MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…IntroductionThe role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. …”
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Adaptive Stochastic Approach for Evaluating Service Level Using a (SIM-ESL) Module Developed for Optimizing Product Availability and Order Accuracy by Aufy Samah A., Jabbar Rasha, Shiaa Waad Q.

“…It is structured with two models are: Evaluation Dynamic Maximum Economic Order Quantity (EDEOQ) model developed Artificial Neural Network (ANN) to evaluate the optimum inventory level of finished goods as a function of product varied demand and lead time. The second one, Variability Between-Among Dynamic Economic Order Quantity (VB-ADEOQ) is modeled a fuzzy logic to estimate the performance measures (AOP and AOO) that make sure the required order is being processed and delivered on time. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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Optimal control for high-precision repeat ground-track orbits via convex optimization by Yanchao HE, Lei ZHANG, Yijun YANG, Qian CHEN

“…The results show that the design approach enables the realization of high-precision RGT orbit designs and that the orbit control strategy is efficient.…”
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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…Neuroimaging data, with their rich structural and functional information, provide a fertile ground for biomarker discovery. …”
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Effect of short-term dietary intervention on fecal serotonin, gut microbiome-derived tryptophanase, and energy absorption in a randomized crossover trial: an exploratory analysis by Eiichi Yoshimura, Yuka Hamada, Yoichi Hatamoto, Takashi Nakagata, Hinako Nanri, Yui Nakayama, Chiharu Iwasaka, Takanori Hayashi, Ippei Suzuki, Takafumi Ando, Kazuko Ishikawa-Takata, Shigeho Tanaka, Rei Ono, Michihiro Araki, Hitoshi Kawashima, Yi-An Chen, Jonguk Park, Koji Hosomi, Kenji Mizuguchi, Jun Kunisawa, Motohiko Miyachi

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The agricultural plastic paradox: Feeding more, harming more? by Kai Wang, Xuejun Liu, David R. Chadwick, Changrong Yan, Michaela Reay, Tida Ge, Fan Ding, Jingkuan Wang, Ruimin Qi, Mouliang Xiao, Rui Jiang, Yanling Chen, Ji Ma, Charlotte Lloyd, Richard P. Evershed, Yongming Luo, Yongguan Zhu, Fusuo Zhang, Davey L. Jones

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Randomized single-dose crossover comparative bioavailability study of two novel oral cannabidiol (CBD) formulations in healthy volunteers under fed conditions, compared to a standa... by Mehmet Nevzat Pisak, Edibe Bereket, Aydin Erenmemisoglu

“…The time to peak concentration (tmax) was shortest for the liquid (median ~ 1.0 h), followed by the capsule (2.0 h), and longest for the reference (6.0 h). Inter-individual variability in C_max and AUC was substantially lower for both novel formulations (coefficients of variation ~ 27–44%) than for the reference (> 90%). …”
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Imbalanced Power Spectral Generation for Respiratory Rate and Uncertainty Estimations Based on Photoplethysmography Signal by Soojeong Lee, Mugahed A. Al-antari, Gyanendra Prasad Joshi, Yeong Hyeon Gu

“…Thus, accurate estimation of RRs for cardiopulmonary function is essential for home health monitoring systems. …”
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Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza by Zhaoyuan Gong, Qianzi Che, Mingzhi Hu, Tian Song, Lin Chen, Haili Zhang, Ning Liang, Huizhen Li, Guozhen Zhao, Lijiao Yan, Xuefei Zhang, Bin Liu, Jing Guo, Nannan Shi

“…The high risk of viral variability, drug resistance, and drug development leads to a scarcity of therapeutic drugs. …”
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Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer by Lei Shi, Lei Shi, Lei Shi, Xuyang Zhong, Jiafeng Liu, Yong Ying, Zibing Liao, Jin Liu, Liwen Zhao, Jianing Zhong, Jianing Zhong, Xiangtai Zeng, Xiangtai Zeng

“…We systematically dissect the multifaceted regulatory circuits governing lactate metabolism by integrating three pivotal dimensions: (i) canonical signaling cascades; (ii) tumor-microenvironmental variables, most notably hypoxia and acidosis; and (iii) the emerging epigenetic paradigm of lactylation, which dynamically reprograms the catalytic efficiency of rate-limiting enzymes and reshapes the transcriptional landscape of metabolic genes, thereby precisely coordinating lactate homeostasis. …”
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Deep Reinforcement Learning With Dueling DQN for Partial Computation Offloading and Resource Allocation in Mobile Edge Computing by Ehzaz Mustafa, Junaid Shuja, Faisal Rehman, Abdallah Namoun, Mazhar Ali, Abdullah Alourani

“…The Dueling DQN alleviates the complexity of simultaneous offloading and resource allocation decisions, with each branch independently controlling a subset of the decision variables to scale efficiently with an increasing number of IoT devices, thereby avoiding the combinatorial explosion of potential actions. …”
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Comparative Evaluation of Vibratory Physiotherapy Methods in the Early Period after Cardiac Surgery by А. А. Eremenko, T. P. Zyulyaeva, D. V., Ryabova, А. P. Аlferova

“…Mechanical respiratory therapy procedures led to significant improvement in gas exchange variables, as evidenced by an increase in SpO2 in Groups 1 and 2 (p = 0.000009 and 0.000001, respectively) and a decrease in the proportion of patients with impaired oxygenating lung function (SpO2 below 92%) by 11 and 12 times, respectively (p < 0.01). …”
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Efectos de los factores de edificabilidad sobre la productividad laboral de moldajes de vigas en fundaciones The effects of buildability factors on formwork labor productivity of g... by Abdulaziz M Jarkas

“…Therefore, the objective of this research is to investigate and quantify the effects and relative influence of the following buildability factors on formwork labor efficiency of this activity: (a) variability of beam sizes; (b) beam sizes; and (c) number of joints formed at beams intersections. …”
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Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms by Hamed Naderi, Mohammad Ali Rastegar Sorkhe, Bakhtiar Ostadi, Mehrdad Kargari

“…Under the BIA, an alpha coefficient (α) of 15% is applied, whereas in the SA, each business line has a specific beta coefficient (β) ranging between 12% and 18%. …”
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不同种群元宝枫种仁含油率及脂肪酸组成分析与评价Analysis and evaluation of oil content in seed kernel and fatty acid composition of Acer truncatum from different populations... by 韩旻昊1，2，燕丽萍1，王因花1，任飞1，梁燕1，仲伟国1，孙超1，吴德军1 HAN Minhao1,2, YAN Liping1, WANG Yinhua1, REN Fei1, LIANG Yan1, ZHONG Weiguo1, SUN Chao1, WU Dejun1

“…The average coefficients of variation of oil content in seed kernel and various main fatty acid from Haiyang, Shandong(12.59%), Tai′an, Shandong(11.22%) and Jinan, Shandong(10.36%) were higher. …”
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The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review by Stanisław Dudek, Weronika Koziak, Aleksandra Bętkowska, Agata Kornacka, Kamila Szostak, Rafał Tomaka, Michalina Makieła, Wojciech Dudek, Anna Byra

“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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Adaptive Model Predictive Control for 4WD-4WS Mobile Robot: A Multivariate Gaussian Mixture Model-Ant Colony Optimization for Robust Trajectory Tracking and Obstacle Avoidance by Hayat Ait Dahmad, Hassan Ayad, Alfonso García Cerezo, Hajar Mousannif

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Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Interestingly, some of the production- and health-related variables investigated showed significant improvement even when compared with control chickens. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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