Potential Protective Effect of Orlistat: A Formulation of Nanocrystals Targeting Inflammation, Oxidative Stress, and Apoptosis in an Experimental Model of Doxorubicin-Induced Cardi... by Maha Alsunbul, Thanaa A. El-Masry, Enas I. El Zahaby, Mohamed M. S. Gaballa, Maysa M. F. El-Nagar

“…The study results indicated that DOX caused significant cardiotoxicity, as revealed by a remarkable rise in cardiac function biomarkers like LDH and CK-MB, which involve enzyme activities. …”
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PileBetaGR: An R-based integrative tool for predicting the geometric reliability index of piles using load-displacement curves by Xing Zheng Wu

“…The application compiles a series of functions for analyzing load-displacement data: (i) a power law regression is used to fit each load-displacement curve, yielding a set of regression parameters for the site; (ii) a normal copula model is established to fit the joint distribution of these regression variables, allowing a geometric reliability index to be computed; (iii) the critical environmental contour is determined based on the joint probability density function and the limit state function. …”
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Identification of Factors Affecting Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…Risk management is now an important part of project management and has a specific function for improving the efficiency of implementing the project, saving prices, and improving the profitability of projects. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Actigraphy was used to evaluate sleep and circadian rhythm, while HRV was monitored for 24 hours to assess autonomic nerve function. Nonparametric indicators were calculated to quantify the active-rest patterns, including interdaily stability, intradaily variability, the most active 10 consecutive hours (M10), the least active 5 consecutive hours (L5), the relative amplitude, and the actigraphic dichotomy index. …”
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Fiscal Sustainability in Iran A Markov-Switching Fiscal Regime Change and Time-Varying Parameter Models Approach by Hossein Aghilifar, Khosrow Piraei, Hashem Zare, Mehrzad Ebrahimi

“…Then the Markov-switching fiscal regime change model and the time-varying parameter fiscal reaction function are estimated. Among the constant parameter linear and non-linear models, only the linear model including control variables has a significant debt-to-GDP ratio coefficient, which its sign is negative. …”
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Optimization Study of PVT Coupled Water Loop Heat Pump Energy Supply System by Lv Tiangang, Liu Bing, Wu Jun, Zhu Li, Hou Jingxuan

“…By employing the Hooke-Jeeves algorithm, the system's design and operation parameters were optimized with annual cost and system COP as objective functions. Design variables included PVT inclination, azimuth, area, heat pump capacity, and tank volume, while operational variables were PVT backplate temperature and tank temperature. …”
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Optimization of K-Shaped Metal Sealing Ring for Subsea Tubing Hanger Based on Response Surface Method by Huan Xie, Hongxia Zhang, Yiwei Fan, Liyuan Liu, Wei Zeng

“…To address the issue of low optimization efficiency due to the need for repeated finite element calculations during the optimization process, quadratic response surface models are established for the sealing performance indicators of the K-shaped seal ring, which were then used as the optimization objective functions to enhance the optimization efficiency. …”
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Extreme combination of wind effects and analysis of wind load characteristics for low-rise buildings by Haiwei Guan, Yuji Tian, Yuliang Qi, Weihu Chen

“…Based on transcendental probability theory, the probability density functions of two non-Gaussian scalar sums of wind effects are derived from the relationship between the probability density of the sum of random variables and the joint probability density function of sub-random variables by Hermite polynomial transformation. …”
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MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…IntroductionThe role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. …”
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Application of Optimization Algorithms in Voter Service Module Allocation by Edgar Jardón, Marcelo Romero, José-Raymundo Marcial-Romero

“…These findings align with principles of spatial justice and highlight the practical efficiency of heuristic-based solutions in administrative resource allocation. …”
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REVIVAL OF TOURISM DEMAND IN THE POST COVID-19 PANDEMIC PERIOD - A STATISTICAL OVERVIEW IN ROMANIA by Agatha POPESCU, Cristina TINDECHE, Alina MARCUTA, Liviu MARCUTA, Adelaida HONTUS, Mirela STANCIU, Daniela-Mirela PLESOIANU

“…Dynamics of the tourist arrivals and overnight stays involved to establish the trend using polynomial regression functions and determination coefficient. The results showed that the recovery of the tourist flow from its lowest level registered in 2020, the worst year of tourism during the pandemic, needed three years to attain a higher performance than in 2019, a year which was considered the peak in Romania's tourism. …”
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Manufacturing of Rotational Toroidal Shells in Coin Minting by Luís M. Alves, Paulo Alexandrino, Sónia Pereira

“…Through finite element modeling and experimentation, key process variables were identified, ensuring sound hollow toroidal shells with efficient rotation.…”
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Clinical diagnostic and prognostic value of homocysteine combined with hemoglobin [f (Hcy-Hb)] in cardio-renal syndrome caused by primary acute myocardial infarction by Min-Juan Zeng, Yan-Quan Liu, Ping Pang, Xiao-Jun Chen, He Huang, Rui-Na Huang, Shi-Sen Li, He-Hui Zhang, Yue Yin, Chang-Sen Wang, Jin-Da Lin, Lin Lin, Shao-Peng Chen, Li Xu, Liang-Qing Zhang

“…Conclusion The newly constructed function [f (Hcy-Hb)], integrating Hcy and Hb levels, exhibits robust diagnostic and prognostic value in CRS. …”
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Modeling of Ozone Interactions with Various Air Pollutants and Meteorological Factors Using Jaya and Teaching-Learning Based Optimization (TLBO) Algorithms by Nurcan Öztürk

“…In conclusion, it is shown that Jaya and TLBO algorithms can be used in the optimization of the regression function coefficients in modelling some air pollutants interactions and the best-fit equation for each parameter is obtained from the quadratic function.…”
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Effects of Indoor Air Quality on Human Physiological Impact: A Review by Tong Nie, Guofu Zhang, Yinan Sun, Wenhao Wang, Tianai Wang, Haoyan Duan

“…Through an analysis of cardiovascular biomarkers (heart rate variability, blood pressure), respiratory parameters, and neurological indicators (electroencephalogram patterns), we identify the mechanisms linking air quality degradation to impaired physiological functioning. …”
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ANALYSIS OF PATH NONPARAMETRIC TRUNCATED SPLINE MAXIMUM CUBIC ORDER IN BANKING CREDIT OF RISK BEHAVIOR MODEL by Devi Veda Amanda, Atiek Iriany, Adji Achmad Rinaldo Fernandes, Solimun Solimun

“…Based on the results of the analysis, it is known that the best-truncated spline nonparametric path model is the quadratic order of 2 knots with a coefficient of determination of 85.50%; the significance of the best-truncated spline nonparametric path estimator shows that all exogenous variables have a significant effect on endogenous variables.…”
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Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity by Chunbo Zhang, Kunyao Yu, Zhe Jin, Yingcong Bao, Cheng Zhang, Jiping Liao, Guangfa Wang

“…A logistic regression model using the RR and blowing sounds as key predictors achieved accuracies of 0.77–0.89 in determining the GOLD grade, with a Cohen's kappa coefficient of 0.6757. Conclusions Audio data were more strongly correlated with lung function in COPD patients than were physiological parameters. …”
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Fractional Dynamics of Laser-Induced Heat Transfer in Metallic Thin Films: Analytical Approach by M. A. I. Essawy, Reham A. Rezk, Ayman M. Mostafa

“…Dynamic profiles demonstrate the responsiveness of heat transfer to thermal and optical variables. The innovation resides in the meticulous analytical formulation utilizing a realistic laser source, the clear significance of the absorption parameter that enhances the temperature amplitude, the incorporation of the Mittag–Leffler function, and a comprehensive investigation of fractional photothermal effects in metallic nano-systems. …”
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Rethinking energy security in the condition of a rise in public–private partnership in energy: Fresh insights from new estimation by Le Thanh Ha

“…High energy efficiency increases the energy system's resilience by ensuring that systems with restricted funds continue functioning in the event of energy restrictions or global uncertainty.…”
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Statistical Modeling and Kinetic Studies on the Adsorption of Reactive Red 2 by a Low-Cost Adsorbent: Grape Waste-Based Activated Carbon Using Sulfuric Acid Activator-Assisted Ther... by Seyyed Alireza Mousavi, Davood Shahbazi, Arezoo Mahmoudi, Parviz Mohammadi, Tooraj Massahi

“…The efficiency of activated carbon produced from grape waste as a low-cost, nontoxic, and available adsorbent to remove Reactive Red 2 from aqueous solution has been investigated. …”
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