The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass by Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément

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Landing scheduling for carrier aircraft fleet considering bolting probability and aerial refueling by Genlai Zhang, Lei Wang, Zhilong Deng, Xuanbo Liu, Xichao Su, Haixu Li, Chen Lu, Kai Liu, Xinwei Wang

“…Then, taking the landing sequencing as decision variables, a combinatorial optimization model with a compound objective function is formulated. …”
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Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Methods‍　‍The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
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A Hybrid RBF-PSO Framework for Real-Time Temperature Field Prediction and Hydration Heat Parameter Inversion in Mass Concrete Structures by Shi Zheng, Lifen Lin, Wufeng Mao, Yanhong Wang, Jinsong Liu, Yili Yuan

“…These findings guided a phased optimization strategy, as follows: prioritizing high-precision calibration of dominant parameters while relaxing constraints on low-sensitivity variables, thereby balancing accuracy and computational efficiency. …”
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Optimization Design of the Transmission System of Small-size Shrub Brush Cutter based on MATLAB by Yang Chunmei, Guo Minghui, Ma Yan, Liu Qianjun, Yang Tie

“…By determining the objective function of the transmission system,selecting the independent design variables,determining the constraints,the mathematical model of transmission system is established.The analysis and optimization of the design variables,objective function and the boundary conditions are carried out,the complex method optimization program of MATLAB is written,and by using its powerful ability of optimization design to optimize the transmission system of the brush cutter. …”
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ITER NBI operational window and power availability constraints due to shine-through losses by P. Vincenzi, M. Schneider, P. Veltri, J.F. Artaud, A. Loarte, S. Nicolici, C. Poggi, A.R. Polevoi, A. Snicker

“…We then present a new heuristic formula which permits the calculation of the ST fraction and the minimum plasma density that permits ITER NBI operations as a function of global variables. This allows for establishing operational limits for Hydrogen and Deuterium NBI in Hydrogen, Deuterium, and Deuterium–Tritium plasmas. …”
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Human saliva exerts strong type-dependent effects on adenovirus infectivity by Erwan Sallard, Wenli Zhang, Nikita Chilakamarri, Setareh Farzanehkari, Setareh Farzanehkari, Inga Marte Charlott Seuthe, Anja Ehrhardt, Malik Aydin, Malik Aydin

“…All human Ads used were replication-competent and expressed a GLN cassette containing a green-fluorescent protein, nano-luciferase, and neomycin resistance. Loss-of-function experiments were conducted by immunoprecipitation or enzymatic digestion of specific saliva components to decipher related mechanisms.ResultsTemporal and inter-individual variability in saliva samples were observed, validating the use of a saliva pool to represent the population. …”
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Sinc-Chebyshev Collocation Method for a Class of Fractional Diffusion-Wave Equations by Zhi Mao, Aiguo Xiao, Zuguo Yu, Long Shi

“…Through the numerical example, the procedure is tested and the efficiency of the proposed method is confirmed.…”
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Optimal selection of satellite XCO₂ images for urban CO₂ emission monitoring by A. Danjou, G. Broquet, A. Schuh, F.-M. Bréon, T. Lauvaux, T. Lauvaux

“…This study analyzes the performances of an automated method for estimating urban emissions as a function of the targeted cities and of the atmospheric conditions. …”
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A Study of Some Properties of Fuzzy Laplace Transform with Their Applications in Solving the Second-Order Fuzzy Linear Partial Differential Equations by Elhassan Eljaoui, Said Melliani

“…Then, some properties dealing with the partial derivatives of fuzzy Laplace transform for a fuzzy function of two real variables have been proved. Afterwards, an algorithm of fuzzy Laplace transform for solving second-order fuzzy partial differential equations has been proposed. …”
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A Novel Multi-Dynamic Coupled Neural Mass Model of SSVEP by Hongqi Li, Yujuan Wang, Peirong Fu

“…Steady-state visual evoked potential (SSVEP)-based brain—computer interfaces (BCIs) leverage high-speed neural synchronization to visual flicker stimuli for efficient device control. While SSVEP-BCIs minimize user training requirements, their dependence on physical EEG recordings introduces challenges, such as inter-subject variability, signal instability, and experimental complexity. …”
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Mechatronic system for running-in and testing of mechanical transmissions in mining shovels by Sergey I. Malafeev, Alevtina A. Malafeeva, Vladimir I. Konyashin, Andrey A. Novgorodov

“…Interactive manual control, enabling the operator to verify the functionality and calibration of test bench components. 2. …”
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A nomogram for diagnosis of BI-RADS 4 breast nodules based on three-dimensional volume ultrasound by Xianping Jiang, Chen Chen, Jincao Yao, Liping Wang, Chen Yang, Wei Li, Di Ou, Zhiyan Jin, Yuanzhen Liu, Chanjuan Peng, Yifan Wang, Dong Xu

“…It can function as a relatively accurate predictive tool for sonographers and clinicians and is therefore clinically useful. …”
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Supply chain management and optimization in transportation logistics by Saoussen Krichen

“…</em></p><p><em>2)     </em><em>Unconstrained decision problems that consist of minimizing or maximizing a function. The main concern is the finding of the solution value that corresponds to the global optimum. …”
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An evolutionary-based optimization algorithm for truss sizing design by Pham Hoang Anh

“…Here, the constraints and objective function are treated separately so that both function and constraint evaluations can be saved. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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Flow Characteristics of Distinctly Viscous Multilayered Intestinal Fluid Motion by S. K. Pandey, M. K. Chaube, Dharmendra Tripathi

“…The effects of power law index and viscosities on pressure across one wavelength, mechanical efficiency, and trapping are discussed numerically. …”
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High-accuracy solution of pantograph differential equations subject to mixed boundary conditions via shifted Vieta–Lucas polynomials by R. M. Hafez, H. M. Ahmed

“…A Galerkin method (GM) is formulated for constant coefficient-type equations, and a spectral collocation method (SCM) is given for variable coefficient cases. The basis functions are developed to fulfill the given MTBCs, which reduces implementation and enhances accuracy. …”
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Optimisation of the performance and structure of soluble ball seat metal sealing rings based on response surface by CHEN Zhen, RAN Qingjie, CHEN Nengpeng, WANG Qiaomu

“…Horizontal well fracturing technology, as a core tool for efficient development of tight oil and gas reservoirs, is of strategic significance for enhancing the recovery rate of unconventional oil and gas resources. …”
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Immunological Avalanches in Renal Immune Diseases by Davide Viggiano, Pietro Iulianiello, Antonio Mancini, Candida Iacuzzo, Luca Apicella, Renata Angela Di Pietro, Sarah Hamzeh, Giovanna Cacciola, Eugenio Lippiello, Andrea Gigliotti, Carmine Secondulfo, Giancarlo Bilancio, Giuseppe Gigliotti

“…Two distinct dynamic patterns emerged: large oscillations in eGFR, proteinuria, or biological age predicted declining function, while small oscillations indicated stability. …”
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