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  1. 18681
  2. 18682
  3. 18683

    Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer by Jing Wang, Lin Li, Huicheng Liu, Lili Bai, Liu Huang, Na Ning, Yijia Li, Xuejiao Dong, Qiuyang Du, Minghui Xia, Yufei Chen, Likun Zhao, Yanhu Li, Qingwu Meng, Yaqi Duan, Jie Ming, Andy Qingan Yuan, Xiang-Ping Yang

    Published 2021-10-01
    “…Immunofluorescent staining was performed to demonstrate the interactions between T cells with TNBC cells. The cytotoxicity of T cells against TNBC cell lines and primary tumor cells mediated by F7AK3 were determined in vitro. …”
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    Article
  4. 18684

    Adolescent vaccine introductions scoping review: A decade of insights from low- and middle-income countries (2013−2023) by Arman Majidulla, Amelia K. Gerste, Anurima Baidya, Onimitein Georgewill, Kirthini K. Muralidharan, Degu J. Dare, Joeri S. Buis, Michelle M. Gill, Julie A. Denison, Andrew D. Kerkhoff, Rupali J. Limaye

    Published 2025-08-01
    “…We included English full text articles which provided insights based on primary data collection into vaccine introductions for adolescents over the past ten years (i.e., 2013 onwards). …”
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  5. 18685

    Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis by Mingzhi Hu, Tian Song, Zhaoyuan Gong, Qianzi Che, Jing Guo, Lin Chen, Haili Zhang, Huizhen Li, Ning Liang, Guozhen Zhao, Yanping Wang, Nannan Shi, Bin Liu

    Published 2025-07-01
    “…ResultsThis study analyzed 155 sets of macrolevel data from 108 clinical studies, encompassing 63,771 patients. …”
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  6. 18686

    Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus by Irfan Ahmad, Mohammed Alfaifi, Mirza Masroor Ali Beg, Ali Gaithan Alkhathami, Prakash C Joshi, Osama M Alshehri, Abdulrahman Manaa Alamri, Amit Kumar Verma, Mohammad Yahya Alshahrani

    Published 2021-03-01
    “…Serum analysis was carried out to determine differences in biochemical parameters. Recorded data were used to evaluate associations with expression of lncRNAs NF-kappaB interacting lncRNA (NKILA), nuclear enriched abundant transcript 1 (NEAT1), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and myocardial infarction-associated transcript (MIAT) in T2DM cases.Results Compared with healthy controls, patients with T2DM showed an overall increase in expression of lncRNAs NKILA, NEAT, MALAT1, and MIAT by 3.94-fold, 5.28-fold, 4.46-fold, and 6.35-fold, respectively. …”
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  7. 18687

    Predictive role of the Albumin-Bilirubin score in ICU patients with cirrhosis and sepsis: insights from a large retrospective cohort by Jianjun Wang, Pei Yang, Chuan Qin, Yongwei Huang, Zhaohui Hu, Ruizi Shi, Sirui Chen, Xi Chen, Hua Luo, Jianping Gong, Xintao Zeng, Decai Wang

    Published 2025-07-01
    “…Methods This retrospective study analyzed data from ICU patients with liver cirrhosis and sepsis admitted to the Beth Israel Deaconess Medical Center between 2008 and 2022. …”
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    Article
  8. 18688

    Genomic insights into genetic diversity and seed coat color change in common bean composite populations by Eva Plestenjak, Eva Plestenjak, Mohamed Neji, Lovro Sinkovič, Vladimir Meglič, Barbara Pipan

    Published 2025-01-01
    “…Population structure was analyzed using Fst, principal component analysis (PCA) and clustering. …”
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    Article
  9. 18689

    Development and Evaluation of a Patient–Family Caregiver Dyad mHealth Intervention for Heart Failure Self-Care: Quasi-Experimental Study by Youn-Jung Son, JiYeon Choi, Hyue Mee Kim, Hoyoun Won, Jong-Chan Youn, Sang-Wook Kim, Wang-Soo Lee, Jun Hwan Cho, Kyung‑Taek Park, Joonhwa Hong, Da-Young Kim

    Published 2025-06-01
    “…Adherence to self-care behaviors, family caregivers’ contributions to self-care behaviors, and health-related quality of life were evaluated. Data were collected using self-administered questionnaires at baseline and at 1 month, 3 months, and 6 months post enrollment. …”
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  10. 18690

    Identifying the Antecedents of Humble Leadership for Managers with a Meta-synthesis Approach by Tahereh Mohammadi, Adel Zahedbabelan, Ali Khaleghkhah, Hossein Taghavi Qarabulagh

    Published 2025-03-01
    “…Data were subjected to three-stage coding (open, axial, and selective) with the assistance of Maxqda 2020 software. …”
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  11. 18691

    Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study by Amber Watts, Amber Watts, Shannon Donofry, Shannon Donofry, Hayley Ripperger, Nicole M. Eklund, Lu Wan, Chaeryon Kang, George Grove, Lauren E. Oberlin, Lauren E. Oberlin, Swathi Gujral, Eric D. Vidoni, Jeffrey M. Burns, Edward McAuley, Edward McAuley, Charles H. Hillman, Arthur F. Kramer, Arthur F. Kramer, M. Ilyas Kamboh, Kirk I. Erickson, Kirk I. Erickson

    Published 2025-04-01
    “…We hypothesized that (1) oophorectomy prior to natural menopause would be associated with poorer cognitive performance, (2) timing and duration of birth control and menopausal hormone therapy would influence associations with cognitive performance, and (3) APOE4 carrier status would interact with oophorectomy and hormone therapy to influence cognitive performance.MethodsIn 461 post-menopausal females (M age = 69.6) we assessed oophorectomy and hormone therapy use to examine associations with the Montreal Cognitive Assessment (MoCA) and factor-analytically derived composite scores for episodic memory, processing speed, working memory, executive function/attentional control, and visuospatial processing.ResultsHypothesis (1) We did not observe associations between oophorectomy prior to natural menopause and poorer cognitive performance. …”
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  12. 18692

    Easy, fast and reproducible Stochastic Cellular Automata with chouca by Génin, Alexandre, Dupont, Guillaume, Valencia, Daniel, Zucconi, Mauro, Ávila-Thieme, M. Isidora, Navarrete, Sergio A., Wieters, Evie A.

    Published 2024-10-01
    “…Besides providing better reproducibility and accessibility, a fast engine for SCA unlocks novel, computationally intensive statistical approaches, such as simulation-based inference of ecological interactions from field data, which represents by itself an important avenue for research. …”
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  13. 18693

    New Symbiotic Stars from LAMOST DR10 Spectra and Multiband Photometry by Jing Chen, Liang Wang, Yin-Bi Li, Xiao-Xiao Ma, A-Li Luo, Zi-Chong Zhang, Ming-Yi Ding, Kai Zhang

    Published 2025-01-01
    “…Ultimately, we classified all nine as S-type SySts using the J − H versus H − K _s diagram. Additionally, based on multiband photometric data from GALEX, Gaia, Two Micron All Sky Survey, ALLWISE, and several X-ray catalogs, we found 12 accreting-only SySt (acc-SySt) candidates, characterized by concurrent ultraviolet and infrared excess and accretion process. …”
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  14. 18694

    Characterizations of multi-kingdom gut microbiota in immune checkpoint inhibitor-treated hepatocellular carcinoma by Longhao Zhang, Shanshan Wang, Yajun Liang, Xiaobo Yang, Haitao Zhao, Xinting Sang, Dongya Zhang, Zhou Lan, Hanping Wang, Ziyu Xun, Chenchen Zhang, Chengpei Zhu, Jiashuo Chao, Zilun Pu, Cong Ning, Xianzhi Jiang

    Published 2024-06-01
    “…Herein, we investigated the multi-kingdom microbiota characterization of the gut microbiome, mycobiome, and metabolome using metagenomic, ITS2, and metabolomic data sets of 80 patients with ICI-treated HCC.Results Our findings demonstrated that bacteria and metabolites differed significantly between the durable clinical benefit (DCB) and non-durable clinical benefit (NDB) groups, whereas the differences were smaller for fungi. …”
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  15. 18695

    Life cycle assessment of environment benefits in wheat production under water-saving and nitrogen-reducing practices in the North China Plain by Chao Wang, Yehan Fu, Hongge Wang, Yazhan Ren, Yunying Zhang, Yuzhao Ma, Yunzhou Qiao, Baodi Dong, Yuechen Zhang

    Published 2025-09-01
    “…Winter wheat cultivation faces yield reductions in the North China Plain due to drought and excessive nitrogen fertilizer use, exacerbated by climate change. This study employed a life cycle assessment approach, integrating economic and material input-output data, to evaluate the eco-efficiency of reduced irrigation and nitrogen fertilizer inputs. …”
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  16. 18696

    CRISPR/Cas9 mutagenesis reveals an essential role of PI4KB in promoting growth and resisting hemorrhagic disease caused by GCRV-II infection in juvenile grass carp by Jie Zhang, Liqiang Zhang, Xiaoman Wu, Minhui Tao, Yang Chen, Mingxian Chang

    Published 2025-01-01
    “…Since the negative regulatory role of gcPI4KB in GCRV infection was confirmed by in vitro data, we performed gene editing of gcPI4KB in grass carp. …”
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  17. 18697

    Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia by Zhiwei Lin, Mingshan Xue, Mingqing Lu, Shuang Liu, Yueting Jiang, Qianyue Yang, Honghui Cui, Xia Huang, Zeguang Zheng, Baoqing Sun

    Published 2025-05-01
    “…Methods We performed a comprehensive proteomic and metabolomic analysis on clinical samples from patients diagnosed with P. aeruginosa pneumonia, including both bronchoalveolar lavage fluid (BALF) and serum to capture local and systemic host responses. Data were analyzed using advanced statistical techniques to identify differentially expressed proteins and metabolites. …”
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  18. 18698

    <i>Achnatherum inebrians</i> Bacterial Communities Associated with <i>Epichloë gansuensis</i> Endophyte Infection Under Low-Concentration Urea Treatment: Links to Plant Growth and... by Yuanyuan Jin, Zhenjiang Chen, Kamran Malik, Chunjie Li

    Published 2025-06-01
    “…Overall, our results suggest that the E+ plants had more root forks and greater average root diameter compared to E− plants under the UN treatment. In a pot experiment using UN, data from 16S rRNA amplicon sequencing revealed that <i>E. gansuensis</i> endophyte infection significantly altered the bacterial community composition in shoot and root, and significantly increased Shannon (<i>p</i> < 0.001) and Chao 1 (<i>p</i> < 0.01) indexes. …”
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  19. 18699
  20. 18700

    MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma by Yan Jiang, Zhengyu Shu, Lei Cheng, Lei Cheng, Haowei Wang, Taiping He, Liwen Fu, Chao Zhao, Xuefei Li, Weicheng Zeng, Weicheng Zeng

    Published 2025-04-01
    “…Given the promising prediction value of metabolism-related genes in LUAD, this study aims to explore the role of MS4A7, a member of the MS4A gene family, in LUAD prognosis and immune microenvironment dynamics.MethodsA prognostic signature for LUAD was developed using the LASSO-Cox regression algorithm with RNA-seq data from 500 LUAD patients in The Cancer Genome Atlas database. …”
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