Molecular and immune landscape of melanoma: a risk stratification model for precision oncology by Miao Sun, Junliang Wu

“…Knockdown efficiency was confirmed by qRT-PCR. Functional assays revealed that KIR2DL4 silencing significantly reduced cell proliferation, as assessed by MTT assay, and impaired migratory capacity, as demonstrated by wound healing assay. …”
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Systematic Evaluation of Isolation Techniques and Freeze‐Thaw Effects on Plasma Extracellular Vesicle Heterogeneity and Subpopulation Profiling by Xueqi Li, Xiangyu Li, Lingjun Tong, Liqiao Hu, Yanfen Hong, Ruoyu Zhou, Zonghong Li, Ming Dong, Junjie Hou, Tao Xu, Wen Zhong

“…However, standardizing blood‐derived EV isolation remains challenging due to the heterogeneity of EV populations and variability among isolation techniques. In this study, we systematically evaluated three distinct EV isolation methods, including asymmetrical flow field‐flow fractionation (AF4), size‐exclusion chromatography (SEC) and automated centrifugal microfluidic disc system combined with functionalized membranes (Exo‐CMDS), to compare their efficiency in isolating EVs from both freshly frozen and freeze‐thawed plasma samples. …”
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Investigating the influence of soil organic carbon on pore structure within aggregates by Jingjing Liu, Yu Tian, Chiara Pasut, Mark Farrell, Shenggao Lu

“…The results revealed that the hydrogen peroxide treatment variably reduced organic carbon in soil aggregates, with Cambisol samples showing a higher removal efficiency (38.58–63.31%) compared to Ultisol samples (27.33–45.74%). …”
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ANALYTICAL SOLUTIONS OF NON-LINEAR HEAT CONDUCTION PROBLEMS by V. A. Bondarev

“…An example of calculations in the case of variable coefficients of thermal conductivity and radiative heating transfer on the boundaries is considered in the paper. …”
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Complete sequencing of the mitochondrial genome of tea plant Camellia sinensis cv. ‘Baihaozao’: multichromosomal structure, phylogenetic relationships, and adaptive evolutionary an... by Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zixu Wang, Zixu Wang, Zixu Wang, Zixu Wang, Wei Zhou, Wei Zhou, Wei Zhou, Wei Zhou, Sijie Liu, Sijie Liu, Sijie Liu, Sijie Liu, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yihui Gong, Yihui Gong, Yihui Gong, Yihui Gong

“…Additionally, 1.62% of the mitochondrial genome sequence was homologous to the chloroplast genome, carrying 26 complete functional genes, including 15 tRNA and 2 rRNA genes.DiscussionCodon usage bias may be related to mutation pressure due to the high AT content of the genome or reflect adaptive selection pressures for translational efficiency. …”
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Uncovering soil compaction: performance of electrical and electromagnetic geophysical methods by A. Carrera, A. Carrera, L. Peruzzo, M. Longo, G. Cassiani, F. Morari

“…In this context, soil compaction resulting from inappropriate agricultural practices not only affects soil ecological functions, but also decreases the water-use efficiency of plants by reducing porosity and increasing water loss through superficial runoff and enhanced evaporation.…”
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FVPNet: A Fuzzy Visual Positioning Perception Network for Small Object Segmentation in Remote Sensing Images by Yu Yan, Jindong Xu, Qianpeng Chong, Guangyi Wei, Zhixiang Wang

“…Furthermore, grayscale variability intensifies boundary uncertainty, complicating accurate segmentation. …”
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Assessing service quality and its impact on patient experience and satisfaction in prosthetics and orthotics: a SERVQUAL-based cross-sectional study by Mahmoud Alfatafta, Nizar Alsubahi, Huda Alfatafta, Amneh Alshawabka, Anthony McGarry, Alaeddin Ahmad, Evelin Derkacs, Dorottya Varga, Bálint Molics

“…Reliability significantly influenced PS (p < 0.001) but had no impact on PE (p = 0.386), while Empathy did not significantly affect PS (p = 0.311), suggesting that practical aspects such as device functionality and efficiency may be prioritized over emotional considerations in P&O care. …”
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Risk Assessment Approach of Toll Road Operator by A. Yu. Talavirya, M. B. Laskin

“…All such factors are modeled in the AnyLogic environment as random variables with a rich choice of distribution functions and their parameters.Results. …”
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Genome‐wide screening of abberant methylated drivers combined with relative risk loci in bladder cancer by Chuanjie Zhang, Kangjie Shen, Yuxiao Zheng, Feng Qi, Jun Luo

“…MethylMix package was used for identifying methylation‐driven genes and functional analysis was mainly performed based on ConsensusPathDB database. …”
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ITER NBI operational window and power availability constraints due to shine-through losses by P. Vincenzi, M. Schneider, P. Veltri, J.F. Artaud, A. Loarte, S. Nicolici, C. Poggi, A.R. Polevoi, A. Snicker

“…We then present a new heuristic formula which permits the calculation of the ST fraction and the minimum plasma density that permits ITER NBI operations as a function of global variables. This allows for establishing operational limits for Hydrogen and Deuterium NBI in Hydrogen, Deuterium, and Deuterium–Tritium plasmas. …”
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Exploring Machine Learning Models for Vault Safety in ICL Implantation: A Comparative Analysis of Regression and Classification Models by Qing Zhang, Qi Li, Zhilong Yu, Ruibo Yang, Emmanuel Eric Pazo, Yue Huang, Hui Liu, Chen Zhang, Salissou Moutari, Shaozhen Zhao

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Automated ejection fraction and risk stratification in cardiomyopathy patients with diverse LV geometry using 2D echocardiography by Ziwei Zhu, Ke Fan, Shuyuan Zhang, Tingting Hu, Jingyi Li, Ze Zhao, Ye Jin, Shuyang Zhang

“…Abstract Cardiomyopathy often alters left ventricular geometry (LVG), impairing cardiac function. We developed a deep learning (DL) model to estimate left ventricular ejection fraction (LVEF) from echocardiographic images while accounting for LVG variability and assessed prognostic factors across LVG subtypes. …”
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Differentiation and correlation of regional uptake heterogeneity with cardiac dysfunction in biopsy-proven transthyretin amyloid cardiomyopathy using quantitative single-photon emi... by Masakazu Tsujimoto, Hideki Kawai, Shingo Tanahashi, Masayoshi Sarai, Yasuki Asada, Hideo Izawa

“…Polar maps were analyzed to assess local SUV distribution in patients with ATTR-CM. The coefficient of variation (COV) of myocardial uptake, difference score between the septum and lateral wall (%DS), base-to-apex variability, and total cardiac SUV were calculated and compared with echocardiographic parameters. …”
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GAN-based image prediction of maize growth across varieties and developmental stages by Xinyi Wang, Shilong Liu, Zhihao Wang, Zedong Geng, Weikun Li, Chengxiu Wu, Yingjie Xiao, Wanneng Yang, Lingfeng Duan

“…Results This article proposed a visualized growth prediction method based on an improved Pix2PixHD network, incorporating spatial attention mechanisms, an improved loss function, and a modified dropout strategy to enhance prediction accuracy and visual fidelity. …”
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Correlation between Stressful Life Events and Suicidal Ideation among Patients with Schizophrenia in Remission Stage: A Cross-sectional Study by Ashok Silamban, Kailash Sureshkumar, Aravindh Manogaran, Shabeeba Z Kailash

“…Introduction: Patients with schizophrenia often exhibit impaired executive brain function, which disrupts their daily activities. Relapse in schizophrenia has been linked to stressful life events. …”
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Spatial Analysis of the Relationship between Ecological Factors and Housing Prices in Tehran by Atefeh Kolyaei, Tahir Prizadi, Habibollah Fasihi

“…Among the independent variables, the average annual temperature, distance from river valleys, distance from fault lines, and green coverage showed the highest correlation coefficients; however, these relationships were negative, indicating an inverse correlation. …”
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Human saliva exerts strong type-dependent effects on adenovirus infectivity by Erwan Sallard, Wenli Zhang, Nikita Chilakamarri, Setareh Farzanehkari, Setareh Farzanehkari, Inga Marte Charlott Seuthe, Anja Ehrhardt, Malik Aydin, Malik Aydin

“…All human Ads used were replication-competent and expressed a GLN cassette containing a green-fluorescent protein, nano-luciferase, and neomycin resistance. Loss-of-function experiments were conducted by immunoprecipitation or enzymatic digestion of specific saliva components to decipher related mechanisms.ResultsTemporal and inter-individual variability in saliva samples were observed, validating the use of a saliva pool to represent the population. …”
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AngleCam: Predicting the temporal variation of leaf angle distributions from image series with deep learning by Teja Kattenborn, Ronny Richter, Claudia Guimarães‐Steinicke, Hannes Feilhauer, Christian Wirth

“…The plausibility of the predicted leaf angle time series was underlined by its close relationship with environmental variables related to transpiration. The evaluations confirm that AngleCam is a robust and efficient method to track leaf angles under field conditions. …”
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Supply chain management and optimization in transportation logistics by Saoussen Krichen

“…SCM can also be seen as the process of optimizing a set of decisions that generate cost-effective solutions which provide efficient plans for acting on numerous levels while considering all decision-making standpoints. …”
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