Impact of IgG subclass on monoclonal antibody developability by Paul Cain, Lihua Huang, Yu Tang, Victor Anguiano, Yiqing Feng

“…We thus conducted a systematic study of 12 mAbs derived from three sets of unrelated variable regions, each cloned into IgG1, an IgG1 variant with diminished effector functions, IgG2, and a stabilized IgG4 variant with further reduced FcγR interaction, to evaluate the impact of IgG subclass on manufacturability and high concentration stability in a common formulation buffer matrix. …”
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Evaluating the Effectiveness of Quality Control Measures in Project Management: A Study of Construction Companies in Lusaka by Mwanza Jacob, Chimbomba Kelvin

“…Quality control measures implemented in project management functions of construction companies function as essential elements which support project achievement, client fulfillment, and business endurance. …”
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Optimal Dispatch of Power System with P2G-Wind-Thermal-Nuclear-Carbon Capture Units by Wenhao CHAO, Zhi YUAN, Ji LI

“…In this paper, a linearized peaking depth model for nuclear units is proposed considering their co-operation with power-to-gas (P2G), WPG, thermal, and carbon capture units. …”
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Incorporating Traffic Flow Model into A Deep Learning Method for Traffic State Estimation: A Hybrid Stepwise Modeling Framework by Yuyan Annie Pan, Jifu Guo, Yanyan Chen, Siyang Li, Wenhao Li

“…The model-driven method is commonly used to solve TSE efficiently and calibrate the parameters of these models. …”
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A De-Nesting Hybrid Reliability Analysis Method and Its Application in Marine Structure by Chenfeng Li, Tenglong Jin, Zequan Chen, Guanchen Wei

“…Traditional methods for hybrid reliability analysis usually require a nested optimization framework, which will lead to too many calls to the limit state function (LSF) and result in poor computational efficiency. …”
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Parameter Sensitivity Analysis and Algorithm Improvement of Optimization Scheduling Model for Cascade Pumping Stations by LIU Xiaolian, LI Zhenrong, WANG Xue-ni, ZHAI Yu, ZHANG Lei-ke, GUO Weiwei, TIAN Yu

“…Additionally, a Tent boundary mapping strategy was employed to regenerate the boundary value, resulting in improved the optimization efficiency of RUN. Six benchmark functions, including unimodal, multimodal and fixed dimension, were used to verify the performance and improvement strategies of TRUN. …”
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Class Precarity and Solidarity in Education by Abdul Aziz Hafiz

“…The aim is to ground prosociality in co-operative social and educational practices rooted in the conscientisation of social and solidarity economy. …”
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A robust audio steganography algorithm based on differential evolution by Zhaopin SU, Chaoyong SHEN, Guofu ZHANG, Feng YUE, Donghui HU

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Class Precarity and Solidarity in Education by Abdul Aziz Hafiz

“…The aim is to ground prosociality in co-operative social and educational practices rooted in the conscientisation of social and solidarity economy. …”
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ANALYSIS OF CLIMATE-RELATED RISK AND MAIZE PRODUCTION IN SOUTHWEST, NIGERIA by Lawrence Olusola OPARINDE, Emmanuel Chilekwu OKOGBUE

“…Secondary data between 1981 and 2012 were collected on relevant variables and analysed using Growth Function, Co-integration Model (Autoregressive Distributed Lag Approach) and J-P Model. …”
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Versatile machine learning algorithms for FTIR spectroscopy: differentiating crosslinked and non-crosslinked gelatin samples by Juliana Rincón-López, Eliana Álvarez-Valdés, Daniela Velez-Arango, Estefanía Rojas Zuleta, Leidy Yuliana Vargas Soto, Liliana Lellesch, Victor Alonso García Londoño, Milton Rosero-Moreano, Gonzalo Taborda-Ocampo

“…The functional and mechanical properties of the gelatin depend on the chemical and structural characteristics. …”
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The Effect of Hydraulic Partitioning on Prediction the Rate of Bed Load Transport in Gravel-bed Rivers using Support Vector Machine by Kiyoumars Roushangar, Mohammad Hosseini, Saman Shahnazi

“…Prediction ability of bed load transport is variable due to complexities that governs fluvial sediment transport in different flow conditions. …”
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Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters by E. B. Myakoshina, I. G. Kulikova, N. V. Balatskaya, L. A. Katargina, S. V. Saakyan

“…A formula was calculated where P (z) is the value of the logistic function; Z, linear combination of symptoms; bo , intercept (free term), bi – regression coefficients for parameters Zi.P (z) = 1 : 1 + e – b0– b1z1– b2z2– b3z3– b4z4The logistic function increases monotonically and takes the values from 0 to 1 for any b and Z values [P∈ (0;1)]. …”
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Protein expression profiling identifies a prognostic model for ovarian cancer by Luyang Xiong, Jiahong Tan, Yuchen Feng, Daoqi Wang, Xudong Liu, Yun Feng, Shusheng Li

“…The prognostic effect and the biological function of the model were evaluated using co-expression analysis and enrichment analysis. …”
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Large live biomass carbon losses from droughts in the northern temperate ecosystems during 2016-2022 by Xiaojun Li, Philippe Ciais, Rasmus Fensholt, Jérome Chave, Stephen Sitch, Josep G. Canadell, Martin Brandt, Lei Fan, Xiangming Xiao, Shengli Tao, Huan Wang, Clément Albergel, Hui Yang, Frédéric Frappart, Mengjia Wang, Ana Bastos, Philippe Maisongrande, Yuanwei Qin, Zanpin Xing, Tianxiang Cui, Ling Yu, Lei He, Yi Zheng, Xiangzhuo Liu, Yuqing Liu, Aurelien De Truchis, Jean-Pierre Wigneron

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Reconfiguration of dynamic brain networks in heart failure with preserved ejection fraction: Linking neurovascular coupling and cardiac dysfunction by Xiulin Liang, Qinghua Zhang, Chuanlong Zhang, Jingjing Liu, Pengcheng Sang, Qing Mao, Lei Wang

“…Results: (1) Static network topology properties exhibited significantly decreased local network efficiency among patients with HFpEF. The connectivity strength and information processing efficiency were diminished in the left parahippocampal gyrus, left cingulate gyrus, and right insular gyrus brain regions, and improved in the left thalamus, right fusiform gyrus, and right precuneus regions. (2) Dynamic network topology properties of patients with HFpEF showed decreased variability in critical nodes and brain subregions (e.g., the superior frontal gyrus, left amygdala, and left fusiform gyrus) and compensatory increases in the variability of specific regions (e.g., right insular gyrus, right postcentral gyrus, and right temporal gyrus). (3) In HFpEF, the static and dynamic functional brain network topology properties of the fusiform gyrus, cingulate gyrus, superior temporal gyrus, precuneus, parahippocampal gyrus, insular gyrus, and amygdala regions were significantly correlated with cardiac structural and functional indices, such as LVDd, LVMI, and E/e′ ratio. …”
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Optimization of fermentation conditions for enhanced acetylcholine and biomass production of Lactiplantibacillus plantarum AM2 using the Taguchi approach by Walid A. Lotfy, Amira M. Ali, Heba M. Abdou, Khaled M. Ghanem

“…Abstract This study aimed to optimize the fermentation conditions and medium composition for maximum acetylcholine (ACh) and biomass production by Lactiplantibacillus plantarum AM2 using the Taguchi array design, which enables efficient identification of influential variables through minimal experimental runs. …”
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Organizational and Economic Factors of Health System Optimization by Oleksandr Telizhenko, Yuliia Halynska, Nataliia Baistriuchenko, Volodymyr Potseluiev, Kateryna Demchuk

“…To this aim, the factors that influence the efficiency of the organization and functioning of the medical system are identified. …”
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Energy optimization through morphing blade design under structural constraints: a case study on the NREL 1.5 MW wind turbine by Najafian Arezoo, Jahangirian Alireza

“…These findings underline the potential of morphing blade technologies to enhance energy efficiency in wind turbines while adhering to practical structural limitations.…”
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Effects of SGLT2 inhibitors on cardiac autonomic activity and ventricular remodeling in patients with acute myocardial infarction: study protocol for a clinical trial by Jun Wan, Qinglong Zhang, Feng Xu, Xin Jiang, Cai Chen, Xiaodong Pan, Jinglin Cheng, He Li

“…Abstract Background Sodium-glucose co-transporter 2 inhibitors (SGLT2-I) exhibit significant cardiovascular protective effects in patients with acute myocardial infarction (AMI) complicated with type 2 diabetes mellitus (T2DM), mainly through enhancing cardiac function and reducing malignant arrhythmias. …”
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