Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. by Maila Giannandrea, Fabrizia C Guarnieri, Niels H Gehring, Elena Monzani, Fabio Benfenati, Andreas E Kulozik, Flavia Valtorta

“…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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Influence of heavy oil components and optimal magnetic nanocatalysts on the heavy oil upgrading by microwave-assisted by Parya Torkaman, Ramin Karimzadeh, Arezou Jafari

“…It indicates a slight loss in efficiency due to aggregation or degradation.…”
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Statistical learning-driven parameter tuning in injection molding using modified simplex method by Pongchanun Luangpaiboon, Walailak Atthirawong, Anucha Hirunwat, Pasura Aungkulanon

“…The Taguchi design of experiments and desirability function analysis were employed to establish a baseline. …”
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Transient decline and early recovery of noninvasive myocardial work after kidney transplantation: a prospective study by Yulin Huang, Lin Jin, Xinyan Qiu, Canying Yang, Luyi Ping, Zhengyao Jiang, Hua Zou, Zhihong Zhang, Jiwei Wang

“…NIMW parameters include global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE).Results 1) Renal function indicators, including blood urea nitrogen, serum creatinine, and estimated glomerular filtration rate improved significantly at 10 days post-KT. …”
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Eficiência técnica na suinocultura: efeitos dos gastos com meio ambiente e da renúncia fiscal Technical efficiency in swine breeding: effect of the expenses with the environment an... by Benedito D. Pereira, João C. de S. Maia, Rosalina Camilot

“…After estimating the technical efficiency indices with data of ten properties situated in Mato Grosso from production functions, whose dependent variable is represented by the production of swine and the independent ones are the consumption of water, electricity and the amount of workers directly tied with the productive process. …”
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Sensitivity Analysis of Numerical Coherency Model for Rock Sites by Dongyeon Lee, Yonghee Lee, Hak-Sung Kim, Jeong-Seon Park, Duhee Park

“…Because of difficulties in developing an empirical coherency function from a site-specific dense array, it is seldom used in practice. …”
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Methodology for assessing the spherical plain bearings durability by V. K. Harina, O. A. Ratenko, G. B. Vardanyan

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Optimizing a Bayesian Method for Estimating the Hurst Exponent in Behavioral Sciences by Madhur Mangalam, Taylor J. Wilson, Joel H. Sommerfeld, Aaron D. Likens

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Measurement of Salivary Cortisol for Revealing Age-Specific Dependence of Cortisol Levels on Time, Feeding, and Oxygen Metabolism in Newborn Infants by Tomoko Suzuki, Sachiko Iwata, Chinami Hanai, Satoko Fukaya, Yuka Watanabe, Shigeharu Nakane, Hisayoshi Okamura, Shinji Saitoh, Osuke Iwata

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Pectin extraction from cocoa husk of different genotypes and stages of ripeness by Enrique Arévalo-Gardini, Cesar Oswaldo Arévalo-Hernández, Virupax Baligar, Dapeng Zhang

“…Results showed that genotype and ripeness significantly affect extraction efficiency and pectin functionality. The highest pectin yield was 77.7% for IMC-67 (ripe) and 72.6% for CCN51 (semi-ripe) at optimal conditions (pH 1.5–1.6, 80 °C, 75 minutes). …”
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Evaluating the effects of urban development on the ecological carrying capacity of Isfahan city based on the system dynamics approach by Zahra Dehghan Manshadi, Parastoo Parivar

“…In order to validate the model, the historical trend and simulation of two variables of urban population and the number of industries have been compared using the coefficient of determination.Results and discussion: The pressure factors on the urban carrying capacity were detected and analyzed by assessing key variables in the system, such as water sustainability (WSI) and air quality, as well as changes in the landscape structure of Isfahan using landscape metrics. …”
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Optimal ANOVA-Based Emulators of Models With(out) Derivatives by Matieyendou Lamboni

“…Our emulators are also competitive in dealing with different distributions of the input variables and selecting inputs and interactions. Simulations show the efficiency of our approach.…”
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Direct methanol fuel cells parameter identification with enhanced algorithmic technique by Manish Kumar Singla, Muhammed Ali S.A, Ramesh Kumar, Hamed Zeinoddini-Meymand, Farhad Shahnia

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Study on Operation Control Strategy for Campus Public Building Heating Systems in Severe Cold Areas by Chuntian Lu, Shourui Xue, Yuetong Zhang, Songqing Wang

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Random Finite Element Analysis and Random Factor response Mechanism for Geocell-reinforced Soil Retaining Walls by ZHANG Bingbing, SONG Fei

“…For this reason, a finite element analysis method based on random field theory is proposed in this paper, which can more realistically reflect the non-homogeneous characteristics of the reinforced soil retaining wall system by introducing a spatial random distribution model of the soil parameters and the mechanical properties of the geocells, so as to more accurately assess the influence of the spatial variability of the material parameters on the deformation behavior and stability of the retaining wall.MethodsFirstly, in parameter random field modeling, an innovative combination of Latin Hypercube Sampling (LHS) and exponential autocorrelation function is used to construct parameter random fields. …”
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How Can We Manage Repairing a Broken Finite Vibrating String? Solutions to the Problem I by Vladimir L. Borsch

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Three-dimensional design, simulation and optimization of a centrifugal compressor impeller with double-splitter blades by Mohammadjavad Tasharrofi, Mojtaba Heidarian Shahri, Ali Madadi

“…Since the optimization process only using genetic algorithms is very time-consuming and has high computational costs, artificial neural networks were used to reduce costs. The objective function in this optimization process was to increase efficiency while maintaining the flow rate and pressure ratio at the design point. …”
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Multifractal analysis of Bitcoin price dynamics by Cristian Bucur, Bogdan-George Tudorică, Adela Bâra, Simona-Vasilica Oprea

“… This research employs Multifractal Detrended Fluctuation Analysis (MFDFA) to investigate multifractal properties in financial variables, including Bitcoin prices and economic indicators. …”
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Vehicle detection method based on multi-layer selective feature for UAV aerial images by Yinbao Ma, Yuyu Meng, Jiuyuan Huo

“…However, this task remains challenging due to variable high-altitude viewpoints, complex environmental interference, and limitations in algorithmic efficiency. …”
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Optimization of MXene-based aqueous ionic liquids for solar systems using conventional and AI-based techniques by Mohamed Bechir Ben Hamida, Ali B. M. Ali, Narinderjit Singh Sawaran Singh, Loghman Mostafa

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