Drug Release Analysis and Optimization for Drug-Eluting Stents by Hongxia Li, Yihao Zhang, Bao Zhu, Jinying Wu, Xicheng Wang

“…The diffusion coefficients and the coating thickness are selected as design variables. …”
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Unraveling novel variants in the NF1 gene and investigating potential therapeutic strategies by Jianmei Huang, Ke Yang, Yaoping Wang, Xinrui Ma, Wenke Yang, Xiaodong Huo, Jie Bai, Hongjie Zhu, Jinming Wang, Yibing Lv, Shixiu Liao

“…A retrospective analysis of 49 clinical trials over the past 20 years revealed that NF1 therapies predominantly target neurofibromin’s GTPase function. Gene therapies aiming to restore neurofibromin by transducing the truncated NF1-GRD gene have been developed but faced pre-clinical challenges, including cloning capacity, transduction efficiency, and immunogenicity caused by gene delivery. …”
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Translation and validation of Gujarati version of Indian HAQ in RA patients by Jaspreet Kaur Kang, Neeta J Vyas

“…Results: Internal consistency of each item was evaluated by Cronbach's alpha and the Construct validity was evaluated by determining Spearman's correlation between the Gujarati Indian HAQ score and disease activity variables. Reliability testing showed an intraclass coefficient for HAQ of 0. 848. …”
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Analysis of fuzzy TOPSIS Method in Determining Priority of Small Dams Construction by Desyta Ulfiana, Suharyanto Suharyanto

“…The first step was determining membership function and weighting each criteria. Then, TOPSIS method was applied to ranked eight alternatives. …”
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Impact of coffee exports on economic growth in Ethiopia; An empirical investigation by Netsanet Gizaw, Jemal Abafita, Tesfaye Melaku Merra

“…The study employed an extended generalized Cobb–Douglas production function model using data from the National Bank of Ethiopia and World Bank data base from 1980 to 2017. …”
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Time-Jerk Optimal Robotic Trajectory Planning Under Jerk and Continuity Constraints via Convex Optimization by Chen Qian, Jianjun Yao, Yikun Zhang

“…Additionally, the objective function is improved to optimize both time and joint jerk simultaneously. …”
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Hydrodynamic and sensitivity analysis of a polymeric calendering process for non-Newtonian fluids with temperature-dependent viscosity by Ali Fateh, Zahid Muhammad, Farmer M., Al Taisan Nada, Faqihi Abdullah A., Souayeh Basma, Raju S. Suresh Kumar, Alam Mir Waqas

“…Additionally, using the response surface method, Nusselt number (Nu)(\text{Nu}), sheet thickness HH0\left(\phantom{\rule[-0.75em]{}{0ex}},\frac{H}{{H}_{0}}\right), and shear stress (Sxy)({S}_{xy}), simulations were carried out to investigate the influence of variable viscoelastic parameters on the response functions (Nu\text{Nu}, HH0\frac{H}{{H}_{0}}, and Sxy{S}_{xy}). …”
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Optimization by RSM of reinforced concrete domes with meridian ribs, under static loading. by Logzit N., Raouache E., Bentoumi M., Bentoumi A., Khababa I.

“…Ultimately, a cost-oriented objective function is derived, incorporating a load-bearing capacity coefficient. …”
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Estimation of Above-Ground Biomass for <italic>Dendrocalamus Giganteus</italic> Utilizing Spaceborne LiDAR GEDI Data by Huanfen Yang, Zhen Qin, Qingtai Shu, Li Xu, Jinge Yu, Shaolong Luo, Zaikun Wu, Cuifen Xia, Zhengdao Yang

“…The outcomes reveal that 1) the results showed that the power function emerged as the most efficacious model, with coefficient of determination (<italic>R</italic>²) &#x003D; 0.87 and root mean square error (RMSE) &#x003D; 0.00051 Mg, in estimating the AGB of <italic>Dendrocalamus giganteus</italic>. 2) Based on the feature importance ranking of Random Forest, five variables were selected from the 40 extracted from GEDI, achieving RMSE &#x003D; 8.21 Mg&#x002F;ha and mean absolute error (MAE) &#x003D; 6.12 Mg&#x002F;ha. …”
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A New Optimization Approach for Maximizing the Photovoltaic Panel Power Based on Genetic Algorithm and Lagrange Multiplier Algorithm by Mahdi M. M. El-Arini, Ahmed M. Othman, Ahmed Fathy

“…The technique which is based on objective function represents the output power of the PV panel and constraints, equality and inequality. …”
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A Three-Block Inexact Heterogeneous Alternating Direction Method of Multipliers for Elliptic PDE-Constrained Optimization Problems with a Control Gradient Penalty Term by Xiaotong Chen, Tongtong Wang, Xiaoliang Song

“…In some practical applications, it is necessary to smooth the control variables and suppress their large fluctuations, especially at the boundary. …”
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THE STRUCTURE OF HAPPINESS REPRESENTATION FOR RUSSIAN AND AMERICAN REPRESENTATIVES by S. Yu. Zhdanova, A. V. Pecherkina, A. A. Strokanov

“…Statistical analysis of the data was based on the use of the coefficient of φ-angular Fisher transform, correlation coefficient φ, and cluster analysis.Results and scientific novelty. …”
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Optimization of fermentation conditions for enhanced acetylcholine and biomass production of Lactiplantibacillus plantarum AM2 using the Taguchi approach by Walid A. Lotfy, Amira M. Ali, Heba M. Abdou, Khaled M. Ghanem

“…Abstract This study aimed to optimize the fermentation conditions and medium composition for maximum acetylcholine (ACh) and biomass production by Lactiplantibacillus plantarum AM2 using the Taguchi array design, which enables efficient identification of influential variables through minimal experimental runs. …”
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Binary composite crossover genetic algorithm for locating critical slip surface by Wei Qin, Jiancheng Zhao

“…A reasonable combination of parameters for the binary composite crossover (BCC) operator in the RGA-BCC is determined through six benchmark function experiments. On this basis, the stability of five soil slopes from the literature was analysed using the RGA-BCC in combination with the Morgenstern and Price method, and the results obtained were compared with those in the published literature to demonstrate that the RGA-BCC is able to efficiently determine the CSSs of slopes and their minimum factors of safety. …”
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Optimization of Aerodynamic Design of a Winged UAV Through Genetic Algorithms and Large Eddy Simulation by Mohammad Javad Ebrahimi, Mahmoud Pasandidehfard, Ali Esmaeili, Mohammad Hossein Moghimi Esfandabadi

“…Optimization was conducted for six variables in a single stage, with 25 tests performed. …”
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Optimal tuning of multi-PID controller using improved CMOCSO algorithm by Ying Hu, Xiongyan Liu, Hao Chen

“…In this model, the parameters are designated as decision variables, the performance index serves as the objective function, and the stability constraints of the system are incorporated. …”
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Performance Investigation of Coated Carbide Tools in Milling Procedures by Paschalis Charalampous

“…The optimization of the manufacturing conditions in milling processes composes a crucial task for enhancing machining efficiency and extending the tool’s lifespan. This study presents an investigation of the cutting tool’s performance under varying machining parameters via the generation of an experimental dataset that was obtained through laboratory-controlled milling operations. …”
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Decentralized queue control with delay shifting in edge-IoT using reinforcement learning by Viacheslav Kovtun

“…Analytical expressions for key QoS indicators (delay, variability, loss, energy consumption) as functions of the shift parameter are derived, and a multi-factor reward function is constructed. …”
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Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
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Analysis of value-based healthcare (VBHC) framework by incremental cost-effectiveness of surgical and therapeutic interventions: a retrospective study at tertiary private health gr... by Mona Khamis, Zainab Almoosa, Marie Santos, Engineer Diaa Kamal, Suhail Yaghmor, Muhammad Daniyal, Abbas Al Mutair

“…Additionally, ICER values were positively associated with better functional outcomes in MS and stroke patients, with mobility (b = 1.027, p = 0.003) and activity (b = 1.768, p < 0.001). …”
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