Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Our findings provide the first demonstration that TXA efficiently inhibits MSC-driven plasmin generation by competitively blocking plasminogen binding to the uPA•uPAR complex at the cell plasma membrane.DiscussionWe propose that plasmin formation on MSCs may be involved in pathological processes such as endometrial hemorrhage (metrorrhagia and Post-Partum Hemorrhage), autoimmune and ischaemic diseases, as well as cancer. …”
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EEGUnity: Open-Source Tool in Facilitating Unified EEG Datasets Toward Large-Scale EEG Model by Chengxuan Qin, Rui Yang, Wenlong You, Zhige Chen, Longsheng Zhu, Mengjie Huang, Zidong Wang

“…To tackle the challenges, this paper introduces EEGUnity, an open-source tool that incorporates modules of "EEG Parser", "Correction", "Batch Processing", and "Large Language Model Boost". Leveraging the functionality of such modules, EEGUnity facilitates the efficient management of multiple EEG datasets, such as intelligent data structure inference, data cleaning, and data unification. …”
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Neutral Mode Dominates the Forced Global and Regional Surface Temperature Response in the Past and Future by Fukai Liu, Jian Lu, L. Ruby Leung

“…Abstract Using a large suite of Green's function perturbation experiments, we construct the emergent dynamical operator for surface temperature and extract the most excitable mode. …”
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Engineering students' perceptions and actual use of AI-based math tools for solving mathematical problems by Kimberly F. Garcia, Ardvin Kester S. Ong, Ma. Janice J. Gumasing, Cesar Romeo V. Delos Reyes

“…The outcome indicated that students are more inclined to utilize AI tools when they find them engaging and are convinced that they can employ them efficiently and incorporate the tools in their academic routines. …”
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Importance of ice algae versus phytoplankton in the diet of megabenthic organisms under contrasting sea ice conditions (Canadian Arctic): a dual biochemical approach (SIA and HBIs) by Thibaud Combaz, Thibaud Combaz, Ursula Witte, Thomas A. Brown, Philippe Archambault

“…Overall, organisms responded rapidly and efficiently to this pulse of fresh organic matter but trends in resource utilisation (quality and quantity) were observed based on feeding strategy. …”
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Comparing machine learning approaches for estimating soil saturated hydraulic conductivity. by Ali Akbar Moosavi, Mohammad Amin Nematollahi, Mohammad Omidifard

“…Results revealed that all NN models particularly PSO-NNs were efficient in prediction of Kfs. However, further evaluations may be recommended for other soil conditions and input variables to quantify their potential uncertainties and wider potential and versatility before they are used in other geographical locations/soil conditions.…”
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Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

“…Thus, the aim of the present research is to find the variables affecting community-based tourism in the target villages of Markazi Province. …”
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TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1 by Christina Funk, Nadja Uhlig, Zsolt Ruzsics, Florentin Baur, Matthias Peindl, Sarah Nietzer, Karina Epting, Gabriele Vacun, Gudrun Dandekar, Catherine Botteron, Christian Werno, Thomas Grunwald, Susanne M. Bailer

“…Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. …”
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Identification and leveling of factors affecting the acceptance of excellence model in Islamic Azad University by Seyedeh Somayeh Mousavi Siah Deleh, Samad Jabbari Asl, Musa Rezvani Chaman Zamin

“…The concept of institutional excellence in higher education institutions as mentioned by Kok & McDonald (2017) refers to behavior that leads to excellence in all research, teaching and social service functions through excellence in strategy and shared values, leadership, Organizational culture. …”
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Emerging Role of Mesenchymal Stromal Cell and Exosome Therapies in Treating Cognitive Impairment by Vick Key Tew, Muttiah Barathan, Fazlina Nordin, Jia Xian Law, Min Hwei Ng

“…Cognitive aging, characterized by the gradual decline in cognitive functions such as memory, attention, and problem-solving, significantly impacts daily life. …”
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Decellularized adipose-derived matrix from Superficial layers of abdominal adipose tissue exhibits superior capacity of adipogenesis compared to deep layers by Xiaomu Ma, Qiang Yue, Su Fu, Chunjun Liu, Jie Luan

“…These findings not only deepen our comprehension of the structural and functional heterogeneity of adipose tissues but also become one of the reason for the large variability between batches of DAM products, providing guidance for constructing more efficient and stable bio-scaffolds.…”
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Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
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eDNAjoint: An R package for interpreting paired or semi‐paired environmental DNA and traditional survey data in a Bayesian framework by Abigail G. Keller, Ryan P. Kelly

“…Abstract Environmental DNA (eDNA) sampling is increasingly used in surveys of species distribution as a potentially sensitive and efficient monitoring method. Yet access to modelling tools designed specifically for interpreting this new data type lags behind its ubiquity. …”
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Reducing Building Energy Performance Gap: Integrating Agent-Based Modelling and Building Performance Simulation by Chi-Li Chiang, John Calautit

“…The building energy performance gap (BEPG) remains a significant challenge, undermining the accuracy of energy simulations and complicating efforts to design energy-efficient buildings. This study addresses this issue by developing an adaptive occupant behaviour framework for office buildings, integrating agent-based modelling (ABM) with a building performance simulation (BPS) platform. …”
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Motor Imagery during Action Observation of Locomotor Tasks Improves Rehabilitation Outcome in Older Adults after Total Hip Arthroplasty by Uros Marusic, Sidney Grosprêtre, Armin Paravlic, Simon Kovač, Rado Pišot, Wolfgang Taube

“…These results demonstrate that AO + MI is efficient to improve motor-cognitive performance after hip surgery. …”
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Automated Geographic Information System Multi-Criteria Decision Tool to Assess Urban Road Suitability for Active Mobility by Bertha Santos, Sandro Ferreira, Pollyanna Lucena

“…As a result, a flexible and automated GIS-based tool was obtained to support urban space and mobility managers in the implementation of efficient measures compatible with each city’s scenario.…”
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Multimodality Data Integration in Epilepsy by Otto Muzik, Diane C. Chugani, Guangyu Zou, Jing Hua, Yi Lu, Shiyong Lu, Eishi Asano, Harry T. Chugani

“…Moreover, an effort was made to derive quantitative variables (such as the spatial proximity index, SPI) characterizing the relationship between complementing modalities on a more generic level as a prerequisite for efficient data mining strategies. …”
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Providing a Roadmap for the Adaption of Agricultural Sector to Water Scarcity Conditions (Case Study: Selected Crops of Tajan Basin, Iran) by H. Fouladi, H. Amirnejad, S. Shirzadi Laskookalayeh

“…For this reason, the void of using an efficient model that can provide all economic and environmental aspects at the same time was completely felt. …”
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Evolution and transformation of vineyard landscapes and promotion of sustainable viticulture. The case of Boukornine protected area in Tunisia by Abdelkarim Hamrita, Faouzi Haouala, Khouloud Annabi, Rania Kouki, Rania Kouki, Mokhtar Rejili, Bouthaina Al Mohandes Dridi

“…This shift has contributed to landscape homogenization and a decline in ecological functionality. Nonetheless, the vicinity of Boukornine National Park provides critical ecosystem services—such as microclimate regulation and biodiversity support—that buffer vineyards against environmental stressors.DiscussionThe study emphasizes the need for sustainable transitions in vineyard management through the adoption of organic farming practices, efficient irrigation systems, and the valorization of local terroirs. …”
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Energy‐maximising moment‐based constrained optimal control of ocean wave energy farms by Nicolás Faedo, Giordano Scarciotti, Alessandro Astolfi, John V. Ringwood

“…The authors develop a framework under which the objective function (and system variables) can be mapped to a finite‐dimensional tractable quadratic program (QP), which can be efficiently solved using state‐of‐the‐art solvers. …”
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