Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer by Lei Shi, Lei Shi, Lei Shi, Xuyang Zhong, Jiafeng Liu, Yong Ying, Zibing Liao, Jin Liu, Liwen Zhao, Jianing Zhong, Jianing Zhong, Xiangtai Zeng, Xiangtai Zeng

“…We systematically dissect the multifaceted regulatory circuits governing lactate metabolism by integrating three pivotal dimensions: (i) canonical signaling cascades; (ii) tumor-microenvironmental variables, most notably hypoxia and acidosis; and (iii) the emerging epigenetic paradigm of lactylation, which dynamically reprograms the catalytic efficiency of rate-limiting enzymes and reshapes the transcriptional landscape of metabolic genes, thereby precisely coordinating lactate homeostasis. …”
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Comparative Evaluation of Vibratory Physiotherapy Methods in the Early Period after Cardiac Surgery by А. А. Eremenko, T. P. Zyulyaeva, D. V., Ryabova, А. P. Аlferova

“…Mechanical respiratory therapy procedures led to significant improvement in gas exchange variables, as evidenced by an increase in SpO2 in Groups 1 and 2 (p = 0.000009 and 0.000001, respectively) and a decrease in the proportion of patients with impaired oxygenating lung function (SpO2 below 92%) by 11 and 12 times, respectively (p < 0.01). …”
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Modeling of Ozone Interactions with Various Air Pollutants and Meteorological Factors Using Jaya and Teaching-Learning Based Optimization (TLBO) Algorithms by Nurcan Öztürk

“…In conclusion, it is shown that Jaya and TLBO algorithms can be used in the optimization of the regression function coefficients in modelling some air pollutants interactions and the best-fit equation for each parameter is obtained from the quadratic function.…”
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ANALYSIS OF PATH NONPARAMETRIC TRUNCATED SPLINE MAXIMUM CUBIC ORDER IN BANKING CREDIT OF RISK BEHAVIOR MODEL by Devi Veda Amanda, Atiek Iriany, Adji Achmad Rinaldo Fernandes, Solimun Solimun

“…Based on the results of the analysis, it is known that the best-truncated spline nonparametric path model is the quadratic order of 2 knots with a coefficient of determination of 85.50%; the significance of the best-truncated spline nonparametric path estimator shows that all exogenous variables have a significant effect on endogenous variables.…”
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Good Governance and Seigniorage in a Selected OPEC Countries and Iran by ALI Rashid Shamkhal, Kambiz Paykarjou, beitollah Akbari Moghaddam

“…Good governance has several positive effects on government revenues and efficiency. While the use of seigniorage may initially appear as a natural right of governments, if it leads to a faster growth rate of money compared to economic growth, it can result in inflation and impose inflationary taxes. …”
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Dimensions-Reduced Volterra Digital Pre-Distortion Based On Orthogonal Basis for Band-Limited Nonlinear Opto-Electronic Components by Hananel Faig, Yaron Yoffe, Eyal Wohlgemuth, Dan Sadot

“…However, naive implementation of the Volterra polynomial model usually introduces significant complexity due to the large number of model coefficients. Here, we propose the use of orthogonal polynomial basis functions for efficient DPD implementation. …”
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The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review by Stanisław Dudek, Weronika Koziak, Aleksandra Bętkowska, Agata Kornacka, Kamila Szostak, Rafał Tomaka, Michalina Makieła, Wojciech Dudek, Anna Byra

“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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On a Solution of a Third Kind Mixed Integro-Differential Equation with Singular Kernel Using Orthogonal Polynomial Method by Ahmad Alalyani, M. A. Abdou, M. Basseem

“…While when using the separation method, we are able to obtain FIE with time coefficients, and these functions are described as an integral operator in time. …”
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THE TEMPERATURE DEPENDENCE OF UNSTEADY HEAT CONDUCTION IN SOLIDS by L. M. Ozherelkova, E. S. Savin

“…Both in the case of high and low temperatures, the temperature dependences of the heat capacity and the thermal conductivity coefficient are power-law, which allows us to bring the original heat conduction equation to a form that allows the use of the classical method of variable separation in solving the corresponding boundary value problems for the heat conduction equation. …”
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Mechanical Impedance Control in the Human Arm While Manually Transporting an Open-Top Fluid Filled Dish by Navit Roth, Rami Seliktar, Joseph Mizrahi

“…The function used for damping included first-order dependence on angular velocity. …”
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Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Importantly, not all types of aluminosilicates have the same decontaminating efficiency; thus, a full characterization of the protective properties of each single material would assist in selecting the most appropriate binder. …”
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AngleCam: Predicting the temporal variation of leaf angle distributions from image series with deep learning by Teja Kattenborn, Ronny Richter, Claudia Guimarães‐Steinicke, Hannes Feilhauer, Christian Wirth

“…The plausibility of the predicted leaf angle time series was underlined by its close relationship with environmental variables related to transpiration. The evaluations confirm that AngleCam is a robust and efficient method to track leaf angles under field conditions. …”
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Intelligent wearable devices with audio collection capabilities to assess chronic obstructive pulmonary disease severity by Chunbo Zhang, Kunyao Yu, Zhe Jin, Yingcong Bao, Cheng Zhang, Jiping Liao, Guangfa Wang

“…A logistic regression model using the RR and blowing sounds as key predictors achieved accuracies of 0.77–0.89 in determining the GOLD grade, with a Cohen's kappa coefficient of 0.6757. Conclusions Audio data were more strongly correlated with lung function in COPD patients than were physiological parameters. …”
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Fractional Dynamics of Laser-Induced Heat Transfer in Metallic Thin Films: Analytical Approach by M. A. I. Essawy, Reham A. Rezk, Ayman M. Mostafa

“…Dynamic profiles demonstrate the responsiveness of heat transfer to thermal and optical variables. The innovation resides in the meticulous analytical formulation utilizing a realistic laser source, the clear significance of the absorption parameter that enhances the temperature amplitude, the incorporation of the Mittag–Leffler function, and a comprehensive investigation of fractional photothermal effects in metallic nano-systems. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery by Justin E. Kung, Chase Gauthier, Yianni Bakaes, Michael Spitnale, Richard A. Bidwell, David G. Edelman, Heidi C. Ventresca, J. Benjamin Jackson, Shari Cui, Gregory Grabowski

“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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Dynamic Stability of a Circular Pre-Stressed Elastic Orthotropic Plate Subjected to Shock Excitation by Yuriy A. Rossikhin, Marina V. Shitikova

“…Behind the fronts of these waves, the solution is constructed in terms of ray series, which coefficients are the different order discontinuities in partial time-derivatives of the desired functions, and a variable is the time elapsed after the wave arrival at the plate’s point under consideration. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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Fiscal Sustainability in Iran A Markov-Switching Fiscal Regime Change and Time-Varying Parameter Models Approach by Hossein Aghilifar, Khosrow Piraei, Hashem Zare, Mehrzad Ebrahimi

“…Then the Markov-switching fiscal regime change model and the time-varying parameter fiscal reaction function are estimated. Among the constant parameter linear and non-linear models, only the linear model including control variables has a significant debt-to-GDP ratio coefficient, which its sign is negative. …”
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