Research discussion groups as a component of the development of practical skills of students in the field of training “Construction” by N. I. Taraseeva, O. V. Baulina, N. A. Dezhinova

“…At the same time, significant assistance is provided by the use of modern teaching methods through long distance education, including systems of electronic educational and methodical complexes of disciplines and practices; systems that provide interactive communication of all subjects of the educational process, including industrial enterprises.The purpose of this article is to analyze the efficiency of research discussion groups in educational institutions of the construction areas with the aim of generating interest in the chosen occupation, the development of creative skills of the talented youth, opportunities to exercise their author’s ideas and inventive work “products" on the market of goods and services, as well as the development implementation into the educational process of schools and attract pupils to project work in view of the networking cooperation on the regional cyber platform. …”
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Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications by Wei Xia, Miao Ye, Bo Jiang, Gang Xu, Guancheng Xiao, Qingming Zeng, Ruohui Huang

“…The ‘clustanoikisProfilanoikis’ and ‘GSEA’ packages were used to explore potential ARG-related pathways.ResultsAnalyzing 553 samples from TCGA, 231 from MSKCC, 94 from GSE70769, and single-cell data from 6 prostate cancer patients (GSE137829), we constructed a prognostic model based on 9 ARGs. …”
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Riparian habitat quality and seasonality drives spatiotemporal habitat ecology of sympatric Asian otters in southern Western Ghats by Ankit Moun, Tharmalingam Ramesh, Tharmalingam Ramesh, Riddhika Kalle, Riddhika Kalle

“…In dynamic ecosystems, we have scant knowledge on the interactive role of season and local riparian habitat conditions in driving spatiotemporal habitat use of sympatric semi-aquatic mustelids.MethodologyWe conducted seasonal monitoring of 169-196 riverine segments (250 m) in 2020 and 2021 to measure the sign encounter rates of Asian small-clawed otter (SCL) and smooth-coated otter (SCO) and recorded 29 riparian habitat variables.ResultsOur self-organizing map algorithm characterized alarge multivariate habitat data into six habitat clusters representing a gradient of riparian habitat conditions. …”
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Comparing the Fate of eDNA by Particle Sizes and Molecule Lengths in Recirculating Streams by Pedro F. P. Brandão‐Dias, Elise Snyder, Jennifer L. Tank, Ursula H. Mahl, Brett Peters, Arial J. Shogren, Diogo Bolster, Gary A. Lamberti, Kyle Bibby, Scott P. Egan

“…ABSTRACT The detection of environmental DNA (eDNA) has revolutionized aquatic species monitoring, yet interpreting eDNA data remains challenging due to gaps in our understanding of eDNA ecology (i.e., origin, state, transport, and fate) and variability in how eDNA methods are applied across the literature. …”
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Comparative analysis of national innovation systems: Implications for SMEs' adoption of fourth industrial revolution technologies in developing and developed countries by Lebogang Mosupye-Semenya

“…Our study aims to fill these gaps by employing Lundvall’s framework to explore both developed and developing countries’ systems comprehensively. METHODOLOGY: The data was collected through a Systematic Literature Review, identifying a total of 695 publications from SCOPUS, Web of Science (WoS), and ProQuest. …”
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Integrated proteomics and metabolomics network analysis across different delivery modes in human pregnancy: a pilot study by Yun Huang, Yanyan Ni, Yu Meng, Xiaojing Zeng, Xiaoqing He, Lin Zhang, Jun Zhang

“…We used weighted gene co-expression network analyses (WGCNA) to identify modules of highly correlated proteins or metabolites that associated with delivery modes and related clinical traits. …”
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Periodontal health intervention for oral health-related outcomes in older type 2 diabetes patients: a randomized controlled trial in a Chinese tertiary hospital by Chunxiu Xiao, Lan Zhang, Zhaoxi Li, Qingnv Xu, Suping Lin, Siyu Zheng, Hanping Shi

“…Demographic questionnaires, Plaque Index (PLI), Geriatric Oral Health Assessment Index (GOHAI), Periodontal Health Knowledge, Attitude, and Behavior Questionnaire, as well as the Oral Hygiene Index-Simplified (OHI-S) (including Debris Index-Simplified (DI-S) and the Calculus Index-Simplified (CI-S)) were used to collect data. Statistical analysis was performed using Chi-square tests, Fisher’s exact tests, and SPSS software version 27. …”
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In Vitro Shoot Regeneration of Oil Seed Crop Sesamum indicum L. from Seedling Cotyledon Explant to Lay Ground for Genetic Transformation in Ethiopia by Micheale Yifter Weldemichael, Yemane Tsehaye Bayratsion, Desta Berhe Sbhatu, Girmay Gebresamuel Abraha, Hagos Mohammedseid Juhar, Abraha Birhan Kassa, Fiseha Baraki Sibhatu, Birhanu Debesay Berhe, Tagel Elias Sahle, Mohammed Mebrahtu Mossa, Haftay Abadi Gebru

“…This study was conducted to develop an efficient regeneration protocol used for sesame genetic transformation. Published regeneration methods using 6-benzylaminopurine (BAP), indol-3-butyric acid (IBA), and α-naphthaleneacetic acid (NAA) were used in this experiment. …”
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An international consensus panel on the potential value of Digital Surgery by Anita Patel, Giuseppe Turchetti, Guy Maddern, Ataru Igarashi, Prasanna Sooriakumaran, Gretchen Purcell Jackson, Anastasia Chalkidou, Jamie Erskine, Jean-Christophe Bernhard, Payam Abrishami, Richard Charter, Richard Culbertson, Jo Carol Hiatt, Matthew Lien, Joseph Soon Yau Ng, Koon Ho Rha, Scott Tackett

“…Consensus was defined as a mean level of agreement of >7.Results Four priority topics were identified: (1) how data are used in digital surgery, (2) the existing evidence base for digital surgical technologies, (3) how digital technologies may assist surgical training and education and (4) methods for the assessment of these technologies. …”
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Risk Perception and Knowledge Following a Social Game–Based Tobacco Prevention Program for Adolescents: Pilot Randomized Comparative Trial by Georges Khalil, Erica Ramirez, Meerah Khan, Bairu Zhao, Nuno Ribeiro, Patrick Balian

“…ObjectiveThis pilot study aims to (1) compare the social game–based program Storm-Heroes to a nonsocial program regarding adolescents’ personal and social experiences and (2) examine how these experiences predict higher tobacco knowledge and perceived risks of vaping and conventional tobacco use. MethodsIn a cluster-randomized comparative design, 4 after-school sites (N=79 adolescents) were recruited in person and randomized in a single-blinded format to 1 of 2 interventions: the social game Storm-Heroes (44/79, 56%) or the nonsocial program A Smoking Prevention Interactive Experience (ASPIRE; 35/79, 44%). …”
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APOE4 triggers dysregulated synaptic vesicle release by disrupting SNARE complex assembly by Feng Chen, Yanting Chen, Sifan Feng, Huiyi Chen, Liehua Deng, Fubin Ma, Qiongwei Ke, Qiuhao Liang, Ji Chen, Xiaoping Peng, Jiongtong Lu, Yingxuan Liu, Yuying Xie, Hao Cao, Yuanhong Sun, Wenxian Wu, Lili Cui, Yan Wang

“…Impaired synaptic transmission is one of the common pathogenic features of neurodegenerative diseases. By using proteomics analysis, co-immunoprecipitation (Co-IP), and bimolecular fluorescence complementation (BiFC) assay, we demonstrated that APOE interacts with VAMP2, a core component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, in an APOE4 > APOE3 manner. …”
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Single-cell sequencing uncovers disrupted stromal-macrophage communication as a driver of intrauterine adhesion progression by E. Dong, Zhengli Zhou, Tingwei Chen, Bo Zhang, Yu Yin, Xiaomei Wu, Xiaozhuo Li, Jingxue Zhao, Yan He, Jie Yang, Ting Liu, Naixue Yang, Ran Zhu, Lujuan Rong, Jiwen Tian, Wenshu Zhou, Tianqing Li

“…Integration with secretory-phase single-cell data provides a comprehensive view of IUA across menstrual phases. …”
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Integrated spatial omics of metabolic reprogramming and the tumor microenvironment in pancreatic cancer by Hao Wu, Qiyao Zhang, Zhen Cao, Hongtao Cao, Mengwei Wu, Mengdi Fu, Tingping Huang, Xianlin Han, Xiaoyan Chang, Ziwen Liu

“…By integrating single-cell transcriptomics, spatial transcriptomics, and spatial metabolomics, this study visualized the spatial co-localization of metabolites and gene expression within tumor samples, uncovering metabolic heterogeneity and intercellular interactions. Spatial transcriptomics identified distinct pathological regions, which were further characterized using single-cell transcriptomic data and pathologist annotations. …”
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Factors associated with discharge from hospital to residential aged care for younger people with neuropsychiatric disorders: an exploratory case–control study in New South Wales, A... by Simone Reppermund, Preeyaporn Srasuebkul, Julian Trollor, Di Winkler, Brian Draper, Rachael Cherie Cvejic, Tim R Watkins, Adrian R Walker, Adrienne Withall, Ingrid Honan, Deidre Mackechnie

“…We calculated ORs for sociodemographic and diagnostic factors to determine factors that may impact discharge to RAC.Results During the period of data capture, 4406 people were discharged from hospitals to RAC. …”
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1-Hexadecyl-3-methylimidazolium tetrachloroindate ionic liquid as corrosion inhibitor for mild steel: Insight from experimental, computational, multivariate statistics and multi-qu... by Ndidiamaka Martina Amadi, Joseph Okechukwu Ezeugo, Chukwunonso Chukwuzuluoke Okoye, John Ifeanyi Obibuenyi, Maduabuchi Arinzechukwu Chidiebere, Dominic Okechukwu Onukwuli, Valentine Chikaodili Anadebe

“…The combine electrochemical approach suggested a mechanism influenced by electron transfer, underscoring the IL's as a mixed-type inhibitor. The experimental data based on weight loss was optimized using response surface methodology (RSM). …”
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Micronutrients are drivers of abundance, richness, and composition of soil insect communities in tropical rainforests by Miquel Ferrín, Dolores Asensio, Albert Gargallo‐Garriga, Oriol Grau, Joan Llusià, Laura Màrquez, Jérôme Murienne, Romà Ogaya, Jérôme Orivel, Jordi Sardans, Ivan A. Janssens, Josep Peñuelas, Guille Peguero

“…However, we found different relationships when analyzing the data separately for Blattodea, Coleoptera, Hemiptera, Hymenoptera, and Orthoptera, the most abundant insect orders with the most OTUs. …”
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Hillslope flow paths in snowmelt and rainfall seasons in permafrost-underlain areas, Northeastern Tibetan Plateau: Investigation based on hydrochemical tracers and end-member mixin... by Xiong Xiao, Fan Zhang, Fengjing Liu, Xiaoyan Li, Xiaonan Shi, Chen Zeng, Tao Che

“…Study focus: Hillslope flow paths were studied using hydrochemical data of various water types in the spring snowmelt and summer rainfall periods based on hydrochemical tracers and end-member mixing analysis. …”
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Combination checkpoint blockade for metastatic cutaneous malignancies in kidney transplant recipients by Richard Carvajal, Yvonne Saenger, Matthew Ingham, Shaheer Khan, Diana McDonnell, Megan H Trager, Shana M Coley, Geoffrey Dube, Faramarz H Samie, Larisa J Geskin, Daniel Brouder

“…Nivolumab blocks the interactions between programmed cell death protein 1 and programmed death ligand 1 allowing for activation of a latent immune response against the malignancy. …”
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Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization by Jiaxin Wang, Ning Li, Xueyu Cang, Xuerong Liu, Ranyan Gao, Lingyi Xu, Fengchun Li, Xinyu Jiang, Hongliang Chen, Xinyu Geng, Jihan Qi, Ram Prasad Chaulagain, Junchong He, Shizhu Jin

“…Here, we identified TLR-related genes, providing novel insights related to LC diagnosis, pathogenesis, and treatment. Data from public databases were analyzed using “limma” and WGCNA to screen candidate genes, and four hub genes (CXCL9, CXCL10, SPP1, CTSK) were selected through machine learning. …”
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Synthesis, structural elucidation, and antimicrobial evaluation of (2E)-3-(4-fluorophenyl)-1-(4-isopropylphenyl)prop-2-en-1-one: insights from experimental and computational studie... by Nutan V. Sadgir, Vishnu A. Adole, Sunil L. Dhonnar, Bapu S. Jagdale, Kailas H. Kapadnis, Jayesh Pawar

“…DFT/B3LYP calculations with a 6–311++G(d,p) basis set showed strong agreement with experimental data, confirming the reliability of the computational approach. …”
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