Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues. by Giuseppe Orsomando, Lucia Cialabrini, Adolfo Amici, Francesca Mazzola, Silverio Ruggieri, Laura Conforti, Lucie Janeckova, Michael P Coleman, Giulio Magni

“…Final assay validation was achieved in a tissue extract by comparing the activity and expression levels of individual isozymes, considering their distinctive catalytic efficiencies. Furthermore, considering the key role played by NMNAT activity in preserving axon integrity and physiological function, this assay procedure was applied to both liver and brain extracts from wild-type and Wallerian degeneration slow (Wld(S)) mouse. …”
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Implementasi Indonesia National Single Window (INSW): Suatu pendekatan Business Intelligence System (BIS) by Muhammad Ibnu Fajar, Arief Rahman

“…Meanwhile, the dependent variable includes the implementation of Indonesia National Single Window (INSW) by Business Intelligence System (BIS) approach. …”
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Statistical mechanics of dynamical system identification by Andrei A. Klishin, Joseph Bakarji, J. Nathan Kutz, Krithika Manohar

“…To establish this analogy, we define the hyperparameter optimization procedure as a two-level Bayesian inference problem that separates variable selection from coefficient inference and enables the computation of the posterior parameter distribution in closed form. …”
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Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. by Keiko Miyadera, Ian Brierley, Jesús Aguirre-Hernández, Cathryn S Mellersh, David R Sargan

“…Variable polyA(n) length was confirmed in DNA from different RPGRIP1(-/-) dogs, yet polyA(n) variability did not correspond with the clinical phenotypes and no individual was found that carried a polyA(n) tract capable of encoding an in-frame variant. …”
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Sparse Learning of the Disease Severity Score for High-Dimensional Data by Ivan Stojkovic, Zoran Obradovic

“…This problem is solved by addressing a dual formulation which is smooth and allows an efficient optimization. The proposed approach might be used as an effective and reliable tool for both scoring function learning and biomarker discovery, as demonstrated by identifying a stable set of genes related to influenza symptoms’ severity, which are enriched in immune-related processes.…”
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Non-destructive textural quality assessment of peaches and nectarines using near-infrared spectroscopy integration time by Eva Cristina Correa, Paola Baltazar, Pilar Barreiro, Natalia Hernández-Sánchez, Lourdes Lleó, Ángela Melado-Herreros, Belén Diezma

“…A principal component analysis (PCA) was used to analyze textural variability, and discriminant function analysis (DFA) and artificial neural networks (ANNs) were applied to classify fruit firmness levels.PCA effectively defined a new variable, PC1, that captured the variance in fruit texture, correlating positively with juiciness and negatively with firmness. …”
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Random First-Order Linear Discrete Models and Their Probabilistic Solution: A Comprehensive Study by M.-C. Casabán, J.-C. Cortés, J.-V. Romero, M.-D. Roselló

“…The study is based on Random Variable Transformation method. The obtained results are given in terms of the probability density functions of the data, namely, initial condition, forcing term, and diffusion coefficient. …”
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An Analysis of Influential Factors in the Use of Public Bicycles in Tehran by Ehsan Faghihi, Mojtaba Rafieian

“…So far, many researches have been conducted on the components affecting the functional stability of the shared bicycles system, for example Si et al. in 2020 found that factors of efficiency, economic benefits, environmental awareness, and infrastructure incentives influence the willingness to use the shared bicycle system. …”
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Contribution of entropy analysis on three-dimensional Prandtl model under Hall and ion slip effects with generalized mass and heat fluxes via OHAM by Sana Akbar, Muhammad Sohail, Syed Tehseen Abbas, Abha Singh

“…This article also examined the combined impacts of thermal conductivity change together with variable mass diffusion co-efficient within the heat and mass transport in the occurrence of Prandtl fluid. …”
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Spatial dependencies between large-scale brain networks. by Robert Leech, Gregory Scott, Robin Carhart-Harris, Federico Turkheimer, Simon D Taylor-Robinson, David J Sharp

“…Many studies show a temporal relationship between task positive and task negative networks that is important for efficient cognitive functioning. Here we provide evidence for a spatial relationship between task positive and negative networks. …”
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Weather Phenomena Monitoring: Optimizing Solar Irradiance Forecasting With Temporal Fusion Transformer by Xinyang Hu

“…The proposed model decomposes the raw solar irradiance sequence into intrinsic mode functions using VMD and optimizes the TFT using the variable screening network and GRU-based encoder-decoder. …”
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Optimizing Constrained Engineering Optimization Problems Using Improved Mountain Gazelle Optimizer by Vu Hong Son Pham, Nghiep Trinh Nguyen Dang, Van Nam Nguyen

“…These enhancements underscore the significant potential of iMGO in real-world applications across aerospace engineering, structural design optimization, energy system planning, and other fields, thereby contributing to more efficient and sustainable engineering solutions.…”
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APPLICATION OF HYBRID RANDOM SEARCH METHOD TO OPTIMISATION OF ENGINEERING SYSTEMS’ PARAMETERS by A. V. Panteleev, D. A. Rodionova

“…These problems belong to the class of constrained global optimization problems, where the level surface of the objective function has uneven relief and there is a large number of variables. …”
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Handwritten Words Image Character Extraction Adaptive Algorithm Based on the Multi-branch Structure by GUO Xiaojing, ZHAO Xiaoyuan, ZOU Songlin

“…Higher identification precision and efficiency serve as reference indices for evaluating the model. …”
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Hybrid data-driven and physics-informed regularized learning of cyclic plasticity with neural networks by Stefan Hildebrand, Sandra Klinge

“…The mean squared error is assumed as the loss function which stipulates several restrictions: deviatoric character of internal variables, compliance with the flow rule, the differentiation of elastic and plastic steps and the associativity of the flow rule. …”
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Optimization Design of Fast Neutron Target Station Beam Extraction Based on Genetic Algorithm by QIN Ziqian1, 2, 3, TAN Xinjian2, 3, ZHANG Xiaodong2, 3, PAN Qingquan1, LIU Xiao2, 3

“…Therefore, the aforementioned parameters are used as variables, and the three important indicators are taken as the objective function. …”
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Synthesis of evasive maneuver control of unmanned aerial vehicle for terminal restrictions by N. Y. Polovinchuk, S. V. Ivanov, L. I. Kotelnitskaya

“…The FV (flying vehicle) control is organized with maximum efficiency. Herewith, the maneuvering FV trajectory must satisfy the requirements of optimality for some given functions of the phase variables at the final time and the conditions of its path through a specified terminal area space. …”
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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries by Keith Mitchell, Samuel Hunter, Lutz Froenicke, Karl Murray, Matthew Settles, James S. Trimmer

“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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ANALYSIS AND OPTIMIZATION OF QUICK-RETURN CHARACTERISTICS OF THE BEATING⁃UP SLEY BASED ON MULTIVARIABLE DESIGN by QIU HaiFei

“…For improving the quick‑return characteristics of the sley movement,an optimal mathematical model for maximum curve displacement Sm of the connectingarm pin was proposed through beating‑up principle analysis and mechanism deduction.A multivariable design space was constructed by use of the component length(lc,lh,lr,lf)and crankangleα.The parametric functional model development of the four‑bar beating‑up with short connecting rod was realized,and its kinematic posture and centroid trajectory were analyzed and verified through mechanism simulation.The results of the case study indicate that the variable lc andαhave more greater influence on the sensitivity of the objective function F(X),and multivariable(DV_1,DV_2,DV_3)coupling can effectively enhance the design plasticity of the quick‑return characteristics of the sley.When the maximum curve displacement Sm of the connectingarm pin increases to 71.41 mm,the extreme position angleθand the travel speed ratio coefficient K are increased by 10.96°and 0.131 respectively,and the quick-return motion effect of the sley is obviously improved.The optimization results accord with the conditions of rod length and mechanism transmission requirement,which are conductive to the design innovation and performance improvement of the four‑bar beating‑up system.…”
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Faktor-Faktor Yang Mempengaruhi Pertumbuhan Ekonomi Di Jawa Timur Dengan Pendekatan Spatial Regression by Rendra Erdkhadifa

“…The research results show that the weighting function used is fixed gaussian, and the spatial model has a coefficient of determination of 92.97%. …”
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