Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza by Zhaoyuan Gong, Qianzi Che, Mingzhi Hu, Tian Song, Lin Chen, Haili Zhang, Ning Liang, Huizhen Li, Guozhen Zhao, Lijiao Yan, Xuefei Zhang, Bin Liu, Jing Guo, Nannan Shi

“…The high risk of viral variability, drug resistance, and drug development leads to a scarcity of therapeutic drugs. …”
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Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer by Lei Shi, Lei Shi, Lei Shi, Xuyang Zhong, Jiafeng Liu, Yong Ying, Zibing Liao, Jin Liu, Liwen Zhao, Jianing Zhong, Jianing Zhong, Xiangtai Zeng, Xiangtai Zeng

“…We systematically dissect the multifaceted regulatory circuits governing lactate metabolism by integrating three pivotal dimensions: (i) canonical signaling cascades; (ii) tumor-microenvironmental variables, most notably hypoxia and acidosis; and (iii) the emerging epigenetic paradigm of lactylation, which dynamically reprograms the catalytic efficiency of rate-limiting enzymes and reshapes the transcriptional landscape of metabolic genes, thereby precisely coordinating lactate homeostasis. …”
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Deep Reinforcement Learning With Dueling DQN for Partial Computation Offloading and Resource Allocation in Mobile Edge Computing by Ehzaz Mustafa, Junaid Shuja, Faisal Rehman, Abdallah Namoun, Mazhar Ali, Abdullah Alourani

“…The Dueling DQN alleviates the complexity of simultaneous offloading and resource allocation decisions, with each branch independently controlling a subset of the decision variables to scale efficiently with an increasing number of IoT devices, thereby avoiding the combinatorial explosion of potential actions. …”
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Comparative Evaluation of Vibratory Physiotherapy Methods in the Early Period after Cardiac Surgery by А. А. Eremenko, T. P. Zyulyaeva, D. V., Ryabova, А. P. Аlferova

“…Mechanical respiratory therapy procedures led to significant improvement in gas exchange variables, as evidenced by an increase in SpO2 in Groups 1 and 2 (p = 0.000009 and 0.000001, respectively) and a decrease in the proportion of patients with impaired oxygenating lung function (SpO2 below 92%) by 11 and 12 times, respectively (p < 0.01). …”
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Efectos de los factores de edificabilidad sobre la productividad laboral de moldajes de vigas en fundaciones The effects of buildability factors on formwork labor productivity of g... by Abdulaziz M Jarkas

“…Therefore, the objective of this research is to investigate and quantify the effects and relative influence of the following buildability factors on formwork labor efficiency of this activity: (a) variability of beam sizes; (b) beam sizes; and (c) number of joints formed at beams intersections. …”
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不同种群元宝枫种仁含油率及脂肪酸组成分析与评价Analysis and evaluation of oil content in seed kernel and fatty acid composition of Acer truncatum from different populations... by 韩旻昊1，2，燕丽萍1，王因花1，任飞1，梁燕1，仲伟国1，孙超1，吴德军1 HAN Minhao1,2, YAN Liping1, WANG Yinhua1, REN Fei1, LIANG Yan1, ZHONG Weiguo1, SUN Chao1, WU Dejun1

“…The average coefficients of variation of oil content in seed kernel and various main fatty acid from Haiyang, Shandong(12.59%), Tai′an, Shandong(11.22%) and Jinan, Shandong(10.36%) were higher. …”
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The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review by Stanisław Dudek, Weronika Koziak, Aleksandra Bętkowska, Agata Kornacka, Kamila Szostak, Rafał Tomaka, Michalina Makieła, Wojciech Dudek, Anna Byra

“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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Adaptive Model Predictive Control for 4WD-4WS Mobile Robot: A Multivariate Gaussian Mixture Model-Ant Colony Optimization for Robust Trajectory Tracking and Obstacle Avoidance by Hayat Ait Dahmad, Hassan Ayad, Alfonso García Cerezo, Hajar Mousannif

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Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Interestingly, some of the production- and health-related variables investigated showed significant improvement even when compared with control chickens. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery by Justin E. Kung, Chase Gauthier, Yianni Bakaes, Michael Spitnale, Richard A. Bidwell, David G. Edelman, Heidi C. Ventresca, J. Benjamin Jackson, Shari Cui, Gregory Grabowski

“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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SwinDAF3D: Pyramid Swin Transformers with Deep Attentive Features for Automated Finger Joint Segmentation in 3D Ultrasound Images for Rheumatoid Arthritis Assessment by Jianwei Qiu, Grigorios M. Karageorgos, Xiaorui Peng, Soumya Ghose, Zhaoyuan Yang, Aaron Dentinger, Zhanpeng Xu, Janggun Jo, Siddarth Ragupathi, Guan Xu, Nada Abdulaziz, Girish Gandikota, Xueding Wang, David Mills

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease that can cause severe joint damage and functional impairment. Ultrasound imaging has shown promise in providing real-time assessment of synovium inflammation associated with the early stages of RA. …”
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Protein expression profiling identifies a prognostic model for ovarian cancer by Luyang Xiong, Jiahong Tan, Yuchen Feng, Daoqi Wang, Xudong Liu, Yun Feng, Shusheng Li

“…The prognostic effect and the biological function of the model were evaluated using co-expression analysis and enrichment analysis. …”
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‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’ by Natale Massimino Ucin, Manassé Nimpagaritse, Shital Mahindra Maru, Mulatedzi Makhado, Shiferaw Mitiku Tebeka

“…Abstract Background of the study Along with developments in the clinical domain, medical equipment is becoming more sophisticated, and it needs to function at peak efficiency. In this case, hospitals should priorities the prompt and effective maintenance of life-saving equipment. …”
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Effect of Central Motor and Neuromuscular Impairments on Front Crawl Body Roll Characteristics of Para Swimmers by Yu-Hsien Lee, Dawn Nicola O’Dowd, Luke Hogarth, Brendan Burkett, Carl Payton

“…CMNI swimmers were divided into three upper-limb [mild (n = 9), moderate (n = 9), severe (n = 9)] and three lower-limb function subgroups [bilateral (n = 2), unilateral (n = 6), without kick (n = 19)] based on their Froude efficiency (a measure of how effectively upper limbs contribute to propulsion) and the number of lower limbs actively kicking during trials, respectively. …”
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Hemodynamic homeostasis disequilibrium in critical illness by Jie Wang, Xiaoting Wang, Dawei Liu, Hui Lian, Guangjian Wang, Zewen Tong, Qingyu Deng, Qirui Guo, Qian Zhang, Yangong Chao, Wanhong Yin

“…Such balance is essential for sustaining cellular metabolism and maintaining the function of vital organs throughout embryonic development and the human lifespan. …”
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Identification of Factors Affecting Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…Risk management is now an important part of project management and has a specific function for improving the efficiency of implementing the project, saving prices, and improving the profitability of projects. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Actigraphy was used to evaluate sleep and circadian rhythm, while HRV was monitored for 24 hours to assess autonomic nerve function. Nonparametric indicators were calculated to quantify the active-rest patterns, including interdaily stability, intradaily variability, the most active 10 consecutive hours (M10), the least active 5 consecutive hours (L5), the relative amplitude, and the actigraphic dichotomy index. …”
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Framework for extracting multi-objective operation rules for cascade reservoirs based on causal features and physical mechanisms by Donglin Gu, Baowei Yan, Jianbo Chang, Yixuan Zou, Dongxu Yang, Mingbo Sun, Xiaoyu Diao

“…To reduce high dimensionality, Convergent Cross Mapping (CCM) quantifies causal relationships between features and decision variables. Moreover, embedding physical constraints into the model’s loss function further enhances interpretability. …”
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The Effectiveness of Using the Reggio Emilia Approach on the Experimental Science Lesson for Third-Grade Elementary Students by Batool Sabzeh, Farangis Ghalavand, Seyedamir Ghasemtabar

“…Results of the normality test for the research variables (level 1, 2, and 3 science learning) in third-grade students indicated that all variables, both pre-test and post-test, met the assumption of normality, with significance levels greater than 0.05. …”
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