Uncovering glycolysis-driven molecular subtypes in diabetic nephropathy: a WGCNA and machine learning approach for diagnostic precision by Chenglong Fan, Guanglin Yang, Cheng Li, Jiwen Cheng, Shaohua Chen, Hua Mi

“…The hub genes associated with DN and glycolysis-related clusters were identified via weighted gene co-expression network analysis (WGCNA) and machine learning algorithms. …”
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A Step Forward in Long COVID Research: Validating the Post-COVID Cognitive Impairment Scale by Somayeh Pour Mohammadi, Razieh Etesamipour, Francisco Mercado Romero, Irene Peláez

“…Long COVID, or post-acute sequelae of SARS-CoV-2 infection, includes a variety of enduring symptoms that endure beyond the acute phase of the illness, impacting multiple facets of patients’ psychological and physical health. …”
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Development of a framework for safety and resilience in overhead power cables: Use of a fuzzy inference system for risk and reliability analysis by A.M. Sakura R.H. Attanayake, R.M. Chandima Ratnayake, T. Markeset

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The gene regulatory mechanisms shaping the heterogeneity of venom production in the Cape coral snake by Pedro G. Nachtigall, Brett R. Hamilton, Taline D. Kazandjian, Paolo Stincone, Daniel Petras, Nicholas R. Casewell, Eivind A. B. Undheim

“…Within these venom systems, the molecular, cellular, and morphological components interact and co-evolve to generate distinct, venom phenotypes that are increasingly recognized as models for studying adaptive evolution. …”
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Predictors of length of hospital stay in patients with acute COVID-19 by E. S. Pan’ko, S. V. Zhavoronok, A. M. Solovchuk, S. S. Pan’ko, S. V. Pan’ko

“…Log-regression models were used to assess the suitability of some functional spirometric variables and/or SpO2/FiO2 surrogate oxygenation index to predict the duration of inpatient treatment from the day of the examination (≤ 7 vs. …”
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Marine environmental monitoring programmes in South Africa: a review by L. Hutchings, M. Roberts, H. Verheye

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A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected]. by Sally H Cross, Danilo G Macalinao, Lisa McKie, Lorraine Rose, Alison L Kearney, Joe Rainger, Caroline Thaung, Margaret Keighren, Shalini Jadeja, Katrine West, Stephen C Kneeland, Richard S Smith, Gareth R Howell, Fiona Young, Morag Robertson, Rob van T' Hof, Simon W M John, Ian J Jackson

“…We show that the null phenotype is rescued more effectively by an Lmx1b transgene than is Icst. Co-immunoprecipitation experiments show that both wild-type and Icst LMX1B are found in complexes with LIM domain binding protein 1 (LDB1), resulting in lower levels of functional LMX1B in Icst heterozygotes than null heterozygotes. …”
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High performance of a low input, mixed western Australian farming system: public policy implications from the case of Tolga farm by Bradley Plunkett, Daniel Roberts, Sudarshan Kharel, Kevin Foster, Tim Overheu, Brendon Savage

“…The business has steadily grown over the past 30 years. Emissions (T/CO2e/ha) are estimated to be low compared to industry benchmarks and evidence exists that the farm’s total organic carbon pool is either reflective of or is as much as 40% higher than the surrounding area.…”
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Genome-wide identification and salt stress-responsive expression profiling of Aux/IAA gene family in Asparagus officinalis by Shuangshuang Wen, Jiali Ying, Youju Ye, Yunfei Cai, Lebin Li, Renjuan Qian

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FAT1-weighted MRI-guided focused ultrasound thalamotomy for essential tremor by Indran Davagnanam, San San Xu, Thomas Foltynie, Ludvic Zrinzo, Prasad Korlipara, Patricia Limousin, Tabish A Saifee, Jonathan Hyam, Harith Akram, Marie T Krüger, Valentina Lind

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Enterotype-stratified gut microbial signatures in MASLD and cirrhosis based on integrated microbiome data by Heng Yuan, Heng Yuan, Junyu Zhou, Junyu Zhou, Xuangao Wu, Shiwei Wang, Sunmin Park, Sunmin Park

“…Enterotype classification was performed using principal component analysis, with advanced bioinformatics tools, including Linear Discriminant Analysis Effect Size (LEfSe), eXtreme Gradient Boosting (XGBoost), and Deep Cross-Fusion Networks for Genome-Scale Identification of Pathogens (DCiPatho), to identify differentially abundant microbes and potential pathogens. Microbial co-occurrence networks and functional predictions via PICRUSt2 revealed distinct patterns across enterotypes.Results and discussionThe Prevotella-dominated(ET-P) group exhibited a 33% higher cirrhosis rate than the Bacteroides-dominated(ET-B) group. …”
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Assessment of infiltration and erosion rates in Mediterranean reservoirs’ catchments through rainfall simulation by Jorge Mongil-Manso, Carmen Patino-Alonso, José Nespereira-Jato, José-Luis Molina, Fernando Espejo, Teresa Diez-Castro, Santiago Zazo, Fernando Silla

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The Atmospheric Sounder Spectrometer by Infrared Spectral Technology (ASSIST): instrument design and signal processing by V. Michaud-Belleau, M. Gaudreau, J. Lacoursière, É. Boisvert, L. Ravelomanantsoa, D. D. Turner, L. Rochette

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Comparative genomics reveals key adaptive mechanisms in pathogen host-niche specialization by Menglu Zhang, Longxi Han, Caizhi Liao, Weiheng Su, Weiheng Su, Chunlai Jiang, Chunlai Jiang

“…Bioinformatics databases and machine learning approaches were used to identify genomic differences in functional categories, virulence factors, and antibiotic resistance genes across different ecological niches.ResultsSignificant variability in bacterial adaptive strategies was observed. …”
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Combined Surfactant and Enzyme-Assisted Extraction of Pectin from Hawthorn (Crataegus monogyna Jacq.) Fruits by Anastasia E. Novikova, Liubov N. Skrypnik

“…The hawthorn pectin can be used to develop new functional products.…”
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3D IntelliGenes: AI/ML application using multi-omics data for biomarker discovery and disease prediction with multi-dimensional visualization by Rishabh Narayanan, Elizabeth Peker, William DeGroat, Dinesh Mendhe, Saman Zeeshan, Zeeshan Ahmed

“…Results The overall functionality of 3D IntelliGenes is divided into two modules, data clustering and feature plotting. …”
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Life Cycle Assessment of Key Mediterranean Agricultural Products at the Farm Level Using GHG Measurements by Georgios Bartzas, Maria Doula, Konstantinos Komnitsas

“…The uncertainty analysis indicates that among the LCI-based scenarios evaluated, the IS scenario exhibits the lowest variability, with coefficient of variation (CV) values ranging from 0.5% to 7.3%. …”
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What are the reasons for patients not adhering to their anti-TB treatment in a South African district hospital? by Somasundran Govender, Bob Mash

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Management factors affecting the environmental impact of cereal-based dairy farms by Marco Berton, Enrico Sturaro, Stefano Schiavon, Alessio Cecchinato, Luigi Gallo

“…Impact values were analysed with a linear model to test separately the effects of MAN_F, DIET_F and ANI_F variables. One kg FPCM was associated with an average impact of 1.10 kg CO2-eq (GWP), 17.1 g SO2-eq (AP), 6.0 g PO4-eq (EP), and 1.3 m2/y (LO). …”
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Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

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