Applying evidence-based cross-disciplinary concepts helps to explain the heterogeneity in pain, function, and biological measures in individuals with knee pain with/at risk of oste... by Angela M. Mickle, Jared J. Tanner, Udell Holmes, III, Ahmed Rashid, Olivier Barolette, Brittany Addison, Nicola Sambuco, Cynthia Garvan, Song Lai, Christoph Seubert, Siegfried Schmidt, Roland Staud, Jeffrey C. Edberg, David Redden, Burel R. Goodin, Catherine C. Price, Roger B. Fillingim, Kimberly T. Sibille

“…Kellgren–Lawrence scores were determined from knee radiographs, the clinical composite from fasting blood draws, and brain age from MRI data. …”
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Preliminary Design of a Tandem-Wing Unmanned Aerial System by Alejandro Sanchez-Carmona, Daniel del Río Velilla, Antonio Fernández López, Cristina Cuerno-Rejado

“…Manufacturing was carried out by combining new techniques for the use of composite materials with additive manufacturing. A wide variability in the results was identified across the different models used. …”
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Responses of Biomass and Allometric Growth Equations of Juvenile Mangrove Plants to Salinity, Flooding, and Aboveground Competition by Kaijie Hu, Wei Wang, Wei Qian, Nong Sheng, Jiliang Cheng, Yanmei Xiong

“…However, there has been a paucity of research on the growth of mangrove seedlings in a composite stress environment and the allometric growth equation of mangrove seedlings. …”
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Optimization of the Fc-fusion protein refolding method produced from the bacterial expression system by P. S. Astrelina, S. A. Ishchuk, A. V. Kabanova, R. V. Drai

“…The experiment was designed using an orthogonal composite design (Orthogonal Central Composite Design, CCO). …”
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Functional Asymmetries and Force Efficiency in Elite Junior Badminton: A Controlled Trial Using Hop Test Metrics and Neuromuscular Adaption Indices by Mariola Gepfert, Artur Gołaś, Adam Maszczyk, Kajetan Ornowski, Przemysław Pietraszewski

“…Contrary to initial hypotheses, traditional asymmetry metrics showed no significant correlations with performance variables (r < 0.1). Machine learning models (Random Forest) using FER and AII failed to classify responders reliably (AUC = 0.50). …”
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Hybrid Approach of Finite Element Method, Kigring Metamodel, and Multiobjective Genetic Algorithm for Computational Optimization of a Flexure Elbow Joint for Upper-Limb Assistive D... by Duc Nam Nguyen, Thanh-Phong Dao, Ngoc Le Chau, Van Anh Dang

“…The optimization problem considers three design variables and two objective functions. An efficient hybrid optimization approach of central composite design (CDD), finite element method (FEM), Kigring metamodel, and multiobjective genetic algorithm (MOGA) is developed. …”
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Predicted quality benefits of achievable performance benchmarks of chronic heart failure care in China: results from a nationwide observational study by Xi Li, Chao Wang, Jingkun Li, Yupeng Wang, Xiaoqiang Bao, Meina Liu, Qiuju Zhang, Chang Yin, Xudong Ma

“…Objectives This study aimed to set a data-driven achievable performance benchmark, explore the process–outcome association and speculate about the net gain in quality improvement with benchmarking.Design Observational study.Setting Patient survey conducted at 466 secondary and tertiary hospitals across 31 provinces, autonomous regions and municipalities in China.Participants 183 334 patients diagnosed with chronic heart failure (CHF) who were treated at 466 Chinese hospitals from January 2011 through May 2017.Primary independent variables Hospital process composite performance (HPCP).Secondary independent variables Patient-level and hospital-level characteristics.Primary outcome measure Patients getting better or recovered after treatment, in-hospital mortality, length of hospital stay (LOS) and medical cost.Methods HPCP was calculated using denominator-based weights. …”
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Optimization of Ultrasonic Extraction of Phenolic Compounds from Epimedium brevicornum Maxim Using Response Surface Methodology and Evaluation of Its Antioxidant Activities In Vitr... by Yan Zhao, Yingying Hou, Guosheng Tang, Enbo Cai, Shuangli Liu, He Yang, Lianxue Zhang, Shijie Wang

“…The ultrasound-assisted extraction of phenolic compounds from Epimedium brevicornu Maxim was modeled using response surface methodology. A Central Composite Design (CCD) was employed to optimize three extraction variables, including ethanol concentration (X1), extraction time (X2), and ratio of aqueous ethanol to raw material (X3), for the achievement of high extraction yield of the phenolic compounds. …”
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Optimization of ultrasound assisted extraction of sappan (Caesalpinia sappan L) wood for preparation of high quality extract by Moh Djaeni, Setia Budi Sasongko, Devi Yuni Susanti, F Widhi Mahatmanti, Andri Cahyo Kumoro, Laeli Kurniasari

“…Additionally, the extraction process was modeled, resulting in a validated effective diffusivity (De) of 1.8 × 10?? …”
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Service quality management, coach knowledge through achievement motivation, and pencak silat student satisfaction in Kazakhstan by Agung Nugroho, Djoko Pekik Irianto, Lismadiana Lismadiana, Awan Hariono, Hary Widodo

“…A correlational quantitative approach was employed, utilizing Structural Equation Modeling (SEM) with Smart-PLS software. The subjects in the study amounted to 150 pencak silat athletes. …”
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Optimization of dark chocolate formulation with roasted coriander cake as cocoa substitute by Javad Cheragheshahi, Ali Mohamadi Sani, Elham Mahdian, Sharareh Mohseni, Zahra Nazari

“…According to the results, the fitted models illustrated a desirable coefficient of determination (≥90 %).The optimization of the variables indicated that using RCC 6.08 g, Sugar 14.68 g, and Cocoa 12.23 g produced the optimized RCC chocolate with the highest desirability while maintaining the quality characteristics without undesirable changes. …”
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Temperature Control for a Proton-Exchange Membrane Fuel Cell System with Unknown Dynamic Compensations by Yashan Xing, Ramon Costa-Castelló, Jing Na

“…Moreover, there are unknown modelling errors, external disturbance and noise during modelling and experiment processes for fuel cells. …”
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OrthoKnow-SP: A Large-Scale Dataset on Orthographic Knowledge and Spelling Decisions in Spanish Adults by Jon Andoni Duñabeitia

“…A composite difficulty index integrating speed and accuracy further allowed fine-grained item ranking. …”
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Determination of the effect of alkaline chemical modification using sodium hydroxide on the acoustic and thermal properties of bagasse fibers by Roohalah Hajizadeh, Amirhossein Montazeri, Mehrana Esnaasharieh, Mohammad Hossein Beheshti, Zeinab Garavand

“…Additionally, after conducting the experiments, analysis of variance (ANOVA) was used to develop models describing the relationships between the investigated parameters and response variables to predict optimal conditions. …”
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Spray drying of buriti oil-in-water emulsions as potential systems for the delivery of bioactive compounds by Greilis Quintero-Gamero, Francis S. Sánchez-Garzón, Aureliano Rodríguez-Cortina, María Hernández-Carrión, Luz Stella Nerio

“…Based on the adjusted quadratic models of response variables, the optimal conditions were determined: SPI 5.45 % w/w and drying temperature of 180 °C, with a low predictive error and a desirability of 0.884. …”
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Prognostic significance of eosinophil-to-platelet ratio and C-reactive protein in predicting adverse events during acute exacerbations of chronic obstructive pulmonary disease: A c... by M Yogesh, D Kadalarasu, Naresh Makwana, Iva S. Chatterjee

“…Differences between groups were analysed using t-tests and regression modelling. Results EPR <0.755 and CRP ≥15.8 mg/dL were significant predictors of adverse events after adjustment, with EPR having an AUC of 0.79 and CRP an AUC of 0.68 for composite outcomes. …”
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Environmental microbial reservoir influences the bacterial communities associated with Hydra oligactis by Jay Bathia, Máté Miklós, István Gyulai, Sebastian Fraune, Jácint Tökölyi

“…Correlation analyses and neutral modeling revealed that differences in Hydra microbiota are associated with differences in environmental microbiota. …”
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Medical honey for canine nasal intertrigo: A randomized, blinded, placebo-controlled, adaptive clinical trial to support antimicrobial stewardship in veterinary dermatology. by Gabrielle Brosseau, Nadia Pagé, Caroline de Jaham, Jérôme R E Del Castillo

“…The fixed effects of time, treatment, and animal-related variables on the pruritus and on each composite score, accounting for random dog effect, were estimated separately with generalized linear mixed models for repeated count outcomes (α = 0.05). …”
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Living well with diabetes in Alaska by Meera L. Narayanan, Peter Holck, Ai-Ling Lin, Cynthia D. Schraer

“…We used records in a diabetes registry and clinical and demographic variables in our analyses. We used logistic regression and Cox Proportional Hazards models to evaluate associations of these parameters with death and complications that occurred prior to 2013. …”
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A Quantitative Evaluation of UAV Flight Parameters for SfM-Based 3D Reconstruction of Buildings by Inho Jo, Yunku Lee, Namhyuk Ham, Juhyung Kim, Jae-Jun Kim

“…Under controlled environmental conditions on representative building structures, key variables were manipulated, and all collected data were processed through a consistent SfM pipeline based on the SIFT algorithm. …”
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