Functional improvement of natural Saccharomyces cerevisiae yeast strains by cell surface molecular engineering by Sara Granuzzo, Monica Rossetto, Lucio Zennaro, Francesca Righetto, Paolo Antoniali, Raffaele Lopreiato

“…Abstract Background Cellular boundaries of microorganisms can be modified by the expression in the cell wall of specific proteins endowed with relevant properties, improving their functional performance. So far, the surface display (SD) technique had been widely employed in the yeast Saccharomyces cerevisiae, but it was limited to few laboratory strains and never explored in sauvage strains, i.e., isolated from natural environment, which are featured by higher levels of genetic variability, leading to peculiar phenotypic traits of possible advantage in biotechnology. …”
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A New Approach to Topology Optimization with Genetic Algorithm and Parameterization Level Set Function by Igor Pehnec, Damir Sedlar, Ivo Marinic-Kragic, Damir Vučina

“…Using the B-spline interpolation function, the number of variables describing the level set function was decreased, enabling the application of evolutionary methods (genetic algorithms) in the topology optimization process. …”
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Modulation of Thermospheric Circulation by Lower‐Thermospheric Winter‐to‐Summer Circulation: The Atmosphere Gear Effect by Jack C. Wang, Jia Yue, Wenbin Wang, Liying Qian

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INVESTIGATION OF UV/TiO2-ZnO-Co PHOTOCATALITIC DEGRADATION OF AZO DYE (REACTIVE RED 120) BY RESPONSE SURFACE METHODOLOGY by MOHSEN MANSOURI, MARJAN TANZIFI, HOSSEIN LOTFI, MOHSEN NADEMI

“…Results were in agreement with empirical values and the sensitivity analysis showed above parameters as the most efficient variables in decolorization efficiency. Analysis of variance (ANOVA) revealed highly determination coefficient value (R2 = 0.9996 and adjusted-R2 = 0.999) and satisfactory prediction second-order regression model. …”
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Sports Biomechanics Analysis: Assisting Effectiveness Evaluations for Wearable Compliant Elbow Joint Powered Exoskeleton by Huibin Qin, Kai Liu, Zefeng Zhang, Jie Zheng, Zhili Hou, Lina Li, Ruiqin Li

“…Firstly, a powered wearable elbow exoskeleton with variable stiffness is proposed. Through theoretical calculation, the power efficiency formula of exoskeleton is derived. …”
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Simplified Model Characterization and Control of an Unmanned Surface Vehicle by Aldo Lovo-Ayala, Roosvel Soto-Diaz, Carlos Andres Gutierrez-Martinez, Jose Fernando Jimenez-Vargas, Javier Jiménez-Cabas, Jose Escorcía-Gutierrez

“…Two models were built, one based on a transfer function matrix and another based on state variables, and from these models, two control strategies were developed. …”
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Near-source wastewater surveillance of SARS-CoV-2, norovirus, influenza virus and RSV across five different sites in the UK. by Jay C Bullen, Mina Mohaghegh, Fatima Tahir, Charlotte Hammer, Jacob Sims, Frederico Myers, Lucas Eisinger, Ali Reza Kasmati, Claire F Trant

“…The key findings are (1) near-source wastewater detections were linked to local events (staff sickness, enhanced cleaning, changing populations); (2) wastewater detections decreased in the order norovirus GII > norovirus GI > SARS-CoV-2 ≈ influenza A ≈ RSV A > influenza B ≈ RSV B; (3) correlation between near-source wastewater data and national surveillance data increases as a function of catchment size and viral prevalence (examples include the SARS-CoV-2 BA.4/BA.5 variant peak at a museum and wastewater tracking the winter norovirus season); (4) strong weekday periodicity in near-source wastewater SARS-CoV-2 detections, with the correlation against COVID-19 case numbers increasing when modelling variable lag times between faecal shedding onset and clinical diagnosis (R2 = 0.45 increases to 0.84-0.86); (5) a log-linear relationship between the frequency of wastewater SARS-CoV-2 detection and log(catchment size⋅viral prevalence) (R2 = 0.6914-0.9066). …”
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Sensitivity and optimization study on heat transfer enhancement of MHD hybrid nanofluid radiative transient flow past a spinning surface with quadratic Boussinesq approximation and... by Thirupathi Thumma, Surender Ontela, Rupalaksmi Dharanikota

“…The optimization process pinpoints the ideal conditions for maximizing heat transfer efficiency. From the results, it is observed that the rise in parameters of the heat source and radiation together significantly improves response function while the same trend is observed when both radiation and volume fraction rise from lower to higher values, the heat transfer rate improves notably. …”
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Integrating Drone Truthing and Functional Classification of Remote Sensing Time Series for Supervised Vegetation Mapping by Giacomo Quattrini, Simone Pesaresi, Nicole Hofmann, Adriano Mancini, Simona Casavecchia

“…This study proposes an approach to enhance the efficiency of supervised vegetation mapping in complex landscapes, integrating Multivariate Functional Principal Component Analysis (MFPCA) applied to the Sentinel-2 time series with drone-based ground truthing. …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…We used it to assess the effect of long-term consumption of total and non-fermented dairy on cognitive function. Methods We included 43,836 individuals over 55 years old with genotyping, dietary data, and cognitive function measurements from three population-based studies: CoLaus|PsyCoLaus (Switzerland), the Rotterdam Study (the Netherlands) and the Canadian Longitudinal Study on Aging (CLSA - Canada). …”
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Longitudinal optimal analytical midcourse guidance for cruise-glide integrated hypersonic vehicles by Xin Li, Guangbin Cai, Hui Xu, Jianwen Zhu, Chaoxu Mu

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Kiperin Postbiotic Supplement-Enhanced Bacterial Supernatants Promote Fibroblast Function: Implications for Regenerative Medicine by Lutfiye Karcioglu Batur, Cuneyd Yavas, Yağmur Ekenoğlu Merdan, Ashabil Aygan

“…Gene expression analyses revealed no statistically significant changes, though variable trends were observed across treatment groups. …”
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Unveiling the Impact of COVID-19 on Ovarian Function and Premature Ovarian Insufficiency: A Systematic Review by Charalampos Voros, Despoina Mavrogianni, Aspasia Minaoglou, Anthi-Maria Papahliou, Vasileios Topalis, Antonia Varthaliti, Dimitris Mathiopoulos, Panagiota Kondili, Menelaos Darlas, Agni Pantou, Sophia Sina, Antonia Athanasiou, Diamantis Athanasiou, Dimitrios Loutradis, Georgios Daskalakis

“…SARS-CoV-2 disrupts ovarian function largely through oxidative stress, inflammation, and immunological dysregulation, which are enhanced by its entrance into ovarian tissues via ACE2 receptors. …”
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Expression and functional characterization of an anti-CD22 scFv targeting B-cell malignancies by Monireh Gholizadeh, Shahriyar Abdoli, Shafieeh Mansoori, Arash Arashkia, Farhad Riazi-Rad, Amir Ali Hamidieh, Mohammad Nouri, Zahra Sharifzadeh

“…Background and purpose: Single-chain variable fragments (scFvs) offer advantages over full-length monoclonal antibodies in cancer therapy, including reduced size, lower production costs, and easier handling. …”
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Application of random survival forest for competing risks in prediction of cumulative incidence function for progression to AIDS by Omid Hamid, Mahtab Tapak, Jalal Poorolajal, Payam Amini, Leili Tapak

“…Result: The used model indicated that using antiretroviral therapy tuberculosis co-infection are two top most important variables in predicting cumulative incidence function for AIDS progression in the presence of competing risks, respectively. …”
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The exactness of the ℓ1 penalty function for a class of mathematical programs with generalized complementarity constraints by Yukuan Hu, Xin Liu

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Integrated approach for estimating climate change impacts on CO2 sink capacity of inland waterbodies using hydrodynamic modelling and GIS analysis by Hanady H. Khalil, Mohamed A. Abdrabo, Mahmoud A. Hassaan, Mohamed M. Elshemy

“…Abstract As one of their key regulatory ecosystem functions, inland lakes serve as CO2 sinks. The CO2 sink capacity of inland lakes depends on their water temperature and salinity as well as their water volume which are all highly sensitive to climate conditions. …”
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Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19 by Benjamin L Spector, Boryana Koseva, Rebecca McLennan, Dithi Banerjee, Kamani Lankachandra, Todd Bradley, Rangaraj Selvarangan, Elin Grundberg

“…We also identified hypermethylation of ELF5 binding sites suggesting downregulation of ELF5 targets in the nasal cavity as a factor in COVID-19 phenotypic variability. Conclusions This study demonstrated DNA methylation as a marker of the immune response to SARS-CoV-2 infection, with enhancer-like elements playing significant roles. …”
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Control of an autonomous wind energy conversion system based on doubly fed induction generator supplying a non-linear load by M. L’Hadj Said, M. Ali Moussa, T. Bessaad

“…Simulation results carried out on MATLAB/Simulink show that this filter allows obtaining a quasi-sinusoidal network voltage and it also has the advantage of a simple structure, a good efficiency and a great performance. This proves the feasibility and efficiency of the proposed system for different loads (linear or non-linear). …”
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Depth-dependent contributions of various vascular zones to cerebral autoregulation and functional hyperemia: An in-silico analysis. by Hadi Esfandi, Mahshad Javidan, Rozalyn M Anderson, Ramin Pashaie

“…However, temporal alterations in capillary diameter contribute moderately to cerebral autoregulation and minimally to functional hyperemia. In addition, hemodynamic analysis shows that while hemodynamics within capillaries remain relatively stable across all cortical depths throughout the entire autoregulation range, significant variability in hemodynamics can be observed within the first few branch orders of precapillary arterioles or transitional zone vessels. …”
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