A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression by Ruba Almaghrabi, Yara Alyahyawi, Peter Keane, Syed A. Mian, Khadidja Habel, Amelia Atkinson, Carl Ward, Rachel Bayley, Claudia Sargas, Pablo Menendez, George J. Murphy, Turki Sobahy, Mohammed A. Baghdadi, Arwa F. Flemban, Saeed M. Kabrah, Raul Torres-Ruiz, Eirini P. Papapetrou, Ildem Akerman, Manoj Raghavan, Eva Barragan, Dominique Bonnet, Constanze Bonifer, Paloma Garcia

“…Our work identifies mutant CEBPA as causative for MDS disease progression, providing a new isogenic MDS experimental model for drug screening to improve diagnostic and therapeutic strategies.…”
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Response Surface Methodology: Optimisation of Antifungal Bioemulsifier from Novel Bacillus thuringiensis by Deepak Rajendran, Ponnusami Venkatachalam, Jayapradha Ramakrishnan

“…A quadratic equation was employed to express the response variable in terms of the independent variables. Statistical tools like student’s t-test, F-test, and ANOVA were employed to identify the important factors and to test the adequacy of the model. …”
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Genomic organization, domain assortments, and nucleotide-binding domain diversity of NLR proteins in Sordariales fungi. by Lucas Bonometti, Florian Charriat, Noah Hensen, Silvia Miñana-Posada, Hanna Johannesson, Pierre Gladieux

“…Fungal NLRs are characterized by a great variability of domain organizations, but the identity of the nucleotide-binding domains, the genomic localization, and the factors associated with variation in the composition of repertoires of fungal NLRs are not yet fully understood. …”
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Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1. by Mohlopheni J Marakalala, Simon Vautier, Joanna Potrykus, Louise A Walker, Kelly M Shepardson, Alex Hopke, Hector M Mora-Montes, Ann Kerrigan, Mihai G Netea, Graeme I Murray, Donna M Maccallum, Robert Wheeler, Carol A Munro, Neil A R Gow, Robert A Cramer, Alistair J P Brown, Gordon D Brown

“…Transcript analysis revealed that this differential requirement for Dectin-1 is due to variable adaptation of C. albicans strains in vivo, and that this results in substantial differences in the composition and nature of their cell walls. …”
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Taxed and untaxed beverage intake by South African young adults after a national sugar-sweetened beverage tax: A before-and-after study. by Michael Essman, Lindsey Smith Taillie, Tamryn Frank, Shu Wen Ng, Barry M Popkin, Elizabeth C Swart

“…We estimated beverage intake using a 2-part model that takes into consideration the biases in using ordinary least squares or other continuous variable approaches with many individuals with zero intake. …”
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Conduction Mechanisms in Polypyrrole-Copper Nanocomposites by K. Praveenkumar, T. Sankarappa, J.S. Ashwajeet, R. Ramanna, T. Sujatha, Jyoti Kattimani, G. Chandraprabha

“…Activation energy is found to be increasing with increase in copper content in the composites. Using data deviated from small polaron model, the density of states at Fermi level is calculated by employing the theory of variable range hopping of polarons due to Mott. …”
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Association between milk pump type and free fatty acid concentrations on dairy farms with automated milking systems by Hannah M. Woodhouse, Stephen J. LeBlanc, Trevor J. DeVries, Karen J. Hand, David F. Kelton

“…A linear regression analysis was conducted with monthly average FFA as the outcome and pump type as the explanatory variable of interest, with other factors identified in previous research to be associated with increased FFA accounted for in the model. …”
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Innovative Resource-Saving Equipment for Safflower Processing to Improve Oil Quality by Maigul Mursalykova, Gulnara Kokayeva, Mukhtarbek Kakimov, Bożena Gajdzik, Radosław Wolniak, Damian Dzienniak, Michał Bembenek

“…The regression model revealed a nonlinear (quadratic) relationship between pressing time and oil yield, suggesting that there is an optimal pressing duration. …”
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Seasonal shifts in depth-to-water uptake by young thinned and overstocked lodgepole pine (<i>Pinus contorta</i>) forests under drought conditions in the Okanagan Valley, British Co... by E. C. Ellis, R. D. Guy, X. A. Wei

“…Existing reports are highly variable by climatic region, species, and thinning intensity. …”
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Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes by Sara Gutiérrez Fernández, Cristina Gan Oria, Dieter Petit, Wim Annaert, John M. Ringman, Nick C. Fox, Natalie S. Ryan, Lucía Chávez-Gutiérrez

“…Understanding this clinical variability is crucial for understanding disease mechanisms, developing predictive models and tailored interventions in ADAD, with potential implications for sporadic AD. …”
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基于TYCON的变速箱动力学仿真 by 邓晓龙, 刘国庆

“…In order to study the dynamic characteristics of the gearbox,TYCON has been used to construct the model,considering main influence factors such as the time-varying mesh stiffness,mesh damping,composite gear error,dynamic input and loading,torsional and bending stiffness of shafts,etc.Through dynamic simulation of steady and speed irregularity conditions,the variation of the key variable parameters,such as angular velocities,accelerations,torques of the shafts and gears had been gained.The system with enhanced and weakened third shafts have been simulated.…”
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Multivariate neural markers of individual differences in thought control difficulties by Jacob DeRosa, Harry R. Smolker, Hyojeong Kim, Boman Groff, Jarrod Lewis-Peacock, Marie T. Banich

“…Moreover, the exact pattern that characterizes these operations is distinct across four sets of brain regions, referred to as working memory operation networks, that include a Visual Network (VN), Somatomotor Network (SMN), Default Mode Network (DMN), and Frontoparietal Control Network (FPCN). …”
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Optimization of Particle Size and Addition of Vinasse Waste to Improve Characteristics of Rice Husk Charcoal Briquettes by Sintha Soraya Santi, Tsania Putri Azzahra, Dian Rizka Salfana, Timotius Pasang

“…This study aims to determine the optimal conditions for the particle size of husk charcoal and the addition of vinasse waste as an independent variable, using the Response Surface Methodology and the Central Composite Design (CCD) method on Design Expert 13 software. …”
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MilkOligoCorpus: A semantically annotated resource for knowledge extraction on mammalian milk oligosaccharides. by Mathilde Rumeau, Marine Courtin, Robert Bossy, Clara Sauvion, Valentin Loux, Mouhamadou Ba, Christelle Knudsen, Sylvie Combes, Claire Nédellec, Louise Deléger

“…To this end, we propose MilkOligoCorpus, a new gold standard for milk oligosaccharide composition in mammalian species. MilkOligoCorpus' annotation scheme is a rich entity/relation model designed to describe the diversity pattern of milk oligosaccharides according to female factor variability and to help better understand the structure-related function of milk oligosaccharides. …”
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The Effect of the Perceived Organizational Climate on Job Burnout According to the Moderating Role of Social Support in the Employees of Selected Health Centers in Arak City by Atefeh Nobakht, Azita Salarian, Nader Khalesi

“…Demographic information forms, Maslach's (1993) job burnout questionnaire, Halpin and Kraft's (1963) organizational climate questionnaire, and Zimmet's (1988) perceived social support questionnaire were used to collect data. The results of model structure reliability tests, Cronbach's alpha values, composite reliability values, and rho_a, which indicate the internal correlation of questions of a variable within the model, are higher than 0.7 and have acceptable structure reliability. …”
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Global Fixed-Time Horizontal Tracking Control of AUV Under Parameter Perturbation and Input Quantization by Sunwei Jiang, Shuxuan Liu, Zhicheng Liu, Quanming Miao

“…By integrating the backstepping technique with non-singular terminal sliding mode control, composite disturbances are estimated using a fixed-time neural network disturbance observer. …”
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Хронический бронхит непрофессионального генеза и вовлеченность молекулярно-генетических факторов в его патогенез... by А. В. Храмцов, В. П. Иванов, Е. В. Трубникова, О. Н. Бачинский, Н. В. Стабровская, Н. В. Кононыхина

“…Shown thаt changing the quantitative characteristics of molecular composition of erythrocyte membranes affects indicators of cytogenetic variability in patients with chronic bronchitis of unprofessional etiology. …”
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Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms by Lamiae Azouggagh, Noelia Ibáñez-Escriche, Marina Martínez-Álvaro, Luis Varona, Joaquim Casellas, Sara Negro, Cristina Casto-Rebollo

“…The Iberian pig breed, known for its high-quality meat products, includes various strains with recognized genetic and phenotypic variability. However, despite the microbiome’s known impact on pigs’ productive phenotypes such as meat quality traits, comparative analyses of gut microbial composition across Iberian pig strains are lacking. …”
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The ocular surface microbiome of rhesus macaques by Joelle K. Hass, Arthur G. Fernandes, Michael J. Montague, Armando Burgos-Rodriguez, Melween I. Martinez, Lauren J. N. Brent, Noah Snyder-Mackler, John Danias, Gadi Wollstein, James P. Higham, Amanda D. Melin

“…Here, we provide the first study of the OSM of rhesus macaques, a premier animal model for eye health and disease. We describe the taxonomy of the rhesus macaque OSM, and explore compositional correlations with age, sex, and living condition. …”
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Reconstruction of the core and extended regulons of global transcription factors. by Yann S Dufour, Patricia J Kiley, Timothy J Donohue

“…To address this question, we used a comparative genomics approach that takes advantage of the large number of sequenced bacterial genomes to predict conserved and variable members of transcriptional regulatory networks across phylogenetically related organisms. …”
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