p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system. by Virginia Andreotti, Yari Ciribilli, Paola Monti, Alessandra Bisio, Mattia Lion, Jennifer Jordan, Gilberto Fronza, Paola Menichini, Michael A Resnick, Alberto Inga

“…<h4>Methodology/principal findings</h4>Given the many factors that might influence p53 function, including expression levels, mutations, cofactor proteins and small molecules, we expanded our previously described yeast-based system to provide the opportunity for efficient investigation of their individual and combined impacts in a miniaturized format. …”
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An improved robust variance inflation factor: Reducing the negative effects of good leverage points by Osman Ufuk Ekiz

“…It is defined as the function of the coefficient of determination between the explanatory variables, and it is based on the maximum likelihood estimator of the regression coefficients. …”
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The Design and Analysis of a Lightweight Robotic Arm Based on a Load-Adaptive Hoisting Mechanism by Ruchao Wang, Zhiguo Lu, Yiru Wang, Zhongqing Li

“…The proposed design integrates a spring-loaded rope and a variable radius reel into the gripper, enabling efficient load adaptability with minimal structural complexity. …”
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Torsional Vibration Suppression During Mode Transition Process in a Parallel Hybrid Electric Vehicle Based on Multiple Model Predictive Control by Cheng Huang, Changqing Du, Longjian Li, Xiangyu Gongye, Yifan Zhao

“…At the same time, the influence of the cost function, the weight coefficient, and the predictive time domain on the torsional vibration suppression effect during the mode transition process are explored in the mMPC strategy design, and the solution time is controlled within 10ms, which meet the real-time requirements. …”
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A Lie Symmetry Classification of a Nonlinear Fin Equation in Cylindrical Coordinates by Saeed M. Ali, Ashfaque H. Bokhari, F. D. Zaman

“…The nonlinear fin equation in cylindrical coordinates is considered. Assuming a radial variable heat transfer coefficient and temperature dependent thermal conductivity, a complete classification of these two functions is obtained via Lie symmetry analysis. …”
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True amplitude migration in constant gradient velocity media by Castillo López Luis Antonio

“…&lt;p class="MsoNormal" style="line-height: normal; margin: 0cm 0cm 0pt; mso-layout-grid-align: none;"&gt;&lt;span style="font-family: ";Arial";,";sans-serif";; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US"&gt;The kirchhoff conventional algorithm using ray tracing is based on a constant velocity function. This solution, where is incorporated ray path information into conventional algorithm, can be extended to a variable velocity medium. …”
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Distributionally Robust Variational Quantum Algorithms With Shifted Noise by Zichang He, Bo Peng, Yuri Alexeev, Zheng Zhang

“…We model the noise level as a random variable with an unknown probability density function (PDF), and we assume that the PDF may shift within an uncertainty set. …”
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Predicting heat transfer Performance in transient flow of CNT nanomaterials with thermal radiation past a heated spinning sphere using an artificial neural network: A machine learn... by S.R. Mishra, P.K. Pattnaik, Rupa Baithalu, P.K. Ratha, Subhajit Panda

“…An efficient heat transfer phenomenon using nanofluid have greater challenges in various industries, engineering application the recent trend. …”
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Parametric Survival Models of Hemodialysis Patients in Relation with Patient-Related Factors by Reem Yousif MEKKI, Mohamed Hassan MUDAWI, Manahil Saidahmed MUSTAFA, Altaiyb Omer Ahmed MOHMMED, Ahmed Bakheet Abd ALLA, Abdel Rahman AHMED

“…Based on the Cox-Snell Residuals and AIC, BIC, and Gompertz (PH) model is an efficient model than other when the values of (AIC=662.21), (BIC=703.83) and (R2=0.211) where maintained Study assessed that the variables dealing with univariate models were signifi cant but had a signifi cant effect on hemodialysis survival. …”
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Trajectory Planning Method in Time-Variant Wind Considering Heterogeneity of Segment Flight Time Distribution by Man Xu, Jian Wang, Qiuqi Wu

“…This study aims to optimize a reliable and efficient trajectory by minimizing the Mean-Excess Flight Time (MEFT). …”
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A Simple and Effective KAN-Based Architecture for Accurate Battery RUL Prediction by Guangzai Ye, Li Feng, Jianlan Guo, Yuqiang Chen, Shufei Li

“…Our approach integrates a VMD-based denoising mechanism, compressed into a more compact KAN model via knowledge distillation, to mitigate noise efficiently. It also incorporates a channel-independent KANs structure with a regularized weighted loss function to handle variable-specific degradation patterns. …”
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Developing data driven framework to model earthquake induced liquefaction potential of granular terrain by machine learning classification models by Kennedy C. Onyelowe, Viroon Kamchoom, Tammineni Gnananandarao, Krishna P. Arunachalam

“…The high precision and Phi Correlation Coefficient further affirm the reliability and accuracy of the model’s predictions. …”
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Comparative evaluation of machine learning models for enhancing diagnostic accuracy of otitis media with effusion in children with adenoid hypertrophy by Xiaote Zhang, Qiaoyi Xie, Ganggang Wu

“…Confusion matrix analysis further confirmed RF as the optimal model, achieving 0.875 accuracy and robust inter-rater agreement (Cohen's kappa coefficient = 0.696) in the testing cohort. SHAP analysis identified the adenoid-to-nasopharyngeal ratio as the predominant diagnostic indicator, followed by tympanometric type and history of recurrent respiratory infections.ConclusionAn RF-based diagnostic model effectively identifies OME in AH children by integrating anatomical, functional, and inflammatory parameters, providing a clinically applicable tool for enhanced diagnostic accuracy and evidence-based management decisions.…”
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Optimization Design of CO2 Air Cooler by Liu Bin, Su Yun, Dong Xiaoyong, Wang Congfei, Cai Jinghui

“…Volume and the heat transfer coefficient of the heat exchanger are taken as an object function respectively, and fin-pitch, tube distance, tube rows, row numbers, diameter of heat pipe and the lengths of single pipe are selected as decision variables. …”
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Evaluating the Potential Use of Wearable Fitness Devices as a Measure of Outcomes in Orthopaedics by Jordan Henderson BS, Santiago Logan-Baca BS, Sara Kisiel BS, Fadi Muheidat PhD, David Jaffe MD

“…Surveys utilized were the Foot and Ankle Ability Measure Computerized Adaptive Testing (FAAM CAT), PROMIS physical function, mobility and pain interference scores, and Visual Analog Scale (VAS). …”
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Establishing a novel model to assess exercise capacity in chronic heart failure based on stress echocardiography by Huan Cen, Sinan Chen, Shen Feng, Xiankun Chen, Huiying Zhu, Wei Jiang, Han Zhang, Hongmei Liu, Bo Liu, Weihui Lu, Pengtao Sun

“…The analytical features of all patients in the four phases (rest, warm‐up, peak and recovery phases) of ESE included the following parameters: left ventricular (LV) systolic function, LV systolic function reserve, LV diastolic function, LV diastolic function reserve and right ventricular function. …”
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Bearing Fault Diagnosis under Transient Conditions: Using Variational Mode Decomposition and the Symmetrized Dot Pattern-Based Convolutional Neural Network Model by Jide Jia, Jianmin Mei, Chuang Sun, Fengjuan Yang

“…To eliminate the noise components, VMD was used to decompose the vibration signal into different frequency bands to obtain the intrinsic mode functions (IMFs), which were further represented by SDP images, and feature images were extracted according to the noncorrelation coefficient. …”
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Proposing Optimized Random Forest Models for Predicting Compressive Strength of Geopolymer Composites by Feng Bin, Shahab Hosseini, Jie Chen, Pijush Samui, Hadi Fattahi, Danial Jahed Armaghani

“…We present a comparative analysis of two hybrid models, Harris Hawks Optimization with Random Forest (HHO-RF) and Sine Cosine Algorithm with Random Forest (SCA-RF), against traditional regression methods and classical models like the Extreme Learning Machine (ELM), General Regression Neural Network (GRNN), and Radial Basis Function (RBF). Using a comprehensive dataset derived from various scientific publications, we focus on key input variables including the fine aggregate, GGBS, fly ash, sodium hydroxide (NaOH) molarity, and others. …”
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Cognitive performance classification of older patients using machine learning and electronic medical records by Monika Richter-Laskowska, Ewelina Sobotnicka, Adam Bednorz

“…Various ML techniques are evaluated to classify cognitive performance levels based on input features such as sociodemographic variables, lab results, comorbidities, Body Mass Index (BMI), and functional scales. …”
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Theoretical and technical concept of cemented backfill material for flexible enhanced thermal energy storage in coal underground space by Chao LYU, Wenyu LYU, Qiang SUN, Panshi XIE, Ding LANG, Songtao JI, Jianjun HU

“…The research status of backfill mining is analyzed based on the current coal mining technology and the scientific concept of "cemented backfill material for flexible enhanced thermal energy storage (CBM–FETES)" is proposed by integrating the idea of functional filling. The core of CBM–FETES is to ensure the four essential conditions: the suitability of geological conditions, the feasibility of thermal storage and extraction technologies, high efficiency in heat and mass transfer, and the safety and stability of the operational cycle. …”
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