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Genetically surface-modified Escherichia coli outer membrane vesicles targeting MUC1 antigen in cancer cells
Published 2024-12-01“…In conclusion, this rapid and efficient bio-ligation system facilitates the display of functional scFv on OMV surfaces, offering a promising approach for targeted delivery to MUC1-expressing cancer cells.…”
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703
Exploring the optimal lower blood pressure boundary during endovascular thrombectomy in patients with large vessel occlusion
Published 2025-03-01“…No significant relationship was observed between DBP and functional outcomes. Patients with higher periprocedural SBP coefficient variance exhibited a decreased rate of good functional outcomes at 3 months (aOR, 0.42, 95% CI, 0.18–0.96). …”
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704
Discriminative Validity and Reliability of the Single-Leg Squat and Single-Leg Landing Frontal Plane Kinematics in Individuals with Lower Limb Functional Deficits
Published 2025-04-01“…It is necessary to identify variables and tests with adequate reliability and with the capability to discriminate individuals with and without lower limb functional deficits. …”
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705
Biochar and its impact on soil profile and plant development
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706
Optimizing hospital length of stay and bed allocation using a fuzzy stochastic transportation problem framework with lomax distribution,
Published 2025-06-01“…Additionally, the integration of fuzzy and stochastic elements led to a 20 . reduction in bed allocation mismatches, optimizing resource utilization across hospital departments. • Novel Integration of Lomax Distribution in FSTPWLD: Utilizes the Lomax distribution to model heavy-tailed LOS data, capturing inherent uncertainty and variability in hospital discharge times. • Optimized Decision-Making for Healthcare Management: Employs probabilistic constraints and fuzzy stochastic models to balance operational costs and patient care quality, improving resource allocation. • Validated through Simulations and Practical Scenarios: Numerical experiments highlight the model's effectiveness in reducing bottlenecks and enhancing hospital administration efficiency.…”
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707
Main indicators of the credit organizations of the Russian Federation: vectors of changes
Published 2017-05-01“…In recent years, changes in the structure of the banking system and the profi tability of operations conducted by banks. Analysis of the functioning of the system shows a reduced role of banking indicators in the formation of the Russian GDP. …”
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708
Different whole body HIIT protocols do not promote different muscle thickness and functional adaptations among healthy physically active subjects
Published 2025-01-01“…Morphological (ultrasound-derived muscle thickness of the vastus lateralis [MTVL]) and general fitness (muscle endurance and maximal oxygen consumption) assessments were performed at pre- and post-intervention moments.ResultsBoth training protocols elicited significant improvements in all dependent variables (p < 0.05), with no significant between-group differences.ConclusionRegardless of the training configuration, both WB-HIIT programs serve as time-efficient strategies to induce changes in muscle thickness of the vastus lateralis and functional adaptations in healthy, physically active young individuals.…”
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709
Deterministic Calculation Method for Continuous-energy Neutron Transport Equation in No-resonance Energy-range
Published 2024-06-01“…In order to eliminate the multi-group approximation in the deterministic method, a method for calculating neutron transport equation in the non-resonant energy region based on function expansion was proposed. Initially, the non-resonant energy region was subdivided into segments, and within each segment, orthogonal polynomials serve as base functions for expanding the neutron flux density, which realized the processing of single energy independent variable in the neutron flight and absorption process, as well as the handling of double energy independent variable in the neutron scattering process. …”
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710
The effect of early childhood stature on later cognitive functions in Indonesian adolescents: comparation using the National growth reference and the WHO growth standard
Published 2025-06-01“…In adolescence, cognitive function were assessed. An analysis was performed to assess the associations between variables. …”
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711
Exposure-response functions of the correlated environmental exposures green space, noise, and air pollution for quantifying mortality burden in health impact assessment
Published 2025-08-01“…The studies show substantial variability in exposure levels and correlations between exposures. …”
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712
The association between TNF-receptors (TNFR1 and TNFR2) and mortality as well as kidney function decline in patients with chronic kidney disease
Published 2024-11-01“…Differences in eGFR decline in relation to plasma TNFR1 and TNFR2 were estimated by both linear and logistic regression models, with regression coefficients and odds ratios (ORs). Results: Univariate models showed significant associations between TNFR1 (n = 985) and TNFR2 (n = 988) and all-cause mortality based on 7424 person-years at risk, but in the fully adjusted models with continuous variables significant only for TNFR2 HR 1.17 (1.03–1.34), but with a borderline value for TNFR1 HR 1.15 (1.00–1.31). …”
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713
Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and intervention
Published 2025-04-01“…Dynamic functional connectivity studies report reduced brain activity efficiency, while graph theory analyses show decreased network integration. …”
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714
Direct methanol fuel cells parameter identification with enhanced algorithmic technique
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715
Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke
Published 2023-06-01“…Automated assessment of upper extremity motor function based on machine learning algorithms with markerless sensing techniques has focused on the Fugl-Meyer assessment of upper extremity (FMA-UE), Brunnstrom stages, and Wolf motor function test (WMFT) scales and has been proved with high-scoring accuracy and time efficiency. …”
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716
Eficiência técnica na suinocultura: efeitos dos gastos com meio ambiente e da renúncia fiscal Technical efficiency in swine breeding: effect of the expenses with the environment an...
Published 2008-04-01“…After estimating the technical efficiency indices with data of ten properties situated in Mato Grosso from production functions, whose dependent variable is represented by the production of swine and the independent ones are the consumption of water, electricity and the amount of workers directly tied with the productive process. …”
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717
Sensitivity Analysis of Numerical Coherency Model for Rock Sites
Published 2025-03-01“…Because of difficulties in developing an empirical coherency function from a site-specific dense array, it is seldom used in practice. …”
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Evaluating the effects of urban development on the ecological carrying capacity of Isfahan city based on the system dynamics approach
Published 2023-09-01“…In order to validate the model, the historical trend and simulation of two variables of urban population and the number of industries have been compared using the coefficient of determination.Results and discussion: The pressure factors on the urban carrying capacity were detected and analyzed by assessing key variables in the system, such as water sustainability (WSI) and air quality, as well as changes in the landscape structure of Isfahan using landscape metrics. …”
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Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.
Published 2013-01-01“…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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