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  1. 18181
  2. 18182

    Community coalitions’ navigation of policies to address the opioid epidemic: insights from qualitative interviews in four states by Elizabeth N Kinnard, Ann Scheck McAlearney, Timothy Hunt, Ramona G Olvera, Allyson G Cogan, Mary Bartkus, Shoshana N Benjamin, Jill Davis, Lisa A Frazier, Brandy F Henry, Hallie Mattingly, Dean Rivera, Mari-Lynn Drainoni, Daniel M Walker

    Published 2025-04-01
    “…However, limited research has explored these public health-oriented community coalitions and their interactions with the policy landscape. This study explores how cross-sector public health-oriented community coalition members perceive and navigate the multidimensional policy landscapes to address the opioid epidemic.Methods Using data from 304 semistructured HEALing Communities Study coalition member interviews conducted April–June 2021 in 67 communities in Kentucky, New York, Massachusetts and Ohio, we inductively analysed participants’ discussions of opioid-related policies to characterise themes and subthemes.Results We describe two themes where coalitions and policy intersect: policy landscape barriers and navigation and mitigation strategies to address policy barriers. …”
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  3. 18183

    Updated Masses for the Gas Giants in the Eight-planet Kepler-90 System Via Transit-timing Variation and Radial Velocity Observations by David E. Shaw, Lauren M. Weiss, Eric Agol, Karen A. Collins, Khalid Barkaoui, Cristilyn N. Watkins, Richard P. Schwarz, Howard M. Relles, Chris Stockdale, John F. Kielkopf, Fabian Rodriguez Frustaglia, Allyson Bieryla, Joao Gregorio, Owen Mitchem, Katherine Linnenkohl, Adam Popowicz, Norio Narita, Akihiko Fukui, Michaël Gillon, Ramotholo Sefako, Avi Shporer, Adam Lark, Amelie Heying, Isa Khan, Beibei Chen, Kylee Carden, Donald M. Terndrup, Robert Taylor, Dasha Crocker, Sarah Ballard, Daniel C. Fabrycky

    Published 2025-01-01
    “…To determine accurate masses and orbital parameters for planets g and h, we combined 34 radial velocities (RVs) of Kepler-90, collected over a decade, with the Kepler transit data. We jointly modeled the transit times of the outer two planets and the RV time series, then used our two-planet model to predict their future times of transit. …”
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  4. 18184

    Association between exposure to per- and polyfluoroalkyl substances and kidney function: a population study by Xue Zhang, Yongping Cao, Xiaona Yang, Fei Ma, Hengyang Zhang, Wenwen Xiao

    Published 2025-03-01
    “…BackgroundThe relationship between per- and polyfluoroalkyl substances (PFAS) and kidney function markers remains uncertain.MethodsWe used PFAS detection data from 5,947 adults in NHANES 2005–2012. …”
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  5. 18185

    Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

    Published 2022-03-01
    “…Both in-house tissue microarray and open accessed The Cancer Genome Atlas data sets were used to evaluate the clinical relevance in pancreatic cancer prognosis.Results LTX-315 treatment inhibited PD-L1 expression and enhanced lymphocyte infiltration in pancreatic tumors. …”
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  6. 18186

    Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

    Published 2025-06-01
    “…There were no significant interactions between stroke subgroups by severity or syndrome. …”
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  7. 18187
  8. 18188

    A deep dive into the surgical and pharmacological considerations of obesity in chronic myeloid leukemia: a narrative review by Rola Ghasoub, Basant Elsayed, Maria Benkhadra, Giuseppe Saglio, Jorge Cortes, Mohamed Elmarasi, Engy Elsayed, Ahmed Adel Elsabagh, Ibrahim Elmakaty, Abdelrahman Elsayed, Mohamed Yassin, Mohamed Yassin

    Published 2025-07-01
    “…The review also examined the implications of obesity on CML patient outcomes and treatment milestones, aiming to establish a pathway for managing these patients.Results/DiscussionClinical data on CML management in obese patients is limited. …”
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  9. 18189

    Impacts of the local temperature anomalies over Mongolian Plateau on heavy rainfall events in north China during July 2023 by Yunchang Cao, Ling Zhang, Haijun Zhao, Zhun Guo

    Published 2025-06-01
    “…This mechanism has been thoroughly validated using the Interactive Global Grand Ensemble (TIGGE) dataset, that better forecasts of 237HRE usually benefited from better forecasts of the WPSH. …”
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  10. 18190

    Assessment of ecological environment quality and their drivers in urban agglomeration based on a novel remote sensing ecological index by Fangyuan Lu, Chen Zhang, Haoyu Cao, Xibin Wang, Tong Zheng, Zhenfang Huang

    Published 2025-01-01
    “…This study utilizes the Google Earth Engine (GEE) platform, integrates MODIS imagery and NPP-VIIRS data to develop a Novel Remote Sensing Ecological Index (NRSEI). …”
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  11. 18191

    Study on molecular mechanism of intervertebral disc degeneration by single cell hdWGCNA combined with transcriptome sequencing by Xuan Zhao, Qijun Wang, Wei Wang, Xiaolong Chen, Shibao Lu

    Published 2025-02-01
    “…Methods: We analyzed the single-cell data and screened cells that closely associated with the development of IVDD. …”
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  12. 18192

    Crisis Intervention Team Mental Health Training for Law Enforcement Officers: Protocol for a Multi‐Site, Randomized, Controlled Trial by Michael T. Compton, Elisabeth Jackson, En Fu, Howard F. Andrews, Ron Bruno, Erin Comartin, Hanga Galfalvy, Don Kamin, Leah G. Pope, Eduardo Vega, Amy C. Watson

    Published 2025-03-01
    “…Trained raters, blinded to site, treatment arm, and timepoint, will evaluate the primary outcome. Survey‐based data will capture officer characteristics and hypothesized mediators and moderators. …”
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  13. 18193

    Partial Niche Partitioning in Three Sympatric Gull Species Through Foraging Areas and Habitat Selection by Nina J. O'Hanlon, Gary D. Clewley, Daniel T. Johnston, Chris B. Thaxter, Samuel Langlois Lopez, Lucy R. Quinn, Philipp H. Boersch‐Supan, Elizabeth A. Masden, Francis Daunt, Jared Wilson, Niall H. K. Burton, Elizabeth M. Humphreys

    Published 2025-07-01
    “…We investigated the breeding season foraging ecology of three sympatric gull species, Lesser Black‐backed (Larus fuscus), Herring (Larus argentatus) and Great Black‐backed Gulls (Larus marinus), from the same colony in Scotland. Using GPS tracking data, we analysed foraging ranges, spatial distributions and habitat preferences to determine the extent of the gulls' niche partitioning and use of human‐modified landscapes. …”
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  14. 18194

    Impact of Patient Online Record Access on Documentation: Scoping Review by Eva Meier-Diedrich, Camilla Lyckblad, Gail Davidge, Maria Hägglund, Anna Kharko, Brian McMillan, Charlotte Blease, Julian Schwarz

    Published 2025-02-01
    “…ObjectiveThis scoping review aimed to examine potential subjective and objective changes in HCPs’ documentation after using patients’ ORA. MethodsA scoping review was conducted using a methodological framework for scoping reviews and data from 4 electronic databases. …”
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  15. 18195

    Determinants of implementation of a stepped care intervention for adolescents and youth living with HIV in Kenya: a qualitative evaluation by Nok Chhun, Dorothy I. Mangale, Kawango Agot, Winnie A. Owade, Julie Kadima, Jacinta Badia, James K. Kibugi, Pamela K. Kohler, Grace John-Stewart, Kristin Beima-Sofie

    Published 2025-05-01
    “…Supportive leadership was an important driver of implementation success, through availing space for mental health counseling sessions and time for client-provider interactions outside standard operating hours. Conclusions Consideration of alignment with national policy, integration into clinic workflows, school schedules, and leadership engagement, will be important for sustained use of differentiated care interventions. …”
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  16. 18196

    Understanding “Alert Fatigue” in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders by Illin Gani, Ian Litchfield, David Shukla, Gayathri Delanerolle, Neil Cockburn, Anna Pathmanathan

    Published 2025-02-01
    “…To ensure structured and practicable findings, we used a directed content analysis of the data, guided by the 7 domains of the Non-adoption, Abandonment, Scale-up, Spread, and Sustainability (NASSS) framework, including domains related to Technology, Adopter attitudes, and Organization. …”
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  17. 18197

    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity by Adrian Granda Farias, Brian Feng, Shahbaz Khan, Wayne Ngo, Jamie L.Y. Wu, Magali Aguilera-Uribe, Shan Grewal, Patricia Mero, Sheila K. Singh, Thomas Kislinger, Warren C.W. Chan, Jason Moffat

    Published 2025-07-01
    “…Our data are consistent with previous evidence but also implicate glutaminyl-peptide cyclotransferase-like (QPCTL) in cis CD47-SIRPA interactions. …”
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  18. 18198

    Photo-induced hydrous organic aggregates for photoactivatable luminescence by Zeyang Ding, Rufan Mo, Zonghang Liu, Ying Peng, Yixuan Chen, Xiao Li, Fulong Ma, Guoqing Zhang, Zheng Zhao, Parvej Alam, Bo Wu, Zijie Qiu, Ben Zhong Tang

    Published 2025-07-01
    “…Abstract Harnessing light to regulate molecular aggregation behavior has become an essential approach to confer useful properties for functional materials at the aggregate level. …”
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  19. 18199
  20. 18200

    Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia by Karima Schwab, Lianne Robinson, Anne Annschuetz, Eline Dreesen, Mandy Magbagbeolu, Valeria Melis, Franz Theuring, Charles R. Harrington, Claude M. Wischik, Gernot Riedel

    Published 2025-01-01
    “…The most prominent differences appeared in proteins of the SNARE complex (SNAP-25, VAMP-2, SNTX-1), but rivastigmine also interfered with the HMTM-dependent reduction in tau accumulation. These data extend our previous findings with L1 mice and provide evidence for a synaptic mechanism of interference between symptomatic and disease-modifying dementia therapies and an explanation for similar drug interactions observed in clinical trials.…”
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