Genetic evidence for causal relationships between vegetarian biomarkers and esophageal cancer risk by Xinqi Liu, Xu Xu, Zhenglong Jiang, Ning Du, Jiayang Chen, Jinyuan Chang, Lixing Liu, Li Feng

“…Methods We leverage genetic approaches to investigate the bidirectional causal relationships between vegetarian-specific biomarkers and EC risk. Using genome-wide association study (GWAS) data from European populations, we performed Mendelian randomization (MR) analyses on vegetarian biomarkers as exposures and EC as the outcome, with validation in an independent EC cohort. …”
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The Importance of Telemedicine during COVID-19 Pandemic: A Focus on Diabetic Retinopathy by Raffaele Galiero, Pia Clara Pafundi, Riccardo Nevola, Luca Rinaldi, Carlo Acierno, Alfredo Caturano, Teresa Salvatore, Luigi Elio Adinolfi, Ciro Costagliola, Ferdinando Carlo Sasso

“…Lack of data during the COVID-19 pandemic strongly limits the possibility of tracing the real management of the disease, which is only conceivable from past evidence in normal conditions. …”
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Seasonal Variations of Soil Thermal Conductivity at the InSight Landing Site by M. Grott, S. Piqueux, T. Spohn, J. Knollenberg, C. Krause, E. Marteau, T. L. Hudson, F. Forget, L. Lange, N. Müller, M. Golombek, S. Nagihara, P. Morgan, J. P. Murphy, M. Siegler, S. D. King, D. Banfield, S. E. Smrekar, W. B. Banerdt

“…Therefore, any cementation or induration of the soil sampled by the experiments must be minimal and soil surrounding the mole at depths below the duricrust is likely unconsolidated. Thermal conductivity data presented here are the first direct evidence that the atmosphere interacts with the top most meter of material on Mars.…”
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Diseño de un Software de Intermediación de Comunicación para Sistemas Distribuidos de Tiempo Real Críticos en Java by Daniel Tejera, Alejandro Alonso, Miguel A. de Miguel

“…A relevant subset of them is high-integrity or hard real-time systems, where failure can cause loss of life, environmental harm, or significant financial loss.Additionally, the evolution of communication networks and paradigms as well as the necessity of demanding processing power and fault tolerance, motivated the interconnection between electronic devices; many of the communications have the possibility of transferring data at a high speed. The concept of distributed systems emerged as systems where different parts are executed on several nodes that interact with each other via a communication network.Java's popularity, facilities and platform independence have made it an interesting language for the real-time and embedded community. …”
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Comprehensive analysis of the electronic, thermodynamic, and spectroscopic properties of a Cu(II)-based complex with 1,10-phenanthroline and L-glutamine by Marinaldo V. Souza Junior, João G. Oliveira Neto, Walajhone O. Pereira, Jéssica A.O. Rodrigues, Jailton R. Viana, Aramys S. Reis, Mateus R. Lage, Guilherme G.C. Carvalho, Cláudia O. Pessoa, Adenilson O. dos Santos, Francisco F. de Sousa

“…A computational analysis of the intermolecular interactions using Hirshfeld surfaces was also performed, which demonstrated that the H⋯O/O⋯H and H⋯H interactions are mainly responsible for the structural and thermal stability of the complex. …”
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Early Intervention for Children With Developmental Disabilities and Their Families via Telehealth: Systematic Review by Yoomi Shin, Eun Ju Park, Anna Lee

“…Study quality was assessed using the mixed methods appraisal tool, and a narrative synthesis was used to analyze the data. …”
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Conversational Systems for Social Care in Older Adults: Protocol for a Scoping Review by Rosiered Brownson-Smith, Ananya Ananthakrishnan, Oksana Hagen, Cen Cong, Amir Aly, Ray B Jones, Edward Meinert

“…These technologies can offer intuitive interactions, particularly for individuals with limited digital literacy. …”
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Ultra-High-Energy Cosmic Rays Accelerated by Magnetically Dominated Turbulence by Luca Comisso, Glennys R. Farrar, Marco S. Muzio

“…We fit the Pierre Auger Observatory’s spectrum and composition measurements, taking into account particle interactions between acceleration and detection, and show that the turbulence-associated energy cutoff is well supported by the data, with the best-fitting spectral index being $s={2.1}_{-0.13}^{+0.06}$ . …”
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Tracing the dynamic changes in the lncRNA-mediated competing endogenous RNA network during bovine preimplantation embryo development by Yuan Fan, Krishna Chaitanya Pavani, Osvaldo Bogado Pascottini, Bart J.G. Broeckx, Katrien Smits, Ann Van Soom, Luc Peelman

“…In this study, we revisited existing RNA sequencing and small RNA sequencing data to investigate the role of lncRNAs in in vitro–produced bovine preimplantation embryos. …”
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3D Acoustic Remote Sensing mapping of the Underwater Cultural Heritage in the Marine Protected Area of Baia submerged Park (Bay of Pozzuoli, Southern Italy) by C. Violante, N. Abate, D. Ferdani, N. Masini, E. Gallocchio, A. Pagano, F. Pagano

“…These methods are efficient in data acquisition and yield results that are both repeatable and quantifiable.…”
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Empowering China’s sustainable development through social-ecological networks by Wuyang Hong, Yelin Li, Renzhong Guo, Bin Chen, Wenjia Zhang, Feixue Li, Shuwen Yang, Yuke Liu, Yingmei Zhao, Yurui Li, Shengbiao Wu, Biao He

“…Results show that 69.5% of the planned networks are supported by LUCC data; however, 10.4% of county nodes were overlooked by the spatial plans. …”
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Gamifying Resistance Training with Wearable Sensors by Cheuk-Yan Au, Chee Ming Noel Sng, Jeshuan Heng, Thanh Tam Nguyen, Joo Chuan Yeo, Ali Asgar Saleem Bhagat

“…In this work, we develop a gamified resistance training program using wearable sensors to explore the potential benefits of interactive and data-driven exercise experiences. …”
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Streamflow changes and warming climate-induced flood risks for 1960–2016 in the Nenjiang River Basin, northeastern China by Mengyuan Wang, Suocheng Dong, Ping Wang, Zehong Li, Shiqi Liu, Shuwen Zhang, Jie Mei

“…This study investigated long-term streamflow trends, influencing factors, responses to climate change, and future flood risks in the Nenjiang River Basin, a typical mid-latitude region in Northeast China that is highly sensitive to droughts and floods. Using data from 1960 to 2016, we applied the Mann–Kendall trend and mutation tests and random forest models, and modeled streamflow responses to climate change to explore streamflow–climate interactions. …”
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On the Extended Soft X-Ray and Fe Kα Emission in NGC 1068 by Songbo Gao, Hongxing Yin, Shaoming Hu

“…We present a detailed spatially resolved image and spectral analysis of the Seyfert 2 galaxy NGC 1068 using high-resolution Chandra ACIS data. We find that the soft X-ray emission and iron emission show extended structures in the northeast and southwest directions. …”
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Living with pain and Parkinson’s developing an understanding of the impact, trajectory and pain management needs: a qualitative interview study protocol by Darren Flynn, Lynn Rochester, Richard Walker, Tracy Finch, Cormac Ryan, Alison Yarnall, Leah Avery, Annette Hand, Katherine Baker, Jenni Naisby, Mark Parkinson

“…Therefore, it is pertinent to speak to PwP to understand their experiences of pain to inform the development of tailored behavioural interventions to manage pain. How pain interacts with other Parkinson’s symptoms lacks consensus. …”
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Association between a dietary index for gut microbiota and breast cancer history in adult women: findings from NHANES 2011–2020 by Zhiwei Fan, Liang Li, Lingling Bu, Zhihui Geng, Song Liu

“…The aim was to investigate the association between a gut microbiota–oriented dietary index (DI-GM) and breast cancer risk among U.S. women.MethodsThis cross-sectional study analyzed data from 6,083 women aged ≥20 years from NHANES 2011–2020. …”
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Deep proteome profiling of metabolic dysfunction-associated steatotic liver disease by Felix Boel, Vyacheslav Akimov, Mathias Teuchler, Mike Krogh Terkelsen, Charlotte Wilhelmina Wernberg, Frederik Tibert Larsen, Philip Hallenborg, Mette Munk Lauridsen, Aleksander Krag, Susanne Mandrup, Kim Ravnskjær, Blagoy Blagoev

“…A deeper understanding of disease pathogenesis is essential to assist in developing blood-based biomarkers. Methods Here, we use data-independent acquisition mass spectrometry to assess disease-state associated protein profiles in human liver, blood plasma, and white adipose tissue (WAT). …”
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Identification of Novel Progesterone Receptor (PR) Inhibitors (<i>Homo sapiens</i>) from Metabolites of Biotransformation Fungal: A Bioinformatics Approach by Janaína de Araújo E. Dourado, Samuel Q. Lopes, David Esteban Q. Jimenez, Ryan S. Ramos, Irlon M. Ferreira

“…<b>Results:</b> Androstenedione, 17α-hydroxyprogesterone, and dihydrotestosterone, obtained by the process of biotransformation of PR by different filamentous fungi, showed good pharmacokinetic profiles and low toxicity compared to the control groups. The in-silico data associated with molecular docking studies revealed the best binding affinity and similarity in the interactions of these molecules against the human progesterone receptor target. …”
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Linking abiotic conditions to mosquito assemblage structure in bromeliads by Antônio Ralph Medeiros-Sousa, Rafael de Oliveira-Christe, Walter Ceretti-Junior, Karolina Morales Barrio-Nuevo, Eduardo Evangelista, Ramon Wilk-da-Silva, Luis Filipe Mucci, Marcia Bicudo de Paula, Mauro Toledo Marrelli

“…Relationships between variables were tested using generalized linear mixed-effects models and structural equation modeling (Piecewise SEM). …”
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Experimental Insights and Recommendations for Successfully Performing Cerebral Microdialysis With Hydrophobic Drug Candidates by Julia K. Sundheimer, Julia Benzel, Rémi Longuespée, Jürgen Burhenne, Stefan M. Pfister, Kendra K. Maaß, Max Sauter, Kristian W. Pajtler

“…However, obtaining valid and accurate microdialysis data can be particularly challenging for hydrophobic drugs due to their pronounced non‐specific interactions with the components of the microdialysis system. …”
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