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Supply chain management and optimization in transportation logistics
Published 2022-12-01“…SCM can also be seen as the process of optimizing a set of decisions that generate cost-effective solutions which provide efficient plans for acting on numerous levels while considering all decision-making standpoints. …”
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1202
Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer
Published 2025-08-01“…We systematically dissect the multifaceted regulatory circuits governing lactate metabolism by integrating three pivotal dimensions: (i) canonical signaling cascades; (ii) tumor-microenvironmental variables, most notably hypoxia and acidosis; and (iii) the emerging epigenetic paradigm of lactylation, which dynamically reprograms the catalytic efficiency of rate-limiting enzymes and reshapes the transcriptional landscape of metabolic genes, thereby precisely coordinating lactate homeostasis. …”
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1203
Comparative Evaluation of Vibratory Physiotherapy Methods in the Early Period after Cardiac Surgery
Published 2022-01-01“…Mechanical respiratory therapy procedures led to significant improvement in gas exchange variables, as evidenced by an increase in SpO2 in Groups 1 and 2 (p = 0.000009 and 0.000001, respectively) and a decrease in the proportion of patients with impaired oxygenating lung function (SpO2 below 92%) by 11 and 12 times, respectively (p < 0.01). …”
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1204
Good Governance and Seigniorage in a Selected OPEC Countries and Iran
Published 2025-03-01“…Good governance has several positive effects on government revenues and efficiency. While the use of seigniorage may initially appear as a natural right of governments, if it leads to a faster growth rate of money compared to economic growth, it can result in inflation and impose inflationary taxes. …”
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1205
The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review
Published 2025-03-01“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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1206
Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition
Published 2025-01-01“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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1207
Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-...
Published 2024-12-01“…Importantly, not all types of aluminosilicates have the same decontaminating efficiency; thus, a full characterization of the protective properties of each single material would assist in selecting the most appropriate binder. …”
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1208
AngleCam: Predicting the temporal variation of leaf angle distributions from image series with deep learning
Published 2022-11-01“…The plausibility of the predicted leaf angle time series was underlined by its close relationship with environmental variables related to transpiration. The evaluations confirm that AngleCam is a robust and efficient method to track leaf angles under field conditions. …”
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1209
A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el...
Published 2025-08-01“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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1210
New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery
Published 2025-03-01“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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1211
Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents
Published 2024-07-01“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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1212
‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’
Published 2024-11-01“…Abstract Background of the study Along with developments in the clinical domain, medical equipment is becoming more sophisticated, and it needs to function at peak efficiency. In this case, hospitals should priorities the prompt and effective maintenance of life-saving equipment. …”
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1213
Effect of Central Motor and Neuromuscular Impairments on Front Crawl Body Roll Characteristics of Para Swimmers
Published 2025-08-01“…CMNI swimmers were divided into three upper-limb [mild (n = 9), moderate (n = 9), severe (n = 9)] and three lower-limb function subgroups [bilateral (n = 2), unilateral (n = 6), without kick (n = 19)] based on their Froude efficiency (a measure of how effectively upper limbs contribute to propulsion) and the number of lower limbs actively kicking during trials, respectively. …”
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1214
Immunological Avalanches in Renal Immune Diseases
Published 2025-04-01“…Additionally, biological age calculations provide valuable prognostic information, while proteinuria measurements offer efficient sampling for system dynamics assessment. …”
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1215
Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…During this time, the number of changes in the target variables by the variables themselves decreases and the changes in the variables caused by the shock of the exchange rate channel increase. …”
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1216
Neural Network-Based Design of a Buck Zero-Voltage-Switching Quasi-Resonant DC–DC Converter
Published 2024-10-01“…The converter is a piecewise linear system mathematically described by Kirchhoff’s laws and represented through switching functions. In this way, a mathematical model is used to generate data on the behavior of the state variables obtained under various design parameters. …”
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1217
Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry
Published 2025-05-01“…Conclusions In rTOF, RV contraction fraction, a novel biomarker of ventricular efficiency, may be used to possibly improve risk stratification. …”
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1218
Coordination of technology of railway operation of the Republic of Tajikistan and organization of railways in international traffic
Published 2018-08-01“…Proposed classification of technological restrictions and controlled variables in the performance of transport takes into account methods for changing external conditions for the functioning of the railway landfill and methods for increasing internal efficiency of its operation. …”
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1219
Machine learning-based model for acute asthma exacerbation detection using routine blood parameters
Published 2025-07-01“…Background: Acute asthma exacerbations (AAEs) are a leading cause of asthma-related morbidity and mortality, especially in resource-limited settings where pulmonary function tests are unavailable or when patients are unable to cooperate with testing. …”
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1220
Hemodynamic homeostasis disequilibrium in critical illness
Published 2025-07-01“…Over millions of years, the circulatory system evolved from primitive forms into a highly specialized network capable of overcoming time-distance constraints and enhancing diffusion efficiency. This structural advancement laid the physiological foundation for the regulation of hemodynamics and systemic homeostasis. …”
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