Development of smart samplers and their comparison to dried serum spots for the analysis of growth hormone releasing hormone analogs using LCHRMS/MS by Christina Johannsen, Anna Kha Tu Nguyen, Sasha Shabani, Inger Oulie, Siri Dørum, Yvette Dehnes, Leon Reubsaet, Trine Grønhaug Halvorsen

“…DSS and smart samplers were compared for extraction efficiency, precision, and detection capabilities. Various extraction approaches were evaluated to optimize analyte recovery followed by a blind sample study to assess detection capability at unknown concentrations. …”
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Optimized Dual-Battery System with Intelligent Auto-Switching for Reliable Soil Nutrient Monitoring in Remote IoT Applications by Doan Perdana, Pascal Lorenz, Bagus Aditya

“…Implementing the DLB–PAO algorithm elevates the average reliability to 91.7% over 120 h, whereas the DLB–GA algorithm achieves near-perfect reliability (99.9%) for over 170 h, exhibiting minimal variability (standard deviation: 0.9%). The integration of intelligent auto-switching mechanisms and metaheuristic optimisation algorithms demonstrates a marked enhancement in both reliability and energy efficiency for soil nutrient monitoring systems. …”
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Assessment of the Potential of Decentralized Dinance (DeFi) as an Alternative to Traditional Financial Services in the Context of the Development of the Digital Economy and Web3 by Manoilenko Oleksandr V., Kuznetsova Svitlana O., Pysakovskyi Anton O.

“…An analysis of the main characteristics of DeFi protocols, their functional capabilities, and differences from centralized financial institutions has been conducted. …”
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Research on Design and Energy-Saving Performance of Gate Rudder by Chunhui Wang, Qian Gao, Lin Li, Feng Gao, Zhiyuan Wang, Chao Wang

“…The GRS was first fully implemented on a container ship in Japan, demonstrating improved propulsion efficiency, fuel savings, and excellent performance in maneuvering, noise, and vibration reduction. …”
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Comparative Study on the Treatment Effect of Stretching and High-frequency Diathermy in Subjects With Gastrocnemius Tightness by Beom-Seop Kim, Yixin Wang, Ye-Jin Kim, Min-Young Kim, Hye-Seon Jeon

“…Background: Ankle flexibility is important for maintaining proper biomechanical function. Static stretching is used to improve flexibility with minimal risk; however, its effects are often temporary. …”

Cultivares de trigo submetidas a déficit hídrico no início do florescimento, em casa de vegetação Wheat cultivars submitted to water deficit at the beginning of flowering in greenh... by Diego dos Santos, Vandeir F. Guimarães, Jeferson Klein, Samuel L. Fioreze, Eurides K. Macedo Júnior

“…Reduction was found in the gravimetric soil moisture, in the relative levels of water and in all biometric variables, in function of the water deficit. The grain production showed difference only among the water regimes, in which the cultivar CD 111 is more efficient in the maintenance of the productive potential in conditions of water deficit, through the quick recovery in the relative content of water in leaves.…”
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Correlation of magnetic resonance imaging parameters with montreal cognitive assessment-Indonesian (MOCA-INA) score in dementia patients at Prof. Dr. IGNG Ngoerah General Hospital,... by Made Widhi Asih, Elysanti Dwi Martadiani, I Wayan Gede Artawan Eka Putra, Felicia Nike, Putri Ayu Ratnasari, Nugra Arenz Raturandang, Jessieca Liusen, Anak Agung Parama Swari Khrisna, Luh Dindi Ayu Surya Kanti, Adsel Kartadinata

“…Correlation between variables was evaluated based on the correlation coefficient, which indicates the direction and strength of the correlation. …”
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Fabrication of Wood-Derived Carbon Aerogel/Mg(OH)₂ Bio-Composite and Its High Performance for Adsorption and Separation of Cadmium Ions by Ran An, Jinyue Liu, Haomiao Ma, Yuqing Yan, Yuanru Guo, Qingjiang Pan, Shujun Li

“…The resulting wood-derived carbon aerogels (WCA) were functionalized with Mg(OH)₂ to boost their environmental remediation potential. …”
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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A Multi-Task Based Deep Learning Framework With Landmark Detection for MRI Couinaud Segmentation by Dong Miao, Ying Zhao, Xue Ren, Meng Dou, Yu Yao, Yiran Xu, Yingchao Cui, Ailian Liu

“…To achieve precise Couinaud liver segmentation in preoperative planning for hepatic surgery, accommodating the complex anatomy and significant variations, optimizing surgical approaches, reducing postoperative complications, and preserving liver function.This research presents a novel approach to automating liver segmentation by identifying seven key anatomical landmarks using portal venous phase images from contrast-enhanced magnetic resonance imaging (CE-MRI). …”
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Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review by Mehvish Aqil, Saif Ur Rahman, Muhammad Zeeshan Aslam, Mostafa Ahmed Abdellah Ahmed, Ammar Ahmed, Sidra Javaid, Ehsan Ul Haq

“…The MMP-7 was consistently elevated in 73.3% (n=11) of the studies and correlated with disease severity, lung function decline, and progression. In 46.7% (7) of studies, MMP-9 was associated with imaging severity and functional impairments, and in 26.7% (4) of studies, MMP-7 was found as the strongest biomarker, and the correlation coefficient calculated was from (r = 0.65 to 0.80), for MMP-9 it was (r = 0.4 to 0.6) and for MMP-1 (r = 0.3 to 0.45). …”
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Data-driven diabetes mellitus prediction and management: a comparative evaluation of decision tree classifier and artificial neural network models along with statistical analysis by Idris Zubairu Sadiq, Babangida Sanusi Katsayal, Bashiru Ibrahim, Maryam Ibrahim, Hassan Aliyu Hassan, Umar Muhammad Ghali, Abdullahi Garba Usman, Abubakar Usman, Sani Isah Abba

“…Principal Component analysis further highlighted five clusters of health-related variables, identifying age-related metabolic indicators (AGE, HbA1c, BMI), kidney function markers (creatinine (Cr), Urea), cardiovascular lipid profiles (Cholesterol, LDL), lipid transport (VLDL), and protective cardiovascular indicator (HDL). …”
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Quantitative analysis of ocular deviation under eye occlusion: a descriptive study using the ORTe EYENAC eye-tracking system by Shunya Tatara, Yuna Magara, Touko Sasaki, Fumiatsu Maeda, Noriaki Murata, Kazuhiro Itagaki, Tomoya Handa, Haruo Toda

“…Data were fitted to a logistic function to estimate ocular deviations, deviation speed, and stabilization time. …”
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Application of multi-objective neural network algorithm in industrial polymerization reactors for reducing energy cost and maximising productivity by Fakhrony Sholahudin Rohman, Sharifah Rafidah Wan Alwi, Dinie Muhammad, Ashraf Azmi, Zainuddin Abd Manan, Jeng Shiun Lim, Hong An Er, Siti Nor Azreen Ahmad Termizi

“…Optimization on an industrial scale is a complex task that involves fine-tuning the performance of large-scale systems and applications to make them more efficient and effective. This process can be challenging due to the increasing volume of work, growing system complexity, and the need to maintain optimal performance. …”
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Impact of pulmonary rehabilitation in sleep in COPD patients measured by actigraphy. by Suman B Thapamagar, Kathleen Ellstrom, James D Anholm, Ramiz A Fargo, Nagamani Dandamudi

“…Paired comparisons (t-test or Wilcoxon-signed-rank test) were performed before and after PR data on all variables.<h4>Methods</h4>This retrospective study of COPD patients undergoing PR utilized actigraphy watch recordings before and after 8-weeks of PR to assess changes in sleep variables including total time in bed (TBT), total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), wakefulness after sleep onset (WASO) and total nocturnal awakenings. …”
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The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass by Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément

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Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features by Ameya Harmalkar, Roshan Rao, Yuxuan Richard Xie, Jonas Honer, Wibke Deisting, Jonas Anlahr, Anja Hoenig, Julia Czwikla, Eva Sienz-Widmann, Doris Rau, Austin J. Rice, Timothy P. Riley, Danqing Li, Hannah B. Catterall, Christine E. Tinberg, Jeffrey J. Gray, Kathy Y. Wei

“…In this work, we show two machine learning approaches – one with pre-trained language models (PTLM) capturing functional effects of sequence variation, and second, a supervised convolutional neural network (CNN) trained with Rosetta energetic features – to better classify thermostable scFv variants from sequence. …”
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Novel variant alters splicing of TGFB2 in family with features of Loeys-Dietz syndrome by Emily R. Gordon, Stephanie A. Felker, Stephanie A. Felker, Tanner F. Coleman, Tanner F. Coleman, Nadiya Sosonkina, Jada Pugh, Jada Pugh, Meagan E. Cochran, Meagan E. Cochran, Anna C. E. Hurst, Sara J. Cooper

“…Molecular validation of the splicing products suggests that the TGFB2 variants tested impact splicing by reducing efficiency of the canonical acceptor in favor of an alternate acceptor within the exon. …”
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FMRI insights into the neural alterations and clinical correlates in multiple sclerosis: A comprehensive overview of systematic reviews and meta-analyses by Sama Rahnemayan, Arezoo Fathalizadeh, Mehdi Behroozi, Mahnaz Talebi, Amirreza Naseri, Elham Mehdizadehfar

“…Graph theory metrics identified disrupted global efficiency and clustering in functional networks, linked to gray matter atrophy. …”
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Multi-objective optimization of an open-pit mining system to determine safety buffer using the modified NBI method and the meta-model approach by Tahereh Khajvandsany, Hossein Amoozad Khalili, Ramezan Rezaeyan, Kourosh Nemati

“…The central composite design (CCD) method was used to develop the design of experiments (DOE) for the design variables. Results: according to obtained findings, the considered design variables were the number of trucks of 120 tons, 240 tons, 35 tons, and 100 tons. …”
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