Transcriptome analysis to decipher the molecular underpinnings of response to treatment in systemic lupus erythematosus by Dimitrios T Boumpas, Antonis Fanouriakis, George Bertsias, Dionysis Nikolopoulos, Aggelos Banos, Anastasia Filia, Antigone Pieta, Sofia Flouda, Katerina Chavatza, Panagiotis Garantziotis, Spyridon Katechis, Noemin Kapsala, George Sentis, Georgia Savina Moysidou, Nikos Malissovas

“…We identified differentially expressed genes and co-expressed transcript modules.Results Achieving response, irrespective of treatment, was accompanied by downregulation of B cell immunity-related and complement activation-related signatures. …”
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IGF2BP3 promotes autophagy-mediated TNBC metastasis via m6A-dependent, cap-independent c-Met translation by Zi-Wen Wang, Yi-Han Li, Meng-Yuan Cai, Xu Zhang, Ruo-Xi Xu, Hai-Yan Yang, Yu-Zhou Huang, Liang Shi, Ji-Fu Wei, Qiang Ding

“…Methylated RNA immunoprecipitation sequencing, luciferase assays and co-immunoprecipitation mass spectrometry showed that IGF2BP3 promoted mRNA translation initiation in an N6-methyladenosine (m6A)-dependent manner. …”
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VHR Multispectral Satellite Image Classification with Kolmogorov-Arnold Networks for Urban Applications by M. Fawzy, M. Fawzy, Á. Barsi

“…The Kolmogorov-Arnold Network (KAN) is a computational framework rooted in the Kolmogorov-Arnold representation theorem, which states that any continuous function of multiple variables can be expressed as a superposition of univariate functions. …”
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Insights into the Estimation of the Enhanced Thermal Conductivity of Phase Change Material-Containing Oxide Nanoparticles using Gaussian Process Regression Method by Tzu-Chia Chen, Hasan Sh. Majdi, Aras Masood Ismael, Jamshid Pouresmi, Danial Ahangari, Saja Mohammed Noori

“…In the following, a sensitivity analysis (SA) is used to explore the effectiveness of variables in terms of outputs and shows that the temperature (T) of nanofluid (NF) is the most efficient input parameter. …”
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Bankruptcy rules and sustainable water management: A MODSIM-NSGAII simulation multi-objective optimization framework for equitable transboundary water allocation by Bentolhoda Asl-Rousta, S. Jamshid Mousavi

“…This study addresses these challenges by introducing a new optimal bankruptcy rule (OpPro rule) through a simulation-optimization model (MODSIM-NSGAII), where MODSIM simulates the spatial and temporal variability of water resources, and the NSGA-II optimization algorithm includes two objective functions of maximizing basin-wide ecological sustainability and maximizing economic efficiency reflecting ''equitable and reasonable utilization'' of water. …”
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Ridge regression and its applications in genetic studies. by M Arashi, M Roozbeh, N A Hamzah, M Gasparini

“…On the other hand, the efficiency of the rank ridge regression estimator is highly dependent on the ridge parameter. …”
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System Modeling to Optimize the Production Quantity of Men's and Women's Jackets and Achieve Maximum Profit: A Case Study at Konveksi ABC Cikarang Using Linear Programming by Wisnu Aji

“…The objective function is designed to maximize profit, and the model is solved using IBM ILOG CPLEX software. …”
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State Identification of Charging Module Based on SN‐EMD‐SSEE and DBO‐HKELM by Bingyu Li, Xianhai Pang, Xuhao Du, Ziwen Cai

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Solid-state analog of gravitational redshift: Transport signatures of massless Dirac fermions in tilted Dirac cone heterostructures by Marziyeh Karmand, Mohsen Amini, Morteza Soltani, Ebrahim Ghanbari-Adivi, Seyed Akbar Jafari

“…A Dirac electron passing through a heterojunction with spatially variable tilt experiences an effective curved spacetime. …”
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Fault localization for automatic train operation based on the adaptive error locating array algorithm by Yanpeng Zhang, Yuxiang Cao

“…The research results can offer useful guidance for verifying the integrity and reliability of the ATO function and contribute to the intrinsic safety for rail transit.…”
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Modeling the Short-Term Effect of Traffic and Meteorology on Air Pollution in Turin with Generalized Additive Models by Pancrazio Bertaccini, Vanja Dukic, Rosaria Ignaccolo

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Two-Echelon Location-Routing Problem with Fuzzy Demand of Rural E-Commerce Logistics by Xiaojuan LU, Jianjun WANG, Shuai WU, Shiyu ZHENG, Qian LIU

“…Considering fuzzy demand, government subsidies and simultaneous delivery, the objective function aims to maximise the profit of enterprises considering government subsidies. …”
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A nomogram for diagnosis of BI-RADS 4 breast nodules based on three-dimensional volume ultrasound by Xianping Jiang, Chen Chen, Jincao Yao, Liping Wang, Chen Yang, Wei Li, Di Ou, Zhiyan Jin, Yuanzhen Liu, Chanjuan Peng, Yifan Wang, Dong Xu

“…It can function as a relatively accurate predictive tool for sonographers and clinicians and is therefore clinically useful. …”
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Stress Estimation Based on Stochastic Method for Strength Evaluation of Floating Wind Turbines by Byungmo Kim, Beomil Kim

“…Through further research, it is expected that the optimal analysis time for estimating MPM stress can be determined, allowing for efficient structural integrity assessment for FOWT.…”
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Analysis of value-based healthcare (VBHC) framework by incremental cost-effectiveness of surgical and therapeutic interventions: a retrospective study at tertiary private health gr... by Mona Khamis, Zainab Almoosa, Marie Santos, Engineer Diaa Kamal, Suhail Yaghmor, Muhammad Daniyal, Abbas Al Mutair

“…Abstract Background Rising healthcare costs have led to the adoption of value-based healthcare (VBHC), emphasizing patient outcomes and cost efficiency. This study evaluates VBHC in a tertiary private health group, focusing on cost-effectiveness using the median incremental cost-effectiveness ratio (ICER). …”
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Topologic Reorganization of White Matter Connectivity Networks in Early-Blind Adolescents by Zhifeng Zhou, Long Qian, Jinping Xu, Yumin Lu, Fen Hou, Jingyi Zhou, Jinpei Luo, Gangqiang Hou, Wentao Jiang, Hengguo Li, Xia Liu

“…Moreover, decreased regional efficiency and increased nodal path length in some visual and default-mode areas were strongly associated with the period of blindness in EBA cohort, suggesting that the function of these areas would gradually weaken in the early-blind brains. …”
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Research on Constraint Processing Method of High-dimensional Optimization Operation Problem of Cascade Reservoirs by Zhongzheng HE, Shuliang LI, Wei HUANG, Feng YAN, Jisi FU, bin XIONG

“…The intelligent optimization algorithm is a multidimensional linkage random search, which boasts a vast optimization space but suffers from low optimization efficiency. Therefore, this study introduces a constraint processing approach that integrates a penalty function with nested DPSA–POA and intelligent algorithms and applies it to the optimal flood control operation problem of cascade reservoirs in the middle reaches of the Ganjiang River, with decision variables extending to 2196 dimensions. …”
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Role of physical activity on the maintenance of cognition and activities of daily living in elderly with Alzheimer's disease Papel da atividade física na manutenção da cognição e a... by Cynthia Arcoverde, Andréa Deslandes, Aryce Rangel, Andreza Rangel, Robson Pavão, Fortunée Nigri, Eliasz Engelhardt, Jerson Laks

“…BACKGROUND: The practice of physical activities has proved to be an efficient strategy in the improvement of independency and cognitive functions in the elderly with Alzheimer's disease (AD). …”
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An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy by Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan

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Collaborative Federated Learning of Unmanned Aerial Vehicles in Space–Air–Ground Integrated Network by Huibo Li, Peng Gong, Siqi Li, Weidong Wang, Yu Liu, Xiang Gao, Dapeng Oliver Wu, Duk Kyung Kim, Guangwei Zhang, Jihao Zhang

“…In addition, the closed-form solutions of the optimized variables are obtained. Simulation results demonstrate that the proposed collaborative training scheme based on D2D can reduce the impact of heterogeneity on FL model performance and IRA can effectively reduce energy consumption while simultaneously enhancing training efficiency of FL.…”
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