A toolkit for facilitating markerless integration of expression cassettes in Komagataella phaffii via CRISPR/Cas9 by Laura García-Calvo, Charlotte Kummen, Solvor Rustad, Sissel Beate Rønning, Annette Fagerlund

“…The 04576 locus showed the highest integration efficiency, while ROX1 had the highest transformation efficiency. …”
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Optimizing switching sequences in AC-AC converters for enhanced safety and performance in conveyor systems by Velmurugan Dhandapani, Gopinath Balasubramanian

“…Industrial systems require optimized control to maintain efficiency under variable loads. Fault conditions influence power stability and overall system functionality. …”
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Accelerating charge estimation in molecular dynamics simulations using physics-informed neural networks: corrosion applications by Aditya Venkatraman, Mark A. Wilson, David Montes de Oca Zapiain

“…This demonstrates the excellent accuracy, computational efficiency, and validity of the developed model. Lastly, even though developed for corrosion, these protocols are formulated in a phenomenon-agnostic manner, allowing application to various variable-charge interatomic potentials and related fields.…”
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A design-based framework for optimal stratification using super-population models with application on real data set of breast cancer. by Faizan Danish

“…This study investigates the determination of stratification points for two study variables within the framework of simple random sampling, with a focus on estimating the population mean using a closely related auxiliary variable. …”
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Numerical and Experimental Study of a Hydrodynamic Analysis of the Periodical Fluctuation of Bio-Inspired Banded Fins by Chonglei Wang, Qihang Liu, Junhao Yang, Chunyu Guo

“…By using a method of controlling variables, such as wave number, swing angle, and frequency, where only one independent variable is changed at a time while the others remain constant, the impact on thrust coefficient function and the obtained periodic variation laws governing hydrodynamic performance are studied. …”
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An Optimal Hybrid Control Method for Energy-Saving of Chilled Water System in Central Air Conditioning by Yan Zhang, Xiaoli Chu, Yongqiang Liu

“…Here, an optimum control method is proposed with the principle of the minimum, by setting the minimum power consumption as the performance function in fixed time, which realizes variable control of pumps and accurate adjustment of temperature inside room. …”
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Jacobian-Free Newton Krylov Methods for Steady and Transient Neutron Transport Models by ZHANG Yangyi, ZHANG Tiancheng, ZHOU Xiafeng

“…To further improve computational efficiency of comeSn_JFNK, in the JFNK solution, neutron scalar fluxes instead of neutron angular fluxes were chosen as the global solution variables. …”

Transfer Robustness Optimization for Urban Rail Transit Timetables by Liqiao Ning, Peng Zhao, Wenkai Xu, Ke Qiao

“…Next, to improve the computational efficiency, we propose an approximate linearization approach for the EETC function and introduce two types of binary variables and auxiliary substitution variables to convert the nonlinear model to a mixed-integer linear model. …”
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A DQN-Based Algorithm for Operational Optimization of Freight Trains in Long Steep Downhill Sections by HE Zhiyu, LI Yinan, LI Hui, JI Zhijun

“…The study employed the batch collection of training samples utilizing experience replay and a double-network mechanism, along with the preprocessing of neural network state inputs, and the investigation into feasible regions within the action space using a variable ε-greedy strategy. A loss function based on the value function was then constructed, and network parameters were updated iteratively by a batch gradient descent method. …”
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Surface Defect Detection for Small Samples of Particleboard Based on Improved Proximal Policy Optimization by Haifei Xia, Haiyan Zhou, Mingao Zhang, Qingyi Zhang, Chenlong Fan, Yutu Yang, Shuang Xi, Ying Liu

“…The method integrates the variable action space and the composite reward function and achieves the balanced optimization of different types of defect detection performance by adjusting the scaling and translation amplitude of the detection region. …”
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COMPARATIVE ANALYSIS OF THE ACADEMIC PERFORMANCE IN THE AGRICULTURAL UNIVERSITIES FROM ROMANIA AND REPUBLIC OF MOLDOVA USING THE NONPARAMETRIC METHOD OF DATA ENVELOPMENT ANALYSIS by Ilie CERCEL, Gina FÎNTÎNERU, Elena TOMA, Augustin VOLCONOVICI, Alla CHIRSANOVA, Anatol RACUL

“…As a result of analyzing the academic performance rating by option variable returns to scale, it is possible to determine the resources for improving staff activity by evaluating the distance function for each causal factor.…”
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Assessing the Effectiveness of DL-Clustering for Energy Optimization in Wireless Sensor Networks by Shailaja S. Halli, Poornima G Patil

“…Determining the fitness function allows us to estimate the player's stability over these variables. …”
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Optimal Control Problem of Converter Steelmaking Production Process Based on Operation Optimization Method by Jun Zhang

“…The optimal control indicator is determined via current state of converter smelting production process, and the set values of operation variable would control converter production. Relationship between various operating variables, current temperature, and carbon content is constructed through operation analysis of a great deal of actual production data; then, the dynamic optimal control indicator is derived from historical excellent smelting data; finally, the dynamic operation optimization model is built by taking the minimum deviation between the current data—molten steel temperature and carbon content—and optimal data which are determined by the optimal control indicator as objective function. …”
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Estimation of micro-extraction process hippuric acid for toluene exposure monitoring in urine samples by Behnaz Sarani, Mashaallah Rahmani, Ahmad Reza Abbasian

“…Abstract This study employed a quick, efficient, sensitive, and easy-to-use micro-extraction process to monitor biomarker hippuric acid (BIHA) in urine samples as a bioindicator of exposure to toluene with an HPLC-DAD instrument. …”
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Methods to Quantitatively Evaluate the Effect of Shale Gas Fracturing Stimulation Based on Least Squares by DENG Cai, SUN Kexin, WEN Huan, HU Chaolang

“…Advanced optimization algorithms were employed to efficiently address both the fitting and calculation tasks. …”
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Mitigating Load Imbalance and Enhancing Distribution Transformer Performance via Fuzzy Inference System by Althoff Hibban, Azriyenni Azhari Zakri, Dirman Hanafi, Boy Ihsan, Umair Ali

“…To address this issue, this study proposes a fuzzy logic-based approach using a Mamdani-type Fuzzy Inference System (FIS). The input variables, current magnitudes in phases R, S, and T, are represented by trapezoidal membership functions classified into several categories. …”
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Pareto Optimal Solutions for Stochastic Dynamic Programming Problems via Monte Carlo Simulation by R. T. N. Cardoso, R. H. C. Takahashi, F. R. B. Cruz

“…Instead of using the expected values of the objective function, the randomness nature of the decision variables is kept along the process, while Pareto fronts weighted by all quantiles of the objective function are determined. …”
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Trajectory Planning Method in Time-Variant Wind Considering Heterogeneity of Segment Flight Time Distribution by Man Xu, Jian Wang, Qiuqi Wu

“…This study aims to optimize a reliable and efficient trajectory by minimizing the Mean-Excess Flight Time (MEFT). …”
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同轴全铰链双输出脉冲发生机构尺度综合与优化 by 杜力, 邹昌平, 冯俊, 向成宣, 黄茂林

“…In order to enhance the efficiency,stability and simplify the structure of the mechanism,the dimension synthesis of the full hinge coaxial two-output function generator is performed by using group-synthesis scheme and regarding the six-bar mechanism as the parallel mechanism of a set of basic four-bar mechanism and a set of equivalent four-bar mechanism.Firstly,a basic four-bar mechanism synthetic model is established and solved based on two position synthesis and equal instantaneous transmission ratio.Then the dimensional parameters of an equivalent four-bar mechanism（a five-bar loop） is solved by using equivalent principle of a variable link-length four-bar mechanism based on the basic four-bar mechanism.By this scheme,the dimensional synthesis of high order of motion parameter can be solved with good results,and the results show that the pulse data of the full hinge coaxial two-output function generator is only six percent.…”
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The performance of 76 kHz positional acoustic telemetry is challenged by acoustic conditions in the tailrace of a hydroelectric dam by C. Ryan Hill, Antóin M. O’Sullivan, R. Allen Curry, Tommi Linnansaari, Philip M. Harrison

“…Performance improved marginally for the second array (i.e., 200–500 m downstream), but position efficiency was ultimately low (1%), variable across transmitter locations, and negatively correlated with discharge. …”
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