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18341
Associations of blood-based biomarkers of neurodegenerative diseases with mortality, cardio- and cerebrovascular events in persons with chronic coronary syndrome
Published 2025-02-01“…Methods: We used data from a cohort of persons with CCS for whom major adverse events were recorded over a follow-up of 20 years. …”
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18342
Spatio-temporal dynamics of Isoberlinia-dominated woodlands in disturbance-prone landscapes over 15 years
Published 2025-06-01“…We calculated species richness and density for sapling and adult trees, and estimated two main variables: potential productivity using water deficit as a proxy, and disturbance intensity using logging rate. …”
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18343
Deep Multi-Modal Skin-Imaging-Based Information-Switching Network for Skin Lesion Recognition
Published 2025-03-01“…The diagnostic potential of recent multi-modal skin lesion detection algorithms is limited because they ignore dynamic interactions and information sharing across modalities at various feature scales. …”
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18344
Baseline-dependent network reactivity to visual input in children with autism spectrum disorder: a magnetoencephalography study
Published 2025-07-01“…MEG signals were mapped to 68 cortical regions using the Desikan–Killiany atlas, and functional connectivity was assessed using the phase lag index across five frequency bands (delta, theta, alpha, beta, and gamma). …”
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18345
Determination of high-grade serous ovarian cancer stem cell-based subtypes and prognostic model and identification of highly expressed VSIG4 and STAB1 in macrophages
Published 2025-07-01“…Macrophage subpopulations were identified using single cell data, and pseudo-time analysis revealed the changes of macrophages during cell state transition. …”
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18346
Co-designing a peer support programme for carers of people treated under the Mental Health Act: views from stakeholders
Published 2025-05-01“…Audio recordings of the interviews were transcribed, and data were analysed using thematic analysis. Results Five themes were identified: (a) carer availability and awareness; (b) peer support flexibility; (c) early promotion of peer support; (d) appropriate training and support for peers, and; (e) anticipated impact of peer support. …”
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18347
Tracing Coherent Gas Structures in the Central Region of the Starburst Galaxy NGC 253. II. Gas Excitation and Star Formation
Published 2025-01-01“…Molecular gas in the central region of the starburst galaxy NGC 253 is complicated because of the combination of different gas kinematics, including stellar feedback, noncircular motions, and magnetic activity. In paper I, we used the latest multitransition, multi-isotope CO-line data sets obtained with the Atacama Large Millimeter/submillimeter Array to classify the molecular gas within the central 850 pc in radius into 28 coherent structures, and we proposed a three-dimensional geometric structure for the gas in the central region of this galaxy. …”
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18348
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18349
Association of Personal Care and Consumer Product Chemicals with Long-Term Amenorrhea: Insights into Serum Globulin and STAT3
Published 2025-03-01“…Various statistical models for robustness tests and mediation analysis were used to explore associations with long-term amenorrhea and the role of serum globulin. …”
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18350
Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors
Published 2024-12-01“…A library of 1463 natural compounds from AfroDb and NANPDB, prefiltered based on Lipinski’s rules, was used to screen against the LmPTR1 target. The X-ray structure of LmPTR1 complexed with NADP and dihydrobiopterin (Protein Data Bank ID: 1E92) was identified to contain the critical residues Arg17, Leu18, Ser111, Phe113, Pro224, Gly225, Ser227, Leu229, and Val230 including the triad of residues Asp181-Tyr194-Lys198, which are critical for the catalytic process involving the reduction of dihydrofolate to tetrahydrofolate. …”
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18351
Depth distributions of soil temperature: Seasonal sensitivity and simulation across dryness/wetness conditions
Published 2025-07-01“…Using long-term monthly observations (1966–2022) from the Wudaogou National Comprehensive Hydrological Observation Station in Anhui Province, China, we analyzed the soil temperature at depths of 0–320 cm paired with meteorological data. …”
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18352
CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target
Published 2024-12-01“…Methods The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, CELL and GEO databases were utilized to explore the distribution of the CYFIP2 gene in human cancers. Data were analyzed using a variety of web-based platforms and software such as R (4.3.2), UCSC, MethSurv, Cytoscape (v3.10.2), UALAND, STRING, TISIDB, Harmonizome 3.0, TIMER 2.0, TCIA and TIDE. …”
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18353
Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma
Published 2025-04-01“…We subsequently developed a network of protein–protein interactions and established the densely interconnected clusters (core genes) underlying the network using these differentially expressed genes (DEGs). …”
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18354
3-O Sulfated Heparan Sulfate (G2) Peptide Ligand Impairs the Infectivity of <i>Chlamydia muridarum</i>
Published 2025-07-01“…Furthermore, molecular dynamics simulations were conducted to investigate the interactions of the <i>Chlamydia</i> lipid bilayer membrane with the G1 and G2 peptides, focusing on their binding modes and affinities. …”
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18355
Understanding Gender-Specific Daily Care Preferences: Topic Modeling Study
Published 2025-05-01“…ObjectiveThis study aims to identify and analyze the key themes and daily care preferences from unstructured adult text narratives with a focus on uncovering gender-specific variations. MethodsThis study used 4350 deidentified, unstructured textual data from MyDirectives (MyDirectives, Inc), an interactive online platform. …”
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18356
Fungal Footprints: Soil Fungal Communities in Black Walnut and Red Oak Forests
Published 2024-10-01“…Our study underscores that grasping these specific interactions is essential for effective forest management, especially when considering how to use fungal communities to boost plant growth. …”
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18357
Dog-assisted interventions to support health and wellbeing: a national survey of current practice in England
Published 2025-08-01“…IntroductionIn England, dog-assisted interventions (DAIs) are increasingly used to support the health and wellbeing of individuals with mental and physical health conditions. …”
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Rethinking of the Ornament in rural house (Case study: Ovan village in Qazvin)
Published 2018-09-01“…Qualitative research generally refers to research whose findings have not been obtained through statistical processes and for quantitative purposes. The data of this type of research is collected through observation, interviewing or oral interactions, and focuses on the meanings and contributions of the participants. …”
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18360
Exploring cultural competence knowledge, skills, and comfort among male nursing students in Riyadh, Saudi Arabia
Published 2025-07-01“…Methods A cross-sectional, descriptive paper-based study was conducted among male nursing students at a Saudi University between March and May 2024. Data was collected using structured, pre-validated 47-item questionnaires and analyzed using the statistical package for social science version 27. …”
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