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18681
Mosquito-based detection of retroviruses and arboviruses in Senegal: expanding the scope of xenosurveillance
Published 2025-06-01“…Blood-fed mosquitoes were pooled and subjected to RNA extraction and metagenomic sequencing using Illumina NextSeq550. Sequencing data were analyzed with CZ-ID and BLAST for viral identification. …”
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18682
Detection of Molecular Clouds in the PeVatron Candidate Source LHAASO J0341+5258 by the Nobeyama 45-m Radio Telescope
Published 2025-01-01“…We report a new CO observation survey of LHAASO J0341+5258, using the Nobeyama Radio Observatory 45-m telescope. …”
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18683
Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer
Published 2021-10-01“…Immunofluorescent staining was performed to demonstrate the interactions between T cells with TNBC cells. The cytotoxicity of T cells against TNBC cell lines and primary tumor cells mediated by F7AK3 were determined in vitro. …”
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18684
Adolescent vaccine introductions scoping review: A decade of insights from low- and middle-income countries (2013−2023)
Published 2025-08-01“…We included English full text articles which provided insights based on primary data collection into vaccine introductions for adolescents over the past ten years (i.e., 2013 onwards). …”
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18685
Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis
Published 2025-07-01“…ResultsThis study analyzed 155 sets of macrolevel data from 108 clinical studies, encompassing 63,771 patients. …”
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18686
Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus
Published 2021-03-01“…Serum analysis was carried out to determine differences in biochemical parameters. Recorded data were used to evaluate associations with expression of lncRNAs NF-kappaB interacting lncRNA (NKILA), nuclear enriched abundant transcript 1 (NEAT1), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and myocardial infarction-associated transcript (MIAT) in T2DM cases.Results Compared with healthy controls, patients with T2DM showed an overall increase in expression of lncRNAs NKILA, NEAT, MALAT1, and MIAT by 3.94-fold, 5.28-fold, 4.46-fold, and 6.35-fold, respectively. …”
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18687
Predictive role of the Albumin-Bilirubin score in ICU patients with cirrhosis and sepsis: insights from a large retrospective cohort
Published 2025-07-01“…Methods This retrospective study analyzed data from ICU patients with liver cirrhosis and sepsis admitted to the Beth Israel Deaconess Medical Center between 2008 and 2022. …”
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18688
Genomic insights into genetic diversity and seed coat color change in common bean composite populations
Published 2025-01-01“…Population structure was analyzed using Fst, principal component analysis (PCA) and clustering. …”
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18689
Development and Evaluation of a Patient–Family Caregiver Dyad mHealth Intervention for Heart Failure Self-Care: Quasi-Experimental Study
Published 2025-06-01“…Adherence to self-care behaviors, family caregivers’ contributions to self-care behaviors, and health-related quality of life were evaluated. Data were collected using self-administered questionnaires at baseline and at 1 month, 3 months, and 6 months post enrollment. …”
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18690
Identifying the Antecedents of Humble Leadership for Managers with a Meta-synthesis Approach
Published 2025-03-01“…Data were subjected to three-stage coding (open, axial, and selective) with the assistance of Maxqda 2020 software. …”
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18691
Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study
Published 2025-04-01“…We hypothesized that (1) oophorectomy prior to natural menopause would be associated with poorer cognitive performance, (2) timing and duration of birth control and menopausal hormone therapy would influence associations with cognitive performance, and (3) APOE4 carrier status would interact with oophorectomy and hormone therapy to influence cognitive performance.MethodsIn 461 post-menopausal females (M age = 69.6) we assessed oophorectomy and hormone therapy use to examine associations with the Montreal Cognitive Assessment (MoCA) and factor-analytically derived composite scores for episodic memory, processing speed, working memory, executive function/attentional control, and visuospatial processing.ResultsHypothesis (1) We did not observe associations between oophorectomy prior to natural menopause and poorer cognitive performance. …”
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18692
Easy, fast and reproducible Stochastic Cellular Automata with chouca
Published 2024-10-01“…Besides providing better reproducibility and accessibility, a fast engine for SCA unlocks novel, computationally intensive statistical approaches, such as simulation-based inference of ecological interactions from field data, which represents by itself an important avenue for research. …”
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18693
New Symbiotic Stars from LAMOST DR10 Spectra and Multiband Photometry
Published 2025-01-01“…Ultimately, we classified all nine as S-type SySts using the J − H versus H − K _s diagram. Additionally, based on multiband photometric data from GALEX, Gaia, Two Micron All Sky Survey, ALLWISE, and several X-ray catalogs, we found 12 accreting-only SySt (acc-SySt) candidates, characterized by concurrent ultraviolet and infrared excess and accretion process. …”
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18694
Characterizations of multi-kingdom gut microbiota in immune checkpoint inhibitor-treated hepatocellular carcinoma
Published 2024-06-01“…Herein, we investigated the multi-kingdom microbiota characterization of the gut microbiome, mycobiome, and metabolome using metagenomic, ITS2, and metabolomic data sets of 80 patients with ICI-treated HCC.Results Our findings demonstrated that bacteria and metabolites differed significantly between the durable clinical benefit (DCB) and non-durable clinical benefit (NDB) groups, whereas the differences were smaller for fungi. …”
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18695
Life cycle assessment of environment benefits in wheat production under water-saving and nitrogen-reducing practices in the North China Plain
Published 2025-09-01“…Winter wheat cultivation faces yield reductions in the North China Plain due to drought and excessive nitrogen fertilizer use, exacerbated by climate change. This study employed a life cycle assessment approach, integrating economic and material input-output data, to evaluate the eco-efficiency of reduced irrigation and nitrogen fertilizer inputs. …”
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18696
CRISPR/Cas9 mutagenesis reveals an essential role of PI4KB in promoting growth and resisting hemorrhagic disease caused by GCRV-II infection in juvenile grass carp
Published 2025-01-01“…Since the negative regulatory role of gcPI4KB in GCRV infection was confirmed by in vitro data, we performed gene editing of gcPI4KB in grass carp. …”
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18697
Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia
Published 2025-05-01“…Methods We performed a comprehensive proteomic and metabolomic analysis on clinical samples from patients diagnosed with P. aeruginosa pneumonia, including both bronchoalveolar lavage fluid (BALF) and serum to capture local and systemic host responses. Data were analyzed using advanced statistical techniques to identify differentially expressed proteins and metabolites. …”
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18698
<i>Achnatherum inebrians</i> Bacterial Communities Associated with <i>Epichloë gansuensis</i> Endophyte Infection Under Low-Concentration Urea Treatment: Links to Plant Growth and...
Published 2025-06-01“…Overall, our results suggest that the E+ plants had more root forks and greater average root diameter compared to E− plants under the UN treatment. In a pot experiment using UN, data from 16S rRNA amplicon sequencing revealed that <i>E. gansuensis</i> endophyte infection significantly altered the bacterial community composition in shoot and root, and significantly increased Shannon (<i>p</i> < 0.001) and Chao 1 (<i>p</i> < 0.01) indexes. …”
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18699
Contribution of depression and cardiometabolic diseases and the role of depression treatment in survival and functioning in older adultsResearch in context
Published 2025-04-01“…Methods: We used data from the ASPREE trial and its observational follow-ups (2010–2019), involving community-dwelling adults aged ≥ 70 years (≥65 for U.S. minorities). …”
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18700
MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma
Published 2025-04-01“…Given the promising prediction value of metabolism-related genes in LUAD, this study aims to explore the role of MS4A7, a member of the MS4A gene family, in LUAD prognosis and immune microenvironment dynamics.MethodsA prognostic signature for LUAD was developed using the LASSO-Cox regression algorithm with RNA-seq data from 500 LUAD patients in The Cancer Genome Atlas database. …”
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