KNOT OPTIMIZATION FOR BI-RESPONSE SPLINE NONPARAMETRIC REGRESSION WITH GENERALIZED CROSS-VALIDATION (GCV) by Andre Fajry Al Barra, Dewi Retno Sari Saputro

“…Nonparametric regression is a statistical method used to model relationships between variables without making strong assumptions about the functional form of the relationship. …”
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The role of personalized precision medicine in enhancing diagnostic accuracy and clinical outcomes by Shamala Devi Sekaran, Rishya Manikam, Gaythri Thergerajan, Haymond Prasad, Munandy Alagar, Chung Keat Tan

“…Autologous or allogeneic stem cells such as mesenchymal stem cells and induced pluripotent stem cells can be used for direct tissue treatment in a rapid, personalized, and efficient manner. This approach of engineering cells and altering their functions before clinical use offers numerous benefits that are essential for personal health.…”
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The Brain Behind the Grid: A Comprehensive Review on Advanced Control Strategies for Smart Energy Management Systems by Gowthamraj Rajendran, Reiko Raute, Cedric Caruana

“…This paper presents a systematic review of key digital technologies—such as artificial intelligence, the Internet of Things, blockchain, and digital twins—employed in AES, providing a critical assessment of their individual functionalities, interdependencies, and collective contributions to the energy sector. …”
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Performance Analysis and Computational Interface for <italic>X &#x2013; R</italic> Intuitionistic Fuzzy Control Chart by Amanda Dos Santos Mendes, Tulio S. Almeida, Marcela A. G. Machado, Paloma Maria Silva Rocha Rizol

“…This work showed that intuitionistic fuzzy control charts are efficient at detecting special causes, and that the computer interface developed is capable of performing the proposed functions.…”
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Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential by Niza Otero-Guzman, Ricardo Andrade-Pizarro

“…However, there are several challenges associted with the efficient extraction and accurate characterization of these compounds, including the complexity of plant matrices, variability in compound polarity, and the need for scalable, eco-friendly methods that preserve their bioactivity. …”
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Reference Intervals for Echocardiography Parameters of Children Living in the Arkhangelsk Region and a Digital Application for Their Assessment by Aleksey A Karyakin, Igor’ S. Chub, Ol’ga E. Karyakina, Andrey M. Grjibovski, Aleksey V. Artemov, Ul’yana R. Zakharchenko

“…Reference intervals of echocardiography parameters were determined using body surface area as the dependent variable. The values were automatically calculated in our digital application that allows one to increase the accuracy and efficiency of interpretation of cardiac ultrasound parameters. …”
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Response Surface Optimization of CuS Photocatalytic Process Using UV‐vis Irradiation for Wastewater Treatment by Caressa Munien, Emmanuel Kweinor Tetteh, Sudesh Rathilal

“…Thus, this study aimed to optimize the operating parameters of the photocatalytic degradation process using copper sulphide (CuS) and UV‐visible irradiation via response surface methodology (RSM) to determine the relationship that exists between the most significant factors and the water quality parameters. The efficiency of the CuS photocatalyst was evaluated as a function of three input variables viz. …”
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Expanding a Health Technology Solution to Address Therapist Challenges in Implementing Homework With Adult Clients: Mixed Methods Study by Brian E Bunnell, Kaitlyn R Schuler, Julia Ivanova, Lea Flynn, Janelle F Barrera, Jasmine Niazi, Dylan Turner, Brandon M Welch

“… BackgroundHomework is implemented with variable effectiveness in real-world therapy settings, indicating a need for innovative solutions to homework challenges. …”
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Impact of IgG subclass on monoclonal antibody developability by Paul Cain, Lihua Huang, Yu Tang, Victor Anguiano, Yiqing Feng

“…We thus conducted a systematic study of 12 mAbs derived from three sets of unrelated variable regions, each cloned into IgG1, an IgG1 variant with diminished effector functions, IgG2, and a stabilized IgG4 variant with further reduced FcγR interaction, to evaluate the impact of IgG subclass on manufacturability and high concentration stability in a common formulation buffer matrix. …”
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Study on the Photosynthetic Physiological Responses of Greenhouse Young Chinese Cabbage (<i>Brassica rapa</i> L. <i>Chinensis Group</i>) Affected by Particulate Matter Based on Hyp... by Lijuan Kong, Siyao Gao, Jianlei Qiao, Lina Zhou, Shuang Liu, Yue Yu, Haiye Yu

“…Particulate matter affects both the light environment and air quality in greenhouses, obstructing normal gas exchange and hindering efficient physiological activities such as photosynthesis. …”
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Application of machine learning and neural network models based on experimental evaluation of dissimilar resistance spot-welded joints between grade 2 titanium alloy and AISI 304 s... by Marwan T. Mezher, Alejandro Pereira, Rusul Ahmed Shakir, Tomasz Trzepieciński

“…The best prediction model was found to be the ANN model when training the conjugate gradient with the Polak-Ribiere updates (Traincgp) training function with the hyperbolic tangent sigmoid transfer function (Tansig) with the mean squared error (MSE) and correlation coefficient (R2) values recorded as 0.01886 and 0.94973, respectively. …”
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Arterial hypertension and myocardial electric heterogeneity in patients with coronary heart disease by L. A. Leshchinsky, B. L. Multanovsky, A. G. Petrov, S. B. Ponomarev

“…Myocardial electric heterogeneity, especially in PS, correlated with left ventricular (LV) hypertrophy, LV diastolic function, and the overall functional status of cardiovascular system. …”
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Organizational and Economic Factors of Health System Optimization by Oleksandr Telizhenko, Yuliia Halynska, Nataliia Baistriuchenko, Volodymyr Potseluiev, Kateryna Demchuk

“…To this aim, the factors that influence the efficiency of the organization and functioning of the medical system are identified. …”
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Evaluating Machine Learning Models for Predicting Hardness of AlCoCrCuFeNi High-Entropy Alloys by Uma Maheshwera Reddy Paturi, Muhammad Ishtiaq, Pasupuleti Lakshmi Narayana, Anoop Kumar Maurya, Seong-Woo Choi, Nagireddy Gari Subba Reddy

“…This study evaluates the predictive capabilities of various machine learning (ML) algorithms for estimating the hardness of AlCoCrCuFeNi high-entropy alloys (HEAs) based on their compositional variables. Among the ML methods explored, a backpropagation neural network (BPNN) model with a sigmoid activation function exhibited superior predictive accuracy compared to other algorithms. …”
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Meristic and morphometric comparison of an undescribed sucker of the Río Culiacán (Catostomus sp.) and Yaqui sucker (Catostomus bernardini) (Catostomidae, Teleostei) from the Sierr... by Gorgonio Ruiz-Campos, Sergio Sánchez-Gonzáles, Richard L. Mayden, Alejandro Varela-Romero

“…Likewise, the discrimination was associated with the lowest values for predorsal distance, soft posterior ocular margin to occiput, and number of anal rays. The standardized coefficients for canonical variables 1 and 2 accounted 82.6% of the total variation. …”
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Treatment of Pediatric Colchicine Poisoning with Single-Pass Albumin Dialysis: A Case Report by Atessa Bahadori, Rishil Patel, Cal Robinson, Steve Balgobin, Michael Zappitelli, Nithiakishna Selvathesan

“…The rationale for CVVHDF with SPAD was based on the high protein binding, variably high volume of distribution, previous reports showing a sieving coefficient of 0.2 with CVVH, and the high mortality risk. …”
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A Data-Driven Approach Based on Deep Neural Network Regression for Predicting the Compressive Strength of Steel Fiber Reinforced Concrete by Nhat-Duc Hoang, Van-Duc Tran

“…Experimental results show that the L1 regularization helps achieve the most desired performance, with a coefficient of determination (R2) of roughly 0.96. Notably, an asymmetric loss function is used along with Nadam to decrease the percentage of overestimated cases from 50.83% to 27.08%. …”
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Estimativa das temperaturas máximas e mínimas do ar para a região do Circuito das Frutas, SP Estimation of maximum and minimum air temperatures for the "Circuito das Frutas" region... by Ludmila Bardin, Mário J. Pedro Júnior, Jener F. L. de Moraes

“…Also, maps with the spacial variability of the maximum and minimum mean monthly and annual temperatures are presented for the region.…”
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The Effect of Vocal Rehabilitation on Patients with Vocal Cord Paralysis by Mila Bunijevac, Andrijana Mikić, Maša Đurišić

“…Measures of central tendency, measures of variability, one-factor analysis of variance, t-test for independent samples, chi-square test and interclass correlation coefficient were applied in statistical data processing. …”
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Sensitivity to Instruction Strategies in Motor Learning Is Predicted by Anterior–Posterior TMS Motor Thresholds by Michael L. Perrier, Kylee R. Graham, Jessica E. Vander Vaart, W. Richard Staines, Sean K. Meehan

“…Recent transcranial magnetic stimulation (TMS) studies suggest that variability in interneuron recruitment by anterior–posterior (AP) currents is linked to differences in functional connectivity between premotor and motor regions. …”
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