Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
Get full text

Analysis of value-based healthcare (VBHC) framework by incremental cost-effectiveness of surgical and therapeutic interventions: a retrospective study at tertiary private health gr... by Mona Khamis, Zainab Almoosa, Marie Santos, Engineer Diaa Kamal, Suhail Yaghmor, Muhammad Daniyal, Abbas Al Mutair

“…Additionally, ICER values were positively associated with better functional outcomes in MS and stroke patients, with mobility (b = 1.027, p = 0.003) and activity (b = 1.768, p < 0.001). …”
Get full text

A Low-Complexity Direction-of-Arrival Estimation Algorithm for Noncircular Signals via Subspace Rotation Technique by Wei Wang, Ming Zhang, Bobin Yao, Tongxing Zheng, Xiaojiao Fan

“…Then, utilizing the separation of variables and the orthogonality between the reduced-dimension noise subspace and the space spanned by the columns of the extended manifold matrix, a new one-dimensional spectral search function is derived to estimate DoAs. …”
Get full text

A New Ground-Motion Prediction Model for Shallow Crustal Earthquakes in Türkiye by Ulubey Çeken, Fadime Sertçelik, Abdullah İçen

“…Additionally, a heteroscedastic model was created for aleatory variability as a function of <i>M_W</i>. The closest distance to the surface projection of the fault plane (<i>R_JB</i>) is between 0 and 350 km. …”
Get full text

Elucidating Genotypic Variation in Quinoa via Multidimensional Agronomic, Physiological, and Biochemical Assessments by Samreen Nazeer, Muhammad Zubair Akram

“…The results revealed that significant variation was observed across all measured parameters, highlighting the diverse adaptive strategies and functional capacities among the tested genotypes. More specifically, genotypes Q4, Q11, Q15, and Q126 demonstrated superior agronomic potential and canopy-level physiological efficiencies, including high biomass accumulation, low infrared canopy temperatures and sustained NDVI values. …”
Get full text

EEGUnity: Open-Source Tool in Facilitating Unified EEG Datasets Toward Large-Scale EEG Model by Chengxuan Qin, Rui Yang, Wenlong You, Zhige Chen, Longsheng Zhu, Mengjie Huang, Zidong Wang

“…To tackle the challenges, this paper introduces EEGUnity, an open-source tool that incorporates modules of "EEG Parser", "Correction", "Batch Processing", and "Large Language Model Boost". Leveraging the functionality of such modules, EEGUnity facilitates the efficient management of multiple EEG datasets, such as intelligent data structure inference, data cleaning, and data unification. …”
Get full text

Assessment of heavy metal exposure risk to aquatic birds in the key wetland habitats of the Yellow River (China), using an integrated model by Jian Ding, Ni Wang, Yaqiao Lian, Qian Li, Xinran Li, Fei Yu

“…Heavy metal pollution poses a growing threat to wetland ecosystems, impacting their structure and function. Chenqiao Wetland and Qinglong Lake (Henan, China), key bird habitats in the middle and lower reaches of the Yellow River, were analyzed for heavy metal contamination. …”
Get full text

Climate Change Risk, Performance, and Value Added in Agricultural Sector by Ramin Amani, Zanko Ghorbani, Zana Mozaffari

“…Results and Discussion The results of this research show that both climate change performance index variables and climate change risk have a positive and significant effect on the added value of the agricultural sector in all three functional groups and all deciles. …”
Get full text

TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1 by Christina Funk, Nadja Uhlig, Zsolt Ruzsics, Florentin Baur, Matthias Peindl, Sarah Nietzer, Karina Epting, Gabriele Vacun, Gudrun Dandekar, Catherine Botteron, Christian Werno, Thomas Grunwald, Susanne M. Bailer

“…Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. …”
Get full text

Synergistic co-metabolism enhancing the crude oil degradation by Acinetobacter oleivorans DR1 and its metabolic potential by Lairenjam Paikhomba Singha, Renuka Kumari, Keisam Malabika Singha, Piyush Pandey, Pratyoosh Shukla

“…ABSTRACT Bacterial degradation of hydrocarbons during co-metabolism with glucose often resulted in variable degradation efficiency. This study explored the mechanistic understanding of the metabolic response during co-metabolism in Acinetobacter oleivorans DR1 using a metabolomics approach. …”
Get full text

Solving 0-1 Knapsack and Bin Packing Problem Using Logical Social Group Optimization by Rhiddhi Prasad Das, Junali Jasmine Jena, Suresh Chandra Satapathy, Naeem M. S. Hannoon

“…This prominent research gap has been addressed in this paper by introducing Logical Social Group Optimization (LSGO), a logic-based binarized variant of Social Group Optimization (SGO) that leverages Boolean logic for improved efficiency. In LSGO, after the binarization by replacing the arithmetic operators with logical operators, one of the variables gets cancelled out. …”
Get full text

Integration of indigenous and formal knowledge in the assessment of soil quality performance assessment using multiple factor analysis in Alborz central mountains by Niloufar Izadi, Fateme Aghamir

“…The current study uses Multiple Factor Analysis (MFA) to propose efficiency indicators based on the weighting of familiar, organizational, or productive variables in groups evaluating indigenous, scientific, and data variability. …”
Get full text

Multiobjective optimization of suspension bridges via coupled modeling and dual population multiobjective particle swarm optimization by Peiling Yang, Jianhua Deng, Anli Wang

“…The Lasso function is used for elastic net regression analysis to evaluate the impact of design variables on the objective functions. …”
Get full text

Neutral Mode Dominates the Forced Global and Regional Surface Temperature Response in the Past and Future by Fukai Liu, Jian Lu, L. Ruby Leung

“…Abstract Using a large suite of Green's function perturbation experiments, we construct the emergent dynamical operator for surface temperature and extract the most excitable mode. …”
Get full text

Effects of bedroom environment on average heart rate during sleep in temperate regions: Winter conditions in healthy males in their twenties with average BMI by Noriaki Oota, Yasuki Yamauchi, Gota Iwase, Masaru Abuku, Yasuhiro Hiraguri

“…Additionally, it has been suggested that as the average heart rate decreases, SDNN increases, indicating favorable autonomic function. This study aimed to identify the environmental factors that most significantly affect the day-to-day variability of average heart rate during sleep (SHR) in winter. …”
Get full text

Predictive factors of patient length of stay with multiloculated pleural effusion after medical thoracoscopy: single-center retrospective cohort study by Wiwien Heru Wiyono, Mohamad Fahmi Alatas, Andika Chandra Putra, Erlina Burhan, Amirah Nisrina, Elvan Wiyarta, Gita Fajri Gustya, Muhammad Ilham Dhiya Rakasiwi, Adlina Briliani

“…This study aimed to identify factors influencing the length of stay (LoS) after rigid medical thoracoscopy for loculated PE and assess clinical outcomes, including improvements in lung function. Method This was a retrospective cohort study conducted at St. …”
Get full text

Protocol refinement and inter- and intra-rater reliability assessment of ultrasound-based measurements of hamstring architecture, and echo intensity, and intra-rater reliability of... by Maria Belinda Cristina C. Fidel, Jan Tyrone Cabrera, Christine Grace V. Ogerio, Johann Querijero, Helen A. Banwell, Consuelo B. Gonzalez-Suarez

“…Inter-rater reliability ranged from moderate to excellent across all variables. Shear wave elastography showed moderate to excellent intra-rater reliability, with higher consistency during contraction than rest. …”
Get full text

Emerging Role of Mesenchymal Stromal Cell and Exosome Therapies in Treating Cognitive Impairment by Vick Key Tew, Muttiah Barathan, Fazlina Nordin, Jia Xian Law, Min Hwei Ng

“…Cognitive aging, characterized by the gradual decline in cognitive functions such as memory, attention, and problem-solving, significantly impacts daily life. …”
Get full text

Office-in-the-Loop: an investigation into Agentic AI for advanced building HVAC control systems by Tomoya Sawada, Masahiro Mizuno, Takaomi Hasegawa, Keiichi Yokoyama, Mayuka Kono

“…Regression analysis confirmed the robustness of our approach against confounding variables like outdoor conditions and occupancy levels. …”
Get full text

Decellularized adipose-derived matrix from Superficial layers of abdominal adipose tissue exhibits superior capacity of adipogenesis compared to deep layers by Xiaomu Ma, Qiang Yue, Su Fu, Chunjun Liu, Jie Luan

“…These findings not only deepen our comprehension of the structural and functional heterogeneity of adipose tissues but also become one of the reason for the large variability between batches of DAM products, providing guidance for constructing more efficient and stable bio-scaffolds.…”
Get full text