically surface-modified Escherichia coli outer membrane vesicles targeting MUC1 antigen in cancer cells by Sedthawut Laotee, Wanatchaporn Arunmanee

“…In conclusion, this rapid and efficient bio-ligation system facilitates the display of functional scFv on OMV surfaces, offering a promising approach for targeted delivery to MUC1-expressing cancer cells.…”
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Deterministic Calculation Method for Continuous-energy Neutron Transport Equation in No-resonance Energy-range by LIU Haopo, LI Yunzhao, WU Hongchun, CAO Liangzhi

“…In order to eliminate the multi-group approximation in the deterministic method, a method for calculating neutron transport equation in the non-resonant energy region based on function expansion was proposed. Initially, the non-resonant energy region was subdivided into segments, and within each segment, orthogonal polynomials serve as base functions for expanding the neutron flux density, which realized the processing of single energy independent variable in the neutron flight and absorption process, as well as the handling of double energy independent variable in the neutron scattering process. …”

Different whole body HIIT protocols do not promote different muscle thickness and functional adaptations among healthy physically active subjects by Alexandre L. Evangelista, Júlio B. B. de Camargo, Roberta L. Rica, Luiz Carlos Carnevali Júnior, Gregg S. Mallett, Valentina Bullo, Marco Bergamin, Stefano Gobbo, Danilo S. Bocalini

“…Morphological (ultrasound-derived muscle thickness of the vastus lateralis [MTVL]) and general fitness (muscle endurance and maximal oxygen consumption) assessments were performed at pre- and post-intervention moments.ResultsBoth training protocols elicited significant improvements in all dependent variables (p < 0.05), with no significant between-group differences.ConclusionRegardless of the training configuration, both WB-HIIT programs serve as time-efficient strategies to induce changes in muscle thickness of the vastus lateralis and functional adaptations in healthy, physically active young individuals.…”
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Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and intervention by Giulia Marafioti, Laura Culicetto, Desirèe Latella, Angela Marra, Angelo Quartarone, Viviana Lo Buono

“…Dynamic functional connectivity studies report reduced brain activity efficiency, while graph theory analyses show decreased network integration. …”
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Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke by XIE Qiurong, LIN Wanqi, ZHANG Qi, SHENG Bo, ZHANG Yanxin, HUANG Jia

“…Automated assessment of upper extremity motor function based on machine learning algorithms with markerless sensing techniques has focused on the Fugl-Meyer assessment of upper extremity (FMA-UE), Brunnstrom stages, and Wolf motor function test (WMFT) scales and has been proved with high-scoring accuracy and time efficiency. …”
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MULTI-OBJECTIVE OPTIMIZATION DESIGN FOR CUTTING MECHANISM OF ROADHEADER BASED ON IMPROVED GENETIC ALGORITHM by MAO Jun, PAN DeWen, XIE Miao, ZHENG GuangHui

“…The comprehensive performance of cutting mechanism of roadheader is decided by cutting dust,quantity of pick consumption,specific density consumption,load fluctuation and production efficiency. This paper takes motion parameters and structure parameters of cutting mechanism for design variables and optimizes multi-objective function of comprehensive performance of cutting mechanism based on the improved genetic algorithm. …”
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Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. by Maila Giannandrea, Fabrizia C Guarnieri, Niels H Gehring, Elena Monzani, Fabio Benfenati, Andreas E Kulozik, Flavia Valtorta

“…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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Direct methanol fuel cells parameter identification with enhanced algorithmic technique by Manish Kumar Singla, Muhammed Ali S.A, Ramesh Kumar, Hamed Zeinoddini-Meymand, Farhad Shahnia

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Influence of heavy oil components and optimal magnetic nanocatalysts on the heavy oil upgrading by microwave-assisted by Parya Torkaman, Ramin Karimzadeh, Arezou Jafari

“…It indicates a slight loss in efficiency due to aggregation or degradation.…”
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Statistical learning-driven parameter tuning in injection molding using modified simplex method by Pongchanun Luangpaiboon, Walailak Atthirawong, Anucha Hirunwat, Pasura Aungkulanon

“…The Taguchi design of experiments and desirability function analysis were employed to establish a baseline. …”
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Transient decline and early recovery of noninvasive myocardial work after kidney transplantation: a prospective study by Yulin Huang, Lin Jin, Xinyan Qiu, Canying Yang, Luyi Ping, Zhengyao Jiang, Hua Zou, Zhihong Zhang, Jiwei Wang

“…NIMW parameters include global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE).Results 1) Renal function indicators, including blood urea nitrogen, serum creatinine, and estimated glomerular filtration rate improved significantly at 10 days post-KT. …”
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Optimizing a Bayesian Method for Estimating the Hurst Exponent in Behavioral Sciences by Madhur Mangalam, Taylor J. Wilson, Joel H. Sommerfeld, Aaron D. Likens

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Pectin extraction from cocoa husk of different genotypes and stages of ripeness by Enrique Arévalo-Gardini, Cesar Oswaldo Arévalo-Hernández, Virupax Baligar, Dapeng Zhang

“…Results showed that genotype and ripeness significantly affect extraction efficiency and pectin functionality. The highest pectin yield was 77.7% for IMC-67 (ripe) and 72.6% for CCN51 (semi-ripe) at optimal conditions (pH 1.5–1.6, 80 °C, 75 minutes). …”
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Optimal ANOVA-Based Emulators of Models With(out) Derivatives by Matieyendou Lamboni

“…Our emulators are also competitive in dealing with different distributions of the input variables and selecting inputs and interactions. Simulations show the efficiency of our approach.…”
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West Nile Virus Vaccine Design by T Cell Epitope Selection: In Silico Analysis of Conservation, Functional Cross-Reactivity with the Human Genome, and Population Coverage by Frances M. Waller, Pedro A. Reche, Darren R. Flower

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STRUCTURAL RELIABILITY OPTIMIZATION DESIGN OF REINFORCED SHELL MODEL BASED ON ADAPTIVE SURROGATE MODEL by LIU YuZhuo, CAO LiXiong, WU JianGuo, LI HaiBo

“…Reinforced shell structure is widely used in aerospace load-bearing structures because its high specific stiffness and specific strength.By considering the uncertainty and risk factors in the structural parameters，the Reliability-Based Design Optimization （RBDO） can avoid the overly conservative design of the structure and ensure its reliability and safety.An efficient RBDO method based on adaptive agent model was proposed.This method solves the problem of lightweight design of reinforced shell structure under buckling reliability constraints.The adaptive addition of sample points was implemented through the expected feasibility function criterion，and the discrete variables was continued by constructing piecewise functions.This increases optimization efficiency while ensuring the reliability of design results.Finally，the effectiveness of the proposed method is verified by comparing the RBDO results with the deterministic optimization results.…”
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Vehicle detection method based on multi-layer selective feature for UAV aerial images by Yinbao Ma, Yuyu Meng, Jiuyuan Huo

“…However, this task remains challenging due to variable high-altitude viewpoints, complex environmental interference, and limitations in algorithmic efficiency. …”
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Carpal tunnel release surgery restores force control but not force coordination in CTS patients by Thomas Jacob, Mohamed Ibrahim, G. Vishnu Babu, K. Shyamnath Krishna Pandian, R. Krishnamoorthy, G. Karthikeyan, P. Jeyakumar, V. S. Valarmathy, Jahir Hussain, C. S. Ezhilavan, K. Sridhar, Sivakumar Balasubramanian, S. K. M. Varadhan

“…Abstract Efficient manipulation of objects is crucial for daily interactions with the world. …”
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Multiobjective optimization of Murta (Ugni molinae Turcz) juice lactic acid fermentation with monocultures and cocultures of Lactobacillus acidophilus and Lactiplantibacillus plant... by C.J. Gomes-Lobo, R. Luna, A. Rodríguez-Machado, J.R. Pérez-Correa, W. Franco

“…These findings highlight the practical utility of MOO-MCDM for designing efficient multiobjective fermentation processes in functional food development.…”
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Artificial intelligence-driven fuzzy logic approach for optimal well selection in gas lift design: A brown field case study by Nnaemeka Princewill Ohia, Chadi Paul, Emmanuel Asolo, Taiwo Adetomiwa Adewa, Chidimma Favour Chukwu, Paschal Ateb Ubi, Daniel Hogan Itam, Daniel Ugochukwu Nnaji

“…However, selecting suitable wells for gas lift is complex due to the inherent uncertainty and variability in petroleum production data. Traditional decision-making approaches often struggle with this uncertainty, leading to suboptimal choices that can reduce efficiency and increase operational costs. …”
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