Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer’s Disease Therapy by Junyu Zhou, Chen Li, Yong Kwan Kim, Sunmin Park

“…We employed the bioinformatics-integrated deep neural analysis of NCs for Disease Discovery (BioDeepNat) application in the data collected from chemical databases. Random forest regression models were utilized to predict the IC₅₀ (pIC₅₀) values of ligands interacting with AD-related target proteins, including acetylcholinesterase (<i>AChE</i>), amyloid precursor protein (<i>APP</i>), beta-secretase 1 (<i>BACE1</i>), microtubule-associated protein tau (<i>MAPT</i>), presenilin-1 (<i>PSEN1</i>), tumor necrosis factor (<i>TNF</i>)<i>-α</i>, and valosin-containing protein (<i>VCP</i>). …”
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Compassion fatigue in helping professions: a scoping literature review by Amelia Mohd Noor, Dodi Suryana, Engku Mardiah Engku Kamarudin, Noor Banu Mahadir Naidu, Siti Rozaina Kamsani, Priyalatha Govindasamy

“…Methods A systematic search was conducted on electronic databases, namely ScienceDirect, PubMed, and Taylor and Francis. Data analysis was conducted using PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). …”
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Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro... by Yuchao Jia, Haifan Zhao, Shengbo Huang, Baoshan Xu

“…Methods Mendelian randomization (MR): GWAS data was employed to assess causal associations between proton pump inhibitors (PPIs) and IVDD. …”
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The Relation Between Learning Engagement and Academic Self-Efficacy Toward Academic Achievement among University Students by Hong-Ping Pang, Arsaythamby Veloo

“…The data was analyzed using t-tests, one-way ANOVA and regression analysis. …”
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Quantitative proteomic studies of the intestinal mucosa provide new insights into the molecular mechanism of ulcerative colitis by Yandong Guo, Dahal Pabitra, Lei Pan, Lanbo Gong, Aimin Li, Side Liu, Jing Xiong

“…Subsequent verification of the 9 DEPs by PRM confirmed the reliability of the mass spectrometry data. TXNDC5 expression was significantly increased in UC. …”
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Cultural narratives, social norms, and psychological stigma: a study of mental health help-seeking behavior in Peshawar, Pakistan by Umar Daraz, Štefan Bojnec, Štefan Bojnec, Štefan Bojnec, Younas Khan, Zakir Hussain

“…Data were collected using culturally validated instruments, including the Mental Illness Stigma Scale (MISS) and a Social Norms Scale. …”
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Patient lumbar discectomy journey (DiscJourn) in the UK: a qualitative study by Alison B Rushton, Nicola R Heneghan, Louise White, Navin Furtado, Annabel Masson, Karl Baraks, Zeeshan Parvez

“…Semi-structured interviews were conducted using a patient co-constructed topic guide. Interview transcriptions were analysed in accordance with IPA. …”
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Association between admission Braden Skin Score and delirium in surgical intensive care patients: an analysis of the MIMIC-IV database by Meiling Shang, Meiling Shang, Ailing Shang, Yu Xu, Yu Xu

“…This study aimed to explore the association between BSS upon admission and the risk of delirium in SICU patients.MethodsThis retrospective observational cohort study used data from the Medical Information Mart for Intensive Care (MIMIC)-IV database. …”
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Extracting Knowledge from Machine Learning Models to Diagnose Breast Cancer by José Manuel Martínez-Ramírez, Cristobal Carmona, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos

“…This study explored the application of explainable machine learning models to enhance breast cancer diagnosis using serum biomarkers, contrary to many studies that focus on medical images and demographic data. …”
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Investigation of genetic variants, birthweight and hypothalamic-pituitary-adrenal axis function suggests a genetic variant in the SERPINA6 gene is associated with corticosteroid bi... by Laura N Anderson, Laurent Briollais, Helen C Atkinson, Julie A Marsh, Jingxiong Xu, Kristin L Connor, Stephen G Matthews, Craig E Pennell, Stephen J Lye

“…The associations between 124 tag single nucleotide polymorphisms (SNPs) within 16 HPA pathway candidate genes and each hormone were evaluated using multivariate linear regression and penalized linear regression analysis using the HyperLasso method.…”
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Effects of permeability, grid resolution, and carbonate reactions on CO2 distribution and sulphate scaling in seawater-flooded carbonates by Ali M. Al-Behadili, Eric J. Mackay

“…Oilfield data have been used to identify the parameters of significance to consider in the calculations, such as ionic concentrations, hydrocarbon composition, mineral components etc. …”
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‘We don’t get money in our own hands’: evidence from focus group discussions on economic abuse against women in two states of India by Sangeeta Chatterji, Janina Isabel Steinert, Ines Boehret, Rucha Vasumati Satish, Sanchita Sharma

“…This paper presents rich qualitative data on economic abuse against women in India to improve the understanding of economic abuse in a lower-middle income setting and to assess how economic abuse interacts with socio-cultural factors such as patrilocality, patriarchal gender norms and limited acceptance of female employment.Methods We conducted 13 focus group discussions (FGDs) in the states Maharashtra and Rajasthan. …”
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The influence of childhood abuse, adult life events, and affective temperaments on the well-being of the general, nonclinical adult population by Kanai Y, Takaesu Y, Nakai Y, Ichiki M, Sato M, Matsumoto Y, Ishikawa J, Ono Y, Murakoshi A, Tanabe H, Kusumi I, Inoue T

“…We hypothesized that childhood abuse, affective temperaments, and adult life events interact with one another and influence positive and negative affects in the general adult population and tested this hypothesis using structural equation modeling. …”
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Social isolation in the young and middle-aged patients with stroke: role of social support, family resilience and hope by Xiao Jia Wu, Ke Ke, Hui Liu, Shao Ping Zhan, Lei Wang, Juan Feng He

“…SPSS 27.0 and AMOS 26.0 were used for descriptive analysis and structural equation modeling of the data.ResultsThe young and middle-aged stroke survivors had a high level of social isolation(49.57 ± 5.84). …”
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Targeting Key Risk Factors for Cardiovascular Disease in At-Risk Individuals: Developing a Digital, Personalized, and Real-Time Intervention to Facilitate Smoking Cessation and Phy... by Anke Versluis, Kristell M Penfornis, Sven A van der Burg, Bouke L Scheltinga, Milon H M van Vliet, Nele Albers, Eline Meijer

“…A total of 6 different approaches were used and combined to support the development of the Perfect Fit VC. …”
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Transformational leadership and innovative work behavior: The sequential mediating role of knowledge sharing and creative self-efficacy by Ni Nyoman Suliati, Noermijati, Achmad Sudiro, Desi Tri Kurniawati

“…This study surveyed 377 hotel employees, selected using the Krejcie and Morgan (1970) formula. Data collected from December 2024 to February 2025 were analyzed using structural equation modeling with a partial least squares approach. …”
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Equipes virtuais: um estudo de caso na indústria têxtil norte-americana Virtual teams: a case study in an u.s. textile company by Viviane Carvalho Bejarano, Luiz Alberto Pilatti, Luciano Scandelari, Antonella Carvalho de Oliveira

“…This study analyzes the variables that can intervene in the implementation of virtual teams, through the case of a virtual team structured to operate a textile distribution center. Research instruments used for data collection: participant observation, documental analysis and questionnaires with members of the virtual team. …”
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Diversity and Composition of Gastrointestinal Helminths and Gram-Negative Bacteria of the West African Rainbow Lizard (Agama picticauda) in a Human-Modified Landscape: Implications... by Benjamin Y. Ofori, Juliet M. Ewool, Rachel E. A. Asamoah, Philomina A. Adarkwah, Daniel Oduro

“…Some Ascaris spp., Enterobius spp., Escherichia spp., Enterobacter spp., Shigella spp., and Salmonella spp. are found in humans. Our data can serve as baseline information for long-term monitoring studies of reptile-parasites-environment interactions in the Accra plains of Ghana. …”
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MTL-PlotCounter: Multitask Driven Soybean Seedling Counting at the Plot Scale Based on UAV Imagery by Xiaoqin Xue, Chenfei Li, Zonglin Liu, Yile Sun, Xuru Li, Haiyan Song

“…Accurate and timely estimation of soybean emergence at the plot scale using unmanned aerial vehicle (UAV) remote sensing imagery is essential for germplasm evaluation in breeding programs, where breeders prioritize overall plot-scale emergence rates over subimage-based counts. …”
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Development of a complex palliative care intervention for patients with heart failure and their family carers: a theory of change approach by Bader Nael Remawi, Nancy Preston, Amy Gadoud

“…Subsequently, analysis of secondary data on patient and carer experiences with palliative care services was presented to stakeholders to refine the proposed theory. …”
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